Linshang Chemical
PRODUCTS
1-Chloro-2,3-Difluorobenzene
Linshang Chemical
|
HS Code |
966249 |
| Chemical Formula | C6H3ClF2 |
| Molecular Weight | 148.54 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 151 - 153 °C |
| Density | 1.32 g/cm³ |
| Flash Point | 47 °C |
| Solubility In Water | Insoluble |
| Odor | Characteristic aromatic odor |
As an accredited 1-Chloro-2,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 2,3 - difluorobenzene packaged in 500 - mL glass bottles, 10 bottles per carton. |
| Storage | 1 - Chloro - 2,3 - difluorobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. It should be kept in a tightly sealed container, preferably made of materials resistant to corrosion. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to prevent potential reactions. |
| Shipping | 1 - Chloro - 2,3 - difluorobenzene is shipped in specialized, tightly - sealed containers. These are designed to prevent leakage, as it's a chemical. Shipments follow strict safety regulations to ensure safe transport. |
Competitive 1-Chloro-2,3-Difluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Chloro-2,3-Difluorobenzene in China?
As a trusted 1-Chloro-2,3-Difluorobenzene manufacturer, we deliver:
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Chloro-2,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-chloro-2,3-difluorobenzene?
1-Chloro-2,3-difluorobenzene is also an organic compound. Its main uses are wide.
In the field of pharmaceutical synthesis, it is often a key intermediate. Molecular structures with specific pharmacological activities can be constructed through various chemical reactions. Due to its unique substituent distribution, it can endow the synthesized drugs with excellent properties, such as enhancing the binding force between the drug and the target, improving the metabolic kinetic characteristics of the drug, etc., so it is indispensable in the creation of new drugs.
It also plays an important role in the creation of pesticides. With it as a starting material, a variety of highly efficient, low-toxic and environmentally friendly pesticide varieties can be derived. Such pesticides are highly selective and highly lethal to pests, and can reduce the negative impact on beneficial organisms and the environment, providing a powerful means for modern agricultural pest control.
In addition, in the field of materials science, 1-chloro-2,3-difluorobenzene has also emerged. It can participate in the synthesis of polymer materials with special functions, such as polymers with excellent heat resistance and chemical stability. These materials are widely used in high-end fields such as electronics and aerospace, and can meet strict use conditions.
In conclusion, 1-chloro-2,3-difluorobenzene, with its unique chemical structure, has shown great value in many fields such as medicine, pesticides, materials, etc., and has made great contributions to the development of related industries.
In the field of pharmaceutical synthesis, it is often a key intermediate. Molecular structures with specific pharmacological activities can be constructed through various chemical reactions. Due to its unique substituent distribution, it can endow the synthesized drugs with excellent properties, such as enhancing the binding force between the drug and the target, improving the metabolic kinetic characteristics of the drug, etc., so it is indispensable in the creation of new drugs.
It also plays an important role in the creation of pesticides. With it as a starting material, a variety of highly efficient, low-toxic and environmentally friendly pesticide varieties can be derived. Such pesticides are highly selective and highly lethal to pests, and can reduce the negative impact on beneficial organisms and the environment, providing a powerful means for modern agricultural pest control.
In addition, in the field of materials science, 1-chloro-2,3-difluorobenzene has also emerged. It can participate in the synthesis of polymer materials with special functions, such as polymers with excellent heat resistance and chemical stability. These materials are widely used in high-end fields such as electronics and aerospace, and can meet strict use conditions.
In conclusion, 1-chloro-2,3-difluorobenzene, with its unique chemical structure, has shown great value in many fields such as medicine, pesticides, materials, etc., and has made great contributions to the development of related industries.
What are the physical properties of 1-chloro-2,3-difluorobenzene?
1-Chloro-2,3-difluorobenzene is also an organic compound. It has specific physical properties and is listed below.
First of all, its properties are colorless to light yellow transparent liquid under normal conditions. It is clear and visible in appearance. This liquid has a special odor, but its taste is not pleasant, and it can be smelled.
Secondary and boiling point, about 172-174 ° C. When the temperature reaches this point, 1-chloro-2,3-difluorobenzene changes from liquid to gaseous state. The temperature of this phase transition is one of its important physical properties.
When it comes to the melting point, it is about -40 ° C. When the temperature drops, the compound solidifies from a liquid state to a solid state, which is another characteristic of it.
Furthermore, density is also an important physical property. Its density is about 1.45g/cm ³, which is heavier than water. If it is placed in one place with water, it will sink underwater.
