1-Chloro-2-Ethylbenzene
Linshang Chemical
HS Code |
487767 |
Chemical Formula | C8H9Cl |
Molecular Weight | 140.61 g/mol |
Appearance | Colorless to light yellow liquid |
Odor | Aromatic odor |
Density | 1.07 g/cm³ |
Boiling Point | 199 - 201 °C |
Melting Point | -43 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
Flash Point | 75 °C |
Vapor Pressure | 0.23 mmHg at 25 °C |
Refractive Index | 1.543 - 1.545 |
As an accredited 1-Chloro-2-Ethylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 -chloro - 2 -ethylbenzene in 500 mL glass bottle, well - sealed for chemical storage. |
Storage | 1 - chloro - 2 - ethylbenzene should be stored in a cool, well - ventilated area away from direct sunlight. Keep it in a tightly sealed container made of suitable materials like steel or high - density polyethylene to prevent leakage. Store it separate from oxidizing agents, acids, and bases. Adhere to proper safety regulations to avoid potential fire, explosion, or chemical reaction risks. |
Shipping | 1 - chloro - 2 - ethylbenzene is shipped in tightly sealed, corrosion - resistant containers. It must be transported in accordance with hazardous chemical regulations, ensuring proper labeling and safety measures during transit to prevent leakage and ensure safety. |
Competitive 1-Chloro-2-Ethylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 1-Chloro-2-Ethylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Nucleophilic substitution reaction
Its chlorine atom activity is quite good, and it is prone to nucleophilic substitution when encountering nucleophilic reagents. Taking sodium hydroxide aqueous solution as an example, under appropriate conditions, chlorine atoms can be replaced by hydroxyl groups to generate 2-ethylphenol. This is because hydroxyl groups have stronger nucleophilicity than chloride ions. Hydroxyl groups attack the carbon atoms attached to chlorine atoms, and chloride ions leave to achieve substitution. The reaction formula is as follows:
1-chloro-2-ethylbenzene + NaOH → 2-ethylphenol + NaCl
electrophilic substitution reaction
The benzene ring is rich in electrons and is susceptible to electrophilic attack, and electrophilic substitution occurs. If co-heated with mixed acid (concentrated sulfuric acid and concentrated nitric acid mixture), nitro (- NO ³) will replace the hydrogen atom on the benzene ring. Because ethyl is an ortho-and para-site group, nitro mainly enters the ethyl ortho-and para-sites to generate 2-ethyl-4-nitrochlorobenzene and 2-ethyl-6-nitrochlorobenzene. During the reaction, the mixed acid produces the electrophilic reagent nitroyl positive ion (NO 2), which attacks the benzene ring to form an intermediate, and then loses protons to complete the reaction.
Elimination Reaction
In a strong alkali alcohol solution, 1-chloro-2-ethylbenzene can be eliminated. The hydrogen atom on the chlorine atom and the ortho-carbon atom is removed under the action of a strong base to form unsaturated olefins. For example, it reacts with a sodium ethanol solution to form 1-phenyl-1-propylene. This reaction requires an appropriate temperature. The strong base captures the ortho-hydrogen atom, the electron pair is transferred to form a carbon-carbon double bond, and the chloride ion leaves at the same time.
Oxidation Reaction
The side chain ethyl group of the benzene ring can be ox If acidic potassium permanganate solution is used as oxidant, ethyl can be gradually oxidized to carboxyl group to form 2-chlorobenzoic acid. During the reaction, the valence of manganese in potassium permanganate decreases, and the valence of ethyl carbon atoms increases, realizing the oxidation process.
Radical Reaction
Under light or high temperature, the hydrogen atom on the ethyl group of the 1-chloro-2-ethylbenzene side chain can undergo radical substitution. If it is irradiated with chlorine, the chlorine radical will capture the hydrogen atom on the ethyl group to form a chlorination product. The generated free radical intermediate can further react with chlorine to form products with different degrees of chlorination.
This compound is widely used in the field of organic synthesis. First, it can be used as a key intermediate. For example, in the preparation of aromatic compounds with specific structures, by virtue of the activity of chlorine atoms and ethyl groups, it can introduce other functional groups through many chemical reactions, such as nucleophilic substitution reactions. When reacting with substances containing nucleophiles, chlorine atoms can be replaced by other groups to construct more complex organic molecules, which is very important for the preparation of new drug molecules in the field of medicinal chemistry.
