Linshang Chemical
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1-(Bromomethyl)-3-Chloro-5-Fluorobenzene
Linshang Chemical
|
HS Code |
608479 |
| Chemical Formula | C7H5BrClF |
| Molecular Weight | 223.47 |
| Appearance | Typically a colorless to light - colored liquid |
| Boiling Point | Data may vary, but in the range of relatively high boiling points due to halogen substitution |
| Density | Expected to be higher than water due to halogen atoms |
| Solubility In Water | Low solubility, as it is an organic halogen - containing compound |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Reactivity | Reactive due to the presence of bromomethyl group, can undergo substitution reactions |
As an accredited 1-(Bromomethyl)-3-Chloro-5-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1-(bromomethyl)-3 - chloro - 5 - fluorobenzene in a sealed, labeled chemical bottle. |
| Storage | 1-(Bromomethyl)-3-chloro-5-fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage. Since it is a potentially hazardous chemical, store it separately from incompatible substances, such as oxidizing agents and reactive metals, to avoid dangerous reactions. |
| Shipping | 1-(Bromomethyl)-3 -chloro -5 -fluorobenzene is a chemical. Shipments must comply with regulations for hazardous chemicals. It should be properly packaged in suitable containers, labeled clearly, and transported by approved carriers following safety protocols. |
Competitive 1-(Bromomethyl)-3-Chloro-5-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
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What are the main uses of 1- (bromomethyl) -3-chloro-5-fluorobenzene?
(Note: The following answer is in the style of ancient classical Chinese, as close as possible to the expression of "Tiangong Kaiwu")
Fu 1- (cyanomethyl) -3-bromo-5-bromopyridine, which is a substance of organic chemistry. It has a wide range of uses and has important effects in various fields.
First, in the process of pharmaceutical synthesis, this substance can be a key intermediate. To cover the creation of medicine, it is necessary to carefully construct the molecular structure. The unique structure of 1- (cyanomethyl) -3-bromo-5-bromopyridine allows pharmacists to introduce specific functional groups and then build compounds with specific pharmacological activities. If you want to develop a specific drug for a certain type of disease, you can use this substance to open a synthesis path, and through multi-step reactions, you can finally obtain the desired active ingredient.
Second, in the field of materials science, it can also play a role. In the research and development of new organic materials, it can be used as a basic raw material to participate in the reaction. Through specific chemical reaction conditions, it is combined with other materials to endow the material with novel physical and chemical properties. Such as improving the conductivity and optical properties of the material, making the material suitable for cutting-edge scientific and technological fields such as photoelectric displays and sensors.
Third, in the study of organic synthetic chemistry, 1- (cyanomethyl) -3-bromo-5-bromopyridine is an important block. Chemists can use this to expand the molecular skeleton and explore novel reaction pathways and synthesis strategies. By changing the reaction substrates, reaction conditions and other factors, complex and diverse organic compounds are created, which contribute to the theoretical development and practical innovation of organic chemistry.
In summary, although 1- (cyanomethyl) -3-bromo-5-bromopyridine is a microscopic chemical substance, it has important uses that cannot be ignored in the broad fields of medicine, materials, and chemical research, and promotes the progress and development of various fields.
Fu 1- (cyanomethyl) -3-bromo-5-bromopyridine, which is a substance of organic chemistry. It has a wide range of uses and has important effects in various fields.
First, in the process of pharmaceutical synthesis, this substance can be a key intermediate. To cover the creation of medicine, it is necessary to carefully construct the molecular structure. The unique structure of 1- (cyanomethyl) -3-bromo-5-bromopyridine allows pharmacists to introduce specific functional groups and then build compounds with specific pharmacological activities. If you want to develop a specific drug for a certain type of disease, you can use this substance to open a synthesis path, and through multi-step reactions, you can finally obtain the desired active ingredient.
Second, in the field of materials science, it can also play a role. In the research and development of new organic materials, it can be used as a basic raw material to participate in the reaction. Through specific chemical reaction conditions, it is combined with other materials to endow the material with novel physical and chemical properties. Such as improving the conductivity and optical properties of the material, making the material suitable for cutting-edge scientific and technological fields such as photoelectric displays and sensors.
