Linshang Chemical
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1-Chloro-2-Isocyanatobenzene
Linshang Chemical
|
HS Code |
513563 |
| Chemical Formula | C7H4ClNO |
| Molar Mass | 153.565 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 236 - 238 °C |
| Density | 1.27 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents |
| Flash Point | 101 °C |
| Odor | Pungent |
As an accredited 1-Chloro-2-Isocyanatobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 2 - isocyanatobenzene packaged in 1 - kg bottles for secure storage and transport. |
| Storage | 1 - Chloro - 2 - isocyanatobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and incompatible substances such as strong acids, bases, and amines. Store it in a tightly sealed container to prevent leakage and exposure to moisture, which could initiate unwanted reactions. Use appropriate storage cabinets or areas designated for hazardous chemicals. |
| Shipping | 1 - Chloro - 2 - isocyanatobenzene is a hazardous chemical. Shipping requires proper packaging in accordance with regulations, like in UN - approved containers. It must be clearly labeled for its hazards, and transported by carriers licensed for such chemicals. |
Competitive 1-Chloro-2-Isocyanatobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 1-Chloro-2-Isocyanatobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-chloro-2-isocyanatobenzene?
1-Chloro-2-isocyanate benzene, this substance has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate.
The cover contains isocyanate and chlorine atoms, both of which have high reactivity and can participate in various organic reactions. It can meet with alcohols and react to form carbamate compounds. This carbamate is used in the field of polymer materials and is an important raw material for the synthesis of polyurethane. Polyurethane has many uses and is indispensable in foam plastics, coatings, adhesives and other industries.
Furthermore, when 1-chloro-2-isocyanate benzene meets amines, urea compounds will be produced. Ureas are of great significance in pesticides, medicine and other industries. In the field of pesticides, some urea compounds can be used as herbicides to help agricultural herbicides and ensure crop growth. In the field of medicine, some urea derivatives have unique biological activities and may become the basis for the development of new drugs.
And because of the presence of its benzene ring, it endows it with certain aromaticity and stability. This property makes it a key structural unit in the synthesis of organic compounds with special structures and properties. By modifying and transforming the substituents on its benzene ring, many organic compounds with novel structures and specific properties can be created to meet the needs of different fields. In short, 1-chloro-2-isocyanate benzene plays an important role in organic synthesis and related industries, and is an important substance for promoting the development of many fields.
The cover contains isocyanate and chlorine atoms, both of which have high reactivity and can participate in various organic reactions. It can meet with alcohols and react to form carbamate compounds. This carbamate is used in the field of polymer materials and is an important raw material for the synthesis of polyurethane. Polyurethane has many uses and is indispensable in foam plastics, coatings, adhesives and other industries.
Furthermore, when 1-chloro-2-isocyanate benzene meets amines, urea compounds will be produced. Ureas are of great significance in pesticides, medicine and other industries. In the field of pesticides, some urea compounds can be used as herbicides to help agricultural herbicides and ensure crop growth. In the field of medicine, some urea derivatives have unique biological activities and may become the basis for the development of new drugs.
And because of the presence of its benzene ring, it endows it with certain aromaticity and stability. This property makes it a key structural unit in the synthesis of organic compounds with special structures and properties. By modifying and transforming the substituents on its benzene ring, many organic compounds with novel structures and specific properties can be created to meet the needs of different fields. In short, 1-chloro-2-isocyanate benzene plays an important role in organic synthesis and related industries, and is an important substance for promoting the development of many fields.
What are the physical properties of 1-chloro-2-isocyanatobenzene?
1-Chloro-2-isocyanate phenyl ester is one of the organic compounds. It has unique physical properties, which I will describe in detail for you.
First of all, its appearance, 1-chloro-2-isocyanate phenyl ester is mostly colorless to light yellow liquid at room temperature. Looking at it, it has a certain fluidity and is like a clear oil, but its properties are different and cannot be ignored.
As for the boiling point, it is between 215 ° C and 217 ° C. The value of this boiling point determines its physical state change under a specific temperature environment. When the external temperature rises to this boiling point, the substance gradually converts from liquid to gas and escapes in the air.
In terms of melting point, it is about -1 ° C. This means that when the temperature drops to about -1 ° C, the substance will condense from liquid to solid, and its molecules will be arranged in a regular and orderly manner.
Furthermore, when it comes to density, it is about 1.27 g/cm ³. This density value indicates that it is heavier than water, and if mixed with water, it will sink to the bottom of the water.
