Linshang Chemical
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1-Chloro-3-Isocyanato-Benzene
Linshang Chemical
|
HS Code |
366111 |
| Chemical Formula | C7H4ClNO |
| Molar Mass | 153.565 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 235 - 237 °C |
| Density | 1.24 g/cm³ |
| Solubility | Insoluble in water, soluble in organic solvents |
| Flash Point | 105 °C |
| Stability | Stable under normal conditions, reacts with water, alcohols, amines |
As an accredited 1-Chloro-3-Isocyanato-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 3 - isocyanato - benzene in 1 - kg bottles, securely packaged for safe transit. |
| Storage | 1 - Chloro - 3 - isocyanato - benzene should be stored in a cool, well - ventilated area, away from sources of heat and ignition. Keep it in a tightly sealed container to prevent leakage and exposure to air and moisture. Store it separately from incompatible substances like amines, alcohols, and acids. Adequate safety precautions such as signage and proper handling procedures should be in place near the storage area. |
| Shipping | 1 - Chloro - 3 - isocyanato - benzene is a hazardous chemical. It must be shipped in accordance with strict regulations. Packed in suitable, leak - proof containers, transported by approved carriers with proper labeling and documentation for safety. |
Competitive 1-Chloro-3-Isocyanato-Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 1-Chloro-3-Isocyanato-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-chloro-3-isocyanato-benzene?
1-Chloro-3-isocyanate phenyl ester, an organic compound, is widely used in the chemical industry.
Its primary use is as an intermediate in organic synthesis. With its unique chemical structure, 1-chloro-3-isocyanate phenyl ester can participate in many organic reactions to prepare a variety of organic compounds with different functions. For example, isocyanate groups are extremely active functional groups that can react with compounds containing active hydrogen, such as alcohols and amines. When reacted with alcohols, carbamate compounds can be formed, which are important in the fields of medicine, pesticides, and polymer materials. In the field of medicine, some urethane compounds have unique biological activities and can be used as pharmaceutical intermediates to synthesize drugs with specific curative effects; in the field of pesticides, some urethane compounds can be used as insecticides, fungicides, etc. When 1-chloro-3-isocyanate phenyl ester reacts with amines, urea compounds will be formed, and urea compounds also show important value in many fields. For example, in the synthesis of plastics, rubber and other polymer materials, urea compounds can be used as cross-linking agents or modifiers to improve the properties of materials.
Furthermore, 1-chloro-3-isocyanate phenyl esters are also of great significance in the preparation of polymer materials. Through proper polymerization, it can participate in the synthesis process of polymer. For example, by polymerizing it with compounds such as polyols, polyurethane materials with specific properties can be prepared. Polyurethane materials are widely used in foam plastics, elastomers, coatings, adhesives and many other fields. Foam plastics can be used for heat insulation, sound insulation and buffer packaging; elastomers can be used to make shoe soles, seals, etc.; coatings and adhesives play a key role in construction, automotive and other industries.
In addition, 1-chloro-3-isocyanate phenyl ester also plays an important role in the production of fine chemical products. It can be converted into fine chemicals with special functions through a series of chemical reactions, such as for the synthesis of dyes, pigments, fragrances, etc., providing important raw material support for these fields, thus helping to produce colorful dyes and pigments, as well as fragrance products with unique aromas.
Its primary use is as an intermediate in organic synthesis. With its unique chemical structure, 1-chloro-3-isocyanate phenyl ester can participate in many organic reactions to prepare a variety of organic compounds with different functions. For example, isocyanate groups are extremely active functional groups that can react with compounds containing active hydrogen, such as alcohols and amines. When reacted with alcohols, carbamate compounds can be formed, which are important in the fields of medicine, pesticides, and polymer materials. In the field of medicine, some urethane compounds have unique biological activities and can be used as pharmaceutical intermediates to synthesize drugs with specific curative effects; in the field of pesticides, some urethane compounds can be used as insecticides, fungicides, etc. When 1-chloro-3-isocyanate phenyl ester reacts with amines, urea compounds will be formed, and urea compounds also show important value in many fields. For example, in the synthesis of plastics, rubber and other polymer materials, urea compounds can be used as cross-linking agents or modifiers to improve the properties of materials.
