Linshang Chemical
PRODUCTS
1-Chloro-4-Vinylbenzene
Linshang Chemical
|
HS Code |
231200 |
| Chemical Formula | C8H7Cl |
| Molar Mass | 138.594 g/mol |
| Appearance | Colorless to light - yellow liquid |
| Boiling Point | 195 - 197 °C |
| Melting Point | -22 °C |
| Density | 1.074 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in most organic solvents |
| Flash Point | 71 °C |
| Odor | Pungent, aromatic odor |
| Vapor Pressure | 0.17 mmHg at 20 °C |
As an accredited 1-Chloro-4-Vinylbenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 4 - vinylbenzene in 500 - mL glass bottles, tightly sealed. |
| Storage | 1 - Chloro - 4 - vinylbenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly closed container, preferably made of corrosion - resistant materials. Store it separately from oxidizing agents and reactive chemicals. Avoid prolonged exposure to sunlight as it may cause decomposition. Regularly check storage conditions for safety. |
| Shipping | 1 - chloro - 4 - vinylbenzene is shipped in tightly sealed, corrosion - resistant containers. It's handled as a hazardous chemical, following strict regulations, ensuring proper ventilation and secure packaging during transport to prevent leaks and risks. |
Competitive 1-Chloro-4-Vinylbenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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What are the main uses of 1-chloro-4-vinylbenzene?
1-Chloro-4-vinylbenzene, also known as p-chlorobenzene, is an important raw material in the field of organic compounds and has critical uses in many industrial and scientific fields.
First, this compound contributes significantly to the synthesis of polymers. Through polymerization, 1-chloro-4-vinylbenzene can form unique polymer materials. For example, polymers with good thermal stability, mechanical properties and chemical stability can be prepared. Such polymers are often used in the manufacture of engineering plastics, used in automotive parts, electronic equipment casings and other fields. With their excellent properties, they can enhance the durability and reliability of products.
Second, in the field of coating industry, 1-chloro-4-vinylbenzene also plays an important role. Introducing it into coating formulations can effectively improve the hardness, wear resistance and corrosion resistance of coatings. The resulting coatings are widely used in construction, furniture and other industries, which can provide high-quality protection for the surface of objects, prolong their service life, and give objects a beautiful surface effect.
Third, in the field of pharmaceutical intermediates synthesis, 1-chloro-4-vinylbenzene also shows unique value. Because its molecular structure contains chlorine atoms and vinyl groups, it can be modified and converted through a series of chemical reactions to synthesize compounds with specific pharmacological activities. After further reaction and optimization, these pharmaceutical intermediates are expected to be developed into new drugs, which will help human health.
In addition, in the field of fragrance synthesis, 1-chloro-4-vinylbenzene can be used as a starting material to construct compounds with special aromas through specific reaction paths. These fragrance compounds are widely used in perfumes, cosmetics, food additives and other industries to add unique aroma to products, enhance product quality and market competitiveness.
In summary, 1-chloro-4-vinylbenzene, with its unique molecular structure, plays an indispensable role in the synthesis of polymers, the coating industry, the synthesis of pharmaceutical intermediates, and the synthesis of fragrances. It is of great significance to promote the development of related industries.
First, this compound contributes significantly to the synthesis of polymers. Through polymerization, 1-chloro-4-vinylbenzene can form unique polymer materials. For example, polymers with good thermal stability, mechanical properties and chemical stability can be prepared. Such polymers are often used in the manufacture of engineering plastics, used in automotive parts, electronic equipment casings and other fields. With their excellent properties, they can enhance the durability and reliability of products.
Second, in the field of coating industry, 1-chloro-4-vinylbenzene also plays an important role. Introducing it into coating formulations can effectively improve the hardness, wear resistance and corrosion resistance of coatings. The resulting coatings are widely used in construction, furniture and other industries, which can provide high-quality protection for the surface of objects, prolong their service life, and give objects a beautiful surface effect.
Third, in the field of pharmaceutical intermediates synthesis, 1-chloro-4-vinylbenzene also shows unique value. Because its molecular structure contains chlorine atoms and vinyl groups, it can be modified and converted through a series of chemical reactions to synthesize compounds with specific pharmacological activities. After further reaction and optimization, these pharmaceutical intermediates are expected to be developed into new drugs, which will help human health.
