Linshang Chemical
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1-Chloro-3-Iodo-2-Methylbenzene
Linshang Chemical
|
HS Code |
211259 |
| Chemical Formula | C7H6ClI |
| Molar Mass | 254.48 g/mol |
| Appearance | liquid (presumably, common for such aromatic halides) |
| Solubility In Water | insoluble (aromatic halides are generally hydrophobic) |
| Solubility In Organic Solvents | soluble in common organic solvents like ethanol, ether |
As an accredited 1-Chloro-3-Iodo-2-Methylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1 - chloro - 3 - iodo - 2 - methylbenzene packaged in a sealed glass bottle. |
| Storage | 1 - Chloro - 3 - iodo - 2 - methylbenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of a material resistant to chemical corrosion, like glass. Avoid storing it near oxidizing agents or reactive substances to prevent potential chemical reactions. |
| Shipping | 1 - Chloro - 3 - iodo - 2 - methylbenzene is shipped in well - sealed, corrosion - resistant containers. It's handled as a hazardous chemical, following strict regulations to ensure safe transport, minimizing risks during transit. |
Competitive 1-Chloro-3-Iodo-2-Methylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
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What is the Chinese name of 1-chloro-3-iodo-2-methylbenzene?
1-Chloro-3-iodine-2-methylbenzene is a name given to organic compounds. According to the chemical nomenclature, it is attached to the benzene ring with a chlorine atom at the first position, an iodine atom at the third position, and a methyl group at the second position. The
benzene ring is a six-membered cyclic unsaturated hydrocarbon group with special stability and chemical activity. In this compound, chlorine, iodine and methyl are all substituents and are attached to different positions of the benzene ring. The chlorine atom and the iodine atom are both halogen elements, and the introduction of the benzene ring will affect the electron cloud distribution and chemical properties of the benzene ring. The methyl group is an alkyl group and has a electron supply effect, which also changes the reactivity and properties of the
These compounds are widely used in the field of organic synthesis, or can be used as intermediates, which can be converted into other more complex organic compounds through various chemical reactions, and are of great significance in many industries such as medicine, pesticides, and materials.
benzene ring is a six-membered cyclic unsaturated hydrocarbon group with special stability and chemical activity. In this compound, chlorine, iodine and methyl are all substituents and are attached to different positions of the benzene ring. The chlorine atom and the iodine atom are both halogen elements, and the introduction of the benzene ring will affect the electron cloud distribution and chemical properties of the benzene ring. The methyl group is an alkyl group and has a electron supply effect, which also changes the reactivity and properties of the
These compounds are widely used in the field of organic synthesis, or can be used as intermediates, which can be converted into other more complex organic compounds through various chemical reactions, and are of great significance in many industries such as medicine, pesticides, and materials.
What are the chemical properties of 1-chloro-3-iodo-2-methylbenzene?
1-Chloro-3-iodine-2-methylbenzene, an organic compound, has unique chemical properties and is worth studying in depth.
First of all, its halogenated hydrocarbon properties. Chlorine and iodine atoms are on the benzene ring, making this compound have a typical reaction of halogenated hydrocarbons. In the nucleophilic substitution reaction, due to the strong electronegativity of the halogen atom, the carbon-halogen bond electron cloud is biased towards the halogen atom, making the carbon atom partially positively charged and vulnerable to attack by nucleophiles. For example, in case of hydroxyl anion (OH), the halogen atom may be replaced by hydroxyl group to form the corresponding phenolic derivative; if it encounters cyanyl anion (CN), the halogen atom is replaced by cyanyl group, and the product can be further hydrolyzed to carboxylic acid, or reduced to amine.
Furthermore, the properties of the benzene ring are also critical. The benzene ring has a conjugated large π bond, which is rich in electrons, and is prone to electrophilic substitution reactions. Although methyl is an ortho-para-site group and chlorine and iodine are meta-site groups, under the combined action, the electron cloud density distribution on the benzene ring changes, and electrophilic reagents are more inclined to attack specific locations. If it reacts with mixed acids of nitric acid and sul And due to the coexistence of the electron-withdrawing induction effect of halogen atoms and the conjugation effect of benzene ring, the reactivity also changes compared with benzene.
And because of its methyl content, methyl has a certain electron donor property, which can affect the electron cloud density of the benzene ring, and methyl itself can react. Under light or heating conditions, the hydrogen atoms on methyl can be replaced by halogen free radicals, and free radical substitution reactions occur.
The functional groups and benzene ring structures contained in 1-chloro-3-iodine-2-methylbenzene exhibit various chemical properties, which are important in the field of organic synthesis and can be converted into a variety of useful organic compounds through many reactions.
First of all, its halogenated hydrocarbon properties. Chlorine and iodine atoms are on the benzene ring, making this compound have a typical reaction of halogenated hydrocarbons. In the nucleophilic substitution reaction, due to the strong electronegativity of the halogen atom, the carbon-halogen bond electron cloud is biased towards the halogen atom, making the carbon atom partially positively charged and vulnerable to attack by nucleophiles. For example, in case of hydroxyl anion (OH), the halogen atom may be replaced by hydroxyl group to form the corresponding phenolic derivative; if it encounters cyanyl anion (CN), the halogen atom is replaced by cyanyl group, and the product can be further hydrolyzed to carboxylic acid, or reduced to amine.