In terms of solubility, 1-chloro-2,3-difluorobenzene is insoluble in water, and it is mostly suspended in droplets of oil in water or sinks to the bottom. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc., and can be miscible with other organic solvents to form a uniform solution.
Vapor pressure is also taken into account. In a normal temperature environment, its vapor pressure is relatively low, which means that its volatilization rate is relatively slow and it is difficult to evaporate rapidly in air.
The refractive index of 1-chloro-2,3-difluorobenzene is about 1.5030-1.5050. This value is related to the degree of refraction of light when passing through the substance and is one of its optical properties.
To sum up, the physical properties of 1-chloro-2,3-difluorobenzene, such as properties, boiling point, melting point, density, solubility, vapor pressure, refractive index, etc., are the key elements for understanding this substance and are of great significance in many fields such as chemical industry and scientific research.
First of all, its properties are colorless to light yellow transparent liquid under normal conditions. It is clear and visible in appearance. This liquid has a special odor, but its taste is not pleasant, and it can be smelled.
Secondary and boiling point, about 172-174 ° C. When the temperature reaches this point, 1-chloro-2,3-difluorobenzene changes from liquid to gaseous state. The temperature of this phase transition is one of its important physical properties.
When it comes to the melting point, it is about -40 ° C. When the temperature drops, the compound solidifies from a liquid state to a solid state, which is another characteristic of it.
Furthermore, density is also an important physical property. Its density is about 1.45g/cm ³, which is heavier than water. If it is placed in one place with water, it will sink underwater.
In terms of solubility, 1-chloro-2,3-difluorobenzene is insoluble in water, and it is mostly suspended in droplets of oil in water or sinks to the bottom. However, it is soluble in many organic solvents, such as ethanol, ether, acetone, etc., and can be miscible with other organic solvents to form a uniform solution.
Vapor pressure is also taken into account. In a normal temperature environment, its vapor pressure is relatively low, which means that its volatilization rate is relatively slow and it is difficult to evaporate rapidly in air.
The refractive index of 1-chloro-2,3-difluorobenzene is about 1.5030-1.5050. This value is related to the degree of refraction of light when passing through the substance and is one of its optical properties.
To sum up, the physical properties of 1-chloro-2,3-difluorobenzene, such as properties, boiling point, melting point, density, solubility, vapor pressure, refractive index, etc., are the key elements for understanding this substance and are of great significance in many fields such as chemical industry and scientific research.
Is 1-chloro-2,3-difluorobenzene chemically stable?
1-Chloro-2,3-difluorobenzene is also an organic compound. The stability of its chemical properties is related to many factors. Let's discuss it today.
First of all, its chemical bonds. Carbon-chlorine bonds and carbon-fluorine bonds exist in molecules. Carbon-chlorine bonds, the electronegativity of chlorine atoms is greater than that of carbon, so the electron cloud is biased towards chlorine, and this bond has a certain polarity. However, the radius of chlorine atoms is slightly larger, and the bond energy with carbon is relatively non-extremely high. The carbon-fluorine bond is not the same. The fluorine atom is extremely electronegative. When bonding with carbon, the electron cloud is strongly biased towards fluorine, and the radius of the fluorine atom is small, and the carbon-fluorine bond energy is quite high. This is one of the important factors for the stability of the molecular structure.
On its aromaticity. This compound has a benzene ring structure, and the benzene ring has a unique conjugate system. The electrons are delocalized on the entire benzene ring, giving the molecule additional stability. This conjugate effect makes the benzene ring less susceptible to damage by general chemical reactions.
Let's talk about external conditions again. Under normal temperature and pressure and no special chemical reagents or catalysts, 1-chloro-2,3-difluorobenzene However, in case of high temperature, strong oxidizing agent, strong reducing agent or specific catalyst, its stability will be challenged. For example, at high temperature, the carbon-chlorine bond or carbon-fluorine bond may break due to obtaining sufficient energy, causing a chemical reaction to occur. Strong oxidizing agents such as potassium permanganate may attack the side chain of the benzene ring or participate in the substitution reaction on the ring, changing the molecular structure. Strong reducing agents may also promote the reduction of the carbon-halogen bond, causing the detachment of halogen atoms.
In the common nucleophilic substitution reaction in the field of organic synthesis, the electron cloud density of the carbon site connected to the halogen atom on the benzene ring is affected by the fluorine atom and the chlorine atom, and the attack of nucleophilic reagents is difficult The electron-withdrawing effect of fluorine atom reduces the density of adjacent and para-electron clouds. If nucleophiles attack, certain electronic effects need to be overcome.
