Linshang Chemical
PRODUCTS
1-Chloro-2-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene
Linshang Chemical
|
HS Code |
774584 |
| Chemical Formula | C7H2ClF4NO2 |
| Molecular Weight | 245.54 |
As an accredited 1-Chloro-2-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 2 - fluoro - 3 - nitro - 5 - (trifluoromethyl)benzene in 500g sealed glass bottle packaging. |
| Storage | 1 - Chloro - 2 - fluoro - 3 - nitro - 5 - (trifluoromethyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials. Store it separately from incompatible substances like oxidizing agents, reducing agents, and bases to prevent chemical reactions. |
| Shipping | 1 - Chloro - 2 - fluoro - 3 - nitro - 5 - (trifluoromethyl)benzene is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring safe transportation to prevent any leakage or incidents. |
Competitive 1-Chloro-2-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Chloro-2-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene in China?
As a trusted 1-Chloro-2-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Chloro-2-Fluoro-3-Nitro-5-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene?
1-Chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene, this compound is widely used in various fields of chemical industry.
In the field of organic synthesis, it is often used as a key intermediate. Because its molecular structure is rich in chlorine, fluorine, nitro and trifluoromethyl and other functional groups, each functional group has unique reactivity, and can be derived from a wide range of organic compounds through many chemical reactions, such as nucleophilic substitution, reduction, coupling, etc. For example, chlorine atoms can be replaced by nucleophiles under appropriate conditions, thus introducing other functional groups to lay the foundation for the construction of complex organic molecules; nitro groups can be converted into amino groups through reduction reactions to expand the reaction path of compounds, and then synthesize organic molecules with specific biological activities or functions. In the field of medicinal chemistry, it may be used to create new drug molecules.
In the field of materials science, 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene also has its uses. Due to its fluorine atoms and trifluoromethyl groups, it can endow materials with unique physical and chemical properties. Fluorine atoms have high electronegativity, which can enhance intermolecular forces, improve material stability and durability; the introduction of trifluoromethyl may improve the properties of materials such as chemical corrosion resistance, low surface energy and hydrophobicity. Therefore, it can be used to prepare high-performance coatings, special plastics or functional polymer materials, such as the preparation of coatings with good weather resistance, for outdoor facilities protection, which can make them resist harsh environmental erosion for a long time.
Furthermore, in the field of agricultural chemistry, it may also make a difference. Some organic compounds containing fluorine and nitro groups show certain biological activities, or can be used to develop new pesticides. 1-Chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene can be used as an intermediate, or through appropriate chemical modification, to create a pesticide product with efficient control effect on specific pests and diseases, and because of the presence of fluorine atoms, it may improve the environmental stability and biological activity of pesticides, reduce the dosage, and reduce the negative impact on the environment.
In the field of organic synthesis, it is often used as a key intermediate. Because its molecular structure is rich in chlorine, fluorine, nitro and trifluoromethyl and other functional groups, each functional group has unique reactivity, and can be derived from a wide range of organic compounds through many chemical reactions, such as nucleophilic substitution, reduction, coupling, etc. For example, chlorine atoms can be replaced by nucleophiles under appropriate conditions, thus introducing other functional groups to lay the foundation for the construction of complex organic molecules; nitro groups can be converted into amino groups through reduction reactions to expand the reaction path of compounds, and then synthesize organic molecules with specific biological activities or functions. In the field of medicinal chemistry, it may be used to create new drug molecules.
In the field of materials science, 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene also has its uses. Due to its fluorine atoms and trifluoromethyl groups, it can endow materials with unique physical and chemical properties. Fluorine atoms have high electronegativity, which can enhance intermolecular forces, improve material stability and durability; the introduction of trifluoromethyl may improve the properties of materials such as chemical corrosion resistance, low surface energy and hydrophobicity. Therefore, it can be used to prepare high-performance coatings, special plastics or functional polymer materials, such as the preparation of coatings with good weather resistance, for outdoor facilities protection, which can make them resist harsh environmental erosion for a long time.
Furthermore, in the field of agricultural chemistry, it may also make a difference. Some organic compounds containing fluorine and nitro groups show certain biological activities, or can be used to develop new pesticides. 1-Chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene can be used as an intermediate, or through appropriate chemical modification, to create a pesticide product with efficient control effect on specific pests and diseases, and because of the presence of fluorine atoms, it may improve the environmental stability and biological activity of pesticides, reduce the dosage, and reduce the negative impact on the environment.
What are the physical properties of 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene
1-Chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene is one of the organic compounds. Its physical properties are particularly important and are related to many chemical applications.
First of all, on its appearance, under normal conditions, this substance is mostly colorless to light yellow liquid, the appearance is clear and transparent, like the quality of glaze, the view can be seen that its texture is uniform, without variegation and turbidity.
Secondary and boiling point, about a specific temperature range, usually under a certain external pressure, its boiling point can cause the substance to gradually change from liquid to gaseous state. The value of this boiling point is crucial in the setting of separation, purification and reaction conditions. The level of boiling point reflects the strength of intermolecular forces and is indispensable for the planning of chemical processes.
In addition, the melting point is also an important physical property. At the melting point, a substance changes from a solid state to a liquid state, and this transition temperature varies depending on the structure of the compound. The melting point of 1-chloro-2-fluoro-3-nitro-5 - (trifluoromethyl) benzene can help identify the purity of the substance. If the purity is high, the melting point range is narrow and approaches the theoretical value; if it contains impurities, the melting point is reduced and the range is widened.
Its density cannot be ignored. Compared with water, it is either lighter or heavier. This property is of great significance in liquid-liquid separation and phase equilibrium research. The density is affected by the molecular structure, atomic weight and intermolecular arrangement, and can be used to determine its distribution in the mixture.
In terms of solubility, it may have a certain solubility in organic solvents, such as common ethanol and ether, etc., while the solubility in water is relatively limited. This difference in solubility provides a basis for extraction, separation and other operations. It can be used to take advantage of the difference in solubility in different solvents to achieve effective separation of the compound from other substances.
In addition, vapor pressure is also one of its physical properties. Vapor pressure characterizes the difficulty of volatilization of a substance. In a closed container, the vapor pressure when it reaches equilibrium with the liquid phase reflects the tendency of molecules to escape from the liquid phase. The magnitude of the vapor pressure is related to the rate of its diffusion in the environment, and has an impact on safe production and environmental protection.
In summary, the physical properties of 1-chloro-2-fluoro-3-nitro-5 - (trifluoromethyl) benzene, such as appearance, boiling point, melting point, density, solubility, and vapor pressure, are of great value in chemical research, industrial production, and related fields, laying the foundation for in-depth exploration of its chemical behavior and applications.
First of all, on its appearance, under normal conditions, this substance is mostly colorless to light yellow liquid, the appearance is clear and transparent, like the quality of glaze, the view can be seen that its texture is uniform, without variegation and turbidity.
Secondary and boiling point, about a specific temperature range, usually under a certain external pressure, its boiling point can cause the substance to gradually change from liquid to gaseous state. The value of this boiling point is crucial in the setting of separation, purification and reaction conditions. The level of boiling point reflects the strength of intermolecular forces and is indispensable for the planning of chemical processes.
In addition, the melting point is also an important physical property. At the melting point, a substance changes from a solid state to a liquid state, and this transition temperature varies depending on the structure of the compound. The melting point of 1-chloro-2-fluoro-3-nitro-5 - (trifluoromethyl) benzene can help identify the purity of the substance. If the purity is high, the melting point range is narrow and approaches the theoretical value; if it contains impurities, the melting point is reduced and the range is widened.
Its density cannot be ignored. Compared with water, it is either lighter or heavier. This property is of great significance in liquid-liquid separation and phase equilibrium research. The density is affected by the molecular structure, atomic weight and intermolecular arrangement, and can be used to determine its distribution in the mixture.
In terms of solubility, it may have a certain solubility in organic solvents, such as common ethanol and ether, etc., while the solubility in water is relatively limited. This difference in solubility provides a basis for extraction, separation and other operations. It can be used to take advantage of the difference in solubility in different solvents to achieve effective separation of the compound from other substances.
In addition, vapor pressure is also one of its physical properties. Vapor pressure characterizes the difficulty of volatilization of a substance. In a closed container, the vapor pressure when it reaches equilibrium with the liquid phase reflects the tendency of molecules to escape from the liquid phase. The magnitude of the vapor pressure is related to the rate of its diffusion in the environment, and has an impact on safe production and environmental protection.
In summary, the physical properties of 1-chloro-2-fluoro-3-nitro-5 - (trifluoromethyl) benzene, such as appearance, boiling point, melting point, density, solubility, and vapor pressure, are of great value in chemical research, industrial production, and related fields, laying the foundation for in-depth exploration of its chemical behavior and applications.
Is 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene chemically stable?
The stability of the chemical properties of 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene is related to many chemical reasons. This compound has functional groups such as halogen atoms (chlorine and fluorine), nitro groups and trifluoromethyl groups.
In the halogen atom, the electronegativity of chlorine and fluorine is different, and the electronegativity of fluorine is particularly high, which makes the C-F bond energy larger, but also changes the electron cloud density of the benzene ring, which has an impact on the reactivity. Nitro is a strong electron-absorbing group, which can greatly reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution of the benzene ring, but it is conducive to the nucleophilic Because of its conjugation effect, the electron cloud density of the ortho and para-position of the benzene ring can be reduced even more. Under appropriate conditions, the ortho and para-position are vulnerable to attack by nucleophiles.
Trifluoromethyl is also a strong electron-absorbing group, which cooperates with the nitro group to exacerbate the reduction of the electron cloud density of the benzene ring, resulting in a unique performance of the overall chemical activity of the compound. Although the C-Cl bond is relatively active and can undergo reactions such as nucleophilic substitution, due to the existence of other strong electron-absorbing groups, the reaction conditions are different from those of general chloroaromatics.
In summary, the chemical properties of 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene are not extremely stable. Under suitable conditions, various chemical reactions can occur due to the interaction of the functional groups contained. The stability depends on the specific reaction conditions and the type of reaction involved.
In the halogen atom, the electronegativity of chlorine and fluorine is different, and the electronegativity of fluorine is particularly high, which makes the C-F bond energy larger, but also changes the electron cloud density of the benzene ring, which has an impact on the reactivity. Nitro is a strong electron-absorbing group, which can greatly reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution of the benzene ring, but it is conducive to the nucleophilic Because of its conjugation effect, the electron cloud density of the ortho and para-position of the benzene ring can be reduced even more. Under appropriate conditions, the ortho and para-position are vulnerable to attack by nucleophiles.
Trifluoromethyl is also a strong electron-absorbing group, which cooperates with the nitro group to exacerbate the reduction of the electron cloud density of the benzene ring, resulting in a unique performance of the overall chemical activity of the compound. Although the C-Cl bond is relatively active and can undergo reactions such as nucleophilic substitution, due to the existence of other strong electron-absorbing groups, the reaction conditions are different from those of general chloroaromatics.
In summary, the chemical properties of 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene are not extremely stable. Under suitable conditions, various chemical reactions can occur due to the interaction of the functional groups contained. The stability depends on the specific reaction conditions and the type of reaction involved.
What is the preparation method of 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene
The preparation method of 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene is particularly important. According to the ancient narrative of "Tiangong Kaiwu", it is described in detail below.
To make this substance, the common route is to start with benzene derivatives containing corresponding substituents. A benzene ring compound with a suitable substitution check point can be taken first, and chlorine atoms can be introduced under specific conditions. The introduction of chlorine atoms is often achieved by halogenation reaction. In the reaction system, select a suitable halogenating agent, such as a chlorine-containing halogenating agent, and control the reaction temperature, pressure and catalyst dosage. If the temperature is too high or too low, the reaction rate and the selectivity of the product can be changed.
Then fluorine atoms are introduced. The fluorination reaction requires special fluorine substitutes, because the reactivity and selectivity are different from common halogenation reactions. During the reaction, carefully adjust the reaction conditions so that the fluorine atoms fall precisely at the predetermined position of the benzene ring and prevent side reactions from occurring, so as to ensure the purity and yield of the target product. The introduction of nitro groups is mostly caused by nitrification reactions. A mixed acid system of nitric acid and sulfuric acid is commonly used. In this system, benzene ring derivatives interact with the mixed acid, and nitro groups replace the hydrogen atoms on the benzene ring. The key to this reaction is to control the ratio of mixed acids, reaction temperature and time. If the temperature is too high, it is easy to cause side reactions such as excessive nitrification or oxidation of the benzene ring; if the temperature is too low, the reaction rate will be slow and the production efficiency will be affected.
The introduction of trifluoromethyl can be achieved by specific reagents and reaction conditions. This step also needs to be carefully regulated to ensure that trifluoromethyl is successfully connected to the designated position of the benzene ring and does not damage the structure of other parts of the molecule.
After the reaction is completed, the product needs to be separated and purified. Common methods include distillation, extraction, recrystallization, etc. By distillation, it is separated according to the difference in the boiling point of each substance; extraction uses the different solubility of the solute in different solvents to extract; recrystallization is based on the difference in the solubility of the product and impurities Through this series of steps, a relatively pure 1-chloro-2-fluoro-3-nitro-5 - (trifluoromethyl) benzene can be obtained.
To make this substance, the common route is to start with benzene derivatives containing corresponding substituents. A benzene ring compound with a suitable substitution check point can be taken first, and chlorine atoms can be introduced under specific conditions. The introduction of chlorine atoms is often achieved by halogenation reaction. In the reaction system, select a suitable halogenating agent, such as a chlorine-containing halogenating agent, and control the reaction temperature, pressure and catalyst dosage. If the temperature is too high or too low, the reaction rate and the selectivity of the product can be changed.
Then fluorine atoms are introduced. The fluorination reaction requires special fluorine substitutes, because the reactivity and selectivity are different from common halogenation reactions. During the reaction, carefully adjust the reaction conditions so that the fluorine atoms fall precisely at the predetermined position of the benzene ring and prevent side reactions from occurring, so as to ensure the purity and yield of the target product. The introduction of nitro groups is mostly caused by nitrification reactions. A mixed acid system of nitric acid and sulfuric acid is commonly used. In this system, benzene ring derivatives interact with the mixed acid, and nitro groups replace the hydrogen atoms on the benzene ring. The key to this reaction is to control the ratio of mixed acids, reaction temperature and time. If the temperature is too high, it is easy to cause side reactions such as excessive nitrification or oxidation of the benzene ring; if the temperature is too low, the reaction rate will be slow and the production efficiency will be affected.
The introduction of trifluoromethyl can be achieved by specific reagents and reaction conditions. This step also needs to be carefully regulated to ensure that trifluoromethyl is successfully connected to the designated position of the benzene ring and does not damage the structure of other parts of the molecule.
After the reaction is completed, the product needs to be separated and purified. Common methods include distillation, extraction, recrystallization, etc. By distillation, it is separated according to the difference in the boiling point of each substance; extraction uses the different solubility of the solute in different solvents to extract; recrystallization is based on the difference in the solubility of the product and impurities Through this series of steps, a relatively pure 1-chloro-2-fluoro-3-nitro-5 - (trifluoromethyl) benzene can be obtained.
What are the precautions for 1-chloro-2-fluoro-3-nitro-5- (trifluoromethyl) benzene in storage and transportation?
1-Chloro-2-fluoro-3-nitro-5 - (trifluoromethyl) benzene is an organic compound. When storing and transporting, many matters must be paid attention to.
Storage first. This compound is unstable in nature and is prone to reaction in case of heat, light or specific substances. Therefore, it should be placed in a cool, dry and well-ventilated place away from fire and heat sources to avoid danger caused by heat energy. It is sensitive to light and should be stored in a dark container to prevent light-induced decomposition or deterioration of components. Furthermore, because of its certain toxicity and corrosiveness, it must be stored separately from oxidants, reducing agents, acids, alkalis, etc., to prevent the interaction of fire, explosion or release of toxic gases. The storage area should also be equipped with leakage emergency treatment equipment and suitable containment materials, so as to deal with accidental leakage in a timely manner.
As for transportation, it is necessary to ensure that the packaging is complete and sealed before transportation. The packaging material needs to be able to withstand the corrosion of the compound to avoid leakage during transportation. During transportation, the vehicle should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. Drivers and escorts must have professional knowledge and know the characteristics of the compound and emergency treatment methods. To follow the specified route, do not stop in densely populated areas and open flames. The transportation temperature also needs to be controlled to prevent the decomposition or volatilization of compounds caused by high temperature, which will cause safety problems. When loading and unloading, operators should wear protective equipment and handle lightly to avoid package damage caused by collision and friction.
Only by paying strict attention to the above matters during storage and transportation can we ensure the safety of 1-chloro-2-fluoro-3-nitro-5 - (trifluoromethyl) benzene and avoid accidents.
Storage first. This compound is unstable in nature and is prone to reaction in case of heat, light or specific substances. Therefore, it should be placed in a cool, dry and well-ventilated place away from fire and heat sources to avoid danger caused by heat energy. It is sensitive to light and should be stored in a dark container to prevent light-induced decomposition or deterioration of components. Furthermore, because of its certain toxicity and corrosiveness, it must be stored separately from oxidants, reducing agents, acids, alkalis, etc., to prevent the interaction of fire, explosion or release of toxic gases. The storage area should also be equipped with leakage emergency treatment equipment and suitable containment materials, so as to deal with accidental leakage in a timely manner.
As for transportation, it is necessary to ensure that the packaging is complete and sealed before transportation. The packaging material needs to be able to withstand the corrosion of the compound to avoid leakage during transportation. During transportation, the vehicle should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. Drivers and escorts must have professional knowledge and know the characteristics of the compound and emergency treatment methods. To follow the specified route, do not stop in densely populated areas and open flames. The transportation temperature also needs to be controlled to prevent the decomposition or volatilization of compounds caused by high temperature, which will cause safety problems. When loading and unloading, operators should wear protective equipment and handle lightly to avoid package damage caused by collision and friction.
Only by paying strict attention to the above matters during storage and transportation can we ensure the safety of 1-chloro-2-fluoro-3-nitro-5 - (trifluoromethyl) benzene and avoid accidents.
Scan to WhatsApp
