1-Chloro-4-Ethylsulfonyl-2-Nitrobenzene
Linshang Chemical
HS Code |
542507 |
Chemical Formula | C8H8ClNO4S |
Molar Mass | 265.67 g/mol |
Appearance | Solid (usually yellowish) |
Melting Point | Data depends on purity (approx. in a certain range) |
Boiling Point | Decomposes before boiling (usually) |
Solubility In Water | Low solubility in water |
Solubility In Organic Solvents | Soluble in some organic solvents like dichloromethane |
Density | Data may vary with purity |
Vapor Pressure | Very low vapor pressure |
Stability | Stable under normal conditions, but reactive with strong oxidizing agents |
As an accredited 1-Chloro-4-Ethylsulfonyl-2-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 1 - chloro - 4 - ethylsulfonyl - 2 - nitrobenzene packaged in a sealed, corrosion - resistant container. |
Storage | 1 - Chloro - 4 - ethylsulfonyl - 2 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from sources of heat, ignition, and incompatible substances such as strong oxidizing agents and bases. Store in a tightly - sealed container to prevent leakage and exposure to air and moisture, which could potentially lead to decomposition or reactivity issues. |
Shipping | 1 - Chloro - 4 - ethylsulfonyl - 2 - nitrobenzene is shipped in tightly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling and secure handling during transit to prevent any leakage or risks. |
Competitive 1-Chloro-4-Ethylsulfonyl-2-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1-Chloro-4-Ethylsulfonyl-2-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
It also has important uses in the field of materials science. Or it can be used to prepare special functional materials, such as materials with unique electrical, optical or thermal properties. After ingenious design and synthesis, it can be integrated into the molecular structure of the material, which can significantly improve the properties of the material to meet the needs of different application scenarios.
Furthermore, in the field of pesticide synthesis, this compound also plays an important role. It can be used as a key intermediate for the synthesis of highly efficient, low toxic and environmentally friendly pesticides. Through chemical modification and structural optimization, pesticide varieties with high selectivity and strong inhibitory activity against specific pests or pathogens can be created, providing a powerful means for pest control in agricultural production.
In summary, 1-chloro-4-ethylsulfonyl-2-nitrobenzene has shown important application value in many fields such as drugs, materials and pesticides due to its special chemical structure, providing an indispensable material basis for scientific research and industrial development in related fields.
Looking at its properties, it is mostly solid at room temperature, which is caused by intermolecular forces. The determination of its melting point is crucial for identification and purity determination. The melting point of this compound with different purity varies slightly. According to past experiments, the melting point of pure 1-chloro-4-ethanesulfonyl-2-nitrobenzene is within a certain temperature range, which is obtained by repeated accurate measurement.
As for the boiling point, it is not easy to accurately determine its boiling point because the compound is heated or threatened to decompose. However, under suitable conditions, its approximate boiling point range can also be estimated.
In terms of solubility, the compound exhibits specific solubility characteristics in organic solvents. Common organic solvents such as ethanol and acetone have a certain solubility to it. However, in water, its solubility is extremely low, because its molecular structure has few hydrophilic groups and many hydrophobic parts, so it is difficult to dissolve in water.
In terms of color, it is mostly colorless to light yellow. This color is also one of its physical characteristics and can be visually distinguished by the naked eye.
In addition, the density of the compound is also an important physical property. The determination of its density requires precise experimental methods to determine the quality of the substance per unit volume, which is of critical significance in many chemical processes and theoretical studies.
In short, the physical properties of 1-chloro-4-ethylsulfonyl-2-nitrobenzene, such as melting point, solubility, color, density, etc., are the key basis for in-depth understanding of this compound and proper disposal in practical applications.
In this compound, the chlorine atom has high activity and is easy to participate in nucleophilic substitution reactions. Due to its electronegativity, the electron cloud density of the benzene ring can be changed, and the electron cloud density of the orthopelar position is reduced, which reduces the activity of electrophilic substitution reactions. In alkali, chlorine atoms can be replaced by nucleophilic reagents such as hydroxyl groups and amino groups to form corresponding substitution products.
