Linshang Chemical
PRODUCTS
1-Chloro-2,3-Difluoro-6-Nitrobenzene
Linshang Chemical
|
HS Code |
512955 |
| Chemical Formula | C6H2ClF2NO2 |
| Molecular Weight | 195.54 |
| Appearance | Solid (usually) |
| Physical State At Room Temperature | Solid |
| Boiling Point | Data needed |
| Melting Point | Data needed |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in common organic solvents |
| Density | Data needed |
| Vapor Pressure | Data needed |
| Flash Point | Data needed |
| Stability | Stable under normal conditions |
| Hazard Class | Toxic and harmful chemicals |
As an accredited 1-Chloro-2,3-Difluoro-6-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 2,3 - difluoro - 6 - nitrobenzene: Packed in 5 - kg drums for chemical storage. |
| Storage | 1 - Chloro - 2,3 - difluoro - 6 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. It must be kept in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents, reducing agents, and bases to prevent chemical reactions. Label the storage container clearly for easy identification. |
| Shipping | 1 - Chloro - 2,3 - difluoro - 6 - nitrobenzene is a chemical. Shipping requires proper packaging in accordance with hazardous material regulations, likely in sealed containers to prevent leakage during transit. |
Competitive 1-Chloro-2,3-Difluoro-6-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Chloro-2,3-Difluoro-6-Nitrobenzene in China?
As a trusted 1-Chloro-2,3-Difluoro-6-Nitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Chloro-2,3-Difluoro-6-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
1-Chloro-2, what are the physical properties of 3-difluoro-6-nitrobenzene?
1 - chloro - 2,3 - difluoro - 6 - nitrobenzene is an organic compound. Its physical properties are very important and of great significance in the chemical industry and other fields.
This compound is mostly solid at room temperature, and its appearance may be light yellow to yellow crystalline powder. Because of the specific groups such as chlorine, fluorine, and nitro in its molecules, it has unique physical properties.
In terms of melting point, it is about a specific temperature range, and the specific value fluctuates due to purity and other factors. This melting point characteristic has a great impact on its application in different processes. For example, in the process of separation and purification, operations such as recrystallization can be carried out according to the melting point to achieve purification of substances. The boiling point of
is also a key physical property. Under a specific pressure, the temperature at which a compound boils into a gaseous state is related to its behavior in operations such as distillation. The density of
is also a key consideration. The mass per unit volume is specific. This property plays a significant role in processes involving substance mixing and phase separation, which is helpful for judging its distribution in different systems.
In terms of solubility, it has a certain solubility in organic solvents such as toluene and dichloromethane, but it is less soluble in water. This property is extremely important in the selection of reaction solvents and product separation. Reasonable selection of solvents can improve reaction efficiency and product purity.
In addition, the compound has certain stability due to its nitro group, but the presence of nitro groups also allows it to react under specific conditions, such as high temperature, when interacting with specific reagents, showing a lively side. And due to the presence of halogen atoms, it is endowed with certain chemical activities and provides many possibilities for organic synthesis. In short, 1-chloro-2,3-difluoro-6-nitrobenzene has rich and diverse physical properties, which is crucial for its research and application.
This compound is mostly solid at room temperature, and its appearance may be light yellow to yellow crystalline powder. Because of the specific groups such as chlorine, fluorine, and nitro in its molecules, it has unique physical properties.
In terms of melting point, it is about a specific temperature range, and the specific value fluctuates due to purity and other factors. This melting point characteristic has a great impact on its application in different processes. For example, in the process of separation and purification, operations such as recrystallization can be carried out according to the melting point to achieve purification of substances. The boiling point of
is also a key physical property. Under a specific pressure, the temperature at which a compound boils into a gaseous state is related to its behavior in operations such as distillation. The density of
is also a key consideration. The mass per unit volume is specific. This property plays a significant role in processes involving substance mixing and phase separation, which is helpful for judging its distribution in different systems.
In terms of solubility, it has a certain solubility in organic solvents such as toluene and dichloromethane, but it is less soluble in water. This property is extremely important in the selection of reaction solvents and product separation. Reasonable selection of solvents can improve reaction efficiency and product purity.
In addition, the compound has certain stability due to its nitro group, but the presence of nitro groups also allows it to react under specific conditions, such as high temperature, when interacting with specific reagents, showing a lively side. And due to the presence of halogen atoms, it is endowed with certain chemical activities and provides many possibilities for organic synthesis. In short, 1-chloro-2,3-difluoro-6-nitrobenzene has rich and diverse physical properties, which is crucial for its research and application.
