Linshang Chemical
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1-Chloro-2-(Chlorodiphenylmethyl)Benzene
Linshang Chemical
|
HS Code |
813297 |
| Chemical Formula | C19H14Cl2 |
| Molar Mass | 313.22 g/mol |
| Appearance | Solid |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents |
| Stability | Stable under normal conditions |
| Hazardous Decomposition Products | Chlorinated organic compounds upon combustion |
As an accredited 1-Chloro-2-(Chlorodiphenylmethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1 - chloro - 2 - (chlorodiphenylmethyl)benzene packaged in a sealed plastic bottle. |
| Storage | 1 - chloro - 2 - (chlorodiphenylmethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and incompatible substances to prevent potential reactions. |
| Shipping | 1 - chloro - 2 - (chlorodiphenylmethyl)benzene is a chemical. Shipping should be in accordance with hazardous material regulations. Use appropriate packaging to prevent leakage, and ensure proper labeling for safe transport. |
Competitive 1-Chloro-2-(Chlorodiphenylmethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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What are the chemical properties of 1-chloro-2- (chlorodiphenylmethyl) benzene
1 - chloro - 2 - (chlorodiphenylmethyl) benzene, the Chinese name is often 2 - (chlorodiphenylmethyl) - 1 - chlorobenzene. The chemical properties of this substance are rich.
In terms of its anti-activity, there are chlorine atoms in the molecule, and the chlorine atoms have certain properties because of their properties. Among them, the chlorine atoms in the benzene phase are affected by the benzene effect, and can be used for multiple reactions. For example, in the case of benzene, this chlorine atom can generate a nucleus and replace the anti-reaction. Provide a nucleus to attack the carbon atoms of the chlorine atoms. The chlorine atoms are removed in the form of chlorine atoms to form new compounds.
And the chlorodiphenyl methyl part on the benzene also has special inverse properties. The co-activity of diphenyl methyl is due to benzene, so that the characterization of the benzene part is different from that of ordinary alkyl groups. Its chlorine atom can be nucleally substituted with benzene, and the chlorine atom with benzene direct phase has inverse activity due to the sub-effect of diphenyl methyl. In addition, the benzene part of this molecule can perform typical inverse reactions of aromatic compounds, such as benzene substitution inverse. Due to the rich child nature of benzene, it is vulnerable to inverse attack. Under suitable conditions, new substituents can be introduced on benzene.
In terms of physical rationality, it is usually solid or liquid, and has a certain melting boiling. Because the molecule contains chlorine atoms, the phase density is higher than that of water. And due to the molecular action of the molecule, there may be a certain solubility in the solution, but the solubility in water is small. Therefore, 1-chloro-2 - (chlorodiphenylmethyl) benzene, due to its special properties, exhibits many properties in the chemical and physical properties.
In terms of its anti-activity, there are chlorine atoms in the molecule, and the chlorine atoms have certain properties because of their properties. Among them, the chlorine atoms in the benzene phase are affected by the benzene effect, and can be used for multiple reactions. For example, in the case of benzene, this chlorine atom can generate a nucleus and replace the anti-reaction. Provide a nucleus to attack the carbon atoms of the chlorine atoms. The chlorine atoms are removed in the form of chlorine atoms to form new compounds.
And the chlorodiphenyl methyl part on the benzene also has special inverse properties. The co-activity of diphenyl methyl is due to benzene, so that the characterization of the benzene part is different from that of ordinary alkyl groups. Its chlorine atom can be nucleally substituted with benzene, and the chlorine atom with benzene direct phase has inverse activity due to the sub-effect of diphenyl methyl. In addition, the benzene part of this molecule can perform typical inverse reactions of aromatic compounds, such as benzene substitution inverse. Due to the rich child nature of benzene, it is vulnerable to inverse attack. Under suitable conditions, new substituents can be introduced on benzene.
In terms of physical rationality, it is usually solid or liquid, and has a certain melting boiling. Because the molecule contains chlorine atoms, the phase density is higher than that of water. And due to the molecular action of the molecule, there may be a certain solubility in the solution, but the solubility in water is small. Therefore, 1-chloro-2 - (chlorodiphenylmethyl) benzene, due to its special properties, exhibits many properties in the chemical and physical properties.