Second, it is also used in the field of materials science. It can participate in the polymerization reaction as a monomer or modifier to adjust the properties of the polymer. Its molecular structure contains aromatic rings and alkyl groups, which can endow the polymer with specific physical and chemical properties, such as improving the heat resistance and mechanical properties of the polymer, which is helpful in the preparation of high-performance engineering plastics, special coatings, etc.
Third, it can also play a role in the fragrance industry. Because of its unique aromatic odor, after appropriate chemical modification and preparation, it can be used to prepare certain flavors and fragrances to add a unique aroma to the product.
Fourth, in the study of new catalysts or catalytic reaction mechanisms, 1-chloro-2-ethylbenzene can serve as a model substrate. By studying its reaction behavior under different catalytic conditions, we can gain a deeper understanding of the process and mechanism of catalytic reactions, and help develop more efficient and selective catalytic systems.
First, it can be obtained from o-ethylaniline through diazotization and Sandmeier reaction. First, make o-ethylaniline and sodium nitrite react at low temperature in hydrochloric acid solution to form diazonium salts. This step needs to be carefully controlled to prevent the decomposition of diazonium salts, generally at 0-5 ° C. Then add the hydrochloric acid solution of cuprous chloride, the diazonium group is replaced by the chlorine atom, and then 1-chloro-2-ethylbenzene is obtained. This reaction condition is mild and the yield is also good. However, the preparation of cuprous chloride is slightly complicated, and the toxic sodium nitrite is required. Extra care must be taken in the operation.
Second, using o-chloroacetophenone as raw material, it can be prepared by reduction reaction. Commonly used reducing agents such as zinc amalgam and concentrated hydrochloric acid, this is the Clemson reduction method. The o-chloroacetophenone is co-heated with zinc amalgam and concentrated hydrochloric acid, and the carbonyl group is reduced to methylene to obtain the target product. However, this reaction needs to be carried out under strong acidic conditions, which seriously corrodes the equipment, and the post-treatment is more complicated.
Third, it is prepared by the addition reaction of styrene and hydrogen chloride. Under the action of a catalyst, such as peroxide, styrene and hydrogen chloride undergo a free radical addition reaction. Hydrogen atoms are added to double-bonded carbon atoms with less hydrogen, and chlorine atoms are added to double-bonded carbon atoms with more hydrogen to generate 1-chloro-2-ethylbenzene. This method is easy to obtain raw materials and is relatively simple to operate, but it is necessary to control the reaction conditions to ensure the selectivity of the addition reaction.
Fourth, using o-chlorotoluene as a raw material, in the presence of light or initiator, it undergoes a Fu-gram alkylation reaction with chloroethane. This reaction requires Lewis acid such as anhydrous aluminum trichloride as a catalyst. During the reaction, attention should be paid to controlling the reaction temperature and the ratio of raw materials to avoid the occurrence of polyalkylation side reactions. After the reaction is completed, 1-chloro-2-ethylbenzene can be obtained through separation and purification.
When storing, choose a suitable place first. It must be placed in a cool and ventilated place, so avoid hot topics and fire species. Because the substance encounters open flames and hot topics, it is very easy to burn, causing the risk of fire. And the warehouse temperature should not be too high, and it should be controlled within a specific range to prevent its volatilization from intensifying due to excessive temperature, or triggering other chemical reactions.
Furthermore, it should be stored separately from oxidants, acids, bases and other substances. Due to its lively chemical properties, contact with various such substances can easily cause chemical reactions, or cause serious accidents such as explosions and leaks. At the same time, obvious warning signs must be set up in the storage area to make everyone aware of the danger and prevent it.
The transportation process should not be ignored. The transportation vehicle must meet safety standards and be equipped with corresponding fire fighting equipment and leakage emergency treatment equipment. When loading, be careful to avoid collisions and heavy pressure to prevent material leakage due to damaged packaging. During transportation, drivers and escorts must pay close attention to the condition of the vehicle and the condition of the goods, and must not leave the post without authorization. In case of emergencies, such as leaks, emergency measures should be taken immediately, surrounding personnel should be evacuated, and relevant departments should be promptly reported.
