1-Chloro-4-Methoxy-2-Nitrobenzene
Linshang Chemical
HS Code |
379033 |
Chemical Formula | C7H6ClNO3 |
Molar Mass | 187.58 g/mol |
Appearance | Yellow solid |
Melting Point | 69 - 71 °C |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, acetone |
Odor | Characteristic odor |
Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 1-Chloro-4-Methoxy-2-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 100g of 1 - chloro - 4 - methoxy - 2 - nitrobenzene packaged in a sealed plastic bottle. |
Storage | 1 - Chloro - 4 - methoxy - 2 - nitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials. This helps prevent decomposition, potential chemical reactions, and release of harmful vapors. |
Shipping | 1 - Chloro - 4 - methoxy - 2 - nitrobenzene is shipped in sealed, corrosion - resistant containers. Special handling per hazardous chemical regulations is required. Shipment should be in well - ventilated vehicles to prevent risks. |
Competitive 1-Chloro-4-Methoxy-2-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1-Chloro-4-Methoxy-2-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of medicine, it can be used as an intermediate for drug synthesis. The molecular structure of the Gain contains specific functional groups, which can be converted into drug molecules with specific pharmacological activities through a series of reactions by means of chemical synthesis. For example, other active groups can be introduced by modifying its structure to prepare drugs with antibacterial, anti-inflammatory or anti-tumor effects, which can help fight various diseases and contribute to human health.
In the field of fragrances, this compound can be used to prepare various flavors due to its unique chemical structure or special aroma. Whether it is a daily flavor, such as perfume, air freshener, etc., which imparts a pleasant aroma to the product; or a edible flavor, which adds a unique flavor to the food, it can play an important role in enhancing the olfactory experience of the product with its unique smell.
In the field of pesticides, it can be properly modified and transformed into pesticide products with insecticidal, bactericidal or weeding properties. With its chemical properties, it can inhibit or kill specific pests, bacteria or weeds, assist agricultural production, improve crop yield and quality, and ensure food security.
In conclusion, 1 + -alkane-4-methoxy-2-acetylbenzene, with its unique chemical structure, has shown important application value in many fields such as medicine, flavors and pesticides, and is of great significance for promoting the development of related industries.
Looking at its properties, under room temperature and pressure, it is mostly liquid and has a certain fluidity. Its color may be almost colorless or slightly yellowish, and the color varies slightly depending on the purity.
When it comes to boiling points, there are various functional groups in its molecular structure that interact with each other, causing its boiling point to be in a specific range. The presence of methoxy and acetyl groups enhances the intermolecular force, causing the boiling point to increase, generally boiling at a relatively high temperature. The specific value depends on the accurate measurement, but the boiling point is significantly higher than that of ordinary simple alkanes.
In terms of melting point, due to the regularity of molecular structure and the influence of functional groups, the intermolecular arrangement is specific, giving it a certain melting point. When the temperature drops below the melting point, it changes from liquid to solid.
Solubility is also an important physical property. The compound has good solubility in organic solvents, such as common organic solvents such as ethanol and ether. Due to the principle of "similar miscibility", its molecular structure is similar to that of organic solvents, and it can be mixed and dissolved with each other. However, the solubility in water is not good, because the overall polarity of the molecule is not extremely strong, and the interaction with water molecules is weak, it is difficult to dissolve in water.
In addition, density is also one of the characteristics. Compared with common organic solvents or water, the relative density has its unique value, which has an important impact on its distribution and mixing in different media in practical applications. Its density can help researchers understand the location of the substance in the system and delamination with other substances.
The above physical properties lay the foundation for its application in chemical, pharmaceutical and other fields. According to these properties, researchers can perform separation, purification, synthesis and other operations to achieve the desired goal.
In this compound, the alkane part has a certain saturation, the carbon-carbon single bond is relatively stable, and the addition reaction is not easy to occur. Methoxy group, as the power supply group, can affect the electron cloud density of the benzene ring through induction effect and conjugation effect, so that the electron cloud density of the benzene ring is relatively increased. In the electrophilic substitution reaction, methoxy group makes the benzene ring more likely to react in the ortho and para-sites, and also contributes to the stability of the whole compound. The acetyl group is connected to the benzene ring. Although there is an electron-withdrawing conjugation effect, the stability of the overall structure has not been greatly weakened due to the steric resistance and the power supply action of the methoxy group.
In the general chemical environment, if there are no special conditions such as strong oxidants, strong acids, and strong bases, the compound can maintain its own structure. For example, at room temperature and pressure without the action of specific chemical reagents, it will not spontaneously decompose or rearrange its structure. However, under specific chemical reaction conditions, such as in the presence of suitable catalysts, substitution reactions may occur on the benzene ring; reactions such as nucleophilic addition may occur on the carbonyl group. However, these reactions require specific reaction conditions to trigger, and do not occur easily in ordinary environments. Therefore, within the conventional conditions, 1 + -alkane-4-methoxy-2-acetylbenzene has good chemical stability.
First, naphthalene is used as the starting material. First, the naphthalene is reacted with a methoxylating agent under specific conditions to introduce a methoxy group. In this step, a suitable catalyst and reaction temperature are selected to precisely connect the methoxy group to the fourth position of the naphthalene ring. Then, the generated 4-methoxy naphthalene is reacted with an acetylating agent under the action of an appropriate catalyst such as anhydrous aluminum trichloride, and an acetyl group is introduced into the 2-position naphthalene ring to obtain 2-acetyl-4-methoxy naphthalene. Finally, the 2-acetyl-4-methoxy naphthalene is reacted with a brominating agent, such as bromine, in the presence of an appropriate solvent and catalyst, so that the bromine atom replaces the hydrogen atom in the 1-position to obtain 1-bromo-4-methoxy-2-acetylnaphthalene.
Second, the naphthalene can be acetylated first, the acetyl group is introduced at the second position of the naphthalene ring, and then the methoxylation reaction is carried out, and the methoxy group is introduced at the fourth position. After that, as in the previous method, the brominating reagent is reacted with it, so that the bromine atom occupies one position to obtain the target product.
When operating, all reaction steps need to pay attention to the precise control of the reaction conditions. If the temperature is too high or too low, it can cause changes in the selectivity of the reaction or increase the side reactions. The purity of the reagent used is also crucial, and impurities may affect the reaction process and product purity. And after each step of the reaction, suitable separation and purification methods, such as column chromatography, recrystallization, etc., are required to ensure the purity of the intermediate and final products before 1-bromo-4-methoxy-2-acetylnaphthalene can be successfully prepared.
Temperature is also a key factor. Do not leave it in a high temperature environment to prevent chemical reactions from triggering decomposition or other adverse changes. Under high temperatures, molecular activity will increase, or structural changes will be caused, which will damage the original characteristics.
When storing, keep away from fire sources and oxidants. This compound may be flammable and dangerous in case of fire; in contact with oxidants, it is easy to trigger a violent reaction and cause accidents.
During transportation, the packaging must be tight. Select appropriate packaging materials to ensure that it can resist vibration, collision and leakage. If the packaging is not good, the container will be damaged during transportation, and the compound will leak, which will not only be wasted, but also endanger the environment and personnel safety.
At the same time, transporters need to be familiar with the characteristics of this compound and emergency treatment methods. In the event of an accident, such as leakage or fire, they can respond quickly and properly to reduce the harm.
In addition, the relevant transportation documents and labels should be complete and clear. Indicate the name, characteristics, hazards and other information of the compound so that all parties can know and prepare for protection and response in advance. Only in this way can the safety and stability of 1 + -alkane-4-methoxy-2-carbonylbenzyl be ensured during storage and transportation.

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