1-Chloro-2,4-Dimethylbenzene
Linshang Chemical
HS Code |
172431 |
Chemical Formula | C8H9Cl |
Molar Mass | 140.61 g/mol |
Appearance | Colorless to pale yellow liquid |
Odor | Aromatic odor |
Density | 1.05 g/cm³ at 20 °C |
Boiling Point | 195 - 197 °C |
Melting Point | -25 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in most organic solvents |
Flash Point | 72 °C |
Vapor Pressure | 0.17 mmHg at 25 °C |
Refractive Index | 1.537 at 20 °C |
As an accredited 1-Chloro-2,4-Dimethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 - chloro - 2,4 - dimethylbenzene: Packed in 500 - mL glass bottles, one bottle per pack. |
Storage | 1 - Chloro - 2,4 - dimethylbenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and reactive chemicals. Use proper storage cabinets or areas compliant with safety regulations to ensure its stability and prevent potential hazards. |
Shipping | 1 - Chloro - 2,4 - dimethylbenzene is shipped in tightly sealed, corrosion - resistant containers. These are carefully packed in larger units to prevent damage during transit, ensuring safe transportation of this chemical. |
Competitive 1-Chloro-2,4-Dimethylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 1-Chloro-2,4-Dimethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
The first word is the nucleophilic substitution reaction. Among this compound, the chlorine atom is more active. The edge chlorine atom is electronegative, which causes the bond connected to the benzene ring to be polar. Therefore, in the case of nucleophilic reagents, the nucleophilic reagent can attack the carbon atom connected to the chlorine, and the chloride ion leaves, so the nucleophilic substitution product is formed. For example, when it is co-heated with an aqueous solution of sodium hydroxide, the hydroxyl nucleophilic reagent attacks, and the chlorine is replaced by the hydroxyl group to produce 2,4-dimethylphenol.
Furthermore, it can participate in The benzene ring is electron-rich. Although chlorine and methyl have different effects on the electron cloud density of the benzene ring, the whole can still react with electrophilic reagents. Methyl is an electron donor group, which increases the electron cloud density of the ortho and para-position of the benzene ring. Therefore, electrophilic substitutions mostly occur in the ortho and para-position of methyl. If mixed with nitric acid and sulfuric acid, nitro substitutions can be formed. Under suitable conditions, nitro groups may be introduced into the ortho or para-position of methyl.
In addition, 1-chloro-2,4-dimethylbenzene can be eliminated. Under strong alkali and heating conditions, the hydrogen atom on the chlorine atom and the ortho-carbon atom can be removed to form an unsaturated double bond structure, forming products such as 2,4-dimethylstyrene.
In addition, it also exhibits in oxidation reactions. Although the benzene ring is relatively stable, the A of the side chain can be oxidized under certain conditions. If treated with a strong oxidizing agent, such as acidic potassium permanganate solution, the methyl group may be oxidized to a carboxyl group to obtain the corresponding chlorobenzoic acid derivative.
In short, the characteristics of chlorine atoms, benzene rings and methyl groups in the structure of 1-chloro-2,4-dimethylbenzene show a variety of chemical reactivity and are quite useful in organic synthesis and other fields.
First, in the field of organic synthesis, this is an important raw material. It can be used to construct various organic compounds by many chemical reactions, such as nucleophilic substitution reactions. Its chlorine atom is active and can react with many nucleophilic reagents, such as alkoxides and amines, to form ether and amine derivatives. This property makes it a key starting material for the synthesis of complex organic molecules, and it plays a significant role in the synthesis of fine chemical products.
Second, in the field of materials science, it can be used as an intermediate for the preparation of polymer materials. Through polymerization, its structural units are introduced into the polymer chain to give the material specific properties. Such as the synthesis of polymers with special solubility and thermal stability, used in coatings, plastics and other fields to improve the comprehensive properties of materials.
Third, it also plays an important role in the manufacture of medicine and pesticides. Because of its unique chemical structure, it can become biologically active molecules after appropriate modification and transformation. Some compounds containing 1-chloro-2,4-dimethylbenzene structure have inhibitory or killing effects on specific pests and diseases, or exhibit pharmacological activity in the field of medicine, providing a structural basis for the development of new drugs.
Fourth, in the fragrance industry, it can be used as a starting material for fragrance synthesis. Through a series of chemical reactions to modify its structure, compounds with unique aromas can be obtained, which can be used to prepare various flavors and add pleasant flavors to products.
In summary, although 1-chloro-2,4-dimethylbenzene is an organic compound, it has a wide range of and critical uses in many fields, and is of great significance to industrial production and scientific research.