In addition, in the field of fragrance synthesis, 1-chloro-4-vinylbenzene can be used as a starting material to construct compounds with special aromas through specific reaction paths. These fragrance compounds are widely used in perfumes, cosmetics, food additives and other industries to add unique aroma to products, enhance product quality and market competitiveness.
In summary, 1-chloro-4-vinylbenzene, with its unique molecular structure, plays an indispensable role in the synthesis of polymers, the coating industry, the synthesis of pharmaceutical intermediates, and the synthesis of fragrances. It is of great significance to promote the development of related industries.
What are the physical properties of 1-chloro-4-vinylbenzene?
1-Chloro-4-vinylbenzene, its physical state is mostly liquid at room temperature. Looking at its properties, it is colorless to light yellow and has a special aromatic smell. This smell is similar to the smell of common benzene series, or irritating, and touches the sense of smell.
When it comes to the melting point, the melting point is about -15 ° C, and the boiling point is 197-200 ° C. In this way, the melting point is easy to maintain a liquid state in the daily environment. It is not easy to gasify in case of temperature. However, in certain high temperature scenarios, it can also be converted to a gaseous state.
Its density is slightly higher than that of water, about 1.07g/cm ³. If it is juxtaposed with water, it will settle under water. In terms of solubility, it is difficult to dissolve in water, but it can be miscible with common organic solvents, such as ethanol, ether, acetone, etc., in any ratio. This is because of its molecular structure and the force between the organic solvent molecules. The two are compatible and fused.
1-chloro-4-vinylbenzene is flammable, and it is easy to burn when it encounters an open flame or hot topic. When burned in air, the flame is bright and accompanied by black smoke rising. Due to the high carbon content, it does not burn. Due to its chemical structure containing chlorine atoms and vinyl groups, it has certain chemical activity and can participate in a variety of chemical reactions, such as addition and substitution. It is widely used in the field of organic synthesis and can be used as a raw material for the preparation of many polymer materials and fine chemicals.
When it comes to the melting point, the melting point is about -15 ° C, and the boiling point is 197-200 ° C. In this way, the melting point is easy to maintain a liquid state in the daily environment. It is not easy to gasify in case of temperature. However, in certain high temperature scenarios, it can also be converted to a gaseous state.
Its density is slightly higher than that of water, about 1.07g/cm ³. If it is juxtaposed with water, it will settle under water. In terms of solubility, it is difficult to dissolve in water, but it can be miscible with common organic solvents, such as ethanol, ether, acetone, etc., in any ratio. This is because of its molecular structure and the force between the organic solvent molecules. The two are compatible and fused.
1-chloro-4-vinylbenzene is flammable, and it is easy to burn when it encounters an open flame or hot topic. When burned in air, the flame is bright and accompanied by black smoke rising. Due to the high carbon content, it does not burn. Due to its chemical structure containing chlorine atoms and vinyl groups, it has certain chemical activity and can participate in a variety of chemical reactions, such as addition and substitution. It is widely used in the field of organic synthesis and can be used as a raw material for the preparation of many polymer materials and fine chemicals.
What is the chemistry of 1-chloro-4-vinylbenzene?
1 - chloro - 4 - vinylbenzene is p-chlorobenzene, which has unique chemical properties. This material has dual characteristics of olefins and halogenated aromatics.
In terms of olefin properties, carbon-containing double bonds have high reactivity. Addition reactions can occur, such as encountering bromine water, breaking the π bond in the double bond, and adding bromine atoms to the carbon atoms at both ends of the double bond, causing bromine water to fade. This is a common method to verify the existence of its double bond. Addition reactions can also be carried out. Under the action of the initiator, the double bond is opened, and many p-chlorobenzene molecules are connected to each other to form a polymer. This property is of great significance in the field of synthetic plastics, rubber and other materials.
From the perspective of halogenated aromatics, chlorine atoms are affected by benzene rings and have unique reactivity. Nucleophilic substitution reactions can occur. When co-heated with aqueous sodium hydroxide solutions, hydroxyl groups will replace chlorine atoms to form p-vinylphenol. When co-heated with alcohol solutions and strong bases, elimination reactions occur, and chlorine atoms are removed from ortho-hydrogen atoms to form intermediates containing phenyne structures, which are then converted into other products.
