Linshang Chemical
PRODUCTS
1-Chloro-2,3,4-Trifluorobenzene
Linshang Chemical
|
HS Code |
279718 |
| Chemical Formula | C6H2ClF3 |
| Molar Mass | 166.53 g/mol |
| Appearance | Colorless liquid |
| Boiling Point | 126 - 128 °C |
| Density | 1.439 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents |
| Flash Point | 32 °C |
| Odor | Characteristic aromatic odor |
As an accredited 1-Chloro-2,3,4-Trifluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 2,3,4 - trifluorobenzene: Packed in 5 - liter containers for chemical storage. |
| Storage | 1 - Chloro - 2,3,4 - trifluorobenzene should be stored in a cool, well - ventilated area away from sources of ignition. Keep it in a tightly closed container made of compatible materials, like steel or certain plastics, to prevent leakage. Store it separate from oxidizing agents, bases, and reactive chemicals to avoid potential reactions. |
| Shipping | 1 - Chloro - 2,3,4 - trifluorobenzene, a chemical, should be shipped in tightly sealed, corrosion - resistant containers. Label as hazardous due to its chemical nature, and follow all regulations for transporting such substances. |
Competitive 1-Chloro-2,3,4-Trifluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Chloro-2,3,4-Trifluorobenzene in China?
As a trusted 1-Chloro-2,3,4-Trifluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Chloro-2,3,4-Trifluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-chloro-2,3,4-trifluorobenzene?
1-Chloro-2,3,4-trifluorobenzene is also an organic compound. It has a wide range of main uses and is used in many fields.
First, it is often a key intermediate in the synthesis of medicine. The development of medicine is like building a delicate castle, and every step needs to be precise. With its unique chemical structure, 1-chloro-2,3,4-trifluorobenzene can participate in many reactions, contributing to the construction of complex drug molecular skeletons. Through specific chemical reactions, it can be ingeniously integrated into drug molecules, giving drugs unique activity and function, or enhancing the affinity of drugs to specific targets, or improving the metabolic characteristics of drugs, helping to create new drugs, and contributing to human health.
Second, in the field of pesticides, it also plays an important role. The efficacy of pesticides is related to the growth and harvest of crops. 1-Chloro-2,3,4-trifluorobenzene can be used as an important raw material for the synthesis of highly efficient and low-toxic pesticides. After a series of chemical transformations, pesticide products targeting specific pests or diseases can be prepared. Such pesticides may have a unique mechanism of action, which can precisely attack pests, while reducing the negative impact on the environment, in line with the current needs of green agriculture development, to ensure the quality and safety of agricultural products.
Furthermore, in the field of materials science, it also has applications. With the advancement of science and technology, the demand for new materials is increasing day by day. 1-chloro-2,3,4-trifluorobenzene can participate in the synthesis process of polymer materials. By polymerizing with other monomers, polymers with special properties are formed. Such polymers may have good heat resistance and chemical corrosion resistance, and can be applied to high-end fields such as electronics and aerospace to meet the strict requirements of material properties in different industries.
In summary, although 1-chloro-2,3,4-trifluorobenzene is an organic compound, it plays an indispensable role in the fields of medicine, pesticides, and materials science, promoting the development and progress of various industries.
First, it is often a key intermediate in the synthesis of medicine. The development of medicine is like building a delicate castle, and every step needs to be precise. With its unique chemical structure, 1-chloro-2,3,4-trifluorobenzene can participate in many reactions, contributing to the construction of complex drug molecular skeletons. Through specific chemical reactions, it can be ingeniously integrated into drug molecules, giving drugs unique activity and function, or enhancing the affinity of drugs to specific targets, or improving the metabolic characteristics of drugs, helping to create new drugs, and contributing to human health.
Second, in the field of pesticides, it also plays an important role. The efficacy of pesticides is related to the growth and harvest of crops. 1-Chloro-2,3,4-trifluorobenzene can be used as an important raw material for the synthesis of highly efficient and low-toxic pesticides. After a series of chemical transformations, pesticide products targeting specific pests or diseases can be prepared. Such pesticides may have a unique mechanism of action, which can precisely attack pests, while reducing the negative impact on the environment, in line with the current needs of green agriculture development, to ensure the quality and safety of agricultural products.
Furthermore, in the field of materials science, it also has applications. With the advancement of science and technology, the demand for new materials is increasing day by day. 1-chloro-2,3,4-trifluorobenzene can participate in the synthesis process of polymer materials. By polymerizing with other monomers, polymers with special properties are formed. Such polymers may have good heat resistance and chemical corrosion resistance, and can be applied to high-end fields such as electronics and aerospace to meet the strict requirements of material properties in different industries.
