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1-(Bromomethyl)-2-Chloro-4-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
660561 |
| Chemical Formula | C8H5BrClF3 |
| Molar Mass | 287.48 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Around 210 - 215 °C |
| Density | Approx. 1.7 - 1.8 g/cm³ |
| Solubility | Slightly soluble in water, soluble in organic solvents like ethanol, ether |
| Vapor Pressure | Low vapor pressure at room temperature |
| Flash Point | Around 90 - 95 °C |
| Refractive Index | Typically around 1.48 - 1.50 |
As an accredited 1-(Bromomethyl)-2-Chloro-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1-(bromomethyl)-2-chloro-4-(trifluoromethyl)benzene in sealed glass vial. |
| Storage | 1-(Bromomethyl)-2-chloro-4-(trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials. Label it clearly to prevent misidentification. This storage approach helps maintain its chemical integrity and ensures safety. |
| Shipping | 1-(Bromomethyl)-2-chloro-4-(trifluoromethyl)benzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring safe transport to prevent leakage and potential hazards. |
Competitive 1-(Bromomethyl)-2-Chloro-4-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-(Bromomethyl)-2-Chloro-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1- (bromomethyl) -2-chloro-4- (trifluoromethyl) benzene?
1 - (bromomethyl) -2 -chloro-4- (trifluoromethyl) benzene is a kind of organic compound. Its physical properties are very important, and it is related to the performance of this compound in various environments and reactions.
First of all, its appearance, under normal temperature and pressure, is often colorless to pale yellow liquid form, clear and with a certain degree of transparency. This appearance characteristic is very critical for the initial identification and observation of its state changes.
Second, its melting point and boiling point. The melting point is between -10 ° C and -5 ° C, indicating that the compound solidifies at relatively low temperatures. The boiling point is in the range of 200 ° C to 210 ° C. This property determines the temperature range at which it converts to a gaseous state during heating, and needs to be taken into account when separating and purifying.
Furthermore, density is also one of the important physical properties. Its density is about 1.6 g/cm ³, which is higher than the density of water (1 g/cm ³), so if mixed with water, the compound will settle in the bottom of the water.
In terms of solubility, this compound is insoluble in water, but it has good solubility in many organic solvents, such as ethanol, ether, and dichloromethane. This property makes it possible to select an appropriate organic solvent according to the reaction requirements in the organic synthesis reaction to promote the reaction.
Volatility, this compound has a certain degree of volatility, and in an open environment, it will slowly evaporate into the air. When operating, pay attention to ventilation conditions to avoid its accumulation in the air and cause safety hazards.
In addition, the smell of this compound also has characteristics, often with a special aromatic smell. Although it is not strongly pungent, it should be avoided for long-term inhalation.
In summary, the physical properties of 1- (bromomethyl) -2-chloro-4- (trifluoromethyl) benzene include appearance, melting point, density, solubility, volatility, and odor. All properties are interrelated and need to be carefully considered in applications in organic synthesis, chemical production, and other fields.
First of all, its appearance, under normal temperature and pressure, is often colorless to pale yellow liquid form, clear and with a certain degree of transparency. This appearance characteristic is very critical for the initial identification and observation of its state changes.
Second, its melting point and boiling point. The melting point is between -10 ° C and -5 ° C, indicating that the compound solidifies at relatively low temperatures. The boiling point is in the range of 200 ° C to 210 ° C. This property determines the temperature range at which it converts to a gaseous state during heating, and needs to be taken into account when separating and purifying.
Furthermore, density is also one of the important physical properties. Its density is about 1.6 g/cm ³, which is higher than the density of water (1 g/cm ³), so if mixed with water, the compound will settle in the bottom of the water.
In terms of solubility, this compound is insoluble in water, but it has good solubility in many organic solvents, such as ethanol, ether, and dichloromethane. This property makes it possible to select an appropriate organic solvent according to the reaction requirements in the organic synthesis reaction to promote the reaction.
Volatility, this compound has a certain degree of volatility, and in an open environment, it will slowly evaporate into the air. When operating, pay attention to ventilation conditions to avoid its accumulation in the air and cause safety hazards.
In addition, the smell of this compound also has characteristics, often with a special aromatic smell. Although it is not strongly pungent, it should be avoided for long-term inhalation.
In summary, the physical properties of 1- (bromomethyl) -2-chloro-4- (trifluoromethyl) benzene include appearance, melting point, density, solubility, volatility, and odor. All properties are interrelated and need to be carefully considered in applications in organic synthesis, chemical production, and other fields.
What are the main uses of 1- (bromomethyl) -2-chloro-4- (trifluoromethyl) benzene
1 - (bromomethyl) -2 -chloro-4- (trifluoromethyl) benzene is also an organic compound. It has a wide range of uses and plays a significant role in the field of organic synthesis.
One of them can be used as a pharmaceutical intermediate. When creating new drugs, this compound can be used as a key structural unit. Taking a class of drugs with specific physiological activities as an example, in the synthesis path, 1- (bromomethyl) -2 -chloro-4- (trifluoromethyl) benzene is linked with other organic molecules through specific chemical reactions to construct a complex drug molecular structure, which in turn imparts specific pharmacological effects to the drug, such as antibacterial, anti-inflammatory, etc.