In addition, due to the existence of the benzene ring conjugated system, p-chlorobenzene has certain stability, and the benzene ring can undergo electrophilic substitution reaction. Although the chlorine atom is an ortho-para localization group, the reaction mainly occurs in its ortho-site and para-site, but the vinyl group also affects the reaction localization. The actual reaction needs to comprehensively consider the electronic effect and spatial effect of the two. In short, 1-chloro-4-vinylbenzene is widely used in the fields of organic synthesis and material preparation due to its special structure.
In terms of olefin properties, carbon-containing double bonds have high reactivity. Addition reactions can occur, such as encountering bromine water, breaking the π bond in the double bond, and adding bromine atoms to the carbon atoms at both ends of the double bond, causing bromine water to fade. This is a common method to verify the existence of its double bond. Addition reactions can also be carried out. Under the action of the initiator, the double bond is opened, and many p-chlorobenzene molecules are connected to each other to form a polymer. This property is of great significance in the field of synthetic plastics, rubber and other materials.
From the perspective of halogenated aromatics, chlorine atoms are affected by benzene rings and have unique reactivity. Nucleophilic substitution reactions can occur. When co-heated with aqueous sodium hydroxide solutions, hydroxyl groups will replace chlorine atoms to form p-vinylphenol. When co-heated with alcohol solutions and strong bases, elimination reactions occur, and chlorine atoms are removed from ortho-hydrogen atoms to form intermediates containing phenyne structures, which are then converted into other products.
In addition, due to the existence of the benzene ring conjugated system, p-chlorobenzene has certain stability, and the benzene ring can undergo electrophilic substitution reaction. Although the chlorine atom is an ortho-para localization group, the reaction mainly occurs in its ortho-site and para-site, but the vinyl group also affects the reaction localization. The actual reaction needs to comprehensively consider the electronic effect and spatial effect of the two. In short, 1-chloro-4-vinylbenzene is widely used in the fields of organic synthesis and material preparation due to its special structure.
What are the precautions 1-chloro-4-vinylbenzene in the production process?
1-Chloro-4-vinylbenzene is a key raw material in organic synthesis. In the industrial production process, many matters need careful attention.
First, it is related to safety protection. This substance is toxic and irritating, or harmful to the human body. During production operations, be sure to be fully armed, wearing protective clothing, protective gloves, goggles and gas masks to prevent it from contact with the human body and inhalation. At the same time, the workplace should be well ventilated, and the harmful gases should be dispersed in time through ventilation facilities to reduce their concentration in the air.
Second, it involves the control of reaction conditions. Reactions involving 1-chloro-4-vinylbenzene often require strict conditions such as temperature, pressure, and catalyst. If the temperature is too high, the reaction may go out of control, and there is a risk of explosion; if the temperature is too low, the reaction rate will be slow, which will affect the production efficiency. Therefore, it is necessary to precisely control the reaction temperature and maintain temperature stability with the help of temperature control equipment. The pressure also needs to be carefully controlled. According to the specific requirements of the reaction, the pressure adjustment device can be used to achieve the appropriate pressure conditions. In addition, the choice and dosage of catalysts are also critical, which can change the rate of chemical reactions, improper dosage, or difficult to achieve the expected reaction effect.
Third, storage and transportation cannot be ignored. 1-Chloro-4-vinylbenzene should be stored in a cool, dry and ventilated place, away from fire and heat sources, to prevent it from being decomposed by heat or causing combustion and explosion. Storage containers should be well sealed to avoid leakage. During transportation, also ensure that the container is stable to prevent collisions and bumps from causing leakage. And transportation vehicles should be equipped with corresponding emergency treatment equipment and protective equipment, so that they can respond in time in case of emergencies.
Fourth, environmental protection issues in the production process cannot be ignored. Waste and exhaust gas generated by the reaction, or containing harmful substances, need to be properly handled and discharged after meeting environmental protection standards to avoid polluting the environment.
In short, the production process of 1-chloro-4-vinylbenzene is complex, and all links are closely interconnected. It is necessary to operate in strict accordance with regulations, paying attention to safety, reaction conditions, storage and transportation, and environmental protection issues in order to ensure smooth and efficient production, while ensuring the safety of personnel and the environment.