What are the chemical properties of 1-chloro-2, 3-difluoro-6-nitrobenzene?
1-Chloro-2,3-difluoro-6-nitrobenzene is also an organic compound. It has the dual characteristics of halogenated aromatics and nitro compounds, both of which give it unique chemical properties.
The first word about its nucleophilic substitution reactivity. Both chlorine and fluorine atoms on the benzene ring can be activated by the strong electron-absorbing effect of nitro groups. Nitro groups reduce the electron cloud density of the benzene ring, making halogen atoms more susceptible to attack by nucleophiles. For example, if nucleophiles such as alkoxides and amines react with it, halogen atoms can be replaced by nucleophilic groups to form corresponding ether or amine derivatives. This reaction is an important means of building carbon-heteroatom bonds in organic synthesis.
Furthermore, its reducing properties. Nitro can be reduced under suitable conditions, common reducing agents such as iron and hydrochloric acid, tin and hydrochloric acid, or catalytic hydrogenation. Nitro can be reduced to obtain amino groups, which are converted from 1-chloro-2,3-difluoro-6-nitrobenzene to 1-chloro-2,3-difluoro-6-aminobenzene. This amino compound can be used as a raw material for further reactions and has wide uses in the preparation of dyes, medicine and other fields.
In addition, the reactivity of its halogen atoms also varies. Generally speaking, fluorine atoms are more difficult to be replaced than chlorine atoms due to their high electronegativity and high C-F bond energy. However, under certain conditions, such as high temperature, the use of strong nucleophiles or catalytic systems, fluorine atoms can also participate in the substitution reaction, providing the possibility for the synthesis of diverse derivatives.
And because of its halogen atom and nitro group, this compound has certain chemical stability and can be stored and handled under moderate conditions. However, it is also necessary to pay attention to its toxicity and potential impact on the environment, and follow relevant safety procedures in experiments and production.
The first word about its nucleophilic substitution reactivity. Both chlorine and fluorine atoms on the benzene ring can be activated by the strong electron-absorbing effect of nitro groups. Nitro groups reduce the electron cloud density of the benzene ring, making halogen atoms more susceptible to attack by nucleophiles. For example, if nucleophiles such as alkoxides and amines react with it, halogen atoms can be replaced by nucleophilic groups to form corresponding ether or amine derivatives. This reaction is an important means of building carbon-heteroatom bonds in organic synthesis.
Furthermore, its reducing properties. Nitro can be reduced under suitable conditions, common reducing agents such as iron and hydrochloric acid, tin and hydrochloric acid, or catalytic hydrogenation. Nitro can be reduced to obtain amino groups, which are converted from 1-chloro-2,3-difluoro-6-nitrobenzene to 1-chloro-2,3-difluoro-6-aminobenzene. This amino compound can be used as a raw material for further reactions and has wide uses in the preparation of dyes, medicine and other fields.
In addition, the reactivity of its halogen atoms also varies. Generally speaking, fluorine atoms are more difficult to be replaced than chlorine atoms due to their high electronegativity and high C-F bond energy. However, under certain conditions, such as high temperature, the use of strong nucleophiles or catalytic systems, fluorine atoms can also participate in the substitution reaction, providing the possibility for the synthesis of diverse derivatives.
And because of its halogen atom and nitro group, this compound has certain chemical stability and can be stored and handled under moderate conditions. However, it is also necessary to pay attention to its toxicity and potential impact on the environment, and follow relevant safety procedures in experiments and production.
What are the main uses of 1-chloro-2, 3-difluoro-6-nitrobenzene?
1-Chloro-2,3-difluoro-6-nitrobenzene is also an organic compound. Its main use is mostly in the field of organic synthesis to demonstrate its ability.
In the synthesis of medicine, this compound is often a key intermediate. Because of the chlorine, fluorine, nitro and other groups attached to the benzene ring, each has unique reactivity. Nitro can be reduced to amino groups. This amino group is an indispensable part in the construction of many drug molecules and can react with other compounds containing carboxyl groups, aldehyde groups and other groups to form complex drug structures. The presence of chlorine and fluorine atoms can adjust the electron cloud distribution and spatial structure of molecules, thereby affecting the binding ability and biological activity of drugs and targets.
