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1-Chloro-2-Iodo-4-Nitrobenzene
Linshang Chemical
|
HS Code |
751216 |
| Name | 1-Chloro-2-Iodo-4-Nitrobenzene |
| Molecular Formula | C6H3ClINO2 |
| Molecular Weight | 283.45 g/mol |
| Appearance | Solid |
| Melting Point | 97 - 101 °C |
| Solubility | Soluble in organic solvents like dichloromethane, chloroform |
| Purity | Typically high - purity for laboratory use |
| Cas Number | 634-93-5 |
| Chemical Class | Aryl halide and nitro - containing compound |
| Reactivity | Reactive towards nucleophilic substitution reactions |
As an accredited 1-Chloro-2-Iodo-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1 - chloro - 2 - iodo - 4 - nitrobenzene packaged in a sealed, labeled bottle. |
| Storage | 1 - Chloro - 2 - iodo - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents, reducing agents, and other reactive chemicals to avoid potential chemical reactions. Ensure proper labeling for easy identification. |
| Shipping | 1 - chloro - 2 - iodo - 4 - nitrobenzene, a chemical, should be shipped in sealed, corrosion - resistant containers. Label packages clearly with hazard warnings. Ensure compliance with regulations for transporting chemicals to prevent spills and risks. |
Competitive 1-Chloro-2-Iodo-4-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 1-Chloro-2-Iodo-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 1-chloro-2-iodo-4-nitrobenzene?
1-Chloro-2-iodine-4-nitrobenzene is also an organic compound. It has a number of chemical properties, which are described in detail as follows.
The substitution reaction is first described. Above the benzene ring, the nitro group is a strong electron-absorbing group, resulting in a decrease in the electron cloud density of the benzene ring and a weakening of the electrophilic substitution reaction activity. However, the electron cloud density of the adjacent and para-position of the halogen atom (chlorine and iodine) is relatively high, so the nucleophilic substitution reaction may occur. Under appropriate conditions, the nucleophilic reagent may attack the carbon site attached to the halogen atom, and the halogen atom leaves to form a new substitution product.
Re-discussion of its reduction reaction. Nitro can be reduced. If treated This process often requires specific reaction conditions, such as selecting a suitable catalyst, controlling temperature and pressure, etc. The reduction of nitro groups can greatly change the chemical properties and uses of the compound.
In addition, the halogen atoms in the compound have certain reactivity. Both chlorine and iodine atoms can participate in some organic synthesis reactions, such as coupling reactions. Under suitable catalytic systems, halogen atoms can be connected with other organic fragments to construct more complex organic molecular structures.
In addition, its chemical properties are also affected by intramolecular group interactions. There is an electronic interaction between nitro and halogen atoms, which affects the reactivity and stability of the molecule as a whole. This interaction allows the compound to exhibit unique reaction paths and products under different reaction conditions. The properties of the groups contained in 1-chloro-2-iodine-4-nitrophenylline make it an important intermediate for the preparation of various organic compounds.
The substitution reaction is first described. Above the benzene ring, the nitro group is a strong electron-absorbing group, resulting in a decrease in the electron cloud density of the benzene ring and a weakening of the electrophilic substitution reaction activity. However, the electron cloud density of the adjacent and para-position of the halogen atom (chlorine and iodine) is relatively high, so the nucleophilic substitution reaction may occur. Under appropriate conditions, the nucleophilic reagent may attack the carbon site attached to the halogen atom, and the halogen atom leaves to form a new substitution product.
Re-discussion of its reduction reaction. Nitro can be reduced. If treated This process often requires specific reaction conditions, such as selecting a suitable catalyst, controlling temperature and pressure, etc. The reduction of nitro groups can greatly change the chemical properties and uses of the compound.
In addition, the halogen atoms in the compound have certain reactivity. Both chlorine and iodine atoms can participate in some organic synthesis reactions, such as coupling reactions. Under suitable catalytic systems, halogen atoms can be connected with other organic fragments to construct more complex organic molecular structures.