First, it is related to safety protection. This substance is toxic and irritating, or harmful to the human body. During production operations, be sure to be fully armed, wearing protective clothing, protective gloves, goggles and gas masks to prevent it from contact with the human body and inhalation. At the same time, the workplace should be well ventilated, and the harmful gases should be dispersed in time through ventilation facilities to reduce their concentration in the air.
Second, it involves the control of reaction conditions. Reactions involving 1-chloro-4-vinylbenzene often require strict conditions such as temperature, pressure, and catalyst. If the temperature is too high, the reaction may go out of control, and there is a risk of explosion; if the temperature is too low, the reaction rate will be slow, which will affect the production efficiency. Therefore, it is necessary to precisely control the reaction temperature and maintain temperature stability with the help of temperature control equipment. The pressure also needs to be carefully controlled. According to the specific requirements of the reaction, the pressure adjustment device can be used to achieve the appropriate pressure conditions. In addition, the choice and dosage of catalysts are also critical, which can change the rate of chemical reactions, improper dosage, or difficult to achieve the expected reaction effect.
Third, storage and transportation cannot be ignored. 1-Chloro-4-vinylbenzene should be stored in a cool, dry and ventilated place, away from fire and heat sources, to prevent it from being decomposed by heat or causing combustion and explosion. Storage containers should be well sealed to avoid leakage. During transportation, also ensure that the container is stable to prevent collisions and bumps from causing leakage. And transportation vehicles should be equipped with corresponding emergency treatment equipment and protective equipment, so that they can respond in time in case of emergencies.
Fourth, environmental protection issues in the production process cannot be ignored. Waste and exhaust gas generated by the reaction, or containing harmful substances, need to be properly handled and discharged after meeting environmental protection standards to avoid polluting the environment.
In short, the production process of 1-chloro-4-vinylbenzene is complex, and all links are closely interconnected. It is necessary to operate in strict accordance with regulations, paying attention to safety, reaction conditions, storage and transportation, and environmental protection issues in order to ensure smooth and efficient production, while ensuring the safety of personnel and the environment.
1-chloro-4-vinylbenzene impact on the environment
1-Chloro-4-vinylbenzene, the impact of this substance on the environment is quite complex. It is volatile, escapes into the atmosphere, or causes air quality to decline. Because of its chemical activity, or reacts with other substances in the atmosphere, secondary pollutants are produced, which damage the atmospheric environment, and can be breathed into the human body, endangering health.
In the aquatic environment, 1-chloro-4-vinylbenzene is insoluble, but it can adhere to suspended particles, settle in the bottom of the water and accumulate in the bottom mud. If aquatic organisms ingest or bioaccumulate, they will be transmitted along the food chain, resulting in an increase in the concentration of high-trophic organisms, affecting their growth and reproduction, and breaking the aquatic ecological balance.
In the soil, it diffuses slowly, adsorbs on soil particles, inhibits soil microbial activities, and affects soil ecological functions. If the plant root system is absorbed and transmitted to all parts of the plant, it will affect the growth and development, and humans or animals will also suffer from it if they eat such plants.
Furthermore, 1-chloro-4-vinylbenzene has potential persistence, is difficult to degrade in the environment, exists in the ecosystem for a long time, and continues to endanger the environment and organisms. Therefore, when it is produced, used and disposed of, it must be done with caution to prevent its release into the environment, so as to protect the ecological environment and human well-being.
In the aquatic environment, 1-chloro-4-vinylbenzene is insoluble, but it can adhere to suspended particles, settle in the bottom of the water and accumulate in the bottom mud. If aquatic organisms ingest or bioaccumulate, they will be transmitted along the food chain, resulting in an increase in the concentration of high-trophic organisms, affecting their growth and reproduction, and breaking the aquatic ecological balance.
In the soil, it diffuses slowly, adsorbs on soil particles, inhibits soil microbial activities, and affects soil ecological functions. If the plant root system is absorbed and transmitted to all parts of the plant, it will affect the growth and development, and humans or animals will also suffer from it if they eat such plants.
Furthermore, 1-chloro-4-vinylbenzene has potential persistence, is difficult to degrade in the environment, exists in the ecosystem for a long time, and continues to endanger the environment and organisms. Therefore, when it is produced, used and disposed of, it must be done with caution to prevent its release into the environment, so as to protect the ecological environment and human well-being.
What are the chemical properties of 1-chloro-4-vinylbenzene?