In the process of pesticide creation, 1-chloro-2,3-difluoro-6-nitrobenzene also plays an important role. Fluorine atoms endow compounds with higher lipid solubility and stability, making them easier to penetrate biofilms, and have stronger inhibitory effects on certain enzymes of certain pests or weeds. Using it as a starting material, through a series of chemical transformations, pesticide varieties with high efficiency, low toxicity and environmental friendliness can be prepared.
Furthermore, in the field of materials science, this compound can participate in the synthesis of functional polymer materials. Through the polymerization of the active group on the benzene ring with other monomers, it can be introduced into the main chain or side chain of the polymer to impart special properties such as weather resistance and flame retardancy to the material, which can be used to prepare special coatings, engineering plastics, etc., to meet the needs of different industrial scenarios.
In the synthesis of medicine, this compound is often a key intermediate. Because of the chlorine, fluorine, nitro and other groups attached to the benzene ring, each has unique reactivity. Nitro can be reduced to amino groups. This amino group is an indispensable part in the construction of many drug molecules and can react with other compounds containing carboxyl groups, aldehyde groups and other groups to form complex drug structures. The presence of chlorine and fluorine atoms can adjust the electron cloud distribution and spatial structure of molecules, thereby affecting the binding ability and biological activity of drugs and targets.
In the process of pesticide creation, 1-chloro-2,3-difluoro-6-nitrobenzene also plays an important role. Fluorine atoms endow compounds with higher lipid solubility and stability, making them easier to penetrate biofilms, and have stronger inhibitory effects on certain enzymes of certain pests or weeds. Using it as a starting material, through a series of chemical transformations, pesticide varieties with high efficiency, low toxicity and environmental friendliness can be prepared.
Furthermore, in the field of materials science, this compound can participate in the synthesis of functional polymer materials. Through the polymerization of the active group on the benzene ring with other monomers, it can be introduced into the main chain or side chain of the polymer to impart special properties such as weather resistance and flame retardancy to the material, which can be used to prepare special coatings, engineering plastics, etc., to meet the needs of different industrial scenarios.
What are the synthesis methods of 1-chloro-2, 3-difluoro-6-nitrobenzene?
There are several common methods for synthesizing 1-chloro-2,3-difluoro-6-nitrobenzene. First, benzene is used as the initial raw material, and the benzene is nitrified. The mixed acid of concentrated nitric acid and concentrated sulfuric acid is used as the nitrifying reagent. Under appropriate temperature conditions, the benzene ring is introduced into the nitro group to generate nitrobenzene. Then, the nitrobenzene is halogenated, and suitable halogenating reagents, such as chlorine and fluorine, are selected. By controlling the reaction conditions, chlorine atoms and fluorine atoms are introduced at specific positions in the benzene ring. The target product 1-chloro-2,3-difluoro-6-nitrobenzene can be obtained through a multi-step reaction.
Furthermore, halogenated benzene can also be used as the starting material If chlorobenzene is taken as an example, the nitration reaction is carried out on the chlorobenzene first, and the nitro group is introduced into the benzene ring of the chlorobenzene to obtain the chlorobenzene derivative containing the nitro group. After that, through a specific fluorination reaction, the fluorine atom is introduced into the designated position of the benzene ring, and the structure of 1-chloro-2,3-difluoro-6-nitro is formed at the specific position on the benzene ring. In this process, the fluorination reaction is quite critical, and the appropriate fluorination reagent and reaction conditions need to be selected, such as the use of fluorinated reagents such as metal fluoride, and the reaction temperature, time and proportion of the reactants can be adjusted.
Or starting from the difluorobenzene, the difluorobenzene can be nitrified first, Then, the chlorination reaction is carried out, and chlorine atoms are introduced into the benzene ring to obtain 1-chloro-2,3-difluoro-6-nitrobenzene. In this synthesis path, the control of chlorination conditions is also crucial to ensure that chlorine atoms are accurately introduced into the desired position, while minimizing the occurrence of side reactions. Each synthesis method has its advantages and disadvantages. In practice, the most suitable synthesis path should be selected according to the availability of raw materials, the difficulty of controlling the reaction conditions, and the purity requirements of the target product.
