Linshang Chemical
PRODUCTS
1-Chloro-4-(Ethylsulphonyl)Benzene
Linshang Chemical
|
HS Code |
838696 |
| Chemical Formula | C8H9ClO2S |
| Molar Mass | 204.67 g/mol |
| Appearance | Solid (likely white or off - white) |
| Odor | Typically has a characteristic, possibly pungent odor |
| Solubility In Water | Low solubility in water |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
| Stability | Can be reactive, especially towards nucleophiles due to the presence of the sulfonyl chloride group |
As an accredited 1-Chloro-4-(Ethylsulphonyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 4 - (ethylsulphonyl)benzene in 500g bottles for chemical packaging. |
| Storage | 1 - Chloro - 4 - (ethylsulphonyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent leakage and exposure to air and moisture. Store it separately from incompatible substances like oxidizing agents, bases, and reactive metals to avoid potential chemical reactions. |
| Shipping | 1 - chloro - 4 - (ethylsulphonyl)benzene is shipped in tightly sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling and secure transportation to prevent spills and exposure. |
Competitive 1-Chloro-4-(Ethylsulphonyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Chloro-4-(Ethylsulphonyl)Benzene in China?
As a trusted 1-Chloro-4-(Ethylsulphonyl)Benzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Chloro-4-(Ethylsulphonyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 1-chloro-4- (ethylsulphonyl) benzene?
1-Chloro-4- (ethylsulphonyl) benzene, or 1-chloro-4- (ethylsulphonyl) benzene, is an organic compound whose chemical properties are of great interest and worth exploring.
When it comes to chemical activity, the chlorine atoms on the benzene ring show some reactivity. Because the chlorine atoms are connected to the benzene ring, they can undergo nucleophilic substitution reactions due to the electronic effect of the benzene ring. When there are nucleophiles, the nucleophiles will attack the carbon atoms attached to the chlorine atoms, and the chlorine atoms will leave with a pair of electrons to form new compounds. For example, if an aqueous solution of sodium hydroxide is used as a nucleophilic reagent, under suitable conditions, the chlorine atom will be replaced by a hydroxyl group, resulting in the formation of 1-hydroxy-4- (ethanesulfonyl) benzene.
And ethanesulfonyl group (-SO _ 2 CH _ 2) also has a profound impact on the chemical properties of the compound. The sulfonyl group has strong electron absorption, which can reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution reaction of the benzene ring. However, under certain conditions, the benzene ring can still undergo electrophilic substitution reaction, but the reaction conditions are more severe than those of benzene. For example, when nitrification occurs, more intense reaction conditions are required to successfully replace the hydrogen atom on the benzene ring with
From a redox perspective, the compound is relatively stable and is not easily oxidized by common weak oxidants. However, under the action of strong oxidants, the valence state of sulfur atoms in ethanesulfonyl groups may change, or it can be further oxidized to sulfur-containing compounds with higher valence states.
In addition, the physical properties of this compound are also related to its chemical properties. It is insoluble in water because both the benzene ring and ethanesulfonyl group in the molecule are hydrophobic groups. However, it is soluble in some organic solvents, such as dichloromethane, chloroform, etc., which is conducive to its operation and reaction in organic synthesis reaction systems.
In summary, the chemical properties of 1-chloro-4- (ethylsulfonyl) benzene are determined by its molecular structure, and can be used as an important intermediate in the field of organic synthesis, participating in many chemical reactions for the synthesis of organic compounds with specific functions.
When it comes to chemical activity, the chlorine atoms on the benzene ring show some reactivity. Because the chlorine atoms are connected to the benzene ring, they can undergo nucleophilic substitution reactions due to the electronic effect of the benzene ring. When there are nucleophiles, the nucleophiles will attack the carbon atoms attached to the chlorine atoms, and the chlorine atoms will leave with a pair of electrons to form new compounds. For example, if an aqueous solution of sodium hydroxide is used as a nucleophilic reagent, under suitable conditions, the chlorine atom will be replaced by a hydroxyl group, resulting in the formation of 1-hydroxy-4- (ethanesulfonyl) benzene.