In summary, 1-chloro-2,3-difluorobenzene has certain chemical stability under specific conditions. However, under suitable reaction conditions, its molecular structure may change and participate in various chemical reactions.
First of all, its chemical bonds. Carbon-chlorine bonds and carbon-fluorine bonds exist in molecules. Carbon-chlorine bonds, the electronegativity of chlorine atoms is greater than that of carbon, so the electron cloud is biased towards chlorine, and this bond has a certain polarity. However, the radius of chlorine atoms is slightly larger, and the bond energy with carbon is relatively non-extremely high. The carbon-fluorine bond is not the same. The fluorine atom is extremely electronegative. When bonding with carbon, the electron cloud is strongly biased towards fluorine, and the radius of the fluorine atom is small, and the carbon-fluorine bond energy is quite high. This is one of the important factors for the stability of the molecular structure.
On its aromaticity. This compound has a benzene ring structure, and the benzene ring has a unique conjugate system. The electrons are delocalized on the entire benzene ring, giving the molecule additional stability. This conjugate effect makes the benzene ring less susceptible to damage by general chemical reactions.
Let's talk about external conditions again. Under normal temperature and pressure and no special chemical reagents or catalysts, 1-chloro-2,3-difluorobenzene However, in case of high temperature, strong oxidizing agent, strong reducing agent or specific catalyst, its stability will be challenged. For example, at high temperature, the carbon-chlorine bond or carbon-fluorine bond may break due to obtaining sufficient energy, causing a chemical reaction to occur. Strong oxidizing agents such as potassium permanganate may attack the side chain of the benzene ring or participate in the substitution reaction on the ring, changing the molecular structure. Strong reducing agents may also promote the reduction of the carbon-halogen bond, causing the detachment of halogen atoms.
In the common nucleophilic substitution reaction in the field of organic synthesis, the electron cloud density of the carbon site connected to the halogen atom on the benzene ring is affected by the fluorine atom and the chlorine atom, and the attack of nucleophilic reagents is difficult The electron-withdrawing effect of fluorine atom reduces the density of adjacent and para-electron clouds. If nucleophiles attack, certain electronic effects need to be overcome.
In summary, 1-chloro-2,3-difluorobenzene has certain chemical stability under specific conditions. However, under suitable reaction conditions, its molecular structure may change and participate in various chemical reactions.
What is the production method of 1-chloro-2,3-difluorobenzene?
The method of making 1-chloro-2,3-difluorobenzene has been around for a long time. The method often follows several paths, each with its own subtlety.
First, start with benzene and go through halogenation. When halogenating, choose an appropriate halogenating agent, such as the halogen of chlorine and fluorine. React benzene and chlorine under suitable conditions to obtain chlorobenzene. Among them, the temperature, pressure and catalyst of the reaction are all key. If the temperature is too high, it may cause side reactions; if it is too low, the reaction will be delayed. The catalyst can help the reaction speed up and increase the yield.
After obtaining chlorobenzene, fluoride. The method of fluorination, or nucleophilic substitution, uses fluoride reagents, such as potassium fluoride, etc., under specific solvents and conditions, so that the chlorine atoms in chlorobenzene are replaced by fluorine atoms. The nature of the solvent has a great influence on the reaction. The choice of polar solvent or non-polar solvent is related to the reaction rate and selectivity.
Second, fluorine-containing aromatics are used as starting materials. After ingeniously designing the reaction path, the existing substituent effect on aromatics can be used to guide the introduction of chlorine atoms and fluorine atoms at the desired position. For example, fluoroaromatics can be localized and activated first to make subsequent halogenation reactions more selective.
During the preparation process, it is necessary to pay attention to the control of the reaction conditions, from temperature, pressure to the proportion of the reactants, there should be no slight difference. And the purification of the product is also a priority, and it often needs to be distilled, extracted, crystallized and other methods to remove impurities and obtain pure 1-chloro-2,3-difluorobenzene. In this way, good products can be obtained and used in many fields, such as the synthesis of medicine and pesticides.
First, start with benzene and go through halogenation. When halogenating, choose an appropriate halogenating agent, such as the halogen of chlorine and fluorine. React benzene and chlorine under suitable conditions to obtain chlorobenzene. Among them, the temperature, pressure and catalyst of the reaction are all key. If the temperature is too high, it may cause side reactions; if it is too low, the reaction will be delayed. The catalyst can help the reaction speed up and increase the yield.
