1-Chloro-2,4-Difluor-6-Onitrobenzene
Linshang Chemical
HS Code |
163576 |
Chemical Formula | C6H2ClF2NO2 |
Molar Mass | 195.53 g/mol |
Appearance | Solid (usually a powder or crystalline solid) |
Physical State At Room Temperature | Solid |
Color | May vary, often colorless to pale - colored |
Odor | Typical aromatic odor (characteristic of benzene - derivatives) |
Melting Point | Specific value would require literature search |
Boiling Point | Specific value would require literature search |
Solubility In Water | Low solubility (organic compound, relatively non - polar) |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone, etc. |
Density | Value would require literature search |
Stability | Stable under normal conditions but may react with strong oxidizing or reducing agents |
Flash Point | Value would require literature search |
Hazard Class | Potentially hazardous, may be toxic, irritant etc. (toxicity details would need further research) |
As an accredited 1-Chloro-2,4-Difluor-6-Onitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 1 - chloro - 2,4 - difluoro - 6 - onitrobenzene packaged in a sealed chemical - grade bottle. |
Storage | 1 - Chloro - 2,4 - difluoro - 6 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and incompatible substances like strong oxidizers and reducing agents. Store in tightly closed containers to prevent leakage and exposure to air and moisture, which could potentially affect its chemical stability. |
Shipping | 1 - Chloro - 2,4 - difluoro - 6 - onitrobenzene is a chemical. It should be shipped in tightly - sealed, corrosion - resistant containers, following strict hazardous materials regulations, ensuring proper labeling and safe transportation conditions. |
Competitive 1-Chloro-2,4-Difluor-6-Onitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1-Chloro-2,4-Difluor-6-Onitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of medicine, 1-chloro-2,4-difluoro-6-nitrobenzene is often used as a key intermediate to synthesize a variety of specific drugs. For example, when developing antibacterial drugs, using this as a starting material, through carefully designed chemical reaction steps, molecular structures with unique antibacterial activities can be constructed, providing powerful weapons for human resistance to bacterial infections.
In the manufacture of pesticides, it plays an indispensable role. With its special chemical structure, a series of high-efficiency and low-toxicity pesticide products can be derived. These pesticides have significant effects on the prevention and control of crop diseases and pests, which can greatly improve the yield and quality of crops, ensure food security, and maintain the sustainable development of agriculture.
The dye industry is also an important application scenario of 1-chloro-2,4-difluoro-6-nitrobenzene. Based on it, through complex synthesis processes, various dyes with bright color and excellent fastness can be prepared. These dyes are widely used in textile, printing and dyeing industries, giving fabrics a variety of colors and meeting people's needs for beautiful clothing and decorative fabrics.
In addition, in emerging fields such as materials science, 1-chloro-2,4-difluoro-6-nitrobenzene also shows potential application value. Researchers are actively exploring the possibility of its application in the synthesis of new functional materials, in order to develop new material systems and promote technological innovation and development in related fields.
To sum up, 1-chloro-2,4-difluoro-6-nitrobenzene plays an irreplaceable role in many industries due to its unique chemical properties and structure, and has a profound impact on modern industry and life.
First of all, its appearance is often white to light yellow crystalline powder. This color and shape are quite critical in identification and preliminary determination. Looking at its texture, it is delicate and regular, and the crystalline state shows that its molecules are arranged in an orderly manner.
When it comes to the melting point, it is about a specific temperature range. The determination of the melting point is an important indicator for identifying this compound, which can help to confirm its purity and distinguish it from other substances. Due to the specific intermolecular forces, the melting point is at a certain value. If the purity changes, the melting point will also vary.
The boiling point is also an important physical property. Under a specific pressure, the compound will boil and vaporize at the corresponding temperature. The boiling point is related to the size, polarity and intermolecular interactions of the molecule. The boiling point of this compound reflects its volatilization characteristics under heating conditions, which is of great significance for separation, purification and temperature control of the reaction process.
Furthermore, the density is also a consideration. Its density determines its space occupied in a specific environment and its distribution when mixed with other substances. The value of density is affected by the molecular structure and the type and number of constituent atoms, providing an important basis for practical operations such as storage and transportation.
Solubility cannot be ignored either. In organic solvents, such as some aromatic hydrocarbons and halogenated hydrocarbon solvents, its solubility is relatively good, while in water it is very little. This difference in solubility is due to the polar characteristics of its molecules, the lipophilicity of organic groups and the influence of nitro and halogen atoms on the overall polarity, which makes it behave differently in different solvents. This property is widely used in chemical synthesis, extraction and separation. The physical properties of 1-chloro-2,4-difluoro-6-nitrobenzene, from its appearance, melting point, boiling point, density, and solubility, play an indispensable role in its research, production, and application in the field of chemistry, providing key information for chemists to control related reactions and processes.