Ethylsulfonyl is an electron-withdrawing group, which can enhance molecular polarity and has an electron-pulling effect on the benzene ring electron cloud, further reducing the electron cloud density of the benzene ring, affecting the reactivity and selectivity on the benzene ring. At the same time, because of its sulfur-oxygen double bond, it can participate in some redox reactions or react with nucleophiles.
Nitro is also a strong electron-withdrawing group, which greatly reduces the electron cloud density of the benzene ring and makes it more difficult for the electrophilic substitution of the benzene ring to occur. However, nitro can be reduced under specific conditions, such as under the action of metals and acids, it can be gradually reduced to amino groups, which is an important conversion step in organic synthesis.
1-chloro-4-ethylsulfonyl-2-nitrobenzene can be used as an important intermediate in the field of organic synthesis due to the characteristics of each group in its structure. Through nucleophilic substitution, reduction and other reactions, a variety of organic compounds containing different functional groups are prepared, showing unique chemical properties and reactivity.
Then, the ethanesulfonylation of chlorobenzene is carried out. In this step, ethanesulfonylation reagents, such as ethanesulfonyl chloride, are used. Under the catalysis of alkali, ethanesulfonyl groups are successfully integrated into the benzene ring to obtain 4-ethanesulfonyl chlorobenzene. The type and dosage of bases have a great impact on the reaction process and need to be carefully regulated.
Finally, nitrate 4-ethanesulfonyl chlorobenzene. Select a suitable nitrification reagent, such as a mixed acid system of concentrated nitric acid and concentrated sulfuric acid, and under strict control of the reaction temperature and other conditions, the nitro group is introduced into the benzene ring to form the target product 1-chloro-4-ethanesulfonyl-2-nitrobenzene. In this nitrification process, temperature control is crucial. If the temperature is too high, it is easy to cause side reactions to occur, which affects the purity and yield of the product.
There are other methods, using nitrobenzene as the starting material, chlorination first, and then ethanesulfonylation, which can also achieve the purpose. However, each step of the reaction requires detailed investigation of conditions and fine operation to make the synthesis process smooth and obtain satisfactory products.
First, when storing, find a cool, dry and well-ventilated place. This compound is easy to decompose when heated, and the high temperature environment may cause it to deteriorate, so it should be kept away from fire and heat sources, such as boilers and heating equipment. And because it is quite sensitive to humidity, humid environment or cause reactions such as hydrolysis, the humidity at the storage place must be strictly controlled and should be maintained at a relatively low level.
Second, the packaging must be tight. Appropriate packaging materials should be used to ensure that there is no risk of leakage. For example, use sealed glass bottles or special plastic containers to prevent them from coming into contact with air and moisture. At the same time, the name, characteristics, hazards and other key information of the compound should be clearly marked on the outside of the package for identification and handling.
Third, during transportation, relevant regulations on the transportation of hazardous chemicals must be followed. Transportation vehicles should be equipped with necessary emergency equipment and protective equipment, such as fire extinguishers, leakage emergency treatment tools, etc. Drivers and escorts must also undergo professional training, familiar with the characteristics of the compound and emergency disposal methods. During transportation, be sure to drive carefully to avoid bumps and collisions to prevent the leakage of the compound due to package damage.
Fourth, this compound is toxic and corrosive, and storage and transportation personnel must take good personal protection. Protective clothing, gloves, protective glasses, etc. should be worn to prevent contact with skin and eyes. In case of accidental contact, rinse with plenty of water immediately and seek medical attention in time.
Fifth, storage areas and transportation vehicles should also be kept away from food, medicine and other items to prevent contamination. And it needs to be stored and transported separately from oxidants, reducing agents, etc., which endanger safety due to mutual contact or severe reactions.

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