1-Bromo-5-Chloro-2-Fluorobenzene
Linshang Chemical
HS Code |
194366 |
Chemical Formula | C6H3BrClF |
Appearance | Colorless to light yellow liquid |
Boiling Point | 195 - 197 °C |
Melting Point | N/A |
Density | 1.729 g/mL at 25 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Flash Point | 76.7 °C |
Vapor Pressure | Low at room temperature |
Stability | Stable under normal conditions |
As an accredited 1-Bromo-5-Chloro-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100 g of 1 - bromo - 5 - chloro - 2 - fluorobenzene packaged in a sealed glass bottle. |
Storage | 1 - bromo - 5 - chloro - 2 - fluorobenzene should be stored in a cool, dry, well - ventilated area, away from direct sunlight. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials like glass. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to prevent potential reactions. Ensure proper labeling for easy identification. |
Shipping | 1 - bromo - 5 - chloro - 2 - fluorobenzene is shipped in tightly sealed, corrosion - resistant containers. It's transported with proper labeling, following hazardous chemical shipping regulations to ensure safe transit. |
Competitive 1-Bromo-5-Chloro-2-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1-Bromo-5-Chloro-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Mercury, which is liquid at room temperature, is a silver shiny metal. Its density is quite high, reaching 13.59 grams/cubic centimeter, so it can gather into silver bright droplets on the plane. Excellent fluidity, because of its strong cohesion and high surface tension, about 486.5 mN/m, ranks among the top of common liquids, making it easy to roll. Mercury has a melting point of -38.87 ° C and a boiling point of 356.6 ° C. This melting point is extremely low, making it liquid at room temperature and maintaining a liquid state in a wide temperature range. It can expand and contract according to temperature changes in the thermometer, accurately indicating the temperature. Mercury has good electrical and thermal conductivity. Although it is inferior to metals such as copper and silver, it is excellent in liquid metals and can conduct current. It is used in some electrical switches and electrodes. However, mercury is volatile and can evaporate into mercury vapor at room temperature, and mercury and its compounds are very toxic. Careless inhalation or contact can cause serious health damage.
Bromine is the only non-metallic element that is liquid at room temperature and pressure. It is dark reddish-brown, has a pungent smell, and is highly corrosive. Density 3.119 g/cm3, heavier than water, can sink to the bottom. Melting point -7.2 ° C, boiling point 58.78 ° C, volatile at room temperature, forming reddish-brown bromine vapor. Bromine is slightly soluble in water and easily soluble in organic solvents, such as carbon tetrachloride, benzene, etc. Its solubility in organic solvents far exceeds that of water, and the color of the solution varies depending on the concentration. Its chemical properties are active, strong oxidizing, and can react with many metals and non-metals.
Gallium Indium Tin alloy is also a common liquid metal. The melting point is usually lower than room temperature. According to the proportion of components, the melting point can be as low as about 15 ° C, so it is liquid at room temperature. The alloy has good fluidity and low surface tension. It can spread into a thin liquid film on a solid surface, which is conducive to infiltrating the surface of the material. Its electrical conductivity is excellent, similar to that of traditional metal conductors, and it can be used as a special conductive material in the field of electronics. In addition, the alloy has good thermal conductivity and can transfer heat efficiently, which can And compared with mercury, gallium indium tin alloy has lower toxicity, better environmental friendliness, and less harm to human body and environment when used.
Mercury is a liquid metal at room temperature, commonly known as mercury. It is heavy, silver-white in color and has a metallic luster. The chemical properties of mercury are relatively stable, and it can react when it encounters strong oxidizing agents. Mercury easily combines with sulfur, and the two combine to form mercury sulfide. This reaction is often used to remove mercury. And mercury vapor is toxic, and inhalation into the human body can cause serious health damage.
Bromine is a liquid non-metallic elemental substance, reddish-brown, with a strong pungent odor and strong volatility. Bromine is chemically active and a strong oxidizing agent. In chemical reactions, it often captures electrons. Bromine can react with many metals and non-metals. If it encounters sodium metal, it reacts violently to form sodium bromide.
Hydrobromic acid is an aqueous solution of hydrogen bromide and is a strong acid. It has the common properties of acids and can react with active metals to release hydrogen; neutralize with bases to form salts and water; react with metal oxides to form salts and water. Hydrobromic acid is corrosive and can corrode many metals and materials.
As for the interaction between these substances, mercury and bromine can react to form mercury bromide. Hydrobromic acid and mercury can also react under specific conditions. Although bromine and hydrobromic acid are relatively stable under general conditions, reactions may occur when specific catalysts or conditions change. The chemical properties of these substances are complex and wonderful, and they have important research value and application scenarios in the field of chemistry.
