1-Chloro-4-Ethenylbenzene
Linshang Chemical
HS Code |
334565 |
Chemical Formula | C8H7Cl |
Molar Mass | 138.594 g/mol |
Appearance | Colorless to light - yellow liquid |
Odor | Aromatic odor |
Density | 1.069 g/cm³ at 20 °C |
Boiling Point | 197 - 199 °C |
Melting Point | -34 °C |
Solubility In Water | Insoluble in water |
Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
Flash Point | 71 °C |
Vapor Pressure | 0.13 kPa at 25 °C |
Refractive Index | 1.562 at 20 °C |
As an accredited 1-Chloro-4-Ethenylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 - chloro - 4 - ethenylbenzene in 5 - liter containers, well - sealed for chemical storage. |
Storage | 1 - Chloro - 4 - ethenylbenzene should be stored in a cool, well - ventilated area, away from direct sunlight and heat sources. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, strong acids, and bases. Adhere to proper labeling and ensure storage facilities comply with safety regulations to minimize risks. |
Shipping | 1 - Chloro - 4 - ethenylbenzene is a chemical. Ship it in well - sealed, corrosion - resistant containers. Follow all hazardous material shipping regulations, ensuring proper labeling and documentation for safe transport. |
Competitive 1-Chloro-4-Ethenylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 1-Chloro-4-Ethenylbenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Ammonia is a colorless gas at room temperature and pressure, with a strong irritating odor. Its density is less than that of air, and it is highly soluble in water, forming ammonia monohydrate, which is weakly alkaline. Its melting point is -77.7 ° C and boiling point is -33.35 ° C. Due to the existence of hydrogen bonds between molecules, the melting boiling point is higher than that of cyclic hydrides. Ammonia is reductive and can react with oxidants such as oxygen under certain conditions.
As for "4-ethylfuranyl silicon", this may be an organic compound containing silicon. Usually silicon-containing organics have a certain degree of thermal stability and chemical stability. Silicon atoms are introduced into the organic structure or affect the polarity of molecules. If the molecular structure is symmetrical and the polarity is small, the solubility may be better in non-polar solvents; conversely, if the polarity is large, the solubility is better in polar solvents. Its physical properties are also affected by the interaction of various groups in the molecule. The melting point and boiling point of "4-ethylfuranyl silicon" are restricted by the intermolecular force. If the molecular weight is large and the intermolecular force is strong, the melting boiling point is high. And because it contains unsaturated furan ring, it has certain chemical activity and can participate in addition and substitution reactions, while the presence of ethyl groups may affect the reaction activity and selectivity.
First, due to the ether bond, 1 + -tritium-4-ethylphenyl ether is relatively chemically stable. In the ether bond, the oxygen atom is connected to the two hydrocarbon groups, and this structure gives it a certain inertness. Under normal conditions at room temperature, it is relatively stable to many common reagents, such as dilute acids and dilute bases, and it is not easy to react with them. However, under certain conditions, such as the presence of strong acids and heating, ether bonds can be cracked. This is because the strong acid can protonate the oxygen atom of the ether bond, enhance the polarity of the carbon-oxygen bond, and cause it to break more easily.
Second, the hydrocarbyl part of the compound also affects its properties. The presence of ethyl and phenyl groups endows 1 + -tritium-4-ethylphenyl ether with certain lipid solubility and aromaticity. Phenyl groups have a conjugated system, which makes the molecule have certain stability and can participate in aromatic electrophilic substitution reactions. For example, when encountering electrophilic reagents, such as halogens, nitro positive ions, etc., substitution reactions can occur at specific positions in the benzene ring. Ethyl increases the lipid solubility of the molecule and affects its solubility in different solvents.
Furthermore, due to the existence of tritium, 1 + -tritium-4-ethylphenyl ether is radioactive. Tritium is a radioactive isotope of hydrogen, which gives the compound special tracer properties. In the field of scientific research, its radioactivity can be used to track the traces of compounds in chemical reactions, metabolism in vivo, etc., providing powerful means for studying reaction mechanisms and material metabolic pathways.
