Linshang Chemical
PRODUCTS
1-Chloro-4-Tert-Butoxybenzene
Linshang Chemical
|
HS Code |
207208 |
| Chemical Formula | C10H13ClO |
| Molar Mass | 184.66 g/mol |
| Appearance | Typically a colorless to light - colored liquid |
| Boiling Point | Approximately 220 - 225 °C (estimated based on similar compounds) |
| Density | Around 1.04 - 1.06 g/cm³ (estimated for aromatic chloro - ethers) |
| Solubility In Water | Poorly soluble in water |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether, and chloroform |
| Flash Point | Relatively high, potentially around 90 - 100 °C (estimated) |
| Odor | May have a characteristic aromatic odor |
As an accredited 1-Chloro-4-Tert-Butoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 4 - tert - butoxybenzene in 500g bottles, well - sealed for protection. |
| Storage | 1 - Chloro - 4 - tert - butoxybenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, acids, and bases to avoid potential chemical reactions. Ensure storage areas comply with safety regulations for handling organic chemicals. |
| Shipping | 1 - Chloro - 4 - tert - butoxybenzene should be shipped in tightly sealed, corrosion - resistant containers. It must comply with regulations for hazardous chemicals, ensuring proper labeling and secure packaging to prevent spills during transit. |
Competitive 1-Chloro-4-Tert-Butoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Chloro-4-Tert-Butoxybenzene in China?
As a trusted 1-Chloro-4-Tert-Butoxybenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Chloro-4-Tert-Butoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-chloro-4-tert-butoxybenzene?
1-Chloro-4-tert-butoxy benzene is also an organic compound. It has a wide range of main uses and is often used as a key intermediate in the field of organic synthesis.
In the field of pharmaceutical chemistry, this compound can be used to create a variety of drugs. Due to its structural properties, it can participate in a series of reactions, helping to build a molecular framework with specific physiological activities, and then paving the way for the development of new drugs. For example, it may be possible to synthesize anti-cancer drugs and antibacterial agents with specific targeting through its reaction with other reagents, for human health and well-being.
In the field of materials science, 1-chloro-4-tert-butoxy benzene also has important uses. Or it can be used to prepare polymer materials with special properties. By participating in the polymerization reaction, it can impart different characteristics to the material, such as improving the heat resistance and mechanical properties of the material. This is of great significance to the research and development and production of high-end materials, such as high-performance materials used in aerospace and electronic equipment.
Furthermore, it is also indispensable in the manufacture of fine chemical products. It can be used to prepare special fragrances, dyes, etc. Because of its unique chemical structure, it can give fragrances and dyes unique color, smell and stability, and improve the quality and market competitiveness of products.
In conclusion, 1-chloro-4-tert-butoxybenzene plays an important role in many fields such as organic synthesis, medicine, materials, and fine chemicals, and has contributed to the promotion of technological progress and industrial development in various fields.
In the field of pharmaceutical chemistry, this compound can be used to create a variety of drugs. Due to its structural properties, it can participate in a series of reactions, helping to build a molecular framework with specific physiological activities, and then paving the way for the development of new drugs. For example, it may be possible to synthesize anti-cancer drugs and antibacterial agents with specific targeting through its reaction with other reagents, for human health and well-being.
In the field of materials science, 1-chloro-4-tert-butoxy benzene also has important uses. Or it can be used to prepare polymer materials with special properties. By participating in the polymerization reaction, it can impart different characteristics to the material, such as improving the heat resistance and mechanical properties of the material. This is of great significance to the research and development and production of high-end materials, such as high-performance materials used in aerospace and electronic equipment.
Furthermore, it is also indispensable in the manufacture of fine chemical products. It can be used to prepare special fragrances, dyes, etc. Because of its unique chemical structure, it can give fragrances and dyes unique color, smell and stability, and improve the quality and market competitiveness of products.
In conclusion, 1-chloro-4-tert-butoxybenzene plays an important role in many fields such as organic synthesis, medicine, materials, and fine chemicals, and has contributed to the promotion of technological progress and industrial development in various fields.
What are the physical properties of 1-chloro-4-tert-butoxybenzene?
1-Chloro-4-tert-butoxybenzene is an organic compound. Its physical properties are crucial for the performance of this compound in various chemical processes and practical applications.
First appearance, under room temperature and pressure, it often appears as a colorless to light yellow liquid, clear and with specific fluidity. It exists stably in the liquid state under standard conditions. This appearance characteristic is conducive to its operation and application in various systems.
Second, the boiling point of this compound is about 235-237 ° C. The higher boiling point indicates that the intermolecular force is strong, and a higher temperature is required to make the molecule break free from the liquid phase and transform into the gas phase. This property is of great significance when separating or purifying the compound by distillation. It can be separated from other substances with large differences in boiling points by appropriate temperature control.