1-Chloro-4-vinylbenzene is p-chlorophenyl vinyl, which is an organic compound with unique chemical properties.
First, it has the properties of olefins. Due to carbon-containing double bonds, an addition reaction can occur. In case of bromine water, the π bond in the double bond is broken, and bromine atoms are added to the two carbon atoms to fade the bromine water. This is an electrophilic addition reaction. Its double bond electron cloud density is high and it is vulnerable to electrophilic attack. When adding hydrogen chloride, following the Markov rule, hydrogen atoms are added to the double bond carbon atoms containing more hydrogen to generate 1-chloro-4- (1-chloroethyl) benzene.
Second, due to the conjugation of the benzene ring with the double bond, the conjugated system increases the molecular stability. During the substitution reaction, the electron cloud density on the benzene ring is changed by the influence of the double bond. The chlorine atom is an ortho-para-localization group, and the double bond also plays a role in the electron cloud distribution of the benzene ring, so that the electrophilic substitution reaction mainly occurs in the ortho-position and para-position of the chlorine atom. For example, in a nitrification reaction, the nitro group mainly enters the adjacent and para-position of the chlorine atom to form the corresponding nitro compound.
Third, the double bond can undergo a polymerization reaction. Under the action of the initiator, the double bond opens and is connected to each other to form a polymer. This reaction is often used to prepare polymer materials containing p-chlor
Fourth, as a halogenated hydrocarbon, chlorine atoms can undergo substitution reactions. Under basic conditions, hydroxyl groups can replace chlorine atoms to form p-vinylphenol; under the action of nucleophiles, chlorine atoms can also be replaced by other nucleophilic groups, and then organic compounds with diverse structures can be synthesized.
First, it has the properties of olefins. Due to carbon-containing double bonds, an addition reaction can occur. In case of bromine water, the π bond in the double bond is broken, and bromine atoms are added to the two carbon atoms to fade the bromine water. This is an electrophilic addition reaction. Its double bond electron cloud density is high and it is vulnerable to electrophilic attack. When adding hydrogen chloride, following the Markov rule, hydrogen atoms are added to the double bond carbon atoms containing more hydrogen to generate 1-chloro-4- (1-chloroethyl) benzene.
Second, due to the conjugation of the benzene ring with the double bond, the conjugated system increases the molecular stability. During the substitution reaction, the electron cloud density on the benzene ring is changed by the influence of the double bond. The chlorine atom is an ortho-para-localization group, and the double bond also plays a role in the electron cloud distribution of the benzene ring, so that the electrophilic substitution reaction mainly occurs in the ortho-position and para-position of the chlorine atom. For example, in a nitrification reaction, the nitro group mainly enters the adjacent and para-position of the chlorine atom to form the corresponding nitro compound.
Third, the double bond can undergo a polymerization reaction. Under the action of the initiator, the double bond opens and is connected to each other to form a polymer. This reaction is often used to prepare polymer materials containing p-chlor
Fourth, as a halogenated hydrocarbon, chlorine atoms can undergo substitution reactions. Under basic conditions, hydroxyl groups can replace chlorine atoms to form p-vinylphenol; under the action of nucleophiles, chlorine atoms can also be replaced by other nucleophilic groups, and then organic compounds with diverse structures can be synthesized.
What are the main uses of 1-chloro-4-vinylbenzene?
1-Chloro-4-vinylbenzene, or p-chlorobenzene, is a key raw material in organic synthesis and is widely used in many fields.
First, in the field of polymer preparation, its role is crucial. P-chlorobenzene can be polymerized to produce chlorine-containing polystyrene polymers. These polymers have unique properties due to the introduction of chlorine atoms. If it exhibits better flame retardancy in certain specific environments, it can be applied to materials with strict fire protection requirements, such as electronic equipment casings, building insulation materials, etc., to add strong protection to their safety.
Second, in the coating industry, p-chlorobenzene also plays a key role. By introducing it into the coating resin system through an appropriate reaction, the performance of the coating can be significantly improved. For example, it can enhance the adhesion of the coating to the substrate, making the coating adhere more firmly to the surface of the object; it can also improve the chemical resistance of the coating, making the coating more resistant to acid and alkali and other chemicals, and prolonging the service life of the coating.