The chemical properties of 1 + -tritium-4-ethylphenyl ether are not only derived from the ether bond and hydrocarbon group in its molecular structure, but also influenced by the special atom of tritium, which is of great significance in organic synthesis and scientific research tracer.
It is often used as a raw material for organic synthesis in the field of material preparation. It has a unique structure and can be converted into various materials with special properties through various chemical reactions. For example, through a specific reaction path, it can be combined with other compounds to obtain new types of polymer. Such polymers may have excellent mechanical properties and thermal stability. They can be used as high-performance structural materials in aerospace, automobile manufacturing and other industries, adding to the stability and durability of equipment.
In the field of medicinal chemistry, 1 + -deuterium-4-ethylphenyl ether is also of great value. It can be used as a drug intermediate to construct a bioactive molecular structure through chemical modification and transformation. Doctors can use this to develop new drugs to fight various diseases, such as certain inflammation, chronic diseases, etc., for human health and well-being.
In addition, in the fragrance industry, due to its own unique chemical composition, it may be able to derive different odor molecules. According to its characteristics, perfumers can prepare unique fragrances for use in perfumes, air fresheners and other products to add fragrance to life.
And in the field of electronics industry, it may be able to participate in the preparation of electronic materials. After specific processing, the material can have specific electrical properties, such as good insulation and moderate conductivity, etc., to provide protection for the stable operation of electronic components, and to help the development and innovation of electronic equipment.
All these all highlight the importance of 1 + -deuterium-4-ethylphenyl ether in various industrial applications, which makes great contributions to the progress and development of various industries.
First, start with anisole and halogenate it first. With the help of appropriate temperature and catalyst, the anisole is interacted with bromine to obtain brominated anisole. In this step, the temperature and the amount of bromine need to be controlled to avoid polybromination. Then the brominated anisole and ethylation reagents, such as haloethane and suitable bases, are stored in the phase transfer catalyst for nucleophilic substitution. The base can pull hydrogen, so that the oxygen anion of bromoanisole is formed, and then interact with haloethane to obtain 1-bromo-4-ethyl anisole.
Second, starting from 4-ethyl anisole. The 4-ethyl anisole is placed in a suitable solvent, and a brominating agent, such as N-bromosuccinimide (NBS), is added to the initiator, such as benzoyl peroxide, to carry out a free radical bromination reaction. The initiator is decomposed into a free radical by heat, grabs the hydrogen at the benzyl position of 4-ethylanisole, generates benzyl radical, and then interacts with NBS to obtain the target 1-bromo-4-ethylanisole. This way, the selectivity is good, the hydrogen at the benzyl position is active, and it is easy to be brominated.
Third, p-bromophenyl ether is prepared by p-bromophenol and haloethane. In an alkaline environment, such as sodium hydroxide solution, the phenolic hydroxyl negative ion is nucleophilically substituted with haloethane to form an ether bond. After methylation reagents, such as dimethyl sulfate, under the catalysis of alkali, the oxymethylation of phenolic hydroxyl group, the final product is 1-bromo-4-ethylanisole.
All these methods have advantages and disadvantages. Depending on the availability of raw materials, cost and yield, the best method is selected.
1-Bromo-4-isopropylbenzene, in the environment, its harm should not be underestimated. Its chemical properties are relatively stable, and if it accidentally enters the water body, it is difficult to degrade rapidly and naturally. Drifting with water will pollute the water source and deteriorate the living environment of aquatic organisms. Water is the source of all things. Aquatic organisms suffer from it, and the food chain is also destroyed. Many organisms that rely on aquatic organisms for food will be affected by it, and the ecological balance may be seriously disturbed.
As for soil, if contaminated with this substance, it will change the physical and chemical properties of the soil, affect the activities of soil microorganisms, and then hinder the absorption of nutrients by plant roots, resulting in poor plant growth, reduced vegetation coverage, and increased risk of soil erosion.
For humans, if 1-bromo-4-isopropylbenzene enters the human body through the respiratory tract, it will irritate the respiratory mucosa and cause uncomfortable symptoms such as cough and asthma. Long-term exposure may cause damage to lung function, and the ventilation and ventilation functions of the lungs may be affected, making people susceptible to respiratory diseases.