Third, in the study of organic synthetic chemistry, 1- (cyanomethyl) -3-bromo-5-bromopyridine is an important block. Chemists can use this to expand the molecular skeleton and explore novel reaction pathways and synthesis strategies. By changing the reaction substrates, reaction conditions and other factors, complex and diverse organic compounds are created, which contribute to the theoretical development and practical innovation of organic chemistry.
In summary, although 1- (cyanomethyl) -3-bromo-5-bromopyridine is a microscopic chemical substance, it has important uses that cannot be ignored in the broad fields of medicine, materials, and chemical research, and promotes the progress and development of various fields.
What are the physical properties of 1- (bromomethyl) -3-chloro-5-fluorobenzene?
(Cyanomethyl) -3-bromo-5-fluoropyridine is an important compound in the field of organic synthesis. Its unique physical properties have a profound impact on the process and product characteristics of organic synthesis reactions.
This compound is mostly solid at room temperature, with good crystalline morphology and regular and ordered crystal structure, which lays the foundation for its stability. Its melting point is in a specific range, and the exact value varies depending on purity and measurement conditions, roughly within a certain range. The existence of the melting point makes the compound transition from solid state to liquid state smoothly during heating, providing conditions for many reactions that require specific states to participate.
In terms of solubility, (cyanomethyl) -3-bromo-5-fluoropyridine exhibits a certain solubility in common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF). In dichloromethane, by virtue of the interaction between the two molecules, the compound can be uniformly dispersed to form a homogeneous solution, which is conducive to fully participating in the reaction in the reaction system using dichloromethane as the solvent. In DMF, its solubility is also good, and the strong polarity of DMF can form an effective interaction with (cyanomethyl) -3-bromo-5-fluoropyridine molecules, which promotes the smooth dissolution process.
Its density is also one of the important physical properties. The density reflects the mass per unit volume of the substance, and the specific density value determines its location and distribution in the mixed system. For example, in a liquid-liquid reaction system, the difference between its density and that of other liquids will affect the reaction interface and mass transfer process.
In addition, the compound has a certain degree of volatility. Although the volatility is relatively low, some molecules will escape the system at specific temperatures and environmental conditions. This property needs to be taken into account during storage and reaction operations to prevent compound loss due to volatilization or impact on the environment.
In summary, the physical properties of (cyanomethyl) -3-bromo-5-fluoropyridine, including melting point, solubility, density, and volatility, are interrelated and interact together, and play a key role in organic synthesis, storage, and related operations, which profoundly affect its practical application.
This compound is mostly solid at room temperature, with good crystalline morphology and regular and ordered crystal structure, which lays the foundation for its stability. Its melting point is in a specific range, and the exact value varies depending on purity and measurement conditions, roughly within a certain range. The existence of the melting point makes the compound transition from solid state to liquid state smoothly during heating, providing conditions for many reactions that require specific states to participate.
In terms of solubility, (cyanomethyl) -3-bromo-5-fluoropyridine exhibits a certain solubility in common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF). In dichloromethane, by virtue of the interaction between the two molecules, the compound can be uniformly dispersed to form a homogeneous solution, which is conducive to fully participating in the reaction in the reaction system using dichloromethane as the solvent. In DMF, its solubility is also good, and the strong polarity of DMF can form an effective interaction with (cyanomethyl) -3-bromo-5-fluoropyridine molecules, which promotes the smooth dissolution process.
Its density is also one of the important physical properties. The density reflects the mass per unit volume of the substance, and the specific density value determines its location and distribution in the mixed system. For example, in a liquid-liquid reaction system, the difference between its density and that of other liquids will affect the reaction interface and mass transfer process.
In addition, the compound has a certain degree of volatility. Although the volatility is relatively low, some molecules will escape the system at specific temperatures and environmental conditions. This property needs to be taken into account during storage and reaction operations to prevent compound loss due to volatilization or impact on the environment.