Besides the melting point, the melting point is about -22 ° C, and the melting point is relatively low, which means that the temperature rises slightly, and the compound melts from solid to liquid. In some reactions or processes that require low temperature operation, attention should be paid to its low melting point characteristics to avoid changes in the state due to temperature fluctuations affecting the reaction process.
When it comes to density, its density is about 1.04 g/cm ³, which is slightly heavier than water. When it comes to liquid-liquid stratification or mixing operations, it can be effectively separated or formulated according to the density difference between it and water.
In terms of solubility, 1-chloro-4-tert-butoxybenzene is insoluble in water, because water is a polar solvent, and the molecular polarity of this compound is weak, following the principle of "similar miscibility", so the solubility in water is low. However, it is soluble in common organic solvents, such as ethanol, ether, acetone, etc. This property makes it able to participate in various reactions in suitable organic solvents in organic synthesis, achieve uniform mixing with other organic reagents, and promote efficient reaction.
1-chloro-4-tert-butoxybenzene's physical properties, such as appearance, boiling point, melting point, density and solubility, play a key role in chemical research, industrial production and related application fields, providing an important basis for the rational use of this compound.
First appearance, under room temperature and pressure, it often appears as a colorless to light yellow liquid, clear and with specific fluidity. It exists stably in the liquid state under standard conditions. This appearance characteristic is conducive to its operation and application in various systems.
Second, the boiling point of this compound is about 235-237 ° C. The higher boiling point indicates that the intermolecular force is strong, and a higher temperature is required to make the molecule break free from the liquid phase and transform into the gas phase. This property is of great significance when separating or purifying the compound by distillation. It can be separated from other substances with large differences in boiling points by appropriate temperature control.
Besides the melting point, the melting point is about -22 ° C, and the melting point is relatively low, which means that the temperature rises slightly, and the compound melts from solid to liquid. In some reactions or processes that require low temperature operation, attention should be paid to its low melting point characteristics to avoid changes in the state due to temperature fluctuations affecting the reaction process.
When it comes to density, its density is about 1.04 g/cm ³, which is slightly heavier than water. When it comes to liquid-liquid stratification or mixing operations, it can be effectively separated or formulated according to the density difference between it and water.
In terms of solubility, 1-chloro-4-tert-butoxybenzene is insoluble in water, because water is a polar solvent, and the molecular polarity of this compound is weak, following the principle of "similar miscibility", so the solubility in water is low. However, it is soluble in common organic solvents, such as ethanol, ether, acetone, etc. This property makes it able to participate in various reactions in suitable organic solvents in organic synthesis, achieve uniform mixing with other organic reagents, and promote efficient reaction.
1-chloro-4-tert-butoxybenzene's physical properties, such as appearance, boiling point, melting point, density and solubility, play a key role in chemical research, industrial production and related application fields, providing an important basis for the rational use of this compound.
What is the chemistry of 1-chloro-4-tert-butoxybenzene?
1-chloro-4-tert-butoxybenzene, that is, 1-chloro-4-tert-butoxybenzene, has the following chemical properties:
This compound contains a chlorine atom and a tert-butoxy group, and the chlorine atom is connected to the benzene ring. Due to the high electron cloud density of the benzene ring, the activity of the chlorine atom is limited. However, in the nucleophilic substitution reaction, if the conditions are suitable, the chlorine atom can be replaced by a nucleophilic reagent. In case of strong nucleophilic reagents, such as phenols, alkoxides, etc., at appropriate temperatures and solvents, the chlorine atom can be replaced by a nucleophilic group to form a new substituted benzene derivative.
Tert However, under strong acidic conditions, oxygen atoms will protonate, weakening the carbon-oxygen bond, and a hydrolysis reaction may occur. The tert-butoxy group leaves to form p-chlorophenol and tert-butanol.
In terms of oxidation reaction, because there is no easily oxidized side chain (except tert-butyl) on the benzene ring, it is relatively stable to common oxidants under general conditions. However, under certain strong oxidation conditions, such as hot concentrated sulfuric acid and potassium dichromate mixed system, the benzene ring may be oxidized to open the ring.
In the reduction reaction, if metal catalysts (such as palladium, platinum, etc.) and hydrogen are used, the benzene ring may be partially or completely hydrogenated to form the corresponding cyclohexane derivative. If metal hydrides (such as lithium aluminum hydride) are used, they generally have no effect on ether bonds, mainly because chlorine atoms may be reduced to hydrogen to form 4-tert-butoxy benzene.
In terms of solubility, due to the hydrophobic benzene ring and tert-butyl group, they have little solubility in water, but they have better solubility in common organic solvents such as ethanol, ether, dichloromethane, etc., which provides a good dissolution environment for them to participate in organic reactions.