And ethanesulfonyl group (-SO _ 2 CH _ 2) also has a profound impact on the chemical properties of the compound. The sulfonyl group has strong electron absorption, which can reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution reaction of the benzene ring. However, under certain conditions, the benzene ring can still undergo electrophilic substitution reaction, but the reaction conditions are more severe than those of benzene. For example, when nitrification occurs, more intense reaction conditions are required to successfully replace the hydrogen atom on the benzene ring with
From a redox perspective, the compound is relatively stable and is not easily oxidized by common weak oxidants. However, under the action of strong oxidants, the valence state of sulfur atoms in ethanesulfonyl groups may change, or it can be further oxidized to sulfur-containing compounds with higher valence states.
In addition, the physical properties of this compound are also related to its chemical properties. It is insoluble in water because both the benzene ring and ethanesulfonyl group in the molecule are hydrophobic groups. However, it is soluble in some organic solvents, such as dichloromethane, chloroform, etc., which is conducive to its operation and reaction in organic synthesis reaction systems.
In summary, the chemical properties of 1-chloro-4- (ethylsulfonyl) benzene are determined by its molecular structure, and can be used as an important intermediate in the field of organic synthesis, participating in many chemical reactions for the synthesis of organic compounds with specific functions.
What are the main uses of 1-chloro-4- (ethylsulphonyl) benzene?
1-Chloro-4- (ethylsulfonyl) benzene, this substance has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. Due to its unique structure, chlorine atoms and ethylsulfonyl groups give benzene rings a unique activity, which can be replaced by other functional groups through many chemical reactions, such as nucleophilic substitution reactions, and then various complex organic compounds can be constructed.
In pharmaceutical chemistry, its significance is extraordinary. In the design and synthesis of some drug molecules, 1-chloro-4- (ethylsulfonyl) benzene is often used as the starting material. With its specific structure, it helps to build a molecular framework with biological activity and lays the foundation for the creation of new drugs.
In the field of materials science, there are also many figures. Or participate in the synthesis process of polymer materials, introducing polymer structures through chemical reactions, endowing materials with unique properties such as special solubility and thermal stability, so as to meet the requirements of different application scenarios for material properties.
In addition, in the field of fine chemicals, it is used as a raw material to synthesize a variety of fine chemicals, such as special dyes, flavors and other additives, to improve product performance and quality and enhance its competitiveness in the market.
In pharmaceutical chemistry, its significance is extraordinary. In the design and synthesis of some drug molecules, 1-chloro-4- (ethylsulfonyl) benzene is often used as the starting material. With its specific structure, it helps to build a molecular framework with biological activity and lays the foundation for the creation of new drugs.
In the field of materials science, there are also many figures. Or participate in the synthesis process of polymer materials, introducing polymer structures through chemical reactions, endowing materials with unique properties such as special solubility and thermal stability, so as to meet the requirements of different application scenarios for material properties.
In addition, in the field of fine chemicals, it is used as a raw material to synthesize a variety of fine chemicals, such as special dyes, flavors and other additives, to improve product performance and quality and enhance its competitiveness in the market.
What is the synthesis method of 1-chloro-4- (ethylsulphonyl) benzene?
The synthesis method of 1-chloro-4- (ethylsulfonyl) benzene covers various paths to be found. One method can also start with p-chlorothiophenol. First, p-chlorothiophenol reacts with haloethane in an alkaline environment. This base, such as sodium hydroxide, can also be used. The two meet, and through nucleophilic substitution, p-chloroethylene sulfide is obtained.
After that, if you want to turn the sulfide into a sulfonyl group, you can use the method of oxidation. With hydrogen peroxide or m-chloroperoxybenzoic acid and other strong oxidants, the sulfur atom of the sulfide is oxidized to form 1-chloro-4- (ethylsulfonyl) benzene. During this process, you need to pay attention to the reaction conditions when oxidizing. Temperature and reagent dosage are all important to prevent excessive oxidation.
There are other methods, which can be started with p-chlorobenzenesulfonyl chloride. Make p-chlorobenzenesulfonyl chloride meet Grignard's reagents, such as ethylmagnesium bromide. The carbon-magnesium bond of ethyl in Grignard's reagent is nucleophilic, attacking the sulfur atom of sulfonyl chloride, and the chlorine leaves to obtain 1-chloro-4- (ethylsulfonyl) benzene. When Grignard's reagent is used, the reaction environment must be anhydrous, otherwise Grignard's reagent will be easily damaged and the reaction will be difficult.