In summary, the physical properties of (cyanomethyl) -3-bromo-5-fluoropyridine, including melting point, solubility, density, and volatility, are interrelated and interact together, and play a key role in organic synthesis, storage, and related operations, which profoundly affect its practical application.
What is the chemical synthesis method of 1- (bromomethyl) -3-chloro-5-fluorobenzene?
To prepare 1 - (hydroxymethyl) - 3 - bromo - 5 - chlorobenzene, the following method can be followed.
First take the corresponding benzene derivative as the starting material. Under suitable reaction conditions, a specific substitution reaction of the benzene ring is carried out to introduce hydroxymethyl groups. This process may require the selection of specific reagents and catalysts, such as formaldehyde and a certain reagent. Under a specific temperature, pressure and catalyst environment, an electrophilic substitution reaction can occur at a specific position on the benzene ring to access hydroxymethyl groups to form a benzene intermediate containing hydroxymethyl groups.
Then, for this intermediate, a bromination reaction is carried out. Bromine is often used as the bromine source, with appropriate catalysts, such as iron or iron salt catalysts. In a suitable reaction solvent, control the reaction temperature and time, so that bromine atoms selectively replace hydrogen atoms at the target position on the benzene ring, thereby introducing bromine atoms to obtain benzene derivative intermediates containing hydroxymethyl and bromine atoms.
In the last step, the resulting intermediate is chlorinated. Under suitable reaction conditions, such as the presence of a specific catalyst and a specific temperature and reaction atmosphere, the chlorine atom replaces the hydrogen atom at the desired position on the benzene ring to achieve the synthesis of 1- (hydroxymethyl) -3-bromo-5-chlorobenzene.
After each step of the reaction, it is necessary to separate and purify the intermediate and final product by means of distillation, recrystallization, column chromatography, etc., to ensure the purity of the product in each step of the reaction, so as to facilitate the subsequent reaction and the quality of the final product. And the conditions of each step of the reaction need to be carefully adjusted to achieve the best reaction yield and selectivity.
First take the corresponding benzene derivative as the starting material. Under suitable reaction conditions, a specific substitution reaction of the benzene ring is carried out to introduce hydroxymethyl groups. This process may require the selection of specific reagents and catalysts, such as formaldehyde and a certain reagent. Under a specific temperature, pressure and catalyst environment, an electrophilic substitution reaction can occur at a specific position on the benzene ring to access hydroxymethyl groups to form a benzene intermediate containing hydroxymethyl groups.
Then, for this intermediate, a bromination reaction is carried out. Bromine is often used as the bromine source, with appropriate catalysts, such as iron or iron salt catalysts. In a suitable reaction solvent, control the reaction temperature and time, so that bromine atoms selectively replace hydrogen atoms at the target position on the benzene ring, thereby introducing bromine atoms to obtain benzene derivative intermediates containing hydroxymethyl and bromine atoms.
In the last step, the resulting intermediate is chlorinated. Under suitable reaction conditions, such as the presence of a specific catalyst and a specific temperature and reaction atmosphere, the chlorine atom replaces the hydrogen atom at the desired position on the benzene ring to achieve the synthesis of 1- (hydroxymethyl) -3-bromo-5-chlorobenzene.
After each step of the reaction, it is necessary to separate and purify the intermediate and final product by means of distillation, recrystallization, column chromatography, etc., to ensure the purity of the product in each step of the reaction, so as to facilitate the subsequent reaction and the quality of the final product. And the conditions of each step of the reaction need to be carefully adjusted to achieve the best reaction yield and selectivity.
What are the precautions for storing and transporting 1- (bromomethyl) -3-chloro-5-fluorobenzene?
Ether groups, amino groups, alkanes, and alkenyne are really important to pay attention to during storage and transportation.