This compound contains a chlorine atom and a tert-butoxy group, and the chlorine atom is connected to the benzene ring. Due to the high electron cloud density of the benzene ring, the activity of the chlorine atom is limited. However, in the nucleophilic substitution reaction, if the conditions are suitable, the chlorine atom can be replaced by a nucleophilic reagent. In case of strong nucleophilic reagents, such as phenols, alkoxides, etc., at appropriate temperatures and solvents, the chlorine atom can be replaced by a nucleophilic group to form a new substituted benzene derivative.
Tert However, under strong acidic conditions, oxygen atoms will protonate, weakening the carbon-oxygen bond, and a hydrolysis reaction may occur. The tert-butoxy group leaves to form p-chlorophenol and tert-butanol.
In terms of oxidation reaction, because there is no easily oxidized side chain (except tert-butyl) on the benzene ring, it is relatively stable to common oxidants under general conditions. However, under certain strong oxidation conditions, such as hot concentrated sulfuric acid and potassium dichromate mixed system, the benzene ring may be oxidized to open the ring.
In the reduction reaction, if metal catalysts (such as palladium, platinum, etc.) and hydrogen are used, the benzene ring may be partially or completely hydrogenated to form the corresponding cyclohexane derivative. If metal hydrides (such as lithium aluminum hydride) are used, they generally have no effect on ether bonds, mainly because chlorine atoms may be reduced to hydrogen to form 4-tert-butoxy benzene.
In terms of solubility, due to the hydrophobic benzene ring and tert-butyl group, they have little solubility in water, but they have better solubility in common organic solvents such as ethanol, ether, dichloromethane, etc., which provides a good dissolution environment for them to participate in organic reactions.
What are 1-chloro-4-tert-butoxybenzene synthesis methods?
1-chloro-4-tert-butoxybenzene is 1-chloro-4-tert-butoxybenzene. The synthesis method is as follows:
can be prepared by reacting p-chlorophenol with t-butanol under appropriate conditions. P-chlorophenol is used as the starting material, and tert-butanol is the reagent to provide the tert-butoxy group. First, a suitable catalyst, such as some acidic catalysts, needs to be selected. In the reaction system, the phenolic hydroxyl group of p-chlorophenol has a certain activity. Under the action of the catalyst, the hydroxyl group of t-butanol can undergo a certain degree of protonation to enhance its ability to leave. Subsequently, the tert-butyl moiety in tert-butyl alcohol undergoes a nucleophilic attack on the oxygen atom of phenol hydroxyl group, forming a carbon-oxygen bond, thereby generating 1-chloro-4-tert-butoxy benzene. During the reaction process, attention should be paid to controlling the reaction temperature and reaction time. If the temperature is too high, it may lead to side reactions, which affect the purity and yield of the product; if the temperature is too low, the reaction rate will be slow.
Another common method is to use p-chlorophenol to react with tert-butyl halide. Under basic conditions, p-chlorophenol will be converted into phenol salt negative ions, enhancing its nucleophilicity. In tert-butyl halide, the halogen atom has a certain positive electricity due to the difference in electronegativity, which makes the α-carbon atom vulnerable to the nucleophilic attack of phenol anions, and the halogen atom leaves, thereby generating the target product 1-chloro-4-tert-butoxylbenzene. In this method, the type and dosage of base are crucial. Too little dosage may lead to insufficient generation of phenol anions and incomplete reaction; too much dosage may lead to other side reactions. At the same time, the choice of tert-butyl halide also affects the reaction. Different halogen atoms have different ability to leave, which will make the reaction activity different.
In addition, it can also be synthesized by the conversion of p-chloroanis First, the appropriate functional group conversion of p-chloroanisole is carried out, and under specific conditions, the methoxy group is converted to tert-butoxy to obtain 1-chloro-4-tert-butoxy benzene. This process requires precise control of the reaction conditions and involves a series of complex organic reaction steps. The connection between each step and the optimization of conditions are the key to ensure that the target product with higher purity and yield can be obtained in the end.
can be prepared by reacting p-chlorophenol with t-butanol under appropriate conditions. P-chlorophenol is used as the starting material, and tert-butanol is the reagent to provide the tert-butoxy group. First, a suitable catalyst, such as some acidic catalysts, needs to be selected. In the reaction system, the phenolic hydroxyl group of p-chlorophenol has a certain activity. Under the action of the catalyst, the hydroxyl group of t-butanol can undergo a certain degree of protonation to enhance its ability to leave. Subsequently, the tert-butyl moiety in tert-butyl alcohol undergoes a nucleophilic attack on the oxygen atom of phenol hydroxyl group, forming a carbon-oxygen bond, thereby generating 1-chloro-4-tert-butoxy benzene. During the reaction process, attention should be paid to controlling the reaction temperature and reaction time. If the temperature is too high, it may lead to side reactions, which affect the purity and yield of the product; if the temperature is too low, the reaction rate will be slow.
