Linshang Chemical
PRODUCTS
1-Chloro-3-Fluoro-2-Methoxybenzene
Linshang Chemical
|
HS Code |
390264 |
| Chemical Formula | C7H6ClFO |
| Molecular Weight | 160.573 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 187 - 189 °C |
| Melting Point | N/A |
| Density | 1.258 g/cm³ |
| Flash Point | 70 °C |
| Solubility In Water | Insoluble |
| Vapor Pressure | N/A |
| Refractive Index | 1.498 - 1.502 |
As an accredited 1-Chloro-3-Fluoro-2-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 3 - fluoro - 2 - methoxybenzene in 500g bottles, well - sealed for chemical storage. |
| Storage | 1 - Chloro - 3 - fluoro - 2 - methoxybenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames as it is likely flammable. Keep it in a tightly sealed container to prevent evaporation and exposure to air and moisture. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions. |
| Shipping | 1 - Chloro - 3 - fluoro - 2 - methoxybenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring proper labeling and safe transportation to prevent any leakage or risks. |
Competitive 1-Chloro-3-Fluoro-2-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Chloro-3-Fluoro-2-Methoxybenzene in China?
As a trusted 1-Chloro-3-Fluoro-2-Methoxybenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Chloro-3-Fluoro-2-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-chloro-3-fluoro-2-methoxybenzene?
1-Chloro-3-fluoro-2-methoxybenzene is also an organic compound. It has a wide range of uses and is widely used in various fields of chemical industry.
In the process of pharmaceutical synthesis, this compound is often a key intermediate. Due to its unique chemical structure, it can introduce specific functional groups through many chemical reactions to build the skeleton of various drug molecules. With clever reaction design, it can be converted into compounds with specific pharmacological activities, which can be used to create new drugs and treat various diseases, such as anti-infection and anti-tumor.
In the field of materials science, 1-chloro-3-fluoro-2-methoxybenzene also has its uses. It can be used as a raw material to prepare polymer materials with specific properties through polymerization or other chemical modification methods. Such materials may have excellent thermal stability, mechanical properties, or unique optical and electrical properties, and have potential application value in many cutting-edge fields such as electronic devices and aerospace.
In addition, it is also common in the preparation of fine chemical products. For example, it is used to synthesize special fragrances, dyes, etc. Because its structure can give the product unique color, smell or other special properties, it can meet the market demand for high-quality, differentiated fine chemical products. Therefore, 1-chloro-3-fluoro-2-methoxybenzene is of indispensable significance in the development of the chemical industry.
In the process of pharmaceutical synthesis, this compound is often a key intermediate. Due to its unique chemical structure, it can introduce specific functional groups through many chemical reactions to build the skeleton of various drug molecules. With clever reaction design, it can be converted into compounds with specific pharmacological activities, which can be used to create new drugs and treat various diseases, such as anti-infection and anti-tumor.
In the field of materials science, 1-chloro-3-fluoro-2-methoxybenzene also has its uses. It can be used as a raw material to prepare polymer materials with specific properties through polymerization or other chemical modification methods. Such materials may have excellent thermal stability, mechanical properties, or unique optical and electrical properties, and have potential application value in many cutting-edge fields such as electronic devices and aerospace.
In addition, it is also common in the preparation of fine chemical products. For example, it is used to synthesize special fragrances, dyes, etc. Because its structure can give the product unique color, smell or other special properties, it can meet the market demand for high-quality, differentiated fine chemical products. Therefore, 1-chloro-3-fluoro-2-methoxybenzene is of indispensable significance in the development of the chemical industry.
What are the physical properties of 1-chloro-3-fluoro-2-methoxybenzene?
1-Chloro-3-fluoro-2-methoxybenzene is a genus of organic compounds. Its physical properties are quite impressive.
Looking at its appearance, under normal circumstances, it is usually a colorless to light yellow transparent liquid, just like a clear liquid, with a shimmer in the flow. This substance has a specific smell, but it is not pungent and intolerable, but it also has a unique smell of a chemical substance, which is light and discernible.