If exposed to the skin, it may cause skin allergic reactions, such as erythema, itching, rash, etc. In severe cases, the skin barrier function is damaged, and it is more susceptible to other harmful substances.
If accidentally ingested, it will damage the digestive system, cause nausea, vomiting, abdominal pain and other symptoms, and even cause damage to important organs such as the liver and kidneys. Because of its metabolites, it may affect the normal function of organs.
In short, 1-bromo-4-isopropylbenzene has potential harm to the environment and people. During daily production and use, it is necessary to treat it with caution and strengthen protection and control to reduce its harm.
Chlorine atoms have an electron-absorbing effect. This electron-absorbing property can affect the electron cloud density distribution of the benzene ring in chemical reactions. The electron cloud density of the adjacent and para-sites of the benzene ring is relatively reduced, and the electron cloud density of the meta-site is relatively increased. When it is an electrophilic substitution reaction, its reactivity is different from that of benzene, and the substituent entry is also affected by this.
Vinyl, containing a carbon-carbon double bond, which is electron-rich and nucleophilic. Therefore, 1-chloro-4-vinylbenzene can participate in the addition reaction. If it is combined with bromine, under appropriate conditions, the carbon-carbon double bond can be added to bromine, the double bond is broken, and the bromine atom is added to the carbon atom at both ends of the double bond, resulting in the product of dibromine substitution.
Furthermore, the benzene ring forms a conjugated system with the vinyl group, which enhances the stability of the molecule. This conjugation effect also affects the physical and chemical properties of the compound. In terms of spectral properties, its ultraviolet absorption spectrum must have characteristic performance. And due to the existence of the conjugated system, the intra-molecular electrons are delocalized, which affects its reactivity and reaction path.
1-chloro-4-vinylbenzene Under basic conditions, the chlorine atom can be replaced by nucleophilic reagents. Nucleophilic reagents such as hydroxyl negative ions can attack carbon atoms connected to chlorine, and chlorine leaves in the form of chloride ions to produce 4-vinylphenol products.
It is an important intermediate in organic synthesis. It can be used for various reactions to construct more complex organic molecular structures to meet the needs of medicine, materials and other fields.
p-chlorobenzene is a key raw material for organic synthesis. In the field of polymer materials, chlorine-containing polystyrene polymers can be prepared by polymerization. Due to the introduction of chlorine atoms, these polymers have unique properties, such as improved flame retardancy, which can be widely used in the shell materials of electronic and electrical products, providing fire protection for electronic equipment and reducing fire hazards.
Furthermore, it also plays an important role in the synthesis of pharmaceutical intermediates. With the help of a series of chemical reactions, it can be converted into compounds with specific structures. These compounds are used as pharmaceutical intermediates to further synthesize drugs for the treatment of various diseases, such as some anti-cancer drugs with special pharmacological activities.
In addition, in the coating industry, p-chlorobenzene can be used as a modified monomer to participate in the synthesis of coating resins. The modified coatings have significantly enhanced their hardness, wear resistance and chemical resistance. They are widely used in surface coating in construction, automotive and other industries to provide long-term protection and aesthetic decoration for objects.
In the field of fragrance synthesis, p-chlorobenzene can be used as a starting material to construct compounds with unique aroma structures through multi-step reactions, enriching the variety of fragrances, and are used to prepare various perfumes, air fresheners and other products, giving them a unique smell.
To sum up, 1-chloro-4-ethenylbenzene plays an indispensable role in many fields of chemical industry, greatly promoting the development and progress of related industries.
First, it starts with p-chlorotoluene, chlorinates through the side chain to obtain p-chlorobenzyl chloride, and then co-heats with the alkali solution to dehydrochloride, which can form 1-chloro-4-vinylbenzene. This step is slightly complicated, but the raw materials are easy to obtain. First, with the help of light or initiator, p-chlorotoluene interacts with chlorine gas, and the side chain hydrogen is chlorinated to obtain p-chlorobenzyl chloride. Then it is co-heated with the sodium hydroxide alcohol solution to eliminate the reaction, and the hydrogen chloride is removed to obtain the target product.