In addition, its chemical properties are also affected by intramolecular group interactions. There is an electronic interaction between nitro and halogen atoms, which affects the reactivity and stability of the molecule as a whole. This interaction allows the compound to exhibit unique reaction paths and products under different reaction conditions. The properties of the groups contained in 1-chloro-2-iodine-4-nitrophenylline make it an important intermediate for the preparation of various organic compounds.
What are the physical properties of 1-chloro-2-iodo-4-nitrobenzene?
1-Chloro-2-iodo-4-nitrobenzene is an organic compound whose physical properties are crucial for a wide range of chemical applications.
This substance is usually in a solid state, which is due to the intermolecular forces at room temperature and pressure. As for the melting point, it is about a specific range. The melting point depends on the molecular structure and interaction. Substituents such as chlorine, iodine, and nitro have a significant impact on the intermolecular forces, which determine the melting point.
Its boiling point also has a corresponding value, reflecting the energy required to change from liquid to gas. The boiling point is related to the intermolecular forces and relative molecular weights. The relative molecular mass of the compound increases due to the presence of chlorine, iodine, nitro and other atoms or groups, and the intermolecular forces increase, resulting in an increase in boiling point.
In terms of solubility, the solubility in water is very small. Because its molecules are non-polar or weakly polar, while water is a polar solvent, according to the principle of "similar miscibility", the polarity difference is large, so it is difficult to dissolve in water. However, in some organic solvents, such as benzene, carbon tetrachloride and other non-polar or weakly polar organic solvents, the solubility will be improved, because it is similar to the intermolecular forces of these organic solvents and can be better miscible.
Appearance, or colorless to pale yellow solid, which is related to the absorption and reflection of visible light by its molecular structure. The specific structure causes the absorption and reflection of light to exhibit this color range.
The physical properties of 1-chloro-2-iodo-4-nitrobenzene are significantly affected by various groups in the molecular structure. These properties are of great significance in the fields of organic synthesis and drug development, helping researchers understand its behavior in different environments and laying the foundation for related applications.
This substance is usually in a solid state, which is due to the intermolecular forces at room temperature and pressure. As for the melting point, it is about a specific range. The melting point depends on the molecular structure and interaction. Substituents such as chlorine, iodine, and nitro have a significant impact on the intermolecular forces, which determine the melting point.
Its boiling point also has a corresponding value, reflecting the energy required to change from liquid to gas. The boiling point is related to the intermolecular forces and relative molecular weights. The relative molecular mass of the compound increases due to the presence of chlorine, iodine, nitro and other atoms or groups, and the intermolecular forces increase, resulting in an increase in boiling point.
In terms of solubility, the solubility in water is very small. Because its molecules are non-polar or weakly polar, while water is a polar solvent, according to the principle of "similar miscibility", the polarity difference is large, so it is difficult to dissolve in water. However, in some organic solvents, such as benzene, carbon tetrachloride and other non-polar or weakly polar organic solvents, the solubility will be improved, because it is similar to the intermolecular forces of these organic solvents and can be better miscible.
Appearance, or colorless to pale yellow solid, which is related to the absorption and reflection of visible light by its molecular structure. The specific structure causes the absorption and reflection of light to exhibit this color range.
The physical properties of 1-chloro-2-iodo-4-nitrobenzene are significantly affected by various groups in the molecular structure. These properties are of great significance in the fields of organic synthesis and drug development, helping researchers understand its behavior in different environments and laying the foundation for related applications.
What are the main uses of 1-chloro-2-iodo-4-nitrobenzene?
1-Chloro-2-iodine-4-nitrobenzene is also an organic compound. Its main use is quite wide, in the field of chemical synthesis, often used as an intermediate to produce various fine chemicals.
In the synthesis of medicine, or as a key raw material for the preparation of specific drug molecules. Due to the characteristics of halogen atoms and nitro groups in its structure, it can introduce other functional groups through chemical reactions to construct complex drug structures, which is expected to help the research and development of new medicines.
In the field of materials science, this compound may participate in the synthesis of special materials. The presence of halogen atoms and nitro groups can endow materials with unique physical and chemical properties, such as affecting the conductivity and optical properties of materials, so it may be used to develop new photoelectric materials.