First, the halogenation method. Using 2,4-dimethylbenzene as the starting material, under appropriate reaction conditions, it is halogenated with a chlorine source. Commonly used chlorine sources include chlorine gas, hydrogen chloride, etc. During the reaction, catalysts, such as ferric chloride, aluminum trichloride and other Lewis acid catalysts, are usually added to promote the reaction. The mechanism of this reaction is an electrophilic substitution reaction. Under the action of chlorine or hydrogen chloride in the catalyst, an active electrophilic reagent is formed, which attacks the benzene ring of 2,4-dimethylbenzene and replaces the hydrogen atom on it to obtain 1-chloro-2,4-dimethylbenzene. It should be noted that the control of reaction conditions is very critical, such as reaction temperature, reactant ratio, reaction time, etc., which will affect the yield and purity of the product. Generally speaking, lower temperatures are conducive to the formation of a substituted product, while higher temperatures may lead to the formation of multiple substituted products.
Second, the diazonium salt method. First, the diazonium salt is prepared by the diazotization reaction of 2,4-dimethylaniline, and then the diazonium salt is subjected to a Sandmaier reaction with reagents such as cuprous chloride, thereby introducing chlorine atoms to generate 1-chloro-2,4-dimethylbenzene. The specific steps are as follows: Dissolve 2,4-dimethylaniline in an appropriate amount of acid (such as hydrochloric acid), cool it to a low temperature, generally at 0-5 ° C, slowly add sodium nitrite solution, carry out diazotization reaction, and generate a diazonium salt solution. Subsequently, the diazonium salt solution is added to the hydrochloric acid solution containing cuprous chloride, and the reaction is heated. The diazonium group is replaced by a chlorine atom to obtain the target product. The advantage of this method is that the reaction selectivity is high, and chlorine atoms can be introduced at specific positions more accurately.
Third, the Grignard reagent method. Using 2,4-dimethyl bromobenzene as raw material, the Grignard reagent is first prepared, that is, 2,4-dimethyl phenyl magnesium bromide. The specific preparation method is that 2,4-dimethyl bromobenzene is dissolved in an anhydrous ether and other organic solvents, and magnesium chips are added. Under the action of the initiator, the Grignard reagent is reacted to form a Grignard reagent. After that, the Grignard reagent is reacted with chlorinated reagents (such as zinc chloride, ferric chloride, etc.), and the subsequent treatment such as hydrolysis can obtain 1-chloro-2,4-dimethyl ben The key to this method is that the preparation of Grignard reagents needs to be carried out under strict conditions without water and oxygen, otherwise it is easy to lead to side reactions and affect the formation of products.
The above methods for preparing 1-chloro-2,4-dimethyl benzene have their own advantages and disadvantages. In practical applications, appropriate preparation methods should be carefully selected according to specific needs, availability of raw materials, cost and other factors.
First of all, it is volatile, escapes into the atmosphere, or causes air quality to decline. If people are exposed to this environment, inhaling the air containing this substance may damage the respiratory tract and nervous system. In the atmosphere, it may participate in photochemical reactions to generate secondary pollutants such as ozone, causing photochemical smog, endangering human health and the ecological environment.
Furthermore, if it enters the water body, it will be hydrophobic or adsorbed on suspended particles, settle to the bottom sediment, and accumulate for a long time, posing a threat to aquatic life. Contact with aquatic animals such as fish, or abnormal physiological functions, affect reproduction and growth, cause changes in population numbers, and disrupt aquatic ecological balance.
In addition, if soil is polluted with 1-chloro-2,4-dimethylbenzene, it will affect soil microbial activity and community structure. Soil microorganisms are essential for soil nutrient cycling and decomposition of organic matter. If they are disturbed, they may cause soil fertility to decline, affecting plant growth. Plants absorb this substance, or accumulate it in their bodies, and pass it through the food chain, which is toxic to high-nutrient organisms and threatens the stability of the entire ecosystem.
In summary, the diffusion of 1-chloro-2,4-dimethylbenzene in the environment will affect environmental factors such as air, water, and soil in various ways, threatening ecosystem safety and human health. Therefore, it is necessary to strictly control its production, use, and emissions to reduce environmental risks.
One is related to storage. This compound should be stored in a cool and well-ventilated place. It is dangerous due to heat, and high temperature can cause it to evaporate, or even cause a chemical reaction. The temperature of the warehouse should be controlled within an appropriate range, and it must not be too high. At the same time, be sure to keep away from fires and heat sources. Close proximity to an open flame is likely to cause it to burn and cause a fire. Furthermore, it should be stored separately from oxidants, acids, alkalis, etc. Because of its active chemical properties, contact with these substances, or react violently, endangering safety. The storage area should also be equipped with suitable containment materials to prevent timely handling in case of leakage.
Second, it involves transportation. Before transportation, ensure that the packaging is complete and well sealed to prevent leakage during transportation. The means of transportation should be clean and free of other residues that may react with it. During transportation, it is necessary to prevent exposure to sunlight, rain, and avoid high temperature and humid environments. It is necessary to follow the specified route and stay away from densely populated areas to prevent serious consequences in the event of an accident. Transport personnel must also undergo professional training, be familiar with the characteristics of the compound and emergency treatment methods, and ensure the safety of the whole transportation process. In this way, the safety of 1-chloro-2,4-dimethylbenzene during storage and transportation can be guaranteed to avoid accidents.

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