Another example is to use p-chlorobenzenesulfonic acid as the starting material and first convert it into the corresponding sulfonate, such as ethyl p-chlorobenzenesulfonic acid. It can be obtained by esterification of p-chlorobenzenesulfonic acid and ethanol under the catalysis of concentrated sulfuric acid. Then, the sulfonate is treated with chlorinated reagents, such as thionyl chloride. After substitution reaction, the ethoxy group of the sulfonate is replaced by a chlorine atom, and 1-chloro-4- (ethylsulfonyl) benzene can also be obtained.
All synthesis methods have their own advantages and disadvantages, and they need to be selected according to the availability of raw materials, the difficulty of reaction, and the purity of the product.
After that, if you want to turn the sulfide into a sulfonyl group, you can use the method of oxidation. With hydrogen peroxide or m-chloroperoxybenzoic acid and other strong oxidants, the sulfur atom of the sulfide is oxidized to form 1-chloro-4- (ethylsulfonyl) benzene. During this process, you need to pay attention to the reaction conditions when oxidizing. Temperature and reagent dosage are all important to prevent excessive oxidation.
There are other methods, which can be started with p-chlorobenzenesulfonyl chloride. Make p-chlorobenzenesulfonyl chloride meet Grignard's reagents, such as ethylmagnesium bromide. The carbon-magnesium bond of ethyl in Grignard's reagent is nucleophilic, attacking the sulfur atom of sulfonyl chloride, and the chlorine leaves to obtain 1-chloro-4- (ethylsulfonyl) benzene. When Grignard's reagent is used, the reaction environment must be anhydrous, otherwise Grignard's reagent will be easily damaged and the reaction will be difficult.
Another example is to use p-chlorobenzenesulfonic acid as the starting material and first convert it into the corresponding sulfonate, such as ethyl p-chlorobenzenesulfonic acid. It can be obtained by esterification of p-chlorobenzenesulfonic acid and ethanol under the catalysis of concentrated sulfuric acid. Then, the sulfonate is treated with chlorinated reagents, such as thionyl chloride. After substitution reaction, the ethoxy group of the sulfonate is replaced by a chlorine atom, and 1-chloro-4- (ethylsulfonyl) benzene can also be obtained.
All synthesis methods have their own advantages and disadvantages, and they need to be selected according to the availability of raw materials, the difficulty of reaction, and the purity of the product.
What are the precautions for 1-chloro-4- (ethylsulphonyl) benzene in storage and transportation?
For 1-chloro-4- (ethylsulfonyl) benzene, many things should be paid attention to during storage and transportation. This is because the substance has specific chemical properties, which is related to safety and quality.
First storage conditions. It is advisable to find a cool, dry and well-ventilated place to store it. This shade can avoid chemical changes caused by high temperature, drying can prevent hydrolysis or deterioration caused by moisture, and ventilation can dissipate harmful gases that may accumulate. And it should be kept away from fire and heat sources, because the compound may be flammable, it is easy to cause combustion or even explosion in case of open flames and hot topics.
In addition, when storing, it should be stored separately from oxidants, alkalis, etc., and must not be mixed. Due to its active chemical properties, it may meet with oxidants or cause severe oxidation reactions; contact with alkalis may also trigger chemical reactions, causing the substance to fail or generate harmful products.
When transporting, caution is also required. The transport vehicle must ensure that the vehicle is in good condition and has corresponding safety facilities. The container containing this object must be firmly sealed to prevent leakage. During loading and unloading, the operator should handle it lightly, and it is strictly forbidden to drop and heavy pressure, so as not to damage the container and cause material leakage.
If there is a leak during transportation, emergency measures should be taken immediately. Evacuate the surrounding crowd and set up warning signs to prevent unrelated personnel from approaching. Emergency responders need to wear professional protective equipment to avoid direct contact with leaks. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be built or excavated for containment, and then properly disposed of.
All of these are to ensure the safety and stability of 1-chloro-4- (ethylsulfonyl) benzene during storage and transportation, and must not be negligent.