Third, in the synthesis of pharmaceutical intermediates, chlorostyrene is also indispensable. Due to its styrene ring and vinyl structure, it provides a rich reaction check point for organic synthesis. Through a series of chemical transformations, a variety of bioactive compounds can be prepared, laying the foundation for the development of new drugs. In the synthesis of many drug molecules, the participation of p-chlorobenzene can be seen, making outstanding contributions to human health.
In summary, 1-chloro-4-vinylbenzene plays an irreplaceable role in the fields of polymers, coatings, medicine and other fields due to its unique chemical structure, which is of great significance for promoting the development of related industries.
First, in the field of polymer preparation, its role is crucial. P-chlorobenzene can be polymerized to produce chlorine-containing polystyrene polymers. These polymers have unique properties due to the introduction of chlorine atoms. If it exhibits better flame retardancy in certain specific environments, it can be applied to materials with strict fire protection requirements, such as electronic equipment casings, building insulation materials, etc., to add strong protection to their safety.
Second, in the coating industry, p-chlorobenzene also plays a key role. By introducing it into the coating resin system through an appropriate reaction, the performance of the coating can be significantly improved. For example, it can enhance the adhesion of the coating to the substrate, making the coating adhere more firmly to the surface of the object; it can also improve the chemical resistance of the coating, making the coating more resistant to acid and alkali and other chemicals, and prolonging the service life of the coating.
Third, in the synthesis of pharmaceutical intermediates, chlorostyrene is also indispensable. Due to its styrene ring and vinyl structure, it provides a rich reaction check point for organic synthesis. Through a series of chemical transformations, a variety of bioactive compounds can be prepared, laying the foundation for the development of new drugs. In the synthesis of many drug molecules, the participation of p-chlorobenzene can be seen, making outstanding contributions to human health.
In summary, 1-chloro-4-vinylbenzene plays an irreplaceable role in the fields of polymers, coatings, medicine and other fields due to its unique chemical structure, which is of great significance for promoting the development of related industries.
What are 1-chloro-4-vinylbenzene synthesis methods?
1-Chloro-4-vinylbenzene is also an organic compound. The synthesis method of 1-chloro-4-vinylbenzene has been explored by many scholars in the past, and the common numbers are described here.
First, the Wittig reaction of 4-chlorobenzaldehyde with phosphorus-ylide reagent can be obtained. In the Gaiwittig reaction, the aldehyde or ketone interacts with phosphorus-ylide to produce olefins. 4-chlorobenzaldehyde meets a suitable phosphorus-ylide reagent. After the nucleophilic addition and elimination steps in the reaction mechanism, the carbonyl oxygen of the aldehyde group is replaced by vinyl, and then 1-chloro-4-vinylbenzene is obtained. The reaction conditions are mild, the selectivity is good, and the yield can also be observed. It is a common method for synthesis.
Second, it is obtained from the halogenation reaction of 4-chlorobenzene vinyl. With a suitable halogenating agent, such as N-chlorosuccinimide (NCS), in the presence of light or initiator, the allyl hydrogen of 4-chlorobenzene can be replaced by chlorine atoms, and then 1-chloro-4-vinylbenzene can be generated. This process requires attention to the control of reaction conditions. The light intensity and the amount of initiator are all related to the reaction process and product purity. However, the raw materials are easy to obtain, and the steps are relatively simple, which is also one of the ways to synthesize.
Third, 4-chlorobromobenzene and vinylboronic acid were synthesized by the Suzuki reaction. The Suzuki reaction is a coupling reaction between organoboron compounds and organohalides catalyzed by palladium. The bromine atom of 4-chlorobromobenzene and the boron atom of vinylboronic acid are coupled under the action of palladium catalyst and base to form a carbon-carbon bond to obtain 1-chloro-4-vinylbenzene. This reaction has the characteristics of high efficiency and strong selectivity. However, the cost of palladium catalyst is high, and the requirements for anhydrous and oxygen-free reaction system are strict. Practical application needs to be weighed.
First, the Wittig reaction of 4-chlorobenzaldehyde with phosphorus-ylide reagent can be obtained. In the Gaiwittig reaction, the aldehyde or ketone interacts with phosphorus-ylide to produce olefins. 4-chlorobenzaldehyde meets a suitable phosphorus-ylide reagent. After the nucleophilic addition and elimination steps in the reaction mechanism, the carbonyl oxygen of the aldehyde group is replaced by vinyl, and then 1-chloro-4-vinylbenzene is obtained. The reaction conditions are mild, the selectivity is good, and the yield can also be observed. It is a common method for synthesis.