In summary, although 1-chloro-2,3,4-trifluorobenzene is an organic compound, it plays an indispensable role in the fields of medicine, pesticides, and materials science, promoting the development and progress of various industries.
What are the physical properties of 1-chloro-2,3,4-trifluorobenzene?
1-Chloro-2,3,4-trifluorobenzene is one of the organic compounds. It has unique physical properties, which are described below.
First of all, under normal temperature and pressure, 1-chloro-2,3,4-trifluorobenzene is a colorless and transparent liquid. It is clear in appearance and has no obvious impurities.
As for its boiling point, it is about 140-142 ° C. When the temperature gradually rises, the compound gradually changes from liquid to gaseous state. This boiling point characteristic is crucial in the chemical operation of separation and purification.
In terms of melting point, the melting point of 1-chloro-2,3,4-trifluorobenzene is about -35 ° C. When the temperature drops to this temperature, the compound solidifies from liquid to solid. This property needs to be taken into account during storage and transportation.
Its density is about 1.46 g/cm ³, which is heavier than water. If mixed with water, it will sink underwater.
1-chloro-2,3,4-trifluorobenzene has little solubility in water and is insoluble in water. However, in organic solvents such as ethanol, ether, acetone, etc., it exhibits good solubility and can be miscible with various organic solvents in any ratio.
In addition, the compound has a certain degree of volatility, which can evaporate slowly in the air, and its vapor is heavier than the air, which is easy to accumulate in low places. And it has a pungent smell, and it can be felt obviously when smelled. It has a certain irritating effect on the human respiratory tract and mucosal parts such as eyes and nose.
The above are all the main physical properties of 1-chloro-2,3,4-trifluorobenzene. In the fields of chemical production, scientific research experiments, etc., you can be handy and use it well.
First of all, under normal temperature and pressure, 1-chloro-2,3,4-trifluorobenzene is a colorless and transparent liquid. It is clear in appearance and has no obvious impurities.
As for its boiling point, it is about 140-142 ° C. When the temperature gradually rises, the compound gradually changes from liquid to gaseous state. This boiling point characteristic is crucial in the chemical operation of separation and purification.
In terms of melting point, the melting point of 1-chloro-2,3,4-trifluorobenzene is about -35 ° C. When the temperature drops to this temperature, the compound solidifies from liquid to solid. This property needs to be taken into account during storage and transportation.
Its density is about 1.46 g/cm ³, which is heavier than water. If mixed with water, it will sink underwater.
1-chloro-2,3,4-trifluorobenzene has little solubility in water and is insoluble in water. However, in organic solvents such as ethanol, ether, acetone, etc., it exhibits good solubility and can be miscible with various organic solvents in any ratio.
In addition, the compound has a certain degree of volatility, which can evaporate slowly in the air, and its vapor is heavier than the air, which is easy to accumulate in low places. And it has a pungent smell, and it can be felt obviously when smelled. It has a certain irritating effect on the human respiratory tract and mucosal parts such as eyes and nose.
The above are all the main physical properties of 1-chloro-2,3,4-trifluorobenzene. In the fields of chemical production, scientific research experiments, etc., you can be handy and use it well.
Is 1-chloro-2,3,4-trifluorobenzene chemically stable?
The chemical stability of 1-chloro-2,3,4-trifluorobenzene depends on many factors and varies under different situations.
Looking at its structure, the benzene ring is inherently stable, but the chlorine atoms and trifluorine atoms connected to the ring have a great impact on its chemical properties. Fluorine atoms have extremely strong electronegativity, which can reduce the electron cloud density of the benzene ring, make the benzene ring more vulnerable to attack by electrophilic reagents, and at the same time, enhance the stability of the C-F bond in the molecule. Although the electronegativity of chlorine atoms is slightly weaker than that of fluorine atoms, it can also affect the distribution of electron clouds in the benzene ring.
Under normal conditions, 1-chloro-2,3,4-trifluorobenzene is quite stable. The chemical bond energy in its molecule is relatively high, and specific conditions are required to initiate a reaction. If you want to make it undergo nucleophilic substitution, you usually need more severe conditions, such as high temperature, strong alkali, etc. Due to the decrease in the electron cloud density of the benzene ring, it is more difficult for nucleophilic reagents to attack.
However, under certain conditions, its stability will also change. In case of strong oxidizing agents, although the structure of the benzene ring is relatively stable, its side chains or substituents may be oxidized. In addition, under the initiation conditions such as light or high temperature, the C-Cl bond or C-F bond may also be homogenized, which may initiate a series of free radical reactions.