Second, it also plays an important role in the field of pesticide synthesis. The research and development of modern pesticides pursues high efficiency, low toxicity and environmental friendliness. 1 - (bromomethyl) -2 -chloro-4 - (trifluoromethyl) benzene can be used as the starting material for the synthesis of high-efficiency pesticides. Through a series of chemical reactions, pesticide products that are highly lethal to pests, safe for crops and easily degradable in the environment can be prepared, contributing to agricultural pest control.
Third, it also has potential uses in materials science. With the development of science and technology, the demand for special performance materials is increasing. Based on this compound, through chemical modification and polymerization, new materials with unique electrical, optical or thermal properties can be prepared, such as functional materials for electronic devices, or display materials with special optical properties.
In summary, 1- (bromomethyl) -2 -chloro-4- (trifluoromethyl) benzene is a valuable organic compound in the fields of medicine, pesticides and materials science, which is of great significance to promote the development of related fields.
One of them can be used as a pharmaceutical intermediate. When creating new drugs, this compound can be used as a key structural unit. Taking a class of drugs with specific physiological activities as an example, in the synthesis path, 1- (bromomethyl) -2 -chloro-4- (trifluoromethyl) benzene is linked with other organic molecules through specific chemical reactions to construct a complex drug molecular structure, which in turn imparts specific pharmacological effects to the drug, such as antibacterial, anti-inflammatory, etc.
Second, it also plays an important role in the field of pesticide synthesis. The research and development of modern pesticides pursues high efficiency, low toxicity and environmental friendliness. 1 - (bromomethyl) -2 -chloro-4 - (trifluoromethyl) benzene can be used as the starting material for the synthesis of high-efficiency pesticides. Through a series of chemical reactions, pesticide products that are highly lethal to pests, safe for crops and easily degradable in the environment can be prepared, contributing to agricultural pest control.
Third, it also has potential uses in materials science. With the development of science and technology, the demand for special performance materials is increasing. Based on this compound, through chemical modification and polymerization, new materials with unique electrical, optical or thermal properties can be prepared, such as functional materials for electronic devices, or display materials with special optical properties.
In summary, 1- (bromomethyl) -2 -chloro-4- (trifluoromethyl) benzene is a valuable organic compound in the fields of medicine, pesticides and materials science, which is of great significance to promote the development of related fields.
What are the synthesis methods of 1- (bromomethyl) -2-chloro-4- (trifluoromethyl) benzene
There are many ways to synthesize 1 - (bromomethyl) -2 -chloro-4- (trifluoromethyl) benzene. First, aromatics containing corresponding substituents can be started. First, aromatics with chlorine and trifluoromethyl are heated and refluxed in a suitable solvent, such as carbon tetrachloride, with appropriate brominating reagents, such as N-bromosuccinimide (NBS) and initiators such as benzoyl peroxide (BPO). In this process, NBS provides the bromine source, and BPO initiates a free radical reaction, which prompts the hydrogen of the methyl side chain of the aromatic hydrocarbon to be replaced by bromine, resulting in the target product.
Furthermore, halogenated benzyl derivatives can also be used as raw materials. The halogenated benzyl containing chlorine and trifluoromethyl is selected to react in a polar aprotic solvent such as dimethylformamide (DMF) with an appropriate nucleophilic reagent, such as brominated salts. The halogen atom of halogenated benzyl is replaced by a bromide ion nucleophilic. After this step, 1- (bromomethyl) -2 -chloro-4- (trifluoromethyl) benzene can also be obtained.
Another way is to build the basic skeleton of the benzene ring first, and then gradually introduce chlorine, trifluoromethyl and bromomethyl. With a suitable substituted benzene derivative as the starting material, the desired functional groups are introduced in sequence through multi-step reactions, such as electrophilic substitution, nucleophilic substitution, etc. Although this strategy is a little complicated, it is also an effective synthesis method under certain specific conditions. Each method has its own advantages and disadvantages. In practical application, it is necessary to comprehensively consider many factors such as the availability of raw materials, the difficulty of controlling reaction conditions, and the purity requirements of the target product.
Furthermore, halogenated benzyl derivatives can also be used as raw materials. The halogenated benzyl containing chlorine and trifluoromethyl is selected to react in a polar aprotic solvent such as dimethylformamide (DMF) with an appropriate nucleophilic reagent, such as brominated salts. The halogen atom of halogenated benzyl is replaced by a bromide ion nucleophilic. After this step, 1- (bromomethyl) -2 -chloro-4- (trifluoromethyl) benzene can also be obtained.
Another way is to build the basic skeleton of the benzene ring first, and then gradually introduce chlorine, trifluoromethyl and bromomethyl. With a suitable substituted benzene derivative as the starting material, the desired functional groups are introduced in sequence through multi-step reactions, such as electrophilic substitution, nucleophilic substitution, etc. Although this strategy is a little complicated, it is also an effective synthesis method under certain specific conditions. Each method has its own advantages and disadvantages. In practical application, it is necessary to comprehensively consider many factors such as the availability of raw materials, the difficulty of controlling reaction conditions, and the purity requirements of the target product.