Furthermore, halogenated benzene can also be used as the starting material If chlorobenzene is taken as an example, the nitration reaction is carried out on the chlorobenzene first, and the nitro group is introduced into the benzene ring of the chlorobenzene to obtain the chlorobenzene derivative containing the nitro group. After that, through a specific fluorination reaction, the fluorine atom is introduced into the designated position of the benzene ring, and the structure of 1-chloro-2,3-difluoro-6-nitro is formed at the specific position on the benzene ring. In this process, the fluorination reaction is quite critical, and the appropriate fluorination reagent and reaction conditions need to be selected, such as the use of fluorinated reagents such as metal fluoride, and the reaction temperature, time and proportion of the reactants can be adjusted.
Or starting from the difluorobenzene, the difluorobenzene can be nitrified first, Then, the chlorination reaction is carried out, and chlorine atoms are introduced into the benzene ring to obtain 1-chloro-2,3-difluoro-6-nitrobenzene. In this synthesis path, the control of chlorination conditions is also crucial to ensure that chlorine atoms are accurately introduced into the desired position, while minimizing the occurrence of side reactions. Each synthesis method has its advantages and disadvantages. In practice, the most suitable synthesis path should be selected according to the availability of raw materials, the difficulty of controlling the reaction conditions, and the purity requirements of the target product.
1-chloro-2, 3-difluoro-6-nitrobenzene What are the precautions during storage and transportation?
1-Chloro-2,3-difluoro-6-nitrobenzene is also an organic compound. When storing and transporting, it is necessary to pay attention to many matters to prevent accidents and ensure safety.
First, when storing, it is advisable to choose a cool, dry and well-ventilated place. This compound is easy to decompose when heated, so it must be kept away from fire and heat sources, so as not to cause its chemical properties to change due to excessive temperature or even cause danger. The temperature of the warehouse should be controlled within an appropriate range, and it must not be too high.
Second, because of its certain toxicity and corrosiveness, the storage place should be separated from oxidants, acids, bases, etc., and should not be mixed. Otherwise, it is easy to cause chemical reactions, or produce toxic gases, or cause violent reactions, endangering safety. And the storage area should be equipped with suitable materials to contain the leakage, in case of leakage, it can be properly handled in time.
Third, when transporting, the packaging must be tight. Appropriate packaging materials should be selected in accordance with relevant regulations to ensure that there is no damage or leakage during transportation. Transportation vehicles should also be clean, dry, and shall not be mixed with other conflicting items. Transport personnel must be professionally trained to be familiar with the characteristics of this compound and emergency treatment methods. During transportation, close attention should be paid to the condition of the goods. In case of bumps, collisions, etc., the packaging should be checked in good condition in time.
Fourth, whether it is storage or transportation, it must be clearly marked. Indicate its name, hazard category and other important information, so that contacts can see at a glance, so as to operate cautiously and avoid unknowingly causing danger. And a sound emergency plan should be developed to prepare for emergencies and can respond quickly and effectively. In this way, the safety of 1-chloro-2,3-difluoro-6-nitrobenzene during storage and transportation must be ensured.
First, when storing, it is advisable to choose a cool, dry and well-ventilated place. This compound is easy to decompose when heated, so it must be kept away from fire and heat sources, so as not to cause its chemical properties to change due to excessive temperature or even cause danger. The temperature of the warehouse should be controlled within an appropriate range, and it must not be too high.
Second, because of its certain toxicity and corrosiveness, the storage place should be separated from oxidants, acids, bases, etc., and should not be mixed. Otherwise, it is easy to cause chemical reactions, or produce toxic gases, or cause violent reactions, endangering safety. And the storage area should be equipped with suitable materials to contain the leakage, in case of leakage, it can be properly handled in time.
Third, when transporting, the packaging must be tight. Appropriate packaging materials should be selected in accordance with relevant regulations to ensure that there is no damage or leakage during transportation. Transportation vehicles should also be clean, dry, and shall not be mixed with other conflicting items. Transport personnel must be professionally trained to be familiar with the characteristics of this compound and emergency treatment methods. During transportation, close attention should be paid to the condition of the goods. In case of bumps, collisions, etc., the packaging should be checked in good condition in time.
Fourth, whether it is storage or transportation, it must be clearly marked. Indicate its name, hazard category and other important information, so that contacts can see at a glance, so as to operate cautiously and avoid unknowingly causing danger. And a sound emergency plan should be developed to prepare for emergencies and can respond quickly and effectively. In this way, the safety of 1-chloro-2,3-difluoro-6-nitrobenzene during storage and transportation must be ensured.
Scan to WhatsApp