The vapor pressure of 1-chloro-2-isocyanate phenyl ester is also an important physical property. At a certain temperature, the pressure of the steam when it is in a closed container and the gas-liquid equilibrium depends on the degree of its volatilization. The higher the vapor pressure, the more volatile the substance is at the corresponding temperature, and the trend of diffusion in the air is stronger.
In addition, its solubility also needs to be paid attention to. In organic solvents, such as benzene and toluene of aromatic hydrocarbons, dichloromethane of halogenated hydrocarbons, etc., 1-chloro-2-isocyanate phenyl ester has good solubility and can be mutually soluble with it to form a uniform mixed system. However, in water, its solubility is extremely poor. Due to the characteristics of its molecular structure, it is difficult to form an effective interaction with water molecules, so it is mostly suspended or sank in droplets.
The above physical properties are all key factors to consider in the fields of chemical production, scientific research and experiments, and are relevant to the storage, transportation and use of this substance.
First of all, its appearance, 1-chloro-2-isocyanate phenyl ester is mostly colorless to light yellow liquid at room temperature. Looking at it, it has a certain fluidity and is like a clear oil, but its properties are different and cannot be ignored.
As for the boiling point, it is between 215 ° C and 217 ° C. The value of this boiling point determines its physical state change under a specific temperature environment. When the external temperature rises to this boiling point, the substance gradually converts from liquid to gas and escapes in the air.
In terms of melting point, it is about -1 ° C. This means that when the temperature drops to about -1 ° C, the substance will condense from liquid to solid, and its molecules will be arranged in a regular and orderly manner.
Furthermore, when it comes to density, it is about 1.27 g/cm ³. This density value indicates that it is heavier than water, and if mixed with water, it will sink to the bottom of the water.
The vapor pressure of 1-chloro-2-isocyanate phenyl ester is also an important physical property. At a certain temperature, the pressure of the steam when it is in a closed container and the gas-liquid equilibrium depends on the degree of its volatilization. The higher the vapor pressure, the more volatile the substance is at the corresponding temperature, and the trend of diffusion in the air is stronger.
In addition, its solubility also needs to be paid attention to. In organic solvents, such as benzene and toluene of aromatic hydrocarbons, dichloromethane of halogenated hydrocarbons, etc., 1-chloro-2-isocyanate phenyl ester has good solubility and can be mutually soluble with it to form a uniform mixed system. However, in water, its solubility is extremely poor. Due to the characteristics of its molecular structure, it is difficult to form an effective interaction with water molecules, so it is mostly suspended or sank in droplets.
The above physical properties are all key factors to consider in the fields of chemical production, scientific research and experiments, and are relevant to the storage, transportation and use of this substance.
What is the chemistry of 1-chloro-2-isocyanatobenzene?
1-Chloro-2-isocyanate benzene, an organic compound with unique and complex chemical properties, let me explain in detail.
In terms of its activity, isocyanate (-NCO) is extremely active. The nitrogen atom in isocyanate is connected to the carbon atom by a double bond, and the nitrogen atom is partially positively charged, and the carbon atom is partially negatively charged. This electron cloud distribution makes it prone to react with compounds containing active hydrogen. For example, when it encounters water, the hydrogen atom of the water quickly binds to the nitrogen atom in the isocyanate, while the hydroxyl group binds to the carbon atom to form the corresponding amine group and carbon dioxide. This reaction is quite rapid and violent. When
comes into contact with alcohols, the hydrogen atom on the hydroxyl group of the alcohol will combine with the nitrogen atom in the isocyanate, and the alkoxy group will connect with the carbon atom to form carbamate compounds. This reaction is often used in the preparation of polyurethane materials in industry and is widely used.
Furthermore, the benzene ring also has a significant impact on the properties of the compound. The benzene ring has a conjugated system, which makes it stable. However, the chlorine atom attached to the benzene ring, because of its strong electronegativity, will reduce the electron cloud density of the benzene ring, which in turn affects the electrophilic substitution reaction activity on the benzene ring. Compared with ordinary benzene, when 1-chloro-2-isocyanate benzene undergoes electrophilic substitution reaction, the reaction conditions may be more severe, and the substitution position is affected by the positioning effect of chlorine atoms and isocyanate.