Another common method is to use p-chlorophenol to react with tert-butyl halide. Under basic conditions, p-chlorophenol will be converted into phenol salt negative ions, enhancing its nucleophilicity. In tert-butyl halide, the halogen atom has a certain positive electricity due to the difference in electronegativity, which makes the α-carbon atom vulnerable to the nucleophilic attack of phenol anions, and the halogen atom leaves, thereby generating the target product 1-chloro-4-tert-butoxylbenzene. In this method, the type and dosage of base are crucial. Too little dosage may lead to insufficient generation of phenol anions and incomplete reaction; too much dosage may lead to other side reactions. At the same time, the choice of tert-butyl halide also affects the reaction. Different halogen atoms have different ability to leave, which will make the reaction activity different.
In addition, it can also be synthesized by the conversion of p-chloroanis First, the appropriate functional group conversion of p-chloroanisole is carried out, and under specific conditions, the methoxy group is converted to tert-butoxy to obtain 1-chloro-4-tert-butoxy benzene. This process requires precise control of the reaction conditions and involves a series of complex organic reaction steps. The connection between each step and the optimization of conditions are the key to ensure that the target product with higher purity and yield can be obtained in the end.
1-chloro-4-tert-butoxybenzene need to pay attention to when storing and transporting
1-Chloro-4-tert-butoxy benzene is also an organic compound. When storing and transporting it, many matters need to be paid attention to.
First storage, this compound should be stored in a cool and ventilated warehouse. Because the temperature is too high or it causes chemical reactions, causing deterioration, or even posing a safety hazard. Well ventilated can avoid the accumulation of its vapor and reduce the risk of explosion and poisoning. The relative humidity of the warehouse should also be controlled, not too high, to prevent it from being hydrolyzed by moisture, destroying the molecular structure and affecting its quality.
Furthermore, the storage place should be kept away from fire and heat sources. 1-Chloro-4-tert-butoxy benzene may be flammable. It is easy to burn and explode in case of open flames and hot topics, endangering life and property safety. At the same time, it needs to be stored separately from oxidants, acids, alkalis, etc., and cannot be mixed. It comes into contact with such substances, or a violent chemical reaction occurs, or harmful gases are produced, causing serious consequences.
As for transportation, it is necessary to ensure that the packaging is complete and stowed before transportation. The packaging should be able to effectively prevent its leakage and volatilization, and have certain pressure and shock resistance properties to avoid package damage during transportation. During transportation, the relevant regulations must be strictly followed, and the corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment should be equipped. Escort personnel also need to be familiar with its nature and emergency handling methods, and pay close attention to the condition of the goods on the way. Transport vehicles should follow the specified route and do not stop in densely populated areas and open flames to prevent major hazards in the event of accidents.
In this way, when storing and transporting 1-chloro-4-tert-butoxy benzene, strictly observe the above precautions to ensure safety and avoid accidents.
First storage, this compound should be stored in a cool and ventilated warehouse. Because the temperature is too high or it causes chemical reactions, causing deterioration, or even posing a safety hazard. Well ventilated can avoid the accumulation of its vapor and reduce the risk of explosion and poisoning. The relative humidity of the warehouse should also be controlled, not too high, to prevent it from being hydrolyzed by moisture, destroying the molecular structure and affecting its quality.
Furthermore, the storage place should be kept away from fire and heat sources. 1-Chloro-4-tert-butoxy benzene may be flammable. It is easy to burn and explode in case of open flames and hot topics, endangering life and property safety. At the same time, it needs to be stored separately from oxidants, acids, alkalis, etc., and cannot be mixed. It comes into contact with such substances, or a violent chemical reaction occurs, or harmful gases are produced, causing serious consequences.
As for transportation, it is necessary to ensure that the packaging is complete and stowed before transportation. The packaging should be able to effectively prevent its leakage and volatilization, and have certain pressure and shock resistance properties to avoid package damage during transportation. During transportation, the relevant regulations must be strictly followed, and the corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment should be equipped. Escort personnel also need to be familiar with its nature and emergency handling methods, and pay close attention to the condition of the goods on the way. Transport vehicles should follow the specified route and do not stop in densely populated areas and open flames to prevent major hazards in the event of accidents.
In this way, when storing and transporting 1-chloro-4-tert-butoxy benzene, strictly observe the above precautions to ensure safety and avoid accidents.
Scan to WhatsApp