First of all, its nucleophilic substitution reaction. Because of the nitro group attached to the benzene ring, the electron cloud density of the benzene ring decreases, and the electrophilicity of the chlorine atom and the fluorine atom at the check point is enhanced, which is easy to be attacked by nucleophilic reagents. In case of hydroxyl negative ions, nucleophilic substitution can be generated, hydroxyl chlorine or fluorine, and the corresponding phenolic derivatives can be obtained. The mechanism of this reaction is that the nucleophilic reagent first binds to the benzene ring to form an intermediate, and then the leaving group leaves.
The nitro group can be reduced under suitable conditions. If iron and hydrochloric acid are used as the reduction system, the nitro group can be gradually changed to an amino group to obtain an amino-containing compound. In this process, the nitro group is finally formed into an amino group through intermediates such as nitroso and hydroxylamine, providing a method for the introduction of amino groups in organic synthesis.
and its halogenation reaction. Although the electron cloud density of the benzene ring decreases due to the nitro group, halogenation can still occur under certain conditions. For example, under the action of a catalyst, halogen atoms can be introduced at other check points of the benzene ring to expand the diversity of its structure and lay the foundation for the subsequent synthesis of complex organic molecules.
Furthermore, the hydrolysis reaction also has considerable advantages. In an alkaline environment, chlorine atoms or fluorine atoms can be hydrolyzed and replaced by hydroxyl groups. The rate of this reaction is closely related to the conditions, and the alkalinity and temperature can be affected.
1-chloro-2,4-difluoro-6-nitrobenzene has rich chemical properties and is widely used in the field of organic synthesis. It can be converted into various derivatives through various reactions to meet different synthesis needs.
One of the common methods is to use appropriate aromatic hydrocarbons as the starting material. Benzene can be taken as the base first, and the benzene ring can be introduced into the nitro group by the method of nitrification. Nitrobenzene can be obtained by using a mixed acid of concentrated nitric acid and concentrated sulfuric acid as the nitrifying reagent, with moderate temperature control, benzene interacts with the mixed acid phase, and is electrophilically substituted.
Then, the step of halogenation is carried out. Under specific reaction conditions, chlorine and fluorine gas or their corresponding halogenating reagents are used to halogenate nitrobenzene. Select a suitable catalyst, such as iron or other suitable catalysts, so that the chlorine atom and the fluorine atom are introduced into the benzene ring at the desired position, that is, the 1-position, the 2-position, and the 4-position, and then 1-chloro-2,4-difluoro-6-nitrobenzene is obtained.
Or there are other methods, using other simple compounds containing chlorine, fluorine, and nitro as raw materials, through a series of reactions such as condensation and substitution, can also be prepared. However, all methods require detailed consideration of reaction conditions, such as temperature, pressure, and the ratio of reagents, in order to obtain high-yield and high-purity products. This compound is widely used in the fields of organic synthesis, medicinal chemistry, etc. Therefore, the method of preparation is often studied by scholars.
First, this substance is toxic and irritating, and it must be well protected during operation. Wear protective clothing, gloves, and goggles and gas masks to prevent it from coming into contact with the skin, eyes, or inhaling through the respiratory tract, causing physical damage. Due to skin contact, it may cause redness, swelling, itching, and burns; eye contact may cause severe eye pain or visual impairment; inhalation may damage the respiratory system and nervous system.
Second, 1-chloro-2,4-difluoro-6-nitrobenzene flammable substances should be kept away from fire and heat sources. In storage and use places, fireworks are strictly prohibited, and good ventilation is ensured to avoid the formation of explosive mixtures of combustible steam and air. Otherwise, in case of open flame and high heat energy will cause combustion and explosion, resulting in serious safety accidents.
Third, the substance is chemically active and easy to react with a variety of substances. When in use, it is necessary to follow specific reaction conditions and operating procedures, and strictly control the reaction temperature, time and proportion of reactants. The temperature is too high or the time is too long, or the side reaction occurs, which affects the purity and yield of the product; the proportion of reactants is improper, and it is difficult to achieve the expected reaction effect.
Fourth, the storage of 1-chloro-2,4-difluoro-6-nitrobenzene is also exquisite. It should be stored in a cool, dry and well-ventilated place, away from oxidants, acids, alkalis and other substances to prevent chemical reactions. The storage container must be tightly sealed to prevent leakage. At the same time, it is necessary to make a good mark, indicating its name, danger and other information.
Fifth, during use, if leakage occurs, emergency measures should be taken immediately. Quickly evacuate personnel from the spill-contaminated area to a safe area, quarantine them, and strictly limit access. Emergency personnel need to wear protective equipment and do not directly contact the spill. In the case of a small amount of leakage, inert materials such as sand and vermiculite can be used to absorb it; in the case of a large amount of leakage, a dike should be built or dug for containment, and transferred to a tanker or a special collector by pump for recycling or transportation to a waste treatment site for disposal.
In short, when using 1-chloro-2,4-difluoro-6-nitrobenzene, it is necessary to be cautious and strictly abide by relevant safety regulations and operating procedures to ensure personal safety and the safety of the production process.

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