In the study of organic synthetic chemistry, it is an important model compound. Chemists can use the investigation of its reactivity to gain insight into the interaction law of functional groups on the benzene ring, providing an important basis for the development of organic synthesis methodologies to develop more efficient and accurate synthesis paths. All of these are important uses of 1-chloro-2-iodine-4-nitrobenzene in chemical, pharmaceutical, materials and other fields.
In the synthesis of medicine, or as a key raw material for the preparation of specific drug molecules. Due to the characteristics of halogen atoms and nitro groups in its structure, it can introduce other functional groups through chemical reactions to construct complex drug structures, which is expected to help the research and development of new medicines.
In the field of materials science, this compound may participate in the synthesis of special materials. The presence of halogen atoms and nitro groups can endow materials with unique physical and chemical properties, such as affecting the conductivity and optical properties of materials, so it may be used to develop new photoelectric materials.
In the study of organic synthetic chemistry, it is an important model compound. Chemists can use the investigation of its reactivity to gain insight into the interaction law of functional groups on the benzene ring, providing an important basis for the development of organic synthesis methodologies to develop more efficient and accurate synthesis paths. All of these are important uses of 1-chloro-2-iodine-4-nitrobenzene in chemical, pharmaceutical, materials and other fields.
What are 1-chloro-2-iodo-4-nitrobenzene synthesis methods?
The synthesis methods of 1-chloro-2-iodine-4-nitrobenzene are quite various. The following is your detailed description.
First, benzene is used as the initial raw material. First, benzene is nitrified. Under the action of the mixed acid of concentrated sulfuric acid and concentrated nitric acid, nitrobenzene can be obtained. This reaction needs to be controlled at temperature to prevent the formation of polynitro substitution products. Then, nitrobenzene is halogenated, and chlorine atoms can be introduced into the benzene ring under the catalysis of a specific catalyst, such as ferric chloride or iron powder, and chlorine atoms can be introduced into the benzene ring to form chlorinated nitrobenzene. Finally, through the iodine substitution reaction, under suitable reaction conditions and the action of reagents, iodine For example, with iodine sources such as potassium iodide, with the assistance of certain oxidants, iodine substitution is completed to obtain 1-chloro-2-iodine-4-nitrobenzene.
Second, chlorobenzene can also be used as the starting material. First, chlorobenzene is nitrified. According to suitable nitrification conditions, the nitro group can be introduced into the para-position of chlorobenzene to obtain p-nitrochlorobenzene. Then, using a halogen atom exchange reaction, with a suitable iodide as the raw material, under the action of a specific solvent and catalyst, the chlorine atom is replaced by the iodine atom, so that the target product can also be synthesized.
Furthermore, if iodobenzene is used as the starting material, it Then, in a suitable reaction system, chlorine atoms are introduced at a specific position in the benzene ring. This process requires careful selection of reaction conditions and reagents to achieve the purpose of introducing chlorine atoms at the target position, and finally successfully synthesize 1-chloro-2-iodine-4-nitrobenzene.
All these synthesis methods have their own advantages and disadvantages. In practice, it is necessary to comprehensively consider the availability of raw materials, the difficulty of reaction conditions, the yield and cost, and carefully choose the most suitable synthesis path to obtain 1-chloro-2-iodine-4-nitrobenzene efficiently and economically.
First, benzene is used as the initial raw material. First, benzene is nitrified. Under the action of the mixed acid of concentrated sulfuric acid and concentrated nitric acid, nitrobenzene can be obtained. This reaction needs to be controlled at temperature to prevent the formation of polynitro substitution products. Then, nitrobenzene is halogenated, and chlorine atoms can be introduced into the benzene ring under the catalysis of a specific catalyst, such as ferric chloride or iron powder, and chlorine atoms can be introduced into the benzene ring to form chlorinated nitrobenzene. Finally, through the iodine substitution reaction, under suitable reaction conditions and the action of reagents, iodine For example, with iodine sources such as potassium iodide, with the assistance of certain oxidants, iodine substitution is completed to obtain 1-chloro-2-iodine-4-nitrobenzene.