When it comes to the melting point, the melting point is very low, and it can usually condense into a solid state in extremely cold conditions, just like water that is not easy to solidify in cold nights. The boiling point is moderate, and within a specific temperature range, it can be converted from liquid to gaseous state, evaporating like a cloud rising. This characteristic is crucial in chemical operations, related to the process of separation and purification.
Furthermore, its density is different from that of water, slightly larger than that of water. If it is poured into water, it will slowly sink and form its own body under the water layer. In terms of solubility, this compound is soluble in organic solvents such as ethanol and ether, as if it is integrated into it, and it is integrated with it, while it is insoluble in water, just like the mutual exclusion of oil and water, with clear boundaries.
In addition, the volatility of 1-chloro-3-fluoro-2-methoxybenzene also has characteristics. Although it is not very volatile, under appropriate conditions, such as heating or in a ventilated environment, the molecules are active and gradually escape into the air, like light smoke. This volatility needs to be carefully considered during storage and use to prevent its loss and cause safety risks. All these physical properties are indispensable factors in chemical synthesis, application and other fields, which affect the selection of its process and the operation procedures.
Looking at its appearance, under normal circumstances, it is usually a colorless to light yellow transparent liquid, just like a clear liquid, with a shimmer in the flow. This substance has a specific smell, but it is not pungent and intolerable, but it also has a unique smell of a chemical substance, which is light and discernible.
When it comes to the melting point, the melting point is very low, and it can usually condense into a solid state in extremely cold conditions, just like water that is not easy to solidify in cold nights. The boiling point is moderate, and within a specific temperature range, it can be converted from liquid to gaseous state, evaporating like a cloud rising. This characteristic is crucial in chemical operations, related to the process of separation and purification.
Furthermore, its density is different from that of water, slightly larger than that of water. If it is poured into water, it will slowly sink and form its own body under the water layer. In terms of solubility, this compound is soluble in organic solvents such as ethanol and ether, as if it is integrated into it, and it is integrated with it, while it is insoluble in water, just like the mutual exclusion of oil and water, with clear boundaries.
In addition, the volatility of 1-chloro-3-fluoro-2-methoxybenzene also has characteristics. Although it is not very volatile, under appropriate conditions, such as heating or in a ventilated environment, the molecules are active and gradually escape into the air, like light smoke. This volatility needs to be carefully considered during storage and use to prevent its loss and cause safety risks. All these physical properties are indispensable factors in chemical synthesis, application and other fields, which affect the selection of its process and the operation procedures.
What are 1-chloro-3-fluoro-2-methoxybenzene synthesis methods?
There are several methods for synthesizing 1-chloro-3-fluoro-2-methoxybenzene.
First, o-methoxyphenol is used as the starting material. First, the o-methoxyphenol is reacted with a halogenating reagent. If it reacts with a chlorination reagent under suitable conditions, a chlorine atom can be introduced at a specific position in the benzene ring to obtain a chlorine-containing derivative. Then, a suitable fluorination reagent is selected, and a fluorine atom is introduced into another position of the benzene ring in a suitable reaction environment. After a series of reaction operations, 1-chloro-3-fluoro-2-methoxybenzene is finally successfully obtained. The key to this route lies in the precise control of the reaction conditions of each step. The sequence of halogenation and fluorination steps and the proportion of reagent dosage all have a great influence on the purity and yield of the product.
Second, the halogenated benzene derivative is used as the starting material. Select a suitable halogenated benzene, whose benzene ring already contains some of the desired substituents, and methoxy is introduced through methoxylation. This reaction requires a suitable base and catalyst. Under a certain temperature and reaction time, the halogenated benzene and the methoxylating reagent undergo nucleophilic substitution. Subsequently, chlorine and fluorine atoms are introduced at designated positions through selective halogenation reaction, and the target product 1-chloro-3-fluoro-2-methoxybenzene is obtained through subsequent operations such as separation and purification. This path focuses on the efficiency and selectivity of methoxylation reaction, and the effect of subsequent halogenation reaction on existing substituents.
Third, anisole derivatives are used as starting materials. First, anisole is halogenated, and chlorine and fluorine atoms are selectively introduced into the benzene ring to construct the halogenated anisole intermediate. This needs to be regulated according to the characteristics of the halogenated reagents and reaction conditions to achieve the expected substitution position and degree of substitution. After that, appropriate functional group transformation and modification are carried out to finally synthesize 1-chloro-3-fluoro-2-methoxybenzene. This approach requires attention to the regioselectivity of the halogenation reaction and the feasibility and yield of subsequent functional group conversion steps.