At the same time, due to the interaction between isocyanate and benzene ring conjugation system, the activity of isocyanate is changed to a certain extent. Compared with simple alkyl isocyanate, its reactivity and selectivity are different. In the field of organic synthesis, this property can be cleverly exploited to construct organic compounds with diverse structures. In conclusion, the chemical properties of 1-chloro-2-isocyanate benzene are rich and diverse, and it has important value and application prospects in many fields such as organic synthesis and materials science.
In terms of its activity, isocyanate (-NCO) is extremely active. The nitrogen atom in isocyanate is connected to the carbon atom by a double bond, and the nitrogen atom is partially positively charged, and the carbon atom is partially negatively charged. This electron cloud distribution makes it prone to react with compounds containing active hydrogen. For example, when it encounters water, the hydrogen atom of the water quickly binds to the nitrogen atom in the isocyanate, while the hydroxyl group binds to the carbon atom to form the corresponding amine group and carbon dioxide. This reaction is quite rapid and violent. When
comes into contact with alcohols, the hydrogen atom on the hydroxyl group of the alcohol will combine with the nitrogen atom in the isocyanate, and the alkoxy group will connect with the carbon atom to form carbamate compounds. This reaction is often used in the preparation of polyurethane materials in industry and is widely used.
Furthermore, the benzene ring also has a significant impact on the properties of the compound. The benzene ring has a conjugated system, which makes it stable. However, the chlorine atom attached to the benzene ring, because of its strong electronegativity, will reduce the electron cloud density of the benzene ring, which in turn affects the electrophilic substitution reaction activity on the benzene ring. Compared with ordinary benzene, when 1-chloro-2-isocyanate benzene undergoes electrophilic substitution reaction, the reaction conditions may be more severe, and the substitution position is affected by the positioning effect of chlorine atoms and isocyanate.
At the same time, due to the interaction between isocyanate and benzene ring conjugation system, the activity of isocyanate is changed to a certain extent. Compared with simple alkyl isocyanate, its reactivity and selectivity are different. In the field of organic synthesis, this property can be cleverly exploited to construct organic compounds with diverse structures. In conclusion, the chemical properties of 1-chloro-2-isocyanate benzene are rich and diverse, and it has important value and application prospects in many fields such as organic synthesis and materials science.
What are 1-chloro-2-isocyanatobenzene synthesis methods?
The synthesis method of 1-chloro-2-isocyanate benzene has attracted much attention in the field of organic synthesis. Many scholars in the past have been studying this, and the following are several common methods.
One is to use o-chloroaniline as the starting material. Shilling o-chloroaniline interacts with phosgene under suitable reaction conditions. Phosgene is an important chemical raw material. In this reaction, it undergoes a specific chemical reaction with o-chloroaniline. During the reaction, the temperature, pressure and the ratio of reactants need to be precisely controlled. If the temperature is too high or too low, the reaction product may be impure or the reaction rate may be poor. The regulation of pressure is also crucial. The appropriate pressure environment can promote the smooth progress of the reaction towards the formation of 1-chloro-2-isocyanate benzene. After this reaction, the molecular structure of o-chloroaniline is changed and gradually converted into the target product.
Second, o-chlorobenzoic acid can also be used as a starting material. First, the o-chlorobenzoic acid is converted into its acid chloride form. This step requires the help of specific chlorination reagents, such as dichlorosulfoxide. The chlorination reagent reacts with the o-chlorobenzoic acid to convert the carboxyl group into an acyl chloride group. Subsequently, the acid chloride product reacts with cyanide-containing reagents such as sodium cyanate. This reaction process also requires strict control of the reaction conditions, such as the choice of reaction solvent. Different solvents have a significant impact on the reaction rate and product selectivity. The reaction time cannot be ignored. If the time is too short, the reaction may be incomplete; if the time is too long, it may lead to side reactions and reduce the yield of the target product.
Furthermore, o-chlorobenzamide can also be considered as the starting material. Through specific dehydrating agents, such as phosphorus pentoxide, o-chlorobenzamide dehydrates, resulting in the formation of 1-chloro-2-isocyanate benzene. In this process, the amount of dehydrating agent, reaction temperature and time are all key factors. If the dosage is too small, the dehydration reaction cannot be carried out completely; if the dosage is too large, other unnecessary side reactions may be triggered. Improper control of temperature and time will also have adverse effects on the quality and yield of the product.
The above several methods for synthesizing 1-chloro-2-isocyanate benzene have their own advantages and disadvantages. In practical applications, it is necessary to choose carefully according to specific needs and conditions.
