1-Chloro-2-[(4-Ethoxyphenyl)Methyl]-4-Iodo-Benzene
Linshang Chemical
HS Code |
202740 |
Chemical Formula | C15H14ClIO |
Molecular Weight | 388.63 |
Appearance | Solid (usually) |
Physical State At Room Temperature | Solid |
Odor | Typically odorless or faint organic odor |
Solubility In Water | Low solubility |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
Melting Point | Specific value would require experimental determination |
Boiling Point | Specific value would require experimental determination |
Density | Specific value would require experimental determination |
Stability | Stable under normal conditions but may react with strong oxidizing agents |
As an accredited 1-Chloro-2-[(4-Ethoxyphenyl)Methyl]-4-Iodo-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100g of 1 - chloro - 2 - [(4 - ethoxyphenyl)methyl] - 4 - iodo - benzene in sealed, labeled containers. |
Storage | 1 - Chloro - 2 - [(4 - ethoxyphenyl)methyl] - 4 - iodo - benzene should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to degradation. Store it separately from incompatible substances like strong oxidizers to avoid chemical reactions. |
Shipping | 1 - chloro - 2 - [(4 - ethoxyphenyl)methyl] - 4 - iodo - benzene will be shipped in sealed, corrosion - resistant containers. Shipment will follow strict chemical transport regulations, ensuring safety during transit. |
Competitive 1-Chloro-2-[(4-Ethoxyphenyl)Methyl]-4-Iodo-Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 1-Chloro-2-[(4-Ethoxyphenyl)Methyl]-4-Iodo-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Wherein, the methyl structure of (4-ethoxyphenyl) is: an ethoxy group is attached to the fourth position of the phenyl group, and the phenyl group is then connected to the second position of the benzene ring through methylene (-CH -2 -). As a whole, the compound has a benzene ring as the core, with a chlorine atom at No. 1, an iodine atom at No. 4, and a 4-ethoxyphenyl group at No. 2 through methylene. In this way, the chemical structure of 1-chloro-2- [ (4-ethoxyphenyl) methyl] -4-iodobenzene is clearly presented.
Melting point is critical for the identification and purification of this compound. Experiments have determined that its melting point is in a specific temperature range, which is determined by intermolecular forces, such as van der Waals forces and hydrogen bonds. These forces maintain the lattice structure and require specific energy to overcome when heated to transform into a liquid state.
Solubility is also an important property. The compound has a certain solubility in organic solvents such as dichloromethane and chloroform. Because its molecular structure contains a hydrophobic part, it has a similar miscibility with organic solvent molecules. However, its solubility in water is poor. Because water is a polar solvent, the overall polarity of this compound is weak, and it is difficult to form an effective interaction with water molecules.
Density is one of the characteristics of the substance. 1-chloro-2- [ (4-ethoxyphenyl) methyl] -4-iodo-benzene density depends on the molecular weight and the way of molecular accumulation. It can be accurately measured by experiments and is of great significance for related chemical processes such as distribution in mixed systems. In addition, its volatility is low, due to relatively strong intermolecular forces, it is not easy to transition from liquid or solid to gaseous escape, and it has high stability during storage and use. It can be stored under conventional conditions with less volatile loss.
First, the halogenated aromatic hydrocarbon coupling method. First, a halogenated benzene derivative containing a suitable substituent, such as 2 - [ (4 - ethoxyphenyl) methyl] - 4 - iodo - benzene, is prepared, and then catalyzed by a transition metal to couple it with a chlorinated reagent. Often palladium catalysts, such as Pd (PPh), etc., are reacted in suitable organic solvents in the presence of bases. This process requires precise control of the reaction conditions, such as temperature, reaction time, etc., to improve the yield and selectivity.
Second, nucleophilic substitution method. If a benzene derivative containing a leavable group has been obtained, and the activity of the group is suitable, it can undergo nucleophilic substitution reaction with the nucleophilic reagent chlorine anion. However, it is necessary to pay attention to the structure of the substrate to ensure the selectivity of the reaction check point. This purpose can be achieved by appropriate activation or protection of the substrate.
Third, through the gradual construction of benzene ring method. Using suitable aromatic compounds as starting materials, through Friedel-Crafts reaction, etc., the required substituents are gradually introduced. For example, 4-ethoxytoluene is first used as raw material, through Friedel-Crafts alkylation reaction, chloromethyl is introduced at a specific position in the benzene ring, and then iodine atoms are introduced through halogenation reaction, and finally the methyl is oxidized or other conversions to obtain the target product. This path requires clever design of reaction steps to avoid the occurrence of side reactions.
No matter what method is used, the reaction conditions must be carefully controlled, including temperature, solvent, catalyst dosage, etc., and the synthesis process often involves multiple steps. Each step needs to be carefully operated to ensure that 1-chloro-2 - [ (4-ethoxyphenyl) methyl] - 4 - iodo - benzene can be obtained efficiently and with high purity.
Looking at the field of pharmaceutical research and development, organic compounds are often the cornerstone of the creation of new drugs. The unique molecular structure of this compound may have specific biological activities. Or it can be combined with specific targets in organisms, like a delicate key to fit a precise keyhole, and then affect the physiological and biochemical processes in organisms. Or it can be used to explore new therapeutic drugs for specific diseases. For example, in the research and development of anti-tumor drugs, such compounds may demonstrate their potential medicinal value by interfering with key processes such as the proliferation and invasion of tumor cells.
In the field of materials science, it may also have extraordinary performance. Organic compounds can often be chemically modified and processed to shape materials with special properties. This compound may be used to prepare new photoelectric materials due to its intermolecular interactions and electronic structure properties. It may emerge in the fields of organic Light Emitting Diode (OLED), solar cells, etc., contributing to the improvement of the photoelectric conversion efficiency and stability of such materials.
Furthermore, in the field of organic synthetic chemistry, this compound can be used as an important synthesis intermediate. Chemists can modify and derive its structure through various organic reactions. By introducing different functional groups to build more complex and diverse organic molecular structures, it opens up the way for the synthesis of organic compounds with specific functions and uses, and promotes the development and progress of organic synthetic chemistry, enabling scientists to create more novel and practical organic compounds.
In the chemical industry, this compound may be used as an intermediate to lay the foundation for the synthesis of more complex organic molecules. However, its market prospects are subject to many factors.
From a demand perspective, if the demand for complex compounds containing this structure in downstream industries, such as medicine, materials, etc., increases, the market prospects are quite promising. For example, in pharmaceutical research and development, compounds with specific structures or unique biological activities, if this compound can be used as a key intermediate to participate in the synthesis of drugs with therapeutic effects, the demand will rise.
Furthermore, synthesis technology also affects its market. If the synthesis method is simple, efficient and inexpensive, its market competitiveness can be enhanced. On the contrary, if the synthesis process is cumbersome and costly, its large-scale production and application must be restricted.
In addition, regulations and policies cannot be ignored. The chemical industry is strictly regulated. If this compound meets the requirements of environmental protection and safety regulations, it can enter the market smoothly, otherwise its market development will be hindered.
Although it is difficult to predict its market prospects at present, considering the above factors, if it can meet downstream demand, optimize synthesis technology, and comply with regulations, it may gain a foothold in the chemical intermediates market.

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