Re-examine its reactivity with other reagents. In organic synthesis, due to the change of electron cloud density of benzene ring, the activity of electrophilic substitution reaction decreases, and the substitution position is also affected by the localization effect of fluorine and chlorine atoms. However, when there is a suitable catalyst, the reaction path and activation energy can be changed, so that the reaction that was difficult to occur can be carried out.
Overall, 1-chloro-2,3,4-trifluorobenzene is chemically stable under conventional conditions, but under specific conditions, due to the atomic properties and interactions in the molecular structure, it will exhibit different reactivity and stability changes.
Looking at its structure, the benzene ring is inherently stable, but the chlorine atoms and trifluorine atoms connected to the ring have a great impact on its chemical properties. Fluorine atoms have extremely strong electronegativity, which can reduce the electron cloud density of the benzene ring, make the benzene ring more vulnerable to attack by electrophilic reagents, and at the same time, enhance the stability of the C-F bond in the molecule. Although the electronegativity of chlorine atoms is slightly weaker than that of fluorine atoms, it can also affect the distribution of electron clouds in the benzene ring.
Under normal conditions, 1-chloro-2,3,4-trifluorobenzene is quite stable. The chemical bond energy in its molecule is relatively high, and specific conditions are required to initiate a reaction. If you want to make it undergo nucleophilic substitution, you usually need more severe conditions, such as high temperature, strong alkali, etc. Due to the decrease in the electron cloud density of the benzene ring, it is more difficult for nucleophilic reagents to attack.
However, under certain conditions, its stability will also change. In case of strong oxidizing agents, although the structure of the benzene ring is relatively stable, its side chains or substituents may be oxidized. In addition, under the initiation conditions such as light or high temperature, the C-Cl bond or C-F bond may also be homogenized, which may initiate a series of free radical reactions.
Re-examine its reactivity with other reagents. In organic synthesis, due to the change of electron cloud density of benzene ring, the activity of electrophilic substitution reaction decreases, and the substitution position is also affected by the localization effect of fluorine and chlorine atoms. However, when there is a suitable catalyst, the reaction path and activation energy can be changed, so that the reaction that was difficult to occur can be carried out.
Overall, 1-chloro-2,3,4-trifluorobenzene is chemically stable under conventional conditions, but under specific conditions, due to the atomic properties and interactions in the molecular structure, it will exhibit different reactivity and stability changes.
What are the synthesis methods of 1-chloro-2,3,4-trifluorobenzene?
The common methods for synthesizing 1-chloro-2,3,4-trifluorobenzene are as follows.
One is the halogenation reaction path. Using a suitable benzene derivative as the starting material, chlorine atoms are first introduced, and then specific halogenating reagents, such as fluorohalogenating agents, are gradually introduced to the target position under appropriate reaction conditions. This process requires fine regulation of factors such as reaction temperature, time and reagent dosage. Due to differences in halogenation activity, it is crucial to control the selectivity of the reaction. For example, the selection of a specific catalyst can guide the reaction in the direction of the target product, so that the fluorine atom precisely replaces the hydrogen atom at a specific position, thereby obtaining 1-chloro-2,3,4-trifluorobenzene.
The second is to use other fluorine-containing compounds as raw materials and pass the method of functional group conversion. Select fluorine-containing organic compounds with similar structures and easy to obtain, and then substitution, elimination, addition, etc. through a series of chemical reactions. This method requires a good understanding of various organic reaction mechanisms, and a reasonable reaction route is designed according to the structural characteristics of the raw materials. During the conversion process, attention should be paid to avoid side reactions and ensure the purity and yield of the target product.
Furthermore, the reaction strategy catalyzed by transition metals can be considered. Transition metal catalysts can effectively activate substrate molecules and promote the formation and cleavage of carbon-halogen bonds. Under the synergistic action of suitable ligands, highly selective reactions can be achieved. By selecting suitable transition metal catalysts, ligands and reaction solvents, the reaction conditions are precisely regulated to promote the efficient generation of 1-chloro-2,3,4-trifluorobenzene. Although this method often achieves good results, the cost of catalysts and subsequent separation issues need to be considered.
The above synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to comprehensively consider various factors such as raw material cost, difficulty of reaction conditions, product purity and yield to choose the most suitable synthesis path.