In terms of packaging, there are also strict requirements. Packaging materials that meet safety standards must be used to ensure a good seal to prevent leakage. And the name of the chemical, hazardous characteristics, emergency treatment methods and other information should be clearly marked on the outside of the package, so that relevant personnel can identify and respond.
In short, the storage and transportation of 1-chloro-2-ethylbenzene is a matter of safety, and it must be done in accordance with relevant regulations and operating procedures to ensure that nothing is wrong.
Let's talk about its impact on the environment first. If 1-chloro-2-ethylbenzene is released in nature, in the atmosphere, it may participate in photochemical reactions, affect air quality, cause smog and other adverse phenomena. It is difficult to degrade in water, and can accumulate in aquatic organisms, destroying the balance of aquatic ecosystems. And it may be transmitted through the food chain, which also affects higher nutrient level organisms. In the soil, it may hinder the normal activities of soil microorganisms, thereby affecting soil fertility and structure.
As for the impact on human health. If people ingest 1-chloro-2-ethylbenzene through breathing, skin contact or accidental ingestion, it is quite harmful. In the respiratory system, it can cause symptoms such as cough, asthma, breathing difficulties, long-term exposure, or damage to lung function. Contact with the skin can cause skin irritation, redness, swelling, itching, and even allergic reactions. If ingested accidentally, it can irritate the gastrointestinal tract, causing nausea, vomiting, abdominal pain, etc. In more serious cases, this compound may be potentially carcinogenic. Long-term exposure increases the risk of cancer, and may affect the nervous system, causing headaches, dizziness, fatigue, memory loss and other neurological disorders.
From this perspective, 1-chloro-2-ethylbenzene poses a significant threat to the environment and human health. During its production, use, and disposal, it is necessary to exercise caution and adopt proper protection and handling methods to reduce its harm.
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In the process of petroleum refining, it can be used to refine, remove sulfur, nitrogen, oxygen, etc. from the oil, and improve the oil product to make it more in line with the requirements of the warranty. In addition, it can be used for cleaning energy, prospect. Burning raw water, emitting pollutants, in the fuel pool, the oxygen reaction can directly reduce the energy, and provide power for transportation, ships, etc., to help the low-carbon transportation industry.
to 2-ethylbenzene, which also has important uses in engineering. Often used in the synthesis of important products. It can be reversed from a series, and it can be used for a variety of useful products. For example, it can be oxidized to form a carboxylic acid of the phase. This carboxylic acid can be used in the manufacture of plasticizers, which can improve the flexibility and processability of plastics. It is widely used in plastic products, such as the production of polyvinyl chloride (PVC) products. In addition, 2-ethylbenzene can also be used in synthetic fragrances. The fragrance industry provides an important raw material to give each product a pleasant taste. In some special chemical processes, 2-ethylbenzene can be used as a solution because of its unique properties. Certain substances have good solubility properties, which can help to complete some chemical reactions or improvement processes.
Looking at its properties, under normal temperature and pressure, 1-bromo-2-methylpropane is often a colorless and transparent liquid, with a relatively pure texture and no impurities visible to the naked eye. Its odor has a special volatile odor. Although it is not strong and pungent, it is also different from common odorless substances. To a certain extent, this odor can be used as one of its physical characteristics to identify.
When it comes to density, the density of 1-bromo-2-methylpropane is greater than that of water. If it is placed in a container with water, it can be clearly seen that it sinks to the bottom of the water. This is due to factors such as intermolecular forces and atomic composition, which make its unit volume mass greater than that of water.
As for the melting point and boiling point, the melting point of 1-bromo-2-methylpropane is lower, about -119 ° C. At this temperature, it changes from liquid to solid. The boiling point is relatively moderate, about 69-72 ° C. When the temperature rises to the boiling point, the substance rapidly converts from liquid to gaseous, causing violent vaporization.
In terms of solubility, 1-bromo-2-methylpropane is insoluble in water, because water is a polar molecule, while 1-bromo-2-methylpropane has a weaker polarity. According to the principle of "similar miscibility", the two are not easy to dissolve each other. However, it is soluble in many organic solvents, such as ethanol, ether, etc. In these organic solvents, it can mix well with solvent molecules through intermolecular forces, showing good solubility.