Furthermore, 1-chloro-3-isocyanate phenyl esters are also of great significance in the preparation of polymer materials. Through proper polymerization, it can participate in the synthesis process of polymer. For example, by polymerizing it with compounds such as polyols, polyurethane materials with specific properties can be prepared. Polyurethane materials are widely used in foam plastics, elastomers, coatings, adhesives and many other fields. Foam plastics can be used for heat insulation, sound insulation and buffer packaging; elastomers can be used to make shoe soles, seals, etc.; coatings and adhesives play a key role in construction, automotive and other industries.
In addition, 1-chloro-3-isocyanate phenyl ester also plays an important role in the production of fine chemical products. It can be converted into fine chemicals with special functions through a series of chemical reactions, such as for the synthesis of dyes, pigments, fragrances, etc., providing important raw material support for these fields, thus helping to produce colorful dyes and pigments, as well as fragrance products with unique aromas.
What are the physical properties of 1-chloro-3-isocyanato-benzene?
1-Chloro-3-isocyanate benzene is a kind of organic compound. Its physical properties are quite unique, and this is for you to describe in detail.
First of all, its appearance, at room temperature, 1-chloro-3-isocyanate benzene is often colorless to light yellow liquid, clear and with a certain degree of fluidity. Looking at its color, it is like a light yellow morning light, revealing its unique chemical nature.
Second time on its smell, this compound emits a pungent and strong irritating smell. If people smell it, they will feel uncomfortable in the nose and throat. This smell is like a warning bell, warning everyone that it is dangerous.
As for the boiling point, the boiling point of 1-chloro-3-isocyanate benzene is quite high, about 200 degrees Celsius. Such a high boiling point indicates that the intermolecular force is strong, and a higher temperature is required to transform it from liquid to gaseous. Just like breaking through many barriers, it can reach the state of gasification.
In terms of melting point, it is usually in a relatively low temperature range, about minus several degrees Celsius. This property makes it stable as a liquid at room temperature. Like ice and snow melting under the warm sun, this compound turns into a flexible liquid when it is slightly above its melting point.
Furthermore, its density is greater than that of water. If it is placed in one place with water, it will sink like a heavy object and sink to the bottom of the water. This density characteristic is of important guiding significance in many chemical operations and separation processes.
Solubility is also one of its important physical properties. 1-chloro-3-isocyanate benzene is insoluble in water, but it shows good solubility in most organic solvents. Organic solvents such as ethanol, ether, and acetone can disperse it uniformly, just like a wanderer returning home, and blend seamlessly.
First of all, its appearance, at room temperature, 1-chloro-3-isocyanate benzene is often colorless to light yellow liquid, clear and with a certain degree of fluidity. Looking at its color, it is like a light yellow morning light, revealing its unique chemical nature.
Second time on its smell, this compound emits a pungent and strong irritating smell. If people smell it, they will feel uncomfortable in the nose and throat. This smell is like a warning bell, warning everyone that it is dangerous.
As for the boiling point, the boiling point of 1-chloro-3-isocyanate benzene is quite high, about 200 degrees Celsius. Such a high boiling point indicates that the intermolecular force is strong, and a higher temperature is required to transform it from liquid to gaseous. Just like breaking through many barriers, it can reach the state of gasification.
In terms of melting point, it is usually in a relatively low temperature range, about minus several degrees Celsius. This property makes it stable as a liquid at room temperature. Like ice and snow melting under the warm sun, this compound turns into a flexible liquid when it is slightly above its melting point.