Mercury, also known as mercury, is a liquid metal. Its uses are quite extensive. In ancient times, it was often used in alchemy. The alchemists wanted to use it to refine the medicine of longevity. Although it was unsuccessful, it also promoted the development of ancient chemistry to a certain extent. In the medical field, mercury was used to make thermometers in the past, which used its characteristics of thermal expansion and contraction to accurately measure body temperature. However, due to its toxicity, it has gradually been replaced. In the chemical industry, mercury can be used to make amalgam, which is used in the manufacture of batteries and other products.
Boron is a non-metallic element. Borax is a common compound. In ancient times, it was often used in ceramic firing, which can make the surface of ceramics smoother, brighter in color, and improve the quality of ceramics. In modern times, boron and its compounds play a significant role in the metallurgical industry, and can be used as additives to enhance the hardness and strength of metals. At the same time, boron is also used in the field of agriculture. Appropriate amount of boron fertilizer can promote the growth of plant roots and improve crop yield and quality.
Diatoms are a type of single-celled algae. Their remains are piled up to form diatomaceous earth, which has various uses. In ancient times, its adsorption properties may have been observed. Although the use has not been clearly recorded, it may have simple applications. In modern times, diatomaceous earth is often used for filtration due to its good adsorption properties, such as in the brewing process of beer, which can filter impurities and make beer clearer. In the field of building materials, diatomaceous earth can be used to make environmentally friendly coatings, because it has the functions of absorbing odors and adjusting humidity, and can create a comfortable living environment.
In summary, 1 + mercury-5 + boron-2 + diatoms play an important role in different fields, from ancient exploration to modern wide application, which has far-reaching impact on human production and life.
First, the electrophilic substitution reaction is used as the base. The benzene ring is electron-rich and vulnerable to electrophilic attack. First, benzene is taken as the initial raw material, and liquid bromine is used as the bromine source. Under the catalysis of iron bromide or iron powder, bromine and benzene undergo a bromination reaction. In this reaction, bromine positive ions attack the benzene ring as an electrophilic reagent, and through the intermediate process, bromobenzene is generated. This step requires temperature control and reagent ratio to prevent the formation of polybrominates.
After obtaining bromobenzene, nitrate it. Using concentrated nitric acid and concentrated sulfuric acid as nitrifying reagents, bromobenzene reacts with nitrifying reagents at moderate temperatures to introduce nitro groups into the benzene ring. Because bromine is an ortho-para-localization group, nitro groups mainly enter the ortho and para-sites of bromine, and p-bromonitrobenzene can be obtained after separation.
Then, p-bromonitrobenzene is reduced. Using tin and hydrochloric acid or iron and hydrochloric acid system as reducing agent, nitro groups are reduced to amino groups to form p-bromoaniline. This step is violent and requires attention to temperature control.
p-bromoaniline reacts with sodium nitrite and hydrochloric acid at low temperature (0-5 ° C), and the amino group is converted into a diazo salt. The diazonium salt is extremely unstable and needs to be reacted with potassium iodide immediately. The diazonium group is replaced by an iodine atom to form p-bromoiodobenzene.
Then, the chlorination reaction is carried out. With chlorine as the chlorine source, under the action of a suitable catalyst such as ferric chloride, p-bromoiodobenzene reacts with chlorine gas, and chlorine atoms are introduced at specific positions in the benzene ring. After fine separation and purification, 1-bromo-5-iodine-2-chlorobenzene is finally obtained. Or you can try other routes, first iodine, then bromine, chlorine, according to different locator effects and reaction conditions to achieve the synthesis of the target product, but each step needs to carefully control the reaction conditions and separate impurities to obtain pure 1-bromo-5-iodine-2-chlorobenzene.
Mercury is liquid at room temperature, volatile, and its vapor is highly toxic. When storing, use a sealed container and place it in a cool and ventilated place to prevent mercury volatilization. During transportation, also ensure that the container is airtight to avoid vibration and collision and cause it to leak. If you accidentally leak, you should immediately turn on the ventilation equipment to quickly collect the scattered mercury, which can be covered with sulfur powder to promote its formation of mercury sulfide to reduce toxicity.
Lead, although solid, has many toxic compounds. Storage should be placed in a dry place to prevent it from being oxidized by moisture. The packaging must be solid to prevent damage during transportation. When handling, care should be taken to avoid lead dust flying and poisoning caused by human inhalation.
Cadmium is also highly toxic. Storage needs to isolate air and moisture to prevent chemical reactions. During transportation, relevant regulations must be strictly followed to ensure that the packaging of cadmium is intact. If cadmium compounds leak, they need to be cleaned up in time to prevent contamination of soil and water sources.
In short, mercury, lead, cadmium and other highly toxic substances in storage and transportation need to strictly follow the operating procedures and pay attention to safety protection to prevent leakage from causing environmental pollution and personal injury. A little negligence can lead to catastrophe, endangering people's lives, health and ecological balance, so be cautious.

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