1-Chloro-2,4-Difluoro-3-Nitrobenzene
Linshang Chemical
HS Code |
982536 |
Chemical Formula | C6H2ClF2NO2 |
Molecular Weight | 193.535 |
Appearance | Yellow - brown liquid |
Boiling Point | 215 - 217 °C |
Melting Point | 30 - 32 °C |
Density | 1.61 g/cm³ |
Solubility In Water | Insoluble |
Flash Point | 94 °C |
Vapor Pressure | Low |
Stability | Stable under normal conditions |
As an accredited 1-Chloro-2,4-Difluoro-3-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 - chloro - 2,4 - difluoro - 3 - nitrobenzene packaged in 1 - kg bottles. |
Storage | 1 - Chloro - 2,4 - difluoro - 3 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials. Avoid exposure to moisture as it may react or degrade the chemical. Label the storage clearly for easy identification and safety. |
Shipping | 1 - chloro - 2,4 - difluoro - 3 - nitrobenzene is a chemical. Ship it in tightly sealed, corrosion - resistant containers. Follow all hazardous material shipping regulations, ensuring proper labeling for safe transportation. |
Competitive 1-Chloro-2,4-Difluoro-3-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1-Chloro-2,4-Difluoro-3-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Furthermore, in the process of pesticide creation, 1-chloro-2,4-difluoro-3-nitrobenzene also plays an important role. Through ingenious chemical modification and transformation, it can be constructed into a pesticide component with high-efficiency insecticidal, herbicidal or bactericidal properties. Its unique chemical activity can enable pesticides to precisely act on specific target organisms, enhance the efficacy of drugs, reduce the adverse impact on the environment, and help the sustainable development of agriculture.
In addition, in the field of material science, this compound also has extraordinary performance. After a specific reaction and polymerization process, it can be introduced into polymer materials, giving the materials excellent properties such as chemical corrosion resistance and high temperature resistance. Thereby expanding the application field of materials and finding a place in high-end fields such as aerospace, electronics and electrical appliances.
In summary, 1-chloro-2,4-difluoro-3-nitrobenzene has shown great application value in many fields such as medicine, pesticides and materials science due to its unique chemical structure and activity, and has made great contributions to the development of various fields.
First of all, its appearance, under room temperature and pressure, is mostly colorless to light yellow liquid, with a clear texture. It looks quite fluid, like smart water, but it has unique chemical properties.
Describe its melting point. The melting point is between -10 ° C and -5 ° C, just like the critical temperature in winter. At this low temperature, it gradually condenses from liquid to solid. The boiling point is in the range of 200 ° C to 210 ° C, and a higher temperature is required to make it boil and turn into a gaseous state. This boiling point characteristic is crucial in chemical operations such as separation and purification. If properly controlled, pure things can be accurately obtained.
Furthermore, when it comes to density, it is about 1.6 g/cm ³, which is heavier than water. If placed in water, such as a stone sinking abyss, it sinks directly. This density difference can be separated by the principle of density difference, and the liquid separation and other operations can be carried out.
The solubility cannot be ignored. It is slightly soluble in water, such as oil floating in water, and the two are difficult to blend. Due to the large difference in polarity between the two. However, in organic solvents, such as ethanol, ether, acetone, etc., it has good solubility, just like fish entering water and dispersing freely. This solubility characteristic can be well utilized in organic synthesis, extraction and other processes, and a suitable organic solvent can be selected to fully dissolve the compound to facilitate subsequent reactions or separation.
In terms of volatility, its volatility is low. At room temperature, the volatilization rate in the air is slow, and it is not easy to quickly escape into the environment. This characteristic can reduce volatilization loss and reduce potential harm to the environment and human body during storage and use.
The physical properties of 1-chloro-2,4-difluoro-3-nitrobenzene are of critical significance in many fields such as chemical production and scientific research, laying the foundation for related operations and applications.
First, the appropriate aromatic hydrocarbon is used as the starting material, and the nitro group is introduced first. The aromatic hydrocarbon can be placed in a specific reaction vessel, and an appropriate amount of mixed acid (mixture of nitric acid and sulfuric acid) can be added to control the reaction temperature and time. Due to the localization effect of nitro groups, the subsequent substitution reaction can be more selective. After the nitro group is successfully introduced, the halogenation reaction is carried out. A suitable halogenating agent, such as a halogenating agent containing chlorine and fluorine, can be used to replace the corresponding hydrogen atoms on the benzene ring with chlorine atoms and fluorine atoms in the presence of a catalyst to obtain 1-chloro-2,4-difluoro-3-nitrobenzene.