Furthermore, the properties of the benzene ring are also critical. The benzene ring has a conjugated large π bond, which is rich in electrons, and is prone to electrophilic substitution reactions. Although methyl is an ortho-para-site group and chlorine and iodine are meta-site groups, under the combined action, the electron cloud density distribution on the benzene ring changes, and electrophilic reagents are more inclined to attack specific locations. If it reacts with mixed acids of nitric acid and sul And due to the coexistence of the electron-withdrawing induction effect of halogen atoms and the conjugation effect of benzene ring, the reactivity also changes compared with benzene.
And because of its methyl content, methyl has a certain electron donor property, which can affect the electron cloud density of the benzene ring, and methyl itself can react. Under light or heating conditions, the hydrogen atoms on methyl can be replaced by halogen free radicals, and free radical substitution reactions occur.
The functional groups and benzene ring structures contained in 1-chloro-3-iodine-2-methylbenzene exhibit various chemical properties, which are important in the field of organic synthesis and can be converted into a variety of useful organic compounds through many reactions.
What are the main uses of 1-chloro-3-iodo-2-methylbenzene?
1-Chloro-3-iodine-2-methylbenzene is also an organic compound. Its main use is related to various fields of chemical industry.
In organic synthesis, this compound is often a key raw material. Due to its unique structure, chlorine, iodine and methyl each occupy a specific position, giving it special reactivity. Chlorine atoms can undergo nucleophilic substitution reactions, paving the way for the introduction of various functional groups. Iodine atoms are also non-idle. They participate in coupling reactions, such as the Ullmann reaction and the Suzuki reaction, which help to construct complex carbon-carbon and carbon-heteroaryl bond structures, contributing to the creation of novel organic molecular structures. The presence of methyl groups affects the electron cloud distribution and steric resistance of molecules, and has a subtle regulatory effect on the selectivity of the reaction and the configuration of the product.
In the field of materials science, 1-chloro-3-iodine-2-methylbenzene is also used. After appropriate chemical conversion, materials with specific photoelectric properties can be prepared. For example, through polymerization or copolymerization with other functional monomers, new conductive polymers or optically active materials can be obtained, which may have potential applications in electronic devices, such as organic Light Emitting Diodes, solar cells, etc., and can provide new ideas and options for material performance optimization.
Furthermore, in the field of medicinal chemistry, it can be used as an important intermediate for the synthesis of drug molecules. Through reasonable chemical modification and reaction, the introduction of groups related to biological activity is expected to create new drugs with unique pharmacological activities, which will contribute to human health. In short, 1-chloro-3-iodine-2-methylbenzene plays an indispensable role in many fields such as chemical industry, materials, and medicine, showing broad application prospects.
In organic synthesis, this compound is often a key raw material. Due to its unique structure, chlorine, iodine and methyl each occupy a specific position, giving it special reactivity. Chlorine atoms can undergo nucleophilic substitution reactions, paving the way for the introduction of various functional groups. Iodine atoms are also non-idle. They participate in coupling reactions, such as the Ullmann reaction and the Suzuki reaction, which help to construct complex carbon-carbon and carbon-heteroaryl bond structures, contributing to the creation of novel organic molecular structures. The presence of methyl groups affects the electron cloud distribution and steric resistance of molecules, and has a subtle regulatory effect on the selectivity of the reaction and the configuration of the product.
In the field of materials science, 1-chloro-3-iodine-2-methylbenzene is also used. After appropriate chemical conversion, materials with specific photoelectric properties can be prepared. For example, through polymerization or copolymerization with other functional monomers, new conductive polymers or optically active materials can be obtained, which may have potential applications in electronic devices, such as organic Light Emitting Diodes, solar cells, etc., and can provide new ideas and options for material performance optimization.
Furthermore, in the field of medicinal chemistry, it can be used as an important intermediate for the synthesis of drug molecules. Through reasonable chemical modification and reaction, the introduction of groups related to biological activity is expected to create new drugs with unique pharmacological activities, which will contribute to human health. In short, 1-chloro-3-iodine-2-methylbenzene plays an indispensable role in many fields such as chemical industry, materials, and medicine, showing broad application prospects.
What are 1-chloro-3-iodo-2-methylbenzene synthesis methods?
There are several common methods for the synthesis of 1-chloro-3-iodine-2-methylbenzene. First, it can be started from 2-methylaniline. Shilling 2-methylaniline reacts with hydrochloric acid and sodium nitrite at low temperature to obtain diazonium salts. The diazonium salts then react with cuprous chloride and hydrochloric acid to introduce chlorine atoms to obtain 2-methyl-3-chloroaniline. Subsequently, with a suitable oxidant, such as a mixed system of hydrogen peroxide and hydrochloric acid, the amino group is converted into an iodine atom, and the target product 1-chloro-3-iodine-2-methylbenzene can be obtained through this series of reactions.
