1-Chloro-4-Fluoro-2-Methoxybenzene
Linshang Chemical
HS Code |
486408 |
Chemical Formula | C7H6ClFO |
Molar Mass | 160.573 g/mol |
Appearance | Colorless to light yellow liquid |
Boiling Point | 190 - 192 °C |
Melting Point | N/A |
Density | 1.258 g/mL at 25 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
Flash Point | 71 °C |
Odor | Characteristic aromatic odor |
As an accredited 1-Chloro-4-Fluoro-2-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 - chloro - 4 - fluoro - 2 - methoxybenzene: 500g in a sealed, corrosion - resistant chemical - grade bottle. |
Storage | 1 - Chloro - 4 - fluoro - 2 - methoxybenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly - sealed container to prevent leakage and exposure to air and moisture, which could potentially cause degradation or chemical reactions. Label the storage container clearly for easy identification and safety. |
Shipping | 1 - Chloro - 4 - fluoro - 2 - methoxybenzene is shipped in accordance with chemical transportation regulations. Packed in suitable containers, it's transported by road or sea, ensuring proper handling to prevent spills and maintain safety. |
Competitive 1-Chloro-4-Fluoro-2-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1-Chloro-4-Fluoro-2-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
1. ** Uses in the field of pharmaceutical chemistry **:
Methoxybenzyl compounds often have unique chemical structures and can be used as key intermediates for the synthesis of various drugs. Due to the presence of methoxy groups, they can regulate the physical and chemical properties of drug molecules such as polarity and lipophilicity, thereby affecting the ability of drugs to bind to targets. For example, in the synthesis of some antibacterial drugs, 1-deuterium-4-tritium-2-methoxybenzyl can participate in the construction of the core skeleton, making it easier for the drug to penetrate the bacterial cell wall, enhancing antibacterial activity, and providing a powerful means for fighting bacteria and treating infectious diseases.
2. ** Applications in materials science **:
It can be used to prepare organic materials with special properties. The electronic effect of methoxy can change the photoelectric properties of materials. After 1-deuterium-4-tritium-2-methoxybenzyl participates in the synthesis of materials, the resulting materials may exhibit unique properties in light absorption, emission, etc. For example, in the preparation of organic Light Emitting Diode (OLED) materials, the luminous efficiency and stability of materials can be optimized, providing new material choices for the development of display technology, and promoting the display screen to move towards a clearer and more energy-efficient direction.
3. ** Value in organic synthetic chemistry **:
As an important building block for organic synthesis, 1-deuterium-4-tritium-2-methoxybenzyl can introduce different functional groups through various chemical reactions, such as nucleophilic substitution, addition, etc., to construct complex organic molecular structures. Chemical researchers can use this to synthesize organic compounds with unique functions, expand the research scope of organic chemistry, provide a foundation for the creation and exploration of new substances, and promote the continuous development of organic synthetic chemistry.
Its taste is very special. It has a light fragrance, but it is not as floral as it is. It is a special fragrance that can be dispersed, and people feel refreshed and refreshed. It is also a way to explain its delicacy.
As for its boiling, it can be obtained at a certain degree. The characteristics of this boiling are of paramount importance in its operation such as lifting and dividing. Due to the boiling of different compounds, it can be effectively precipitated from the mixture.
Its melting time is also fixed, and the degree of melting is reduced to a certain extent. The material is solidified by the liquid, just like solidification, and it is the same. The value of this melting time is its inherent property, which can be used as an important basis for determining this material.
Furthermore, its density is also an important physical property. Compared with water, it is more or less heavy. This property is related to the multiplication of liquid composition and the like. If its density is low in water, it will float on the water, and vice versa, it will sink under water. This difference provides more convenience for the processing and production.
In terms of solubility, this substance can be dissolved in water, easily soluble, like water and emulsion. However, in water, its solubility is different, or slightly soluble, or soluble, which is determined by factors such as its molecular solubility. This solubility property also plays an indispensable role in extraction, preparation, and other chemical operations.
To know this, it is clear that its molecular chemistry. 1 + -4 + -ene-2 + -methoxylbenzene, with alkenyl methoxy on the benzene. For alkenyl, carbon-containing carbon, this makes it incongruous, easy to add and reverse. In case of elemental, chemical, etc., it can generate addition, cracking, and external addition.
And methoxy, which supplies the daughter group, can increase the density of benzene. The anti-activity of benzene makes it easier to replace the anti-activity of benzene, and the anti-activity of methoxy groups is more active.
However, in the general environment, 1 + -4 + -ene-2 + -methoxybenzene is not a good thing. The presence of alkenyl groups makes it sensitive to oxidation, addition, etc. In case of oxidation, the alkenyl group can be oxidized, causing molecular modification. And because benzene is affected by methoxy groups, it is also more susceptible to anti-attack.
Furthermore, the anti-reaction of alkenyl groups may also affect their characterization. Different air conditions are different, and the molecular force is different, and the characterization is also poor.
Therefore, 1 + -4 + -ene-2 + -methoxybenzene is a non-determinate, and under specific conditions, it is easy to reverse and cause its change.
First take an appropriate amount of 4-pentene-2-alcohol and place it in a reaction vessel. Carefully add an appropriate amount of acetic anhydride and a catalyst amount of concentrated sulfuric acid to this vessel. Under suitable temperature conditions, stir the reaction at controlled temperature. This step aims to esterify 4-pentene-2-alcohol and acetic anhydride to obtain 2-acetoxy-4-pentene. This process requires close attention to temperature changes to prevent side reactions from occurring.
After the esterification reaction is completed, the reaction product is separated and purified to obtain pure 2-acetoxy-4-pentene. Thereafter, 2-acetoxy-4-pentene is transferred to another reaction vessel, and an appropriate amount of hydrogen bromide gas is added. Under the condition of light or the addition of an initiator, 2-acetoxy-4-pentene is added to hydrogen bromide. During this reaction, it is necessary to ensure the uniformity of the reaction system and sufficient contact of the reactants, so that the addition reaction can proceed smoothly, and then 1-bromo-4-pentyl-2-acetoxy benzene is formed.
After the addition reaction is completed, the product is separated and purified. Impurities can be removed by distillation, extraction, recrystallization, etc., to obtain pure 1-bromo-4-pentyl-2-acetoxybenzene. The whole preparation process requires strict control of the reaction conditions and careful operation to ensure the purity and yield of the product.
When storing, the first environment is dry. Due to its nature, it is susceptible to water vapor. If the environment is humid, water vapor may react with the substance, causing it to deteriorate and lose its original characteristics and effectiveness. The warehouse must have good ventilation facilities to allow smooth air circulation to prevent the accumulation of volatile gases from reaching dangerous concentrations and causing safety accidents. Temperature also needs to be strictly controlled and should be maintained in a suitable range to avoid too high or too low temperature. If the temperature is too high, it may cause the volatilization of the substance to increase and the reactivity to change; if the temperature is too low, it may cause the substance to solidify and crystallize, which will affect its subsequent use performance.
During transportation, packaging is extremely critical. Packaging materials must be solid and durable, capable of resisting routine vibration, collision and extrusion, to ensure that the substance is not damaged during transportation bumps. Close inspection of the packaging is necessary to prevent leakage. Once leaked, it will not only cause material loss, but also may pose a threat to the transportation environment and personnel safety. Transportation tools need to be clean and pollution-free to avoid other impurities from being mixed into the substance, which will affect its purity and quality. Transportation personnel must also undergo professional training, familiar with the characteristics of the substance and emergency treatment methods. In case of unexpected situations, they can respond quickly and correctly to minimize

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