What are the main uses of 1-chloro-2- (chlorodiphenylmethyl) benzene
1 - chloro - 2 - (chlorodiphenylmethyl) benzene is 1 - chloro - 2 - (chlorodiphenylmethyl) benzene, which has a wide range of uses.
In the field of organic synthesis, it is an important intermediate. The presence of chlorine atoms and chlorodiphenylmethyl in its structure endows it with active chemical properties and can participate in various chemical reactions, such as nucleophilic substitution reactions. Nucleophilic reagents can attack the carbon atoms connected to the chlorine atoms, causing the chlorine atoms to leave, and then form new carbon-heteroatom bonds. Through this, various complex organic compounds can be synthesized, which is of great significance in the fields of pharmaceutical chemistry and materials science.
At the level of drug development, using this as a starting material, molecular structures with specific biological activities can be constructed through multi-step reactions. Or its structure can be modified to make the synthesized drug molecules more suitable for the target, enhance the interaction with biomacromolecules, improve drug efficacy, reduce toxic and side effects. For example, the pharmacokinetics and pharmacodynamics of drugs can be optimized by adjusting the substituents on the benzene ring, changing the hydrophobicity and electron cloud distribution of the molecule.
In the field of materials science, it can be used to prepare functional polymer materials. By polymerizing with other monomers, this structure is introduced into the main chain or side chain of the polymer, giving the material unique properties. For example, because it contains a large benzene ring structure, it can improve the rigidity and thermal stability of the material; the presence of chlorine atoms can participate in subsequent reactions to modify the surface of the material to improve the adhesion and corrosion resistance of the material.
Furthermore, it is also used in the dye industry. Using its structure, specific chromophore compounds can be derived as synthetic precursors of new dyes. By modifying its structure, the color, light resistance, washing resistance and other properties of dyes can be adjusted to meet the needs of different fields for dyes.
In the field of organic synthesis, it is an important intermediate. The presence of chlorine atoms and chlorodiphenylmethyl in its structure endows it with active chemical properties and can participate in various chemical reactions, such as nucleophilic substitution reactions. Nucleophilic reagents can attack the carbon atoms connected to the chlorine atoms, causing the chlorine atoms to leave, and then form new carbon-heteroatom bonds. Through this, various complex organic compounds can be synthesized, which is of great significance in the fields of pharmaceutical chemistry and materials science.
At the level of drug development, using this as a starting material, molecular structures with specific biological activities can be constructed through multi-step reactions. Or its structure can be modified to make the synthesized drug molecules more suitable for the target, enhance the interaction with biomacromolecules, improve drug efficacy, reduce toxic and side effects. For example, the pharmacokinetics and pharmacodynamics of drugs can be optimized by adjusting the substituents on the benzene ring, changing the hydrophobicity and electron cloud distribution of the molecule.
In the field of materials science, it can be used to prepare functional polymer materials. By polymerizing with other monomers, this structure is introduced into the main chain or side chain of the polymer, giving the material unique properties. For example, because it contains a large benzene ring structure, it can improve the rigidity and thermal stability of the material; the presence of chlorine atoms can participate in subsequent reactions to modify the surface of the material to improve the adhesion and corrosion resistance of the material.
Furthermore, it is also used in the dye industry. Using its structure, specific chromophore compounds can be derived as synthetic precursors of new dyes. By modifying its structure, the color, light resistance, washing resistance and other properties of dyes can be adjusted to meet the needs of different fields for dyes.
What are the synthesis methods of 1-chloro-2- (chlorodiphenylmethyl) benzene
For 1-chloro-2 - (chlorodiphenylmethyl) benzene, the synthesis method has been known for a long time.
First take benzophenone as the beginning, and react with zinc amalgam and concentrated hydrochloric acid to perform Clemson reduction to obtain diphenylmethane. The method is also suitable for heating and reflux. After several hours, after the reaction is completed, the separation and purification steps are taken to obtain pure diphenylmethane.
Then, take diphenylmethane, use chlorine as the agent, light or heat to lead it to cause the reaction of free radical substitution. When exposed to light, chlorine molecules are excited by light and crack into chlorine free radicals, which interact with the hydrogen atom at the benzyl position in diphenylmethane to generate benzyl free radicals, and then interact with chlorine molecules to obtain chlorodiphenylmethane. This process requires controlling the speed of chlorine gas, the temperature and time of the reaction, in order to prevent the formation of polysubstituents.
In addition, take o-chlorotoluene as material, lithium-chlorobenzyl is obtained by the method of lithium lithium-butyl and other reagents. Then react with benzophenone to form an alkoxide first, and then acidify to obtain the corresponding alcohol. Finally, the alcohol is converted into 1-chloro-2 - (chlorodiphenylmethyl) benzene with chlorinated reagents, such as thionyl chloride, etc. In this path, the lithiation step needs to be at a low temperature, anhydrous and oxygen-free environment to prevent side reactions.
There is also a condensation reaction based on o-chlorobenzaldehyde and diphenylchloromethane under the catalysis of alkali. The base can be selected from sodium alcohol, etc., and reacted in an appropriate solvent, such as an alcohol solvent. After the reaction, the product can be purified by extraction, distillation, etc.
All synthesis methods have their own advantages and disadvantages, and they need to be selected according to the availability of raw materials, cost considerations, and the purity of the product.
First take benzophenone as the beginning, and react with zinc amalgam and concentrated hydrochloric acid to perform Clemson reduction to obtain diphenylmethane. The method is also suitable for heating and reflux. After several hours, after the reaction is completed, the separation and purification steps are taken to obtain pure diphenylmethane.
Then, take diphenylmethane, use chlorine as the agent, light or heat to lead it to cause the reaction of free radical substitution. When exposed to light, chlorine molecules are excited by light and crack into chlorine free radicals, which interact with the hydrogen atom at the benzyl position in diphenylmethane to generate benzyl free radicals, and then interact with chlorine molecules to obtain chlorodiphenylmethane. This process requires controlling the speed of chlorine gas, the temperature and time of the reaction, in order to prevent the formation of polysubstituents.
In addition, take o-chlorotoluene as material, lithium-chlorobenzyl is obtained by the method of lithium lithium-butyl and other reagents. Then react with benzophenone to form an alkoxide first, and then acidify to obtain the corresponding alcohol. Finally, the alcohol is converted into 1-chloro-2 - (chlorodiphenylmethyl) benzene with chlorinated reagents, such as thionyl chloride, etc. In this path, the lithiation step needs to be at a low temperature, anhydrous and oxygen-free environment to prevent side reactions.
There is also a condensation reaction based on o-chlorobenzaldehyde and diphenylchloromethane under the catalysis of alkali. The base can be selected from sodium alcohol, etc., and reacted in an appropriate solvent, such as an alcohol solvent. After the reaction, the product can be purified by extraction, distillation, etc.
All synthesis methods have their own advantages and disadvantages, and they need to be selected according to the availability of raw materials, cost considerations, and the purity of the product.
What are the precautions for 1-chloro-2- (chlorodiphenylmethyl) benzene during storage and transportation?
1-Chloro-2 - (chlorodiphenylmethyl) benzene. When storing and transporting this substance, many matters need to be paid attention to.
It is chemically active. When storing, first choose a cool, dry and well-ventilated place. Avoid high temperatures, open flames and strong oxidants. If it is heated or encountered by strong oxidants, it is easy to cause violent chemical reactions and cause the risk of explosion. The warehouse temperature should be controlled within a specific range to avoid excessive temperature changing the properties of the substance.
Packaging must be tight and reliable. Appropriate packaging materials, such as sealed metal drums or special plastic containers, should be used to prevent leakage. If the package is damaged, the substance comes into contact with air, moisture, etc., or deteriorates, and the leaked material or pollutes the environment, endangering the safety of personnel.
During transportation, the driving should be stable, avoid sudden braking and sharp turns, and prevent the package from being damaged due to vibration and collision. The means of transportation should be clean and dry, and no other chemicals should be left to react with it. In accordance with relevant regulations, clear hazard signs should also be posted to inform the transporter and surrounding people of the danger.
Furthermore, those who operate and come into contact with this substance should be equipped with suitable protective equipment, such as protective gloves, goggles, protective clothing, etc. If a leak is detected during storage or transportation, it should be dealt with immediately according to the emergency plan, evacuate personnel, isolate the site, and recover or clean up the leak with appropriate methods to avoid expanding the harm.
It is chemically active. When storing, first choose a cool, dry and well-ventilated place. Avoid high temperatures, open flames and strong oxidants. If it is heated or encountered by strong oxidants, it is easy to cause violent chemical reactions and cause the risk of explosion. The warehouse temperature should be controlled within a specific range to avoid excessive temperature changing the properties of the substance.
Packaging must be tight and reliable. Appropriate packaging materials, such as sealed metal drums or special plastic containers, should be used to prevent leakage. If the package is damaged, the substance comes into contact with air, moisture, etc., or deteriorates, and the leaked material or pollutes the environment, endangering the safety of personnel.
During transportation, the driving should be stable, avoid sudden braking and sharp turns, and prevent the package from being damaged due to vibration and collision. The means of transportation should be clean and dry, and no other chemicals should be left to react with it. In accordance with relevant regulations, clear hazard signs should also be posted to inform the transporter and surrounding people of the danger.
Furthermore, those who operate and come into contact with this substance should be equipped with suitable protective equipment, such as protective gloves, goggles, protective clothing, etc. If a leak is detected during storage or transportation, it should be dealt with immediately according to the emergency plan, evacuate personnel, isolate the site, and recover or clean up the leak with appropriate methods to avoid expanding the harm.
What are the effects of 1-chloro-2- (chlorodiphenylmethyl) benzene on the environment and human health?
1-Chloro-2 - (chlorodiphenylmethyl) benzene, this is an organic compound. The impact on the environment and human health has been explored by predecessors.
At the environmental end, if this substance is released into nature, it is difficult to be rapidly decomposed by microorganisms due to its chemical structure, or it may cause long-term residue. It may be adsorbed on soil particles, affecting soil quality, hindering plant root absorption of nutrients, resulting in poor plant growth. And it may enter the water body with precipitation runoff, polluting the water source and posing a threat to aquatic organisms. Long-term exposure of aquatic organisms to this substance may cause physiological disorders, such as affecting the reproduction and development of fish and reducing the population size.
As for human health, if people ingest this substance through breathing, diet or skin contact, it is very harmful. Inhalation of air containing this substance may irritate the respiratory tract, causing symptoms such as cough and asthma. Long-term inhalation may damage lung tissue and weaken respiratory function. If ingested orally, it may affect the digestive system, causing nausea, vomiting, abdominal pain, etc. And this substance may be potentially carcinogenic, long-term exposure may increase the risk of cancer. And because it can penetrate through the skin, direct contact with substances containing this substance may cause skin allergies, redness, swelling, and itching.
The ancients said: "The scourge of the husband often accumulates in the small." Although this chemical substance is not widely known, its potential harm to the environment and human health should not be underestimated. People should use products containing such substances with caution to prevent problems before they occur, protect the environment and their own health.
At the environmental end, if this substance is released into nature, it is difficult to be rapidly decomposed by microorganisms due to its chemical structure, or it may cause long-term residue. It may be adsorbed on soil particles, affecting soil quality, hindering plant root absorption of nutrients, resulting in poor plant growth. And it may enter the water body with precipitation runoff, polluting the water source and posing a threat to aquatic organisms. Long-term exposure of aquatic organisms to this substance may cause physiological disorders, such as affecting the reproduction and development of fish and reducing the population size.
As for human health, if people ingest this substance through breathing, diet or skin contact, it is very harmful. Inhalation of air containing this substance may irritate the respiratory tract, causing symptoms such as cough and asthma. Long-term inhalation may damage lung tissue and weaken respiratory function. If ingested orally, it may affect the digestive system, causing nausea, vomiting, abdominal pain, etc. And this substance may be potentially carcinogenic, long-term exposure may increase the risk of cancer. And because it can penetrate through the skin, direct contact with substances containing this substance may cause skin allergies, redness, swelling, and itching.
The ancients said: "The scourge of the husband often accumulates in the small." Although this chemical substance is not widely known, its potential harm to the environment and human health should not be underestimated. People should use products containing such substances with caution to prevent problems before they occur, protect the environment and their own health.
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