Furthermore, its density is greater than that of water. If it is placed in one place with water, it will sink like a heavy object and sink to the bottom of the water. This density characteristic is of important guiding significance in many chemical operations and separation processes.
Solubility is also one of its important physical properties. 1-chloro-3-isocyanate benzene is insoluble in water, but it shows good solubility in most organic solvents. Organic solvents such as ethanol, ether, and acetone can disperse it uniformly, just like a wanderer returning home, and blend seamlessly.
What is the chemistry of 1-chloro-3-isocyanato-benzene?
1-Chloro-3-isocyanate benzene, this is an organic compound with unique chemical properties. In its structure, the chlorine atom and the isocyanate are connected to the benzene ring.
Let's talk about the chlorine atom first, which has electron-absorbing properties, causing the electron cloud density of the benzene ring to decrease, so that the electrophilic substitution reaction activity of the benzene ring is weakened. Such as halogenation reaction, nitration reaction, etc., compared with benzene, the reaction conditions of 1-chloro-3-isocyanate benzene are more severe and the rate is slower.
Let's talk about isocyanate, its chemical properties are active. The carbon and nitrogen double bonds in isocyanate are electrophilic and easy to react with nucleoph When exposed to water, it hydrolyzes rapidly to form carbon dioxide and amine compounds. When it encounters alcohols, an alcoholysis reaction occurs to form carbamate. With amines, an aminolysis reaction occurs to form urea compounds.
Because of its active chemical properties, 1-chloro-3-isocyanate benzene is widely used in the field of organic synthesis and can be used as an intermediate for the preparation of drugs, pesticides and polymer materials. However, because of its activity, it must be handled with caution when storing and using, and avoid contact with easily reactive substances such as water, alcohol and amine to prevent uncontrolled reactions and safety accidents. At the same time, the compound has certain toxicity and irritation, and protective measures are taken during operation to ensure personal safety and environmental pollution.
Let's talk about the chlorine atom first, which has electron-absorbing properties, causing the electron cloud density of the benzene ring to decrease, so that the electrophilic substitution reaction activity of the benzene ring is weakened. Such as halogenation reaction, nitration reaction, etc., compared with benzene, the reaction conditions of 1-chloro-3-isocyanate benzene are more severe and the rate is slower.
Let's talk about isocyanate, its chemical properties are active. The carbon and nitrogen double bonds in isocyanate are electrophilic and easy to react with nucleoph When exposed to water, it hydrolyzes rapidly to form carbon dioxide and amine compounds. When it encounters alcohols, an alcoholysis reaction occurs to form carbamate. With amines, an aminolysis reaction occurs to form urea compounds.
Because of its active chemical properties, 1-chloro-3-isocyanate benzene is widely used in the field of organic synthesis and can be used as an intermediate for the preparation of drugs, pesticides and polymer materials. However, because of its activity, it must be handled with caution when storing and using, and avoid contact with easily reactive substances such as water, alcohol and amine to prevent uncontrolled reactions and safety accidents. At the same time, the compound has certain toxicity and irritation, and protective measures are taken during operation to ensure personal safety and environmental pollution.
What are 1-chloro-3-isocyanato-benzene synthesis methods?
There are many ways to synthesize 1-chloro-3-isocyanate-benzene. First, it can be started from m-chloroaniline. Shilling m-chloroaniline reacts with phosgene, and this reaction needs to be carried out at a specific temperature and in a suitable solvent. Phosgene has strong activity. When it meets m-chloroaniline, the hydrogen on the amine group is replaced. After a series of reactions, the target product 1-chloro-3-isocyanate-benzene can be obtained. During the reaction, factors such as temperature and phosgene dosage need to be precisely controlled, otherwise the yield and purity will be affected.
Second, m-chlorobenzoic acid can also be used as the starting material. First, m-chlorobenzoic acid is converted into m-chlorobenzoyl chloride, which can be achieved by sulfinyl chloride and other reagents. Then m-chlorobenzoyl chloride reacts with urea and is gradually converted into 1-chloro-3-isocyanate-benzene under heating and other conditions. In this path, the reaction conditions at each step are also very critical, such as reaction temperature, reaction time and the proportion of reactants.