Second, a halogenation reaction can also be carried out first. First, the aromatic hydrocarbon is reacted with the halogenating agent, so that the chlorine atom and the fluorine atom replace the hydrogen on the benzene ring. Subsequently, a nitrifying agent, such as a mixed acid system composed of nitric acid and sulfuric acid, is used to introduce the nitro group into the benzene ring under appropriate reaction conditions to achieve the purpose of synthesizing the target product. This process requires fine regulation of reaction conditions, such as temperature, reactant ratio, etc., to ensure that each step of the reaction proceeds smoothly and the product purity is guaranteed.
Furthermore, some special synthesis paths can also be considered. For example, the reaction catalyzed by transition metals. By selecting suitable transition metal catalysts to cross-couple benzene derivatives containing specific substituents, etc., the structure of the target product is gradually constructed. Although this method may be more complicated, in some cases, it can effectively improve the selectivity and yield of the reaction.
In conclusion, there are various methods for synthesizing 1-chloro-2,4-difluoro-3-nitrobenzene, and the appropriate synthesis path should be selected according to the actual situation, such as the availability of raw materials, the controllability of reaction conditions, and the purity requirements of the product.
One is storage. This compound should be stored in a cool, dry and well-ventilated place. Because heat can easily cause its chemical instability, or even cause danger, it should be kept away from fire and heat sources, and must not be exposed to the sun. And it is sensitive to moisture, damp or contact with water, or reaction, affecting the quality, be sure to ensure that the storage environment is dry. Storage containers must also be tight to prevent leakage, and corrosion-resistant materials should be selected. Containers made of glass or specific plastic materials should be covered because they are corrosive, or suitable. At the same time, it should be stored separately from oxidizing agents, reducing agents, alkalis, etc., to avoid mixed storage to prevent chemical reactions.
The second is related to transportation. During transportation, ensure that the container is firm and prevent collision and vibration from causing damage and leakage of the container. It is necessary to follow the relevant regulations on the transportation of hazardous chemicals and be equipped with corresponding emergency treatment equipment and protective equipment. Transportation vehicles should also have good ventilation conditions and be away from densely populated areas and fire sources. If a leak occurs during transportation, emergency measures should be taken immediately to evacuate the surrounding people, isolate the leakage area, and strictly prohibit unrelated personnel from approaching. When handling leaks, it is necessary to wear appropriate protective equipment, do not come into direct contact, and use appropriate methods to clean up according to the amount of leakage. A small amount of leakage can be absorbed by inert materials such as sand, and a large amount of leakage needs to be constructed or excavated for containment, and then properly handled.
All of these are due attention during the storage and transportation of 1-chloro-2,4-difluoro-3-nitrobenzene, so as to ensure the safety of personnel and the environment is not endangered.
First of all, its impact on the environment. If this compound is released in nature, it can cause harm in water, soil and atmosphere. In water, it may affect the survival and reproduction of aquatic organisms. Because of its toxicity, it can poison aquatic organisms such as fish and shellfish, causing damage to their physiological functions and even death, destroying the balance of aquatic ecosystems. In soil, it may change the chemical properties of soil, affect the activities of soil microorganisms, and then affect the absorption of nutrients by plants, hinder plant growth, and have adverse effects on terrestrial ecosystems. In the atmosphere, it evaporates, or participates in photochemical reactions, generating harmful secondary pollutants, which affect air quality.
As for the impact on human health, it is also quite serious. It can enter the human body through breathing, skin contact or ingestion. If inhaled air containing this compound, it can irritate the respiratory tract, causing symptoms such as cough and asthma. Long-term inhalation may damage lung function and increase the risk of respiratory diseases. If exposed to the skin, it may cause skin allergies, redness, swelling, itching and other discomforts. If ingested accidentally, it can damage the digestive system, cause nausea, vomiting, abdominal pain and other phenomena. What's more, it may affect the function of important organs such as the liver and kidneys, endangering life.
From this perspective, 1-chloro-2,4-difluoro-3-nitrobenzene poses a potential threat to both the environment and human health, and must be treated with caution during its production, use and disposal to reduce its harm to the environment and people.

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