In addition, 1-bromo-2-methylpropane has a certain volatility. In an open environment, its molecules are constantly moving and gradually evaporate from liquid to gaseous, resulting in a decrease in mass. This volatility is also one of its important physical properties.
is the most important element in the universe, showing color, odor, and taste. Its chemical activity, under normal conditions, is determined by the phase, and in case of high temperature, open flame or catalysis, it can generate a lot of biochemical reactions. For example, when oxygen is mixed, it will explode immediately to generate water, and this reaction will release a lot of energy. Equation: $2H_ {2} + O_ {2}\ stackrel {}{=\!=\!=} 2H_ {2} O $. Moreover, it is original, capable of generating gold oxides, such as oxidation reaction: $H_ {2} + CuO\ stackrel {\ Delta }{=\!=\!=} Cu + H_ {2} O $, which is commonly used in metallurgical engineering.
As for 2-ethylbenzene, it has a chemical compound, which is aromatic. The existence of benzene makes it have a special quality. Due to the formation of a common system of benzene's π daughter, the daughter can be effectively localized, causing its chemical phase to be determined, and it is not easy to generate addition and inverse, but to be substituted and inverse. For example, under the appropriate catalysis and reaction, it can be substituted and reversed by elements, sulfuric acid, etc. However, the introduction of ethyl group makes 2-ethylbenzene have a certain activity and can be oxidized. For example, under the action of oxidation, ethyl can be oxidized to carboxyl groups to form benzoic acid derivatives.
Therefore, the chemical activity of 2-ethylbenzene and 2-ethylbenzene are determined, but both are different due to the chemical activity of the product.
First of all, the quality of the raw materials is of paramount importance. The starting material used must have a high degree of quality. If there is a problem, it will be difficult to reverse the road or produce differences, and the quality of the product will also be guaranteed. If the raw material is obtained, add more and more, according to the appropriate method, so that it can be used until the required degree.
The second time, the control of the reverse parts should not be lost. Those who are good, the reverse is also good. If the temperature is high, the reaction may be out of control, and the side reaction may occur, so that the rate of reaction is low; if the temperature is low, the reaction may be low, or even low. Therefore, according to the characteristics of the reaction, the degree of reaction can be precisely controlled, and the water bath, oil bath and other methods can be used to make the reaction rate fixed at the required value. In addition, the reaction rate is also controlled, the reaction rate is insufficient, the reaction is not completed, and the reaction rate is not high; the reaction rate, or the decomposition of the catalyst, is also not suitable.
The amount of catalysis used is also low. The combined catalysis can promote the reaction rate and reduce the activation energy of the reaction. However, the amount of catalysis can be controlled by more or more reaction speed, and the catalytic effect is not good. It is necessary to explore and obtain the appropriate dosage in order to make the reaction efficient.
Furthermore, pay attention to the environment of the reaction. If the reaction is empty and moisture sensitive, it needs to be operated in the environment of water and oxygen. Inert protection can be used, such as nitrogen and nitrogen, which are used to isolate the outside world, so as to prevent raw materials and materials from being exposed to oxygen and water vapor in the air.
The process of operation, especially careful. Adding high temperature, the rate is appropriate, and the mixture is uniform, so that the reaction is fully mixed, and the local temperature is high, and it is easy to lead to secondary reactions. In the same way, in the case of toxic and harmful substances produced in the reaction, the javelin must do a good job of tail treatment to meet the requirements of protection and ensure the safety of the operator.
In other words, the use of 1-bromo-2-ethylbenzene should be carefully considered and operated in a strict manner in order to make the reaction profitable and obtain high-quality substances.
If it is used rationally, it will burn raw water and cause harmful substances to be polluted in the environment. As for ethylbenzene, it has chemical substances.
As for ethylbenzene, this material has the properties of the environment, and it can be reacted to by photochemical reactions. In the presence of light, nitrogen oxides, etc., it can promote the formation of photochemical emissions, which can reduce energy efficiency and contain a lot of harmful substances, such as ozone, etc., which does not affect the respiratory system of humans and also harms the growth of plants. Furthermore, ethylbenzene is used in soil or water, because it is soluble in water, it can penetrate and accumulate in the soil, affect the fertility of the soil, and damage the breeding of plant roots. In water, it can affect the survival of aquatic organisms. Because of its toxicity, it can cause diseases and deaths of aquatic organisms, and break the balance of aquatic life.
Of course, it is beneficial to the environment and contains many elements of color. If ethylbenzene is not controlled, it will cause harm to the environment, damage the environment, and endanger the safety of food.

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