Furthermore, m-chloro-nitrobenzene can also be used as the starting material. First, m-chloro-nitrobenzene is reduced to m-chloroaniline. The commonly used reducing agents are iron and hydrochloric acid. After obtaining m-chloroaniline, 1-chloro-3-isocyanate-benzene is synthesized according to the above reaction with phosgene. In this process, the reduction step needs to pay attention to the mild reaction conditions to avoid side reactions such as excessive reduction.
All these synthesis methods have advantages and disadvantages. In practical application, the appropriate synthesis path should be carefully selected according to factors such as the availability of raw materials, cost, difficulty in controlling reaction conditions, and requirements for product purity.
Second, m-chlorobenzoic acid can also be used as the starting material. First, m-chlorobenzoic acid is converted into m-chlorobenzoyl chloride, which can be achieved by sulfinyl chloride and other reagents. Then m-chlorobenzoyl chloride reacts with urea and is gradually converted into 1-chloro-3-isocyanate-benzene under heating and other conditions. In this path, the reaction conditions at each step are also very critical, such as reaction temperature, reaction time and the proportion of reactants.
Furthermore, m-chloro-nitrobenzene can also be used as the starting material. First, m-chloro-nitrobenzene is reduced to m-chloroaniline. The commonly used reducing agents are iron and hydrochloric acid. After obtaining m-chloroaniline, 1-chloro-3-isocyanate-benzene is synthesized according to the above reaction with phosgene. In this process, the reduction step needs to pay attention to the mild reaction conditions to avoid side reactions such as excessive reduction.
All these synthesis methods have advantages and disadvantages. In practical application, the appropriate synthesis path should be carefully selected according to factors such as the availability of raw materials, cost, difficulty in controlling reaction conditions, and requirements for product purity.
1-chloro-3-isocyanato-benzene what are the precautions during use
For 1-chloro-3-isocyanate benzene, all precautions should not be ignored when using it. This substance is quite toxic and irritating, and can cause damage to the human body if it touches the skin, inhales its vapor or drinks it by mistake. Therefore, when operating, be sure to wear complete protective equipment, such as gas masks, protective gloves and protective clothing, to protect yourself.
In addition, 1-chloro-3-isocyanate benzene is chemically active and easily reacts with water, alcohols, amines and many other substances. Therefore, when storing, it is necessary to choose a dry, cool and well-ventilated place, and it must be isolated from the above-mentioned easily reactive substances to prevent unexpected chemical reactions.
During use, attention should also be paid to the precise control of the reaction conditions. Because the reactions involved require specific temperatures, pressures and catalysts, etc., a slight difference may affect the process of the reaction and the quality of the product, or even cause danger.
In addition, after use, the remaining 1-chloro-3-isocyanate biphenyl and related waste must not be discarded at will, and must be properly disposed of in accordance with relevant regulations to prevent pollution and harm to the environment. Overall, the use of this substance should be done with caution and strict procedures to ensure safety.
In addition, 1-chloro-3-isocyanate benzene is chemically active and easily reacts with water, alcohols, amines and many other substances. Therefore, when storing, it is necessary to choose a dry, cool and well-ventilated place, and it must be isolated from the above-mentioned easily reactive substances to prevent unexpected chemical reactions.
During use, attention should also be paid to the precise control of the reaction conditions. Because the reactions involved require specific temperatures, pressures and catalysts, etc., a slight difference may affect the process of the reaction and the quality of the product, or even cause danger.
In addition, after use, the remaining 1-chloro-3-isocyanate biphenyl and related waste must not be discarded at will, and must be properly disposed of in accordance with relevant regulations to prevent pollution and harm to the environment. Overall, the use of this substance should be done with caution and strict procedures to ensure safety.
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