What are the precautions for 1- (bromomethyl) -2-chloro-4- (trifluoromethyl) benzene during storage and transportation?
1 - (bromomethyl) - 2 - chloro - 4 - (trifluoromethyl) benzene is one of the organic compounds. During storage and transportation, many matters need to be paid attention to.
First words storage. This material is active in nature and should be placed in a cool, dry and well ventilated place. Because it is more sensitive to heat, if the ambient temperature is too high, it may decompose or other chemical reactions occur, so it must be kept away from heat and fire sources. And should be stored separately from oxidizing agents, strong bases and other substances, because it is easy to react with these substances and cause danger. Furthermore, the storage place should be equipped with suitable equipment for containing and handling leaks in case of leakage, so that it can be responded to in time.
As for transportation, it should not be neglected. Be sure to ensure that the packaging is complete and well sealed to prevent the packaging from being damaged due to vibration and collision during transportation, which may cause leakage. During transportation, it is necessary to avoid contact with water, because it may react with water and produce harmful gases or other adverse consequences. Transportation vehicles should also be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment for safety. Transport personnel should also be familiar with the characteristics of the chemical and emergency treatment methods. In case of emergencies, they can be properly disposed of in time. In conclusion, all aspects of the storage and transportation of 1 - (bromomethyl) - 2 - chloro - 4 - (trifluoromethyl) benzene need to be handled with caution to ensure safety.
First words storage. This material is active in nature and should be placed in a cool, dry and well ventilated place. Because it is more sensitive to heat, if the ambient temperature is too high, it may decompose or other chemical reactions occur, so it must be kept away from heat and fire sources. And should be stored separately from oxidizing agents, strong bases and other substances, because it is easy to react with these substances and cause danger. Furthermore, the storage place should be equipped with suitable equipment for containing and handling leaks in case of leakage, so that it can be responded to in time.
As for transportation, it should not be neglected. Be sure to ensure that the packaging is complete and well sealed to prevent the packaging from being damaged due to vibration and collision during transportation, which may cause leakage. During transportation, it is necessary to avoid contact with water, because it may react with water and produce harmful gases or other adverse consequences. Transportation vehicles should also be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment for safety. Transport personnel should also be familiar with the characteristics of the chemical and emergency treatment methods. In case of emergencies, they can be properly disposed of in time. In conclusion, all aspects of the storage and transportation of 1 - (bromomethyl) - 2 - chloro - 4 - (trifluoromethyl) benzene need to be handled with caution to ensure safety.
What are the effects of 1- (bromomethyl) -2-chloro-4- (trifluoromethyl) benzene on the environment and human health?
1 - (bromomethyl) -2 -chloro-4- (trifluoromethyl) benzene is also an organic compound. Its impact on the environment and human health cannot be ignored.
In the environment, this compound may be quite stable and not easy to degrade. It enters natural water and soil, or causes environmental pollution. If it flows into rivers, lakes and seas, or is ingested by aquatic organisms, it accumulates through the food chain and affects the ecological balance. In the soil, it may change the structure and function of soil microbial community, which in turn affects plant growth and development.
As for human health, this compound may enter the human body through respiration, skin contact, dietary intake, etc. If inhaling its volatile gaseous substances, or irritating the respiratory tract, causing cough, asthma and other symptoms. Through skin contact, or cause skin allergies, inflammation. If you eat food containing this compound by mistake, or damage the digestive system, cause nausea, vomiting, abdominal pain, etc. And this substance may be potentially carcinogenic and teratogenic, long-term exposure to it, or increase the risk of cancer, affecting the normal development of the fetus.
In summary, 1- (bromomethyl) -2-chloro-4- (trifluoromethyl) benzene has potential hazards to the environment and human health. It should be treated with caution and strengthened control and monitoring to reduce its adverse effects.
In the environment, this compound may be quite stable and not easy to degrade. It enters natural water and soil, or causes environmental pollution. If it flows into rivers, lakes and seas, or is ingested by aquatic organisms, it accumulates through the food chain and affects the ecological balance. In the soil, it may change the structure and function of soil microbial community, which in turn affects plant growth and development.
As for human health, this compound may enter the human body through respiration, skin contact, dietary intake, etc. If inhaling its volatile gaseous substances, or irritating the respiratory tract, causing cough, asthma and other symptoms. Through skin contact, or cause skin allergies, inflammation. If you eat food containing this compound by mistake, or damage the digestive system, cause nausea, vomiting, abdominal pain, etc. And this substance may be potentially carcinogenic and teratogenic, long-term exposure to it, or increase the risk of cancer, affecting the normal development of the fetus.
In summary, 1- (bromomethyl) -2-chloro-4- (trifluoromethyl) benzene has potential hazards to the environment and human health. It should be treated with caution and strengthened control and monitoring to reduce its adverse effects.
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