Second, 1-chloro-4-vinylbenzene can be prepared by the reaction of p-chlorobenzaldehyde with triphenylphosphinomethyl, that is, the Wittig reaction. The reaction conditions are mild and the yield is quite high. The reaction of p-chlorobenzaldehyde with triphenylphosphinomethyl reagent in an appropriate solvent is obtained by nucleophilic addition and elimination. Triphenylphosphinomethyl reagent can be prepared from triphenylphosphine and halomethane first to produce ylide, and then reacted with alkali to form it.
Third, using p-chlorobrombenzene as raw material, through Grignard reaction, p-chlorophenyl magnesium bromide is first prepared, and then reacts with acetylene derivatives to obtain 1-chloro-4-vinylbenzene. This route requires an anhydrous and oxygen-free environment, which requires strict operation. First, p-chlorobrombenzene and magnesium chips are reacted in anhydrous ether or tetrahydrofuran to prepare p-chlorophenyl magnesium bromide Grignard reagent. Then it reacts with suitable acetylene derivatives, such as magnesium acetylene bromide, and undergoes a series of transformations to generate 1-chloro-4-vinylbenzene.
The first thing to pay attention to is its characteristics. This is a colorless liquid with a special odor, flammable and irritating, and is a dangerous chemical. Because of its flammability, it is easy to burn in case of open flames and hot topics, so the storage place must be kept away from fire and heat sources. Smoking is strictly prohibited, and explosion-proof lighting and ventilation facilities should be used. All equipment must be grounded to prevent static electricity from accumulating and causing fires.
Furthermore, it is irritating, irritating to the eyes, respiratory tract and skin, and can endanger human health. The storage area should be kept cool and ventilated to avoid leakage caused by the increase in temperature and pressure caused by direct sunlight. The container must be well sealed to prevent leakage from escaping. When handling, it should be handled lightly. Do not collide or invert to prevent damage to the container.
In addition, because it is a hazardous chemical, storage and transportation must follow relevant regulations. The storage site needs to be licensed and meet safety standards, and the operator must be professionally trained and operate according to the specifications. When transporting, it should follow the prescribed route, do not stop in densely populated areas and open flames, and be equipped with corresponding emergency treatment equipment and protective equipment.
In the event of a leak, personnel should be quickly evacuated to a safe area and the source of fire should be cut off. Emergency response personnel must wear gas masks and protective clothing, and do not touch the leak. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be built embankments or dug for containment, covered with foam to reduce vapor disasters, and then transferred to tankers or special containers with explosion-proof pumps for recycling or harmless treatment. In this way, the safety of 1-chloro-4-vinylbenzene during storage and transportation can be ensured.
At the environmental end, it has a certain volatility and can enter the atmosphere, undergo photochemical reactions, or cause ozone and other secondary pollutants to form, which in turn affects air quality. It may also remain in soil and water bodies, poisoning soil microorganisms and aquatic organisms. In soil, it may interfere with the normal metabolism and reproduction of microorganisms, destroying soil ecological balance; in water bodies, it has adverse effects on the growth, development and reproduction of aquatic organisms such as fish and plankton. In severe cases, it can cause biological death and destroy the structure and function of aquatic ecosystems.
As for human health, 1-chloro-4-vinylbenzene enters the human body through respiratory tract, skin contact or accidental ingestion. Excessive inhalation can irritate the respiratory tract, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure may damage the nervous system, causing headaches, dizziness, fatigue, insomnia and other neurasthenia. And it may have potential carcinogenicity. Although relevant studies have not been conclusive, long-term exposure to this substance environment may increase the risk of cancer. Skin contact can cause skin allergies, itching, redness, etc. If accidentally ingested, it can irritate the gastrointestinal tract, causing nausea, vomiting, abdominal pain and other symptoms.
In summary, 1-chloro-4-vinylbenzene poses a potential threat to the environment and human health. During production and use, it needs to be properly protected and handled to reduce its harm.

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