After obtaining chlorobenzene, fluoride. The method of fluorination, or nucleophilic substitution, uses fluoride reagents, such as potassium fluoride, etc., under specific solvents and conditions, so that the chlorine atoms in chlorobenzene are replaced by fluorine atoms. The nature of the solvent has a great influence on the reaction. The choice of polar solvent or non-polar solvent is related to the reaction rate and selectivity.
Second, fluorine-containing aromatics are used as starting materials. After ingeniously designing the reaction path, the existing substituent effect on aromatics can be used to guide the introduction of chlorine atoms and fluorine atoms at the desired position. For example, fluoroaromatics can be localized and activated first to make subsequent halogenation reactions more selective.
During the preparation process, it is necessary to pay attention to the control of the reaction conditions, from temperature, pressure to the proportion of the reactants, there should be no slight difference. And the purification of the product is also a priority, and it often needs to be distilled, extracted, crystallized and other methods to remove impurities and obtain pure 1-chloro-2,3-difluorobenzene. In this way, good products can be obtained and used in many fields, such as the synthesis of medicine and pesticides.
What should be paid attention to when storing and transporting 1-chloro-2,3-difluorobenzene?
1-Chloro-2,3-difluorobenzene is an organic chemical, and its storage and transportation need to be careful to prevent hazards and accidents.
When storing, the first choice of environment. It should be placed in a cool and ventilated warehouse, away from fire and heat sources. Because of its flammability, it can cause combustion in case of open flames and hot topics, so high temperature and fire sources must be avoided. The temperature of the warehouse should be controlled in an appropriate range, generally not exceeding 30 ° C. The humidity should also be adjusted reasonably to prevent chemical reactions caused by high humidity.
Furthermore, storage should be classified. Do not mix with oxidants, acids, alkalis and other storage. 1-Chloro-2,3-difluorobenzene may react violently in contact with oxidizing agents, and may also cause dangerous chemical reactions in contact with acid and alkali, so classified storage is extremely critical.
Packaging should also not be ignored. Packaging containers must be well sealed to ensure no leakage. Commonly used packaging materials should be corrosion-resistant and can effectively block the influence of external factors on them. If special metal or plastic drums are used for packaging, and the barrel body should be marked with important information such as the name of the chemical and the nature of the hazard.
When transporting, the transportation vehicle should be equipped with corresponding fire equipment and leakage emergency treatment equipment. During transportation, it should be protected from sun exposure, rain and high temperature. Summer transportation should be selected in the morning and evening to avoid high temperature and hot sun. If a leak occurs during transportation, emergency measures should be taken quickly to evacuate the surrounding crowd, seal off the scene, and professional personnel should wear protective equipment for cleaning and disposal.
When loading and unloading, operators should wear appropriate protective equipment, such as gas masks, protective gloves, etc. The operation must be handled lightly to prevent damage to packaging and containers and avoid safety accidents caused by the leakage of the chemical.
When storing, the first choice of environment. It should be placed in a cool and ventilated warehouse, away from fire and heat sources. Because of its flammability, it can cause combustion in case of open flames and hot topics, so high temperature and fire sources must be avoided. The temperature of the warehouse should be controlled in an appropriate range, generally not exceeding 30 ° C. The humidity should also be adjusted reasonably to prevent chemical reactions caused by high humidity.
Furthermore, storage should be classified. Do not mix with oxidants, acids, alkalis and other storage. 1-Chloro-2,3-difluorobenzene may react violently in contact with oxidizing agents, and may also cause dangerous chemical reactions in contact with acid and alkali, so classified storage is extremely critical.
Packaging should also not be ignored. Packaging containers must be well sealed to ensure no leakage. Commonly used packaging materials should be corrosion-resistant and can effectively block the influence of external factors on them. If special metal or plastic drums are used for packaging, and the barrel body should be marked with important information such as the name of the chemical and the nature of the hazard.
When transporting, the transportation vehicle should be equipped with corresponding fire equipment and leakage emergency treatment equipment. During transportation, it should be protected from sun exposure, rain and high temperature. Summer transportation should be selected in the morning and evening to avoid high temperature and hot sun. If a leak occurs during transportation, emergency measures should be taken quickly to evacuate the surrounding crowd, seal off the scene, and professional personnel should wear protective equipment for cleaning and disposal.
When loading and unloading, operators should wear appropriate protective equipment, such as gas masks, protective gloves, etc. The operation must be handled lightly to prevent damage to packaging and containers and avoid safety accidents caused by the leakage of the chemical.
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