First storage conditions. It is advisable to find a cool, dry and well-ventilated place to store it. This shade can avoid chemical changes caused by high temperature, drying can prevent hydrolysis or deterioration caused by moisture, and ventilation can dissipate harmful gases that may accumulate. And it should be kept away from fire and heat sources, because the compound may be flammable, it is easy to cause combustion or even explosion in case of open flames and hot topics.
In addition, when storing, it should be stored separately from oxidants, alkalis, etc., and must not be mixed. Due to its active chemical properties, it may meet with oxidants or cause severe oxidation reactions; contact with alkalis may also trigger chemical reactions, causing the substance to fail or generate harmful products.
When transporting, caution is also required. The transport vehicle must ensure that the vehicle is in good condition and has corresponding safety facilities. The container containing this object must be firmly sealed to prevent leakage. During loading and unloading, the operator should handle it lightly, and it is strictly forbidden to drop and heavy pressure, so as not to damage the container and cause material leakage.
If there is a leak during transportation, emergency measures should be taken immediately. Evacuate the surrounding crowd and set up warning signs to prevent unrelated personnel from approaching. Emergency responders need to wear professional protective equipment to avoid direct contact with leaks. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be built or excavated for containment, and then properly disposed of.
All of these are to ensure the safety and stability of 1-chloro-4- (ethylsulfonyl) benzene during storage and transportation, and must not be negligent.
What are the effects of 1-chloro-4- (ethylsulphonyl) benzene on the environment and human health?
1-Chloro-4- (ethylsulfonyl) benzene is one of the organic compounds. This substance has certain effects on the environment and human health.
First talk about its impact on the environment. If this substance is accidentally released into the environment, it has certain chemical stability or is difficult to degrade rapidly. In soil, it may change the chemical properties of soil, affect the survival and reproduction of soil microorganisms, and then interfere with the balance of soil ecosystems. In water bodies, it may affect the water quality and be toxic to aquatic organisms. Aquatic animals such as fish and shellfish, or their physiological functions are damaged due to exposure to this substance, and their growth and reproduction are hindered. It may be enriched in organisms and passed through the food chain, posing a potential threat to higher trophic organisms.
As for the impact on human health, 1-chloro-4- (ethylsulfonyl) benzene may be irritating. If human skin comes into contact with it, it may cause redness and itching of the skin, and blister and ulceration in severe cases. If it is accidentally inhaled, its volatile gaseous substances may cause coughing, asthma, and even damage to lung tissue, affecting respiratory function. Long-term exposure to this substance, according to relevant studies, may be mutagenic, interfering with the genetic material of normal human cells, increasing the risk of cancer and other diseases. Pregnant women who are exposed to it or affect the normal development of the fetus through the placenta may be teratogenic.
In conclusion, 1-chloro-4- (ethylsulfonyl) benzene poses potential hazards to the environment and human health, and should be treated with caution during its production, use, and disposal to reduce its adverse effects on ecology and humans.
First talk about its impact on the environment. If this substance is accidentally released into the environment, it has certain chemical stability or is difficult to degrade rapidly. In soil, it may change the chemical properties of soil, affect the survival and reproduction of soil microorganisms, and then interfere with the balance of soil ecosystems. In water bodies, it may affect the water quality and be toxic to aquatic organisms. Aquatic animals such as fish and shellfish, or their physiological functions are damaged due to exposure to this substance, and their growth and reproduction are hindered. It may be enriched in organisms and passed through the food chain, posing a potential threat to higher trophic organisms.
As for the impact on human health, 1-chloro-4- (ethylsulfonyl) benzene may be irritating. If human skin comes into contact with it, it may cause redness and itching of the skin, and blister and ulceration in severe cases. If it is accidentally inhaled, its volatile gaseous substances may cause coughing, asthma, and even damage to lung tissue, affecting respiratory function. Long-term exposure to this substance, according to relevant studies, may be mutagenic, interfering with the genetic material of normal human cells, increasing the risk of cancer and other diseases. Pregnant women who are exposed to it or affect the normal development of the fetus through the placenta may be teratogenic.
In conclusion, 1-chloro-4- (ethylsulfonyl) benzene poses potential hazards to the environment and human health, and should be treated with caution during its production, use, and disposal to reduce its adverse effects on ecology and humans.
Scan to WhatsApp