One is to use o-chloroaniline as the starting material. Shilling o-chloroaniline interacts with phosgene under suitable reaction conditions. Phosgene is an important chemical raw material. In this reaction, it undergoes a specific chemical reaction with o-chloroaniline. During the reaction, the temperature, pressure and the ratio of reactants need to be precisely controlled. If the temperature is too high or too low, the reaction product may be impure or the reaction rate may be poor. The regulation of pressure is also crucial. The appropriate pressure environment can promote the smooth progress of the reaction towards the formation of 1-chloro-2-isocyanate benzene. After this reaction, the molecular structure of o-chloroaniline is changed and gradually converted into the target product.
Second, o-chlorobenzoic acid can also be used as a starting material. First, the o-chlorobenzoic acid is converted into its acid chloride form. This step requires the help of specific chlorination reagents, such as dichlorosulfoxide. The chlorination reagent reacts with the o-chlorobenzoic acid to convert the carboxyl group into an acyl chloride group. Subsequently, the acid chloride product reacts with cyanide-containing reagents such as sodium cyanate. This reaction process also requires strict control of the reaction conditions, such as the choice of reaction solvent. Different solvents have a significant impact on the reaction rate and product selectivity. The reaction time cannot be ignored. If the time is too short, the reaction may be incomplete; if the time is too long, it may lead to side reactions and reduce the yield of the target product.
Furthermore, o-chlorobenzamide can also be considered as the starting material. Through specific dehydrating agents, such as phosphorus pentoxide, o-chlorobenzamide dehydrates, resulting in the formation of 1-chloro-2-isocyanate benzene. In this process, the amount of dehydrating agent, reaction temperature and time are all key factors. If the dosage is too small, the dehydration reaction cannot be carried out completely; if the dosage is too large, other unnecessary side reactions may be triggered. Improper control of temperature and time will also have adverse effects on the quality and yield of the product.
The above several methods for synthesizing 1-chloro-2-isocyanate benzene have their own advantages and disadvantages. In practical applications, it is necessary to choose carefully according to specific needs and conditions.
1-chloro-2-isocyanatobenzene what are the precautions during use
When using 1-chloro-2-isocyanate benzene, many things should be paid attention to. This is a toxic and irritating substance that can cause harm if it touches the skin, eyes or inhales its vapor. Therefore, when using, protective gear must be comprehensive, such as protective clothing, protective gloves and goggles, and handled in a well-ventilated place to avoid vapor accumulation and damage to the body.
In addition, 1-chloro-2-isocyanate benzene has high chemical activity and is easy to react with water, alcohols, amines and other substances. When using it, avoid contact with various active substances to prevent uncontrolled reactions, such as explosions, fires, etc. After use, proper storage is also key. It should be placed in a cool, dry and ventilated place, away from fire sources, heat sources and incompatible objects, to prevent deterioration or accidents.
During operation, accurate measurement and careful operation are indispensable. Due to its strong reactivity, wrong dosage or sparse operation can cause reaction deviations, affect the quality and quantity of the product, and even cause safety risks. At the same time, the relevant reaction equipment needs to be clean, dry and adapted to ensure the smooth and safe progress of the reaction.
In addition, in the event of an accidental spill during use, act promptly according to the established emergency response procedures. Small spills can be absorbed by inert materials such as sand and vermiculite; large spills need to be constructed or excavated for containment, and transferred to a special collector with an explosion-proof pump for proper disposal.
In addition, 1-chloro-2-isocyanate benzene has high chemical activity and is easy to react with water, alcohols, amines and other substances. When using it, avoid contact with various active substances to prevent uncontrolled reactions, such as explosions, fires, etc. After use, proper storage is also key. It should be placed in a cool, dry and ventilated place, away from fire sources, heat sources and incompatible objects, to prevent deterioration or accidents.
During operation, accurate measurement and careful operation are indispensable. Due to its strong reactivity, wrong dosage or sparse operation can cause reaction deviations, affect the quality and quantity of the product, and even cause safety risks. At the same time, the relevant reaction equipment needs to be clean, dry and adapted to ensure the smooth and safe progress of the reaction.
In addition, in the event of an accidental spill during use, act promptly according to the established emergency response procedures. Small spills can be absorbed by inert materials such as sand and vermiculite; large spills need to be constructed or excavated for containment, and transferred to a special collector with an explosion-proof pump for proper disposal.
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