Each synthesis method has its own advantages and disadvantages. In practical applications, it is necessary to comprehensively consider many factors such as raw material cost, difficulty of reaction conditions, product purity and yield, and carefully select the appropriate synthesis path.
First, o-methoxyphenol is used as the starting material. First, the o-methoxyphenol is reacted with a halogenating reagent. If it reacts with a chlorination reagent under suitable conditions, a chlorine atom can be introduced at a specific position in the benzene ring to obtain a chlorine-containing derivative. Then, a suitable fluorination reagent is selected, and a fluorine atom is introduced into another position of the benzene ring in a suitable reaction environment. After a series of reaction operations, 1-chloro-3-fluoro-2-methoxybenzene is finally successfully obtained. The key to this route lies in the precise control of the reaction conditions of each step. The sequence of halogenation and fluorination steps and the proportion of reagent dosage all have a great influence on the purity and yield of the product.
Second, the halogenated benzene derivative is used as the starting material. Select a suitable halogenated benzene, whose benzene ring already contains some of the desired substituents, and methoxy is introduced through methoxylation. This reaction requires a suitable base and catalyst. Under a certain temperature and reaction time, the halogenated benzene and the methoxylating reagent undergo nucleophilic substitution. Subsequently, chlorine and fluorine atoms are introduced at designated positions through selective halogenation reaction, and the target product 1-chloro-3-fluoro-2-methoxybenzene is obtained through subsequent operations such as separation and purification. This path focuses on the efficiency and selectivity of methoxylation reaction, and the effect of subsequent halogenation reaction on existing substituents.
Third, anisole derivatives are used as starting materials. First, anisole is halogenated, and chlorine and fluorine atoms are selectively introduced into the benzene ring to construct the halogenated anisole intermediate. This needs to be regulated according to the characteristics of the halogenated reagents and reaction conditions to achieve the expected substitution position and degree of substitution. After that, appropriate functional group transformation and modification are carried out to finally synthesize 1-chloro-3-fluoro-2-methoxybenzene. This approach requires attention to the regioselectivity of the halogenation reaction and the feasibility and yield of subsequent functional group conversion steps.
Each synthesis method has its own advantages and disadvantages. In practical applications, it is necessary to comprehensively consider many factors such as raw material cost, difficulty of reaction conditions, product purity and yield, and carefully select the appropriate synthesis path.
1-chloro-3-fluoro-2-methoxybenzene need to pay attention to when storing and transporting
1-Chloro-3-fluoro-2-methoxybenzene is also an organic compound. When storing and transporting, many things should be paid attention to.
Safety should be taken into account first. This compound may be toxic and irritating, so the storage place must be dry, well ventilated, and away from fire and heat sources to prevent fire and explosion. When transporting, it is also necessary to ensure that the packaging is stable and does not leak.
This is to avoid contact. When handling this object, prepare protective equipment, such as gloves, goggles, gas masks, etc., to prevent it from coming into contact with the skin, eyes and respiratory tract and causing physical damage.
Furthermore, pay attention to storage conditions. It should be stored in a cool place, and the temperature should not be too high to prevent its deterioration or chemical reaction. And it needs to be stored separately from oxidizing agents, acids, alkalis and other substances. Because of its active chemical properties, it will come into contact with them or react violently.
When transporting, appropriate transportation methods and tools should be selected in accordance with relevant laws and regulations. Be sure to ensure that transporters are familiar with the characteristics and emergency treatment methods of this substance. In case of emergencies such as leakage, they can be disposed of quickly and properly.
In addition, the label marking should not be ignored. On storage containers and transportation packages, information such as compound names, characteristics, and hazard warnings should be clearly marked so that relevant personnel can identify and protect.
In conclusion, the storage and transportation of 1-chloro-3-fluoro-2-methoxybenzene requires careful treatment and strict adherence to safety regulations to ensure the safety of personnel and the environment.