Ether groups are prone to peroxides, which is a serious problem. Therefore, when storing, it should be placed in a cool, ventilated and dark place, and must not be near fire and hot topics to prevent peroxides from being decomposed by heat and causing the danger of explosion. And it is necessary to regularly test the content of peroxides. If the content is too high, it must be properly handled to remove its hidden dangers. During transportation, it should also be stable to prevent its shock and collision, causing damage to the container and material leakage.
Amino groups are mostly alkaline, and some are corrosive and toxic. A well-sealed container should be selected for storage to prevent it from reacting with acidic gases such as carbon dioxide in the air and deteriorating. At the same time, it should be placed separately from acidic substances to avoid their interaction and cause danger. When transporting, the vehicles and containers used must have anti-corrosion measures, and the escorts should be familiar with their characteristics and emergency disposal methods.
Alkane substances, many of which are flammable and have a low ignition point. Fireworks are strictly prohibited in the place of storage, and there must be perfect fire and explosion-proof facilities. Electrical equipment in the warehouse should also be explosion-proof. During transportation, the tanks and other containers used should be well grounded to prevent static electricity accumulation from causing fires.
Alkynes, due to their unsaturated bonds, are chemically active and prone to reactions such as addition and polymerization. Storage should be at low temperature, protected from light, and stored separately from oxidants, strong acids, strong bases, etc., to prevent violent reactions. When transporting, ensure that the container is tight, and take measures such as cooling to ensure its stability.
In short, when storing and transporting these things, they should be stored and transported according to their characteristics, strictly abide by specifications, and operate cautiously to ensure safety.
Ether groups are prone to peroxides, which is a serious problem. Therefore, when storing, it should be placed in a cool, ventilated and dark place, and must not be near fire and hot topics to prevent peroxides from being decomposed by heat and causing the danger of explosion. And it is necessary to regularly test the content of peroxides. If the content is too high, it must be properly handled to remove its hidden dangers. During transportation, it should also be stable to prevent its shock and collision, causing damage to the container and material leakage.
Amino groups are mostly alkaline, and some are corrosive and toxic. A well-sealed container should be selected for storage to prevent it from reacting with acidic gases such as carbon dioxide in the air and deteriorating. At the same time, it should be placed separately from acidic substances to avoid their interaction and cause danger. When transporting, the vehicles and containers used must have anti-corrosion measures, and the escorts should be familiar with their characteristics and emergency disposal methods.
Alkane substances, many of which are flammable and have a low ignition point. Fireworks are strictly prohibited in the place of storage, and there must be perfect fire and explosion-proof facilities. Electrical equipment in the warehouse should also be explosion-proof. During transportation, the tanks and other containers used should be well grounded to prevent static electricity accumulation from causing fires.
Alkynes, due to their unsaturated bonds, are chemically active and prone to reactions such as addition and polymerization. Storage should be at low temperature, protected from light, and stored separately from oxidants, strong acids, strong bases, etc., to prevent violent reactions. When transporting, ensure that the container is tight, and take measures such as cooling to ensure its stability.
In short, when storing and transporting these things, they should be stored and transported according to their characteristics, strictly abide by specifications, and operate cautiously to ensure safety.
What are the effects of 1- (bromomethyl) -3-chloro-5-fluorobenzene on the environment and human health?
(1) Methyl groups are active in nature and have a lot to do with chemical industry. However, if this thing escapes in the environment, its harm is very shallow.
Methyl groups enter the natural environment, or sewage soil, or stain the air. Soil and water are polluted, which is also the resistance of vegetation. Plants depend on water and soil for nourishment, and methyl groups disturb them, so that the root absorption and plant development are chaotic. The leaves of the light are wilted, and the vitality of the heavy is gone. And the ecological balance of water and soil is also broken, and the genus of insects and microorganisms are all affected by it. The ecological chain is interlocked, and the whole chain is damaged in one place.
As for the air, methyl is scattered, and the smell is pungent. People smell it, and the respiratory tract bears the brunt. Light cases cause cough and asthma, severe cases damage the ability of the lungs, and the disease of breathing occurs. Long-term exposure to methyl-containing air, there is a risk of cancer, and the damage to the viscera should not be underestimated.