One is the halogenation reaction path. Using a suitable benzene derivative as the starting material, chlorine atoms are first introduced, and then specific halogenating reagents, such as fluorohalogenating agents, are gradually introduced to the target position under appropriate reaction conditions. This process requires fine regulation of factors such as reaction temperature, time and reagent dosage. Due to differences in halogenation activity, it is crucial to control the selectivity of the reaction. For example, the selection of a specific catalyst can guide the reaction in the direction of the target product, so that the fluorine atom precisely replaces the hydrogen atom at a specific position, thereby obtaining 1-chloro-2,3,4-trifluorobenzene.
The second is to use other fluorine-containing compounds as raw materials and pass the method of functional group conversion. Select fluorine-containing organic compounds with similar structures and easy to obtain, and then substitution, elimination, addition, etc. through a series of chemical reactions. This method requires a good understanding of various organic reaction mechanisms, and a reasonable reaction route is designed according to the structural characteristics of the raw materials. During the conversion process, attention should be paid to avoid side reactions and ensure the purity and yield of the target product.
Furthermore, the reaction strategy catalyzed by transition metals can be considered. Transition metal catalysts can effectively activate substrate molecules and promote the formation and cleavage of carbon-halogen bonds. Under the synergistic action of suitable ligands, highly selective reactions can be achieved. By selecting suitable transition metal catalysts, ligands and reaction solvents, the reaction conditions are precisely regulated to promote the efficient generation of 1-chloro-2,3,4-trifluorobenzene. Although this method often achieves good results, the cost of catalysts and subsequent separation issues need to be considered.
The above synthesis methods have their own advantages and disadvantages. In practical applications, it is necessary to comprehensively consider various factors such as raw material cost, difficulty of reaction conditions, product purity and yield to choose the most suitable synthesis path.
What are the precautions for 1-chloro-2,3,4-trifluorobenzene during storage and transportation?
1-Chloro-2,3,4-trifluorobenzene is an organic compound. When storing and transporting, there are several ends that should be paid attention to.
First storage, because of its chemical activity, should be stored in a cool and ventilated warehouse. This is to prevent it from causing chemical reactions due to heat, or even causing danger. The temperature in the warehouse should not be too high, so as not to affect its stability. And it should be kept away from fire and heat sources. Both fire and heat sources can cause accidents such as combustion or explosion. It must be stored separately from oxidants and edible chemicals, because oxidants can oxidize with 1-chloro-2,3,4-trifluorobenzene, and mixed with edible chemicals. Once leaked, it is easy to cause pollution and endanger human health. The storage area should be equipped with suitable materials to contain leaks to prevent accidental leakage from being dealt with in time to avoid the spread of pollution.
Times and transportation, make sure that the container is well sealed before transportation to prevent leakage during transportation. The transportation tool must be clean, dry, and free of residual substances that may react with 1-chloro-2,3,4-trifluorobenzene. During transportation, make sure that the container does not collapse, fall, or damage, and avoid damage to the container due to bumps and collisions. You should follow the prescribed route and do not stop in densely populated areas and residential areas to reduce the harm to the crowd in the event of an accident. When transporting, you need to be equipped with the corresponding variety and quantity of firefighting equipment and leakage emergency treatment equipment, so that you can respond quickly in the event of an emergency.
In this way, during the storage and transportation of 1-chloro-2,3,4-trifluorobenzene, pay attention to the above things to ensure safety and avoid danger.
First storage, because of its chemical activity, should be stored in a cool and ventilated warehouse. This is to prevent it from causing chemical reactions due to heat, or even causing danger. The temperature in the warehouse should not be too high, so as not to affect its stability. And it should be kept away from fire and heat sources. Both fire and heat sources can cause accidents such as combustion or explosion. It must be stored separately from oxidants and edible chemicals, because oxidants can oxidize with 1-chloro-2,3,4-trifluorobenzene, and mixed with edible chemicals. Once leaked, it is easy to cause pollution and endanger human health. The storage area should be equipped with suitable materials to contain leaks to prevent accidental leakage from being dealt with in time to avoid the spread of pollution.
Times and transportation, make sure that the container is well sealed before transportation to prevent leakage during transportation. The transportation tool must be clean, dry, and free of residual substances that may react with 1-chloro-2,3,4-trifluorobenzene. During transportation, make sure that the container does not collapse, fall, or damage, and avoid damage to the container due to bumps and collisions. You should follow the prescribed route and do not stop in densely populated areas and residential areas to reduce the harm to the crowd in the event of an accident. When transporting, you need to be equipped with the corresponding variety and quantity of firefighting equipment and leakage emergency treatment equipment, so that you can respond quickly in the event of an emergency.
In this way, during the storage and transportation of 1-chloro-2,3,4-trifluorobenzene, pay attention to the above things to ensure safety and avoid danger.
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