Safety should be taken into account first. This compound may be toxic and irritating, so the storage place must be dry, well ventilated, and away from fire and heat sources to prevent fire and explosion. When transporting, it is also necessary to ensure that the packaging is stable and does not leak.
This is to avoid contact. When handling this object, prepare protective equipment, such as gloves, goggles, gas masks, etc., to prevent it from coming into contact with the skin, eyes and respiratory tract and causing physical damage.
Furthermore, pay attention to storage conditions. It should be stored in a cool place, and the temperature should not be too high to prevent its deterioration or chemical reaction. And it needs to be stored separately from oxidizing agents, acids, alkalis and other substances. Because of its active chemical properties, it will come into contact with them or react violently.
When transporting, appropriate transportation methods and tools should be selected in accordance with relevant laws and regulations. Be sure to ensure that transporters are familiar with the characteristics and emergency treatment methods of this substance. In case of emergencies such as leakage, they can be disposed of quickly and properly.
In addition, the label marking should not be ignored. On storage containers and transportation packages, information such as compound names, characteristics, and hazard warnings should be clearly marked so that relevant personnel can identify and protect.
In conclusion, the storage and transportation of 1-chloro-3-fluoro-2-methoxybenzene requires careful treatment and strict adherence to safety regulations to ensure the safety of personnel and the environment.
1-chloro-3-fluoro-2-methoxybenzene security risks
1 - chloro - 3 - fluoro - 2 - methoxybenzene is one of the organic compounds. In terms of its safety risks, it needs to be investigated from various angles.
First of all, its physical properties, this compound is a liquid, with a specific boiling point, melting point and density. At room temperature, its volatility or affect the surrounding environment. If it is in a closed space, the volatile gas will accumulate, or increase the risk of fire and explosion.
Then look at its chemical activity. The presence of chlorine, fluorine and methoxy groups gives it unique chemical properties. In case of strong oxidants, it may react violently, or even cause an explosion. The presence of methoxy groups may make compounds more susceptible to substitution or addition reactions with certain substances. During this reaction, a large amount of heat may be released, endangering safety.
Toxicological properties cannot be ignored. Although there are no detailed toxicological data, halogenated aromatic hydrocarbons are often toxic. Or absorbed through the respiratory tract and skin, harming human health. Such as irritating respiratory mucosa, causing cough, asthma; long-term exposure, or damaging liver, kidney and other organ functions.
In the environment, it is discharged into the environment, or transported and transformed through the atmosphere, water, and soil. In water bodies, or affect the survival and reproduction of aquatic organisms; in soil, or inhibit plant growth, destroying ecological balance.
Therefore, 1-chloro-3-fluoro-2-methoxybenzene is a safety risk. In production, storage, transportation and use, it is necessary to strictly abide by safety procedures and take protective measures, such as strengthening ventilation and wearing protective equipment, to reduce risks and ensure the safety of personnel and the environment.
First of all, its physical properties, this compound is a liquid, with a specific boiling point, melting point and density. At room temperature, its volatility or affect the surrounding environment. If it is in a closed space, the volatile gas will accumulate, or increase the risk of fire and explosion.
Then look at its chemical activity. The presence of chlorine, fluorine and methoxy groups gives it unique chemical properties. In case of strong oxidants, it may react violently, or even cause an explosion. The presence of methoxy groups may make compounds more susceptible to substitution or addition reactions with certain substances. During this reaction, a large amount of heat may be released, endangering safety.
Toxicological properties cannot be ignored. Although there are no detailed toxicological data, halogenated aromatic hydrocarbons are often toxic. Or absorbed through the respiratory tract and skin, harming human health. Such as irritating respiratory mucosa, causing cough, asthma; long-term exposure, or damaging liver, kidney and other organ functions.
In the environment, it is discharged into the environment, or transported and transformed through the atmosphere, water, and soil. In water bodies, or affect the survival and reproduction of aquatic organisms; in soil, or inhibit plant growth, destroying ecological balance.
Therefore, 1-chloro-3-fluoro-2-methoxybenzene is a safety risk. In production, storage, transportation and use, it is necessary to strictly abide by safety procedures and take protective measures, such as strengthening ventilation and wearing protective equipment, to reduce risks and ensure the safety of personnel and the environment.
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