(2) Tribromine is colorful and strong. In the environment, its diffusion is also fast, and it can reach water bodies, soil, and atmosphere.
When it enters the water body, the qualitative change of water. The water on which aquatic organisms depend for survival is polluted, and the genera of fish, turtles, shrimp, and crabs may die in the present or remain in the future. Its reproduction and reproduction are hindered, and the continuation of the population is worrying. And water is the source of life. People drink this sewage, and gastrointestinal diseases, liver and kidney damage, gradually emerge.
In the soil, tribromine is accumulated, the fertility of the soil is reduced, and the structure is changed. Cultivated crops, the yield decreases and the quality is poor. The activity of microorganisms in the soil is suppressed, and the soil is self-purifying and weak, and a vicious cycle begins.
(3) Pentachlorophenol has been used for anti-corrosion and insect control. However, its harm to the environment and human body is obvious.
In the environment, Pentachlorophenol is difficult to degrade, and it will not accumulate for a long time. In the soil, it is compacted, and the ability to ventilate and permeate water is lost. In water bodies, algae and other plankton are poisoned by it, and the foundation of aquatic ecology is shaken.
Personal exposure to PCP causes skin allergies and inflammation. If eaten or inhaled by mistake, the nervous, immune and other systems are attacked. Children are especially affected, with stunted growth and development, and the development of their mental body can be affected by it. And this thing has the risk of carcinogenesis and teratogenesis, and the continuation of the family is also clouded.
To sum up, the harm of methyl, tribromo, and pentachlorophenol to the environment and people is deep and huge. Be careful to prevent its escape and protect the environment and human safety.
Methyl groups enter the natural environment, or sewage soil, or stain the air. Soil and water are polluted, which is also the resistance of vegetation. Plants depend on water and soil for nourishment, and methyl groups disturb them, so that the root absorption and plant development are chaotic. The leaves of the light are wilted, and the vitality of the heavy is gone. And the ecological balance of water and soil is also broken, and the genus of insects and microorganisms are all affected by it. The ecological chain is interlocked, and the whole chain is damaged in one place.
As for the air, methyl is scattered, and the smell is pungent. People smell it, and the respiratory tract bears the brunt. Light cases cause cough and asthma, severe cases damage the ability of the lungs, and the disease of breathing occurs. Long-term exposure to methyl-containing air, there is a risk of cancer, and the damage to the viscera should not be underestimated.
(2) Tribromine is colorful and strong. In the environment, its diffusion is also fast, and it can reach water bodies, soil, and atmosphere.
When it enters the water body, the qualitative change of water. The water on which aquatic organisms depend for survival is polluted, and the genera of fish, turtles, shrimp, and crabs may die in the present or remain in the future. Its reproduction and reproduction are hindered, and the continuation of the population is worrying. And water is the source of life. People drink this sewage, and gastrointestinal diseases, liver and kidney damage, gradually emerge.
In the soil, tribromine is accumulated, the fertility of the soil is reduced, and the structure is changed. Cultivated crops, the yield decreases and the quality is poor. The activity of microorganisms in the soil is suppressed, and the soil is self-purifying and weak, and a vicious cycle begins.
(3) Pentachlorophenol has been used for anti-corrosion and insect control. However, its harm to the environment and human body is obvious.
In the environment, Pentachlorophenol is difficult to degrade, and it will not accumulate for a long time. In the soil, it is compacted, and the ability to ventilate and permeate water is lost. In water bodies, algae and other plankton are poisoned by it, and the foundation of aquatic ecology is shaken.
Personal exposure to PCP causes skin allergies and inflammation. If eaten or inhaled by mistake, the nervous, immune and other systems are attacked. Children are especially affected, with stunted growth and development, and the development of their mental body can be affected by it. And this thing has the risk of carcinogenesis and teratogenesis, and the continuation of the family is also clouded.
To sum up, the harm of methyl, tribromo, and pentachlorophenol to the environment and people is deep and huge. Be careful to prevent its escape and protect the environment and human safety.
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