Second, it is obtained from the halogenation reaction of 4-chlorobenzene vinyl. With a suitable halogenating agent, such as N-chlorosuccinimide (NCS), in the presence of light or initiator, the allyl hydrogen of 4-chlorobenzene can be replaced by chlorine atoms, and then 1-chloro-4-vinylbenzene can be generated. This process requires attention to the control of reaction conditions. The light intensity and the amount of initiator are all related to the reaction process and product purity. However, the raw materials are easy to obtain, and the steps are relatively simple, which is also one of the ways to synthesize.
Third, 4-chlorobromobenzene and vinylboronic acid were synthesized by the Suzuki reaction. The Suzuki reaction is a coupling reaction between organoboron compounds and organohalides catalyzed by palladium. The bromine atom of 4-chlorobromobenzene and the boron atom of vinylboronic acid are coupled under the action of palladium catalyst and base to form a carbon-carbon bond to obtain 1-chloro-4-vinylbenzene. This reaction has the characteristics of high efficiency and strong selectivity. However, the cost of palladium catalyst is high, and the requirements for anhydrous and oxygen-free reaction system are strict. Practical application needs to be weighed.
1-chloro-4-vinylbenzene What are the precautions during storage and transportation?
1-Chloro-4-vinylbenzene, this material has certain dangerous characteristics, and many matters need to be paid attention to during storage and transportation.
It is flammable and easy to burn in case of open flames and hot topics. When storing, it should be placed in a cool and ventilated warehouse. The temperature of the warehouse should not be too high to prevent danger. It should be kept away from fire and heat sources. The lighting and ventilation facilities in the warehouse should be explosion-proof, and the switch should also be located outside the warehouse. It should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed in storage to avoid violent reactions.
During transportation, the transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. Summer transportation should be selected in the morning and evening to avoid sun exposure. During transportation, ensure that the container does not leak, collapse, fall or damage. The trough (tank) car used during transportation should have a grounding chain, and holes can be set in the trough to reduce shock and generate static electricity. Road transportation should be carried according to the specified route, and do not stop in residential areas and densely populated areas. Loading and unloading personnel need to load and unload lightly to prevent damage to packaging and containers.
In short, the storage and transportation of 1-chloro-4-vinylbenzene must be carried out in strict accordance with regulations and must not be negligent to ensure the safety of personnel and the environment.
It is flammable and easy to burn in case of open flames and hot topics. When storing, it should be placed in a cool and ventilated warehouse. The temperature of the warehouse should not be too high to prevent danger. It should be kept away from fire and heat sources. The lighting and ventilation facilities in the warehouse should be explosion-proof, and the switch should also be located outside the warehouse. It should be stored separately from oxidants, acids, alkalis, etc., and should not be mixed in storage to avoid violent reactions.
During transportation, the transportation vehicle should be equipped with the corresponding variety and quantity of fire fighting equipment and leakage emergency treatment equipment. Summer transportation should be selected in the morning and evening to avoid sun exposure. During transportation, ensure that the container does not leak, collapse, fall or damage. The trough (tank) car used during transportation should have a grounding chain, and holes can be set in the trough to reduce shock and generate static electricity. Road transportation should be carried according to the specified route, and do not stop in residential areas and densely populated areas. Loading and unloading personnel need to load and unload lightly to prevent damage to packaging and containers.
In short, the storage and transportation of 1-chloro-4-vinylbenzene must be carried out in strict accordance with regulations and must not be negligent to ensure the safety of personnel and the environment.
1-chloro-4-vinylbenzene impact on the environment and human health
1-Chloro-4-vinylbenzene is an organic compound. This substance has an impact on both the environment and human health, as detailed below:
Effect on the environment
1. ** Water pollution **: If 1-chloro-4-vinylbenzene enters the water body, it will exist in the water body for a long time because it is insoluble in water and has certain chemical stability. After aquatic organisms are exposed, it may cause accumulation in the organism and affect its normal physiological functions. For example, fish contact may cause growth, reproduction inhibition, and even death. And through the food chain, it will accumulate in high-trophic organisms and affect the balance of the entire aquatic ecosystem.
2. ** Soil pollution **: In the soