Linshang Chemical
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1-Chloro-2-(Chloromethyl)-Benzene
Linshang Chemical
|
HS Code |
798279 |
| Chemical Formula | C8H8Cl2 |
| Molar Mass | 175.055 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 221 - 223 °C |
| Melting Point | -22 °C |
| Density | 1.19 g/cm³ at 20 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Flash Point | 97 °C |
| Odor | Pungent odor |
As an accredited 1-Chloro-2-(Chloromethyl)-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 2 - (chloromethyl) - benzene in 500 - mL glass bottle, 1 unit. |
| Storage | 1 - Chloro - 2 - (chloromethyl) - benzene should be stored in a cool, well - ventilated area, away from heat sources and open flames as it is flammable. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions. The storage area should be dry to prevent hydrolysis. |
| Shipping | 1 - chloro - 2 - (chloromethyl) - benzene is a hazardous chemical. Shipping must comply with strict regulations. It should be packaged in appropriate, leak - proof containers, labeled clearly, and transported by carriers licensed for hazardous materials. |
Competitive 1-Chloro-2-(Chloromethyl)-Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 1-Chloro-2-(Chloromethyl)-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 1-chloro-2 - (chloromethyl) benzene?
1 + -Deuterium-2- (deuterium methyl) naphthalene is one of the organic compounds. Its chemical properties are quite interesting, and I will describe them in detail for you.
First of all, its structure is based on naphthalene ring. The naphthalene ring has a planar structure with conjugated double bonds, and the stability is quite high. On the naphthalene ring, there are deuterium atoms and deuterium methyl substitutions. Deuterium, the isotope of hydrogen, has more neutrons in its nucleus, so its mass is larger than that of hydrogen. The particularity of this structure has a profound impact on its chemical properties.
When it comes to reactivity, due to the similar chemical properties of deuterium and hydrogen, the mass difference causes significant kinetic isotope effects. In many reactions, it is more difficult to break the carbon-deuterium bond than the carbon-hydrogen bond, and the reaction rate is also slower. For example, in the electrophilic substitution reaction, although the reaction check point still follows the positioning rule of the naphthalene ring, that is, it mainly occurs at the alpha position, but due to the presence of deuterium, the reaction rate is slightly slower than that of the unsubstituted naphthalene.
Furthermore, its stability is also noteworthy. Due to the heavier deuterium atom, the formed carbon-deuterium bond is slightly shorter and stronger than the carbon-hydrogen bond, which improves the overall stability of the molecule. In terms of thermal stability, it can withstand higher temperatures without decomposing than the carbon-hydrogen bond analogs.
and its solubility, generally similar to naphthalene compounds, because the molecule has a large non-polar part, the solubility is better in non-polar organic solvents such as benzene, toluene, etc., but it is difficult to dissolve in polar solvents such as water.
In redox reactions, it also exhibits unique properties. Due to its structure, it can participate in the reaction as an electron receptor or donor, and due to the influence of deuterium, the reaction mechanism may be slightly different from conventional naphthalene derivatives.
The chemical properties of this 1 + -deuterium-2- (deuteromethyl) naphthalene are derived from its special structure. In the field of organic chemistry, it is of great significance for exploring the reaction mechanism and developing special materials.
First of all, its structure is based on naphthalene ring. The naphthalene ring has a planar structure with conjugated double bonds, and the stability is quite high. On the naphthalene ring, there are deuterium atoms and deuterium methyl substitutions. Deuterium, the isotope of hydrogen, has more neutrons in its nucleus, so its mass is larger than that of hydrogen. The particularity of this structure has a profound impact on its chemical properties.
When it comes to reactivity, due to the similar chemical properties of deuterium and hydrogen, the mass difference causes significant kinetic isotope effects. In many reactions, it is more difficult to break the carbon-deuterium bond than the carbon-hydrogen bond, and the reaction rate is also slower. For example, in the electrophilic substitution reaction, although the reaction check point still follows the positioning rule of the naphthalene ring, that is, it mainly occurs at the alpha position, but due to the presence of deuterium, the reaction rate is slightly slower than that of the unsubstituted naphthalene.
Furthermore, its stability is also noteworthy. Due to the heavier deuterium atom, the formed carbon-deuterium bond is slightly shorter and stronger than the carbon-hydrogen bond, which improves the overall stability of the molecule. In terms of thermal stability, it can withstand higher temperatures without decomposing than the carbon-hydrogen bond analogs.
and its solubility, generally similar to naphthalene compounds, because the molecule has a large non-polar part, the solubility is better in non-polar organic solvents such as benzene, toluene, etc., but it is difficult to dissolve in polar solvents such as water.
In redox reactions, it also exhibits unique properties. Due to its structure, it can participate in the reaction as an electron receptor or donor, and due to the influence of deuterium, the reaction mechanism may be slightly different from conventional naphthalene derivatives.
The chemical properties of this 1 + -deuterium-2- (deuteromethyl) naphthalene are derived from its special structure. In the field of organic chemistry, it is of great significance for exploring the reaction mechanism and developing special materials.
What are some common uses of 1-chloro-2 - (chloromethyl) benzene?
1 + -Alkane-2- (alkyl methyl) benzene has a wide range of uses.
First, in the field of fragrances, it is often used as a raw material. Because of its unique smell, it can be skillfully prepared by perfumers and can be used in the manufacture of various perfumes, air fresheners and other fragrance products. This material can give the aroma a unique charm, or fresh and elegant, or rich and charming, adding a different style to the fragrance.
Second, in the pharmaceutical and chemical industry, it also plays an important role. It can be used as an intermediate for the synthesis of many drugs. With the help of organic synthesis methods, complex drug molecular structures are constructed on the basis of them, which are used to develop drugs for the treatment of various diseases, such as antibacterial, anti-inflammatory and other drugs.
Third, in the coating industry, it plays the role of a solvent. Because of its good solubility, it can dissolve a variety of resin and other film-forming substances, making it easier to coat evenly during construction, forming a flat and smooth coating, improving the performance and appearance quality of coatings, and is widely used in furniture paints, automotive paints and other coatings.
Fourth, in the field of organic synthesis, it is an important basic raw material. Through a series of chemical reactions, such as substitution reactions, addition reactions, etc., a wide range of organic compounds with different functions and structures can be derived, providing an important material foundation for the development of organic synthetic chemistry and enabling the synthesis of new materials and chemicals.
First, in the field of fragrances, it is often used as a raw material. Because of its unique smell, it can be skillfully prepared by perfumers and can be used in the manufacture of various perfumes, air fresheners and other fragrance products. This material can give the aroma a unique charm, or fresh and elegant, or rich and charming, adding a different style to the fragrance.
Second, in the pharmaceutical and chemical industry, it also plays an important role. It can be used as an intermediate for the synthesis of many drugs. With the help of organic synthesis methods, complex drug molecular structures are constructed on the basis of them, which are used to develop drugs for the treatment of various diseases, such as antibacterial, anti-inflammatory and other drugs.
Third, in the coating industry, it plays the role of a solvent. Because of its good solubility, it can dissolve a variety of resin and other film-forming substances, making it easier to coat evenly during construction, forming a flat and smooth coating, improving the performance and appearance quality of coatings, and is widely used in furniture paints, automotive paints and other coatings.
Fourth, in the field of organic synthesis, it is an important basic raw material. Through a series of chemical reactions, such as substitution reactions, addition reactions, etc., a wide range of organic compounds with different functions and structures can be derived, providing an important material foundation for the development of organic synthetic chemistry and enabling the synthesis of new materials and chemicals.
What are the methods for preparing 1-chloro-2 - (chloromethyl) benzene?
There are various ways to prepare 1-bromo-2- (bromomethyl) naphthalene, which are described as follows:
First, use 2-methylnaphthalene as the starting material, and first brominate with bromine under appropriate conditions. This reaction requires attention to the reaction temperature, bromine dosage and reaction time. At low temperatures, light or in the presence of initiators, the methyl of 2-methylnaphthalene can be replaced by bromine atoms to generate 2- (bromomethyl) naphthalene. Then, under the catalysis of 2 - (bromomethyl) naphthalene and bromine in a specific catalyst, such as iron powder or iron tribromide, an electrophilic substitution reaction occurs at a specific position (usually 1 - position) on the naphthalene ring to obtain 1 - bromomethyl - (bromomethyl) naphthalene. This path step is slightly more complicated, but the raw material 2 - methylnaphthalene is relatively easy to obtain, and the reaction conditions of each step are also easier to control.
Second, naphthalene is used as the starting material. Schilling naphthalene and halogenated alkanes (such as bromomethane) are catalyzed by Lewis acid (such as aluminum trichloride) to undergo Fu-gram alkylation to obtain 2 - methylnaphthalene. The next step is similar to the following steps with 2-methylnaphthalene as the starting material, that is, bromination at the methyl first, and then bromination at the 1-position of the naphthalene ring, and finally obtain 1-bromo-2 - (bromomethyl) naphthalene. Although this approach has many steps, naphthalene is a common basic raw material, and the cost may be advantageous. The alkylation reaction of Weifu-gram requires strict anhydrous conditions, and the catalyst dosage, reaction temperature and other factors have a great influence on the selectivity of the product.
Third, some special reagents can be considered for reaction with naphthalene derivatives. For example, with a specific bromine-containing reagent, in an appropriate reaction system, through multi-step conversion, the preparation of 1-bromo-2- (bromomethyl) naphthalene can be achieved. This method may involve some novel reaction mechanisms and reagents. Although the steps may be reduced, the reaction conditions are strict, and the relevant reagents may not be easily available, and the cost is high. The application in actual production may be limited. However, in laboratory research, it may be the direction to explore new synthesis routes.
All kinds of production methods have their own advantages and disadvantages. In actual operation, it is necessary to comprehensively weigh various factors such as the availability of raw materials, cost considerations, the ease of control of reaction conditions, and the purity requirements of the target product, and choose the appropriate method.
First, use 2-methylnaphthalene as the starting material, and first brominate with bromine under appropriate conditions. This reaction requires attention to the reaction temperature, bromine dosage and reaction time. At low temperatures, light or in the presence of initiators, the methyl of 2-methylnaphthalene can be replaced by bromine atoms to generate 2- (bromomethyl) naphthalene. Then, under the catalysis of 2 - (bromomethyl) naphthalene and bromine in a specific catalyst, such as iron powder or iron tribromide, an electrophilic substitution reaction occurs at a specific position (usually 1 - position) on the naphthalene ring to obtain 1 - bromomethyl - (bromomethyl) naphthalene. This path step is slightly more complicated, but the raw material 2 - methylnaphthalene is relatively easy to obtain, and the reaction conditions of each step are also easier to control.
Second, naphthalene is used as the starting material. Schilling naphthalene and halogenated alkanes (such as bromomethane) are catalyzed by Lewis acid (such as aluminum trichloride) to undergo Fu-gram alkylation to obtain 2 - methylnaphthalene. The next step is similar to the following steps with 2-methylnaphthalene as the starting material, that is, bromination at the methyl first, and then bromination at the 1-position of the naphthalene ring, and finally obtain 1-bromo-2 - (bromomethyl) naphthalene. Although this approach has many steps, naphthalene is a common basic raw material, and the cost may be advantageous. The alkylation reaction of Weifu-gram requires strict anhydrous conditions, and the catalyst dosage, reaction temperature and other factors have a great influence on the selectivity of the product.
Third, some special reagents can be considered for reaction with naphthalene derivatives. For example, with a specific bromine-containing reagent, in an appropriate reaction system, through multi-step conversion, the preparation of 1-bromo-2- (bromomethyl) naphthalene can be achieved. This method may involve some novel reaction mechanisms and reagents. Although the steps may be reduced, the reaction conditions are strict, and the relevant reagents may not be easily available, and the cost is high. The application in actual production may be limited. However, in laboratory research, it may be the direction to explore new synthesis routes.
All kinds of production methods have their own advantages and disadvantages. In actual operation, it is necessary to comprehensively weigh various factors such as the availability of raw materials, cost considerations, the ease of control of reaction conditions, and the purity requirements of the target product, and choose the appropriate method.
What are the precautions for storing and transporting 1-chloro-2 - (chloromethyl) benzene?
For 1 + -alkane-2- (alkyl methyl) ethers, there are many things to pay attention to when storing and transporting.
These substances are flammable, so when storing, they should be kept away from fire and heat sources, and placed in a well-ventilated place. If stored in a closed space with poor ventilation, once leaked, combustible gases will accumulate, and in case of open fire or static electricity, it is easy to cause the danger of explosion. In the warehouse, fireworks should also be strictly prohibited, and complete fire protection facilities, such as fire extinguishers, fire sand, etc. should be equipped for emergencies.
When transporting, the vehicles used must comply with the specifications for transporting hazardous chemicals. Vehicles need to have reliable grounding devices to prevent static electricity from accumulating and generating sparks. Drivers and escorts should be professionally trained to be familiar with the dangerous characteristics of such substances and emergency disposal methods. During transportation, vehicles should be avoided from violent bumps and collisions to prevent material leakage caused by damage to the container.
In addition, 1 + -alkane-2- (alkyl methyl) ether may be toxic to the human body to a certain extent. Obvious warning signs should be set up in storage places to remind personnel to pay attention to protection. When operating, operators should wear appropriate protective equipment, such as gas masks, protective gloves, etc., to avoid contact with or inhalation of harmful substances and endanger health. During transportation, if a leak occurs, surrounding personnel should be quickly evacuated to avoid contact with the leak, and effective measures should be taken to plug and clean up the leak to prevent the spread of pollution.
In addition, whether it is storage or transportation, relevant regulations and standards should be strictly followed. Detailed records of storage quantity, warehousing time, transportation route, time and other information for traceability and supervision. In this way, the safety of 1 + -alkane-2- (alkyl methyl) ether during storage and transportation can be guaranteed.
These substances are flammable, so when storing, they should be kept away from fire and heat sources, and placed in a well-ventilated place. If stored in a closed space with poor ventilation, once leaked, combustible gases will accumulate, and in case of open fire or static electricity, it is easy to cause the danger of explosion. In the warehouse, fireworks should also be strictly prohibited, and complete fire protection facilities, such as fire extinguishers, fire sand, etc. should be equipped for emergencies.
When transporting, the vehicles used must comply with the specifications for transporting hazardous chemicals. Vehicles need to have reliable grounding devices to prevent static electricity from accumulating and generating sparks. Drivers and escorts should be professionally trained to be familiar with the dangerous characteristics of such substances and emergency disposal methods. During transportation, vehicles should be avoided from violent bumps and collisions to prevent material leakage caused by damage to the container.
In addition, 1 + -alkane-2- (alkyl methyl) ether may be toxic to the human body to a certain extent. Obvious warning signs should be set up in storage places to remind personnel to pay attention to protection. When operating, operators should wear appropriate protective equipment, such as gas masks, protective gloves, etc., to avoid contact with or inhalation of harmful substances and endanger health. During transportation, if a leak occurs, surrounding personnel should be quickly evacuated to avoid contact with the leak, and effective measures should be taken to plug and clean up the leak to prevent the spread of pollution.
In addition, whether it is storage or transportation, relevant regulations and standards should be strictly followed. Detailed records of storage quantity, warehousing time, transportation route, time and other information for traceability and supervision. In this way, the safety of 1 + -alkane-2- (alkyl methyl) ether during storage and transportation can be guaranteed.
What are the effects of 1-chloro-2 - (chloromethyl) benzene on the environment and human health?
1 + -Alkane-2- (alkyl methyl) ether This substance has an impact on both the environment and human health.
At the environmental end, it evaporates into the atmosphere and can participate in photochemical reactions. Under sunlight exposure, it interacts with nitrogen oxides and other secondary pollutants, resulting in ozone and other secondary pollutants. This ozone is not the ozone that protects the earth in the stratosphere, but the harmful ozone near the ground, which will cause air quality to decline, form photochemical smog, reduce visibility, and cause trouble to the ecological environment and human travel. In addition, some alkyl ethers degrade slowly in the environment and will accumulate in soil, water and other media, which may affect the structure and function of soil microbial communities, interfere with the material circulation and energy conversion of soil ecosystems; in water, it may affect the survival and reproduction of aquatic organisms, and pose a threat to the balance of aquatic ecosystems.
As for human health, inhalation of this substance through the respiratory tract or skin contact may cause many adverse conditions. It may have irritating effects on the respiratory tract, causing symptoms such as cough, asthma, and poor breathing, especially for people with more sensitive respiratory tracts, such as asthma patients. And through skin contact, it may cause skin problems such as skin allergies, itching, redness, and swelling. Long-term exposure may also affect the nervous system, causing dizziness, fatigue, memory loss and other phenomena. What's more, some studies suggest that it may have potential carcinogenicity. Although the relevant conclusions are not completely conclusive, it is enough to raise people's attention to its health risks.
At the environmental end, it evaporates into the atmosphere and can participate in photochemical reactions. Under sunlight exposure, it interacts with nitrogen oxides and other secondary pollutants, resulting in ozone and other secondary pollutants. This ozone is not the ozone that protects the earth in the stratosphere, but the harmful ozone near the ground, which will cause air quality to decline, form photochemical smog, reduce visibility, and cause trouble to the ecological environment and human travel. In addition, some alkyl ethers degrade slowly in the environment and will accumulate in soil, water and other media, which may affect the structure and function of soil microbial communities, interfere with the material circulation and energy conversion of soil ecosystems; in water, it may affect the survival and reproduction of aquatic organisms, and pose a threat to the balance of aquatic ecosystems.
As for human health, inhalation of this substance through the respiratory tract or skin contact may cause many adverse conditions. It may have irritating effects on the respiratory tract, causing symptoms such as cough, asthma, and poor breathing, especially for people with more sensitive respiratory tracts, such as asthma patients. And through skin contact, it may cause skin problems such as skin allergies, itching, redness, and swelling. Long-term exposure may also affect the nervous system, causing dizziness, fatigue, memory loss and other phenomena. What's more, some studies suggest that it may have potential carcinogenicity. Although the relevant conclusions are not completely conclusive, it is enough to raise people's attention to its health risks.
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