Second, take o-xylene as the starting material. First, the halogenation reaction can be used. Under appropriate conditions, such as chlorine gas in the presence of light or initiator, the chlorination reaction can occur on the methyl group of o-xylene to obtain chloromethyl o-xylene. Then through nucleophilic substitution reaction, the chlorine atom is replaced by the iodine atom with the iodine source such as potassium iodide, and then the substituent is adjusted by oxidation or other suitable methods to finally synthesize 1-chloro-3-iodine-2-methylbenzene.
Another one uses m-chlorotoluene as the raw material. Under the action of appropriate catalysts, such as selecting specific metal catalysts and ligands, halogenation is carried out with an iodine source, and iodine atoms are directly introduced at specific positions of m-chlorotoluene to obtain 1-chloro-3-iodine-2-methyl benzene. This process requires fine regulation of reaction conditions, such as temperature, pressure, and reactant ratio, to ensure reaction selectivity and yield. The above methods have their own advantages and disadvantages, and the actual application needs to be based on specific needs and conditions.
Second, take o-xylene as the starting material. First, the halogenation reaction can be used. Under appropriate conditions, such as chlorine gas in the presence of light or initiator, the chlorination reaction can occur on the methyl group of o-xylene to obtain chloromethyl o-xylene. Then through nucleophilic substitution reaction, the chlorine atom is replaced by the iodine atom with the iodine source such as potassium iodide, and then the substituent is adjusted by oxidation or other suitable methods to finally synthesize 1-chloro-3-iodine-2-methylbenzene.
Another one uses m-chlorotoluene as the raw material. Under the action of appropriate catalysts, such as selecting specific metal catalysts and ligands, halogenation is carried out with an iodine source, and iodine atoms are directly introduced at specific positions of m-chlorotoluene to obtain 1-chloro-3-iodine-2-methyl benzene. This process requires fine regulation of reaction conditions, such as temperature, pressure, and reactant ratio, to ensure reaction selectivity and yield. The above methods have their own advantages and disadvantages, and the actual application needs to be based on specific needs and conditions.
1-chloro-3-iodo-2-methylbenzene what are the precautions during storage and transportation?
1-Chloro-3-iodine-2-methylbenzene is one of the organic compounds. During storage and transportation, many matters must be paid attention to.
Bear the brunt, because it has a certain chemical activity, it should be stored in a cool, dry and well-ventilated place. This is to avoid the risk of chemical reaction and deterioration due to temperature and humidity discomfort. Do not be near fire or heat sources, cover it or be flammable or react violently with heat, causing the risk of fire or explosion.
Furthermore, it should be stored away from oxidants. The edge oxidant is easy to oxidize with 1-chloro-3-iodine-2-methylbenzene, resulting in impure products, and the reaction may be rapid, endangering safety.
Packaging is also crucial. A well-sealed container must be used to prevent leakage. If the package is damaged, it will evaporate gas or pollute the environment, and be harmful to human health.
When transporting, the vehicle should be selected with the corresponding qualifications. During transportation, it must be ensured that it is smooth and protected from violent vibration and impact, so as to avoid damage to the package and leakage of materials.
The escort personnel also need to have professional training, familiar with the characteristics of 1-chloro-3-iodine-2-methylbenzene and the emergency treatment method. In case of leakage and other emergencies, it can be disposed of quickly and properly to reduce the damage.
During loading and unloading, the operation should be light and not brutal. To prevent the package from breaking during loading and unloading, resulting in material leakage. And the loading and unloading site should be equipped with corresponding emergency equipment and protective equipment to deal with emergencies.
Bear the brunt, because it has a certain chemical activity, it should be stored in a cool, dry and well-ventilated place. This is to avoid the risk of chemical reaction and deterioration due to temperature and humidity discomfort. Do not be near fire or heat sources, cover it or be flammable or react violently with heat, causing the risk of fire or explosion.
Furthermore, it should be stored away from oxidants. The edge oxidant is easy to oxidize with 1-chloro-3-iodine-2-methylbenzene, resulting in impure products, and the reaction may be rapid, endangering safety.
Packaging is also crucial. A well-sealed container must be used to prevent leakage. If the package is damaged, it will evaporate gas or pollute the environment, and be harmful to human health.
When transporting, the vehicle should be selected with the corresponding qualifications. During transportation, it must be ensured that it is smooth and protected from violent vibration and impact, so as to avoid damage to the package and leakage of materials.
The escort personnel also need to have professional training, familiar with the characteristics of 1-chloro-3-iodine-2-methylbenzene and the emergency treatment method. In case of leakage and other emergencies, it can be disposed of quickly and properly to reduce the damage.
During loading and unloading, the operation should be light and not brutal. To prevent the package from breaking during loading and unloading, resulting in material leakage. And the loading and unloading site should be equipped with corresponding emergency equipment and protective equipment to deal with emergencies.
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