Second, chlorobenzene can also be used as the starting material. First, chlorobenzene is nitrified. According to suitable nitrification conditions, the nitro group can be introduced into the para-position of chlorobenzene to obtain p-nitrochlorobenzene. Then, using a halogen atom exchange reaction, with a suitable iodide as the raw material, under the action of a specific solvent and catalyst, the chlorine atom is replaced by the iodine atom, so that the target product can also be synthesized.
Furthermore, if iodobenzene is used as the starting material, it Then, in a suitable reaction system, chlorine atoms are introduced at a specific position in the benzene ring. This process requires careful selection of reaction conditions and reagents to achieve the purpose of introducing chlorine atoms at the target position, and finally successfully synthesize 1-chloro-2-iodine-4-nitrobenzene.
All these synthesis methods have their own advantages and disadvantages. In practice, it is necessary to comprehensively consider the availability of raw materials, the difficulty of reaction conditions, the yield and cost, and carefully choose the most suitable synthesis path to obtain 1-chloro-2-iodine-4-nitrobenzene efficiently and economically.
1-chloro-2-iodo-4-nitrobenzene what are the precautions in storage and transportation?
1-Chloro-2-iodine-4-nitrobenzene is one of the organic compounds. When storing and transporting, pay attention to many matters.
First words storage. This compound has a certain chemical activity and should be stored in a cool, dry and well-ventilated place. If it is covered in a high temperature, humid environment, or causes chemical changes, it may even cause danger. The storage place must be kept away from fire and heat sources to avoid reaction due to rising temperature. And it should be stored separately from oxidizing agents, reducing agents, alkalis, etc., and should not be mixed. Contact with it or cause violent chemical reactions. At the same time, the storage container must be tightly sealed to prevent leakage, and corrosion-resistant materials, such as glass or specific plastics, should be used to prevent the container from being corroded and causing the compound to deteriorate.
Second talk about transportation. During transportation, it is necessary to ensure that the packaging is complete and firm. Packaging materials should be able to resist vibration, collision and friction, so as not to leak the compound. Transportation vehicles should also meet relevant safety standards and be equipped with fire extinguishing, leakage emergency treatment and other equipment. Transportation personnel must be professionally trained and familiar with the characteristics of this compound and emergency response methods. During transportation, they should not stop in dangerous areas such as densely populated areas and near fire sources. If there is a leak during transportation, effective measures should be taken immediately to evacuate the surrounding people, prevent the spread of pollution, and deal with the leak in the correct way.
In conclusion, the storage and transportation of 1-chloro-2-iodine-4-nitrobenzene is related to the safety and stability of the compound, and all aspects should be carefully carried out to ensure safety.
First words storage. This compound has a certain chemical activity and should be stored in a cool, dry and well-ventilated place. If it is covered in a high temperature, humid environment, or causes chemical changes, it may even cause danger. The storage place must be kept away from fire and heat sources to avoid reaction due to rising temperature. And it should be stored separately from oxidizing agents, reducing agents, alkalis, etc., and should not be mixed. Contact with it or cause violent chemical reactions. At the same time, the storage container must be tightly sealed to prevent leakage, and corrosion-resistant materials, such as glass or specific plastics, should be used to prevent the container from being corroded and causing the compound to deteriorate.
Second talk about transportation. During transportation, it is necessary to ensure that the packaging is complete and firm. Packaging materials should be able to resist vibration, collision and friction, so as not to leak the compound. Transportation vehicles should also meet relevant safety standards and be equipped with fire extinguishing, leakage emergency treatment and other equipment. Transportation personnel must be professionally trained and familiar with the characteristics of this compound and emergency response methods. During transportation, they should not stop in dangerous areas such as densely populated areas and near fire sources. If there is a leak during transportation, effective measures should be taken immediately to evacuate the surrounding people, prevent the spread of pollution, and deal with the leak in the correct way.
In conclusion, the storage and transportation of 1-chloro-2-iodine-4-nitrobenzene is related to the safety and stability of the compound, and all aspects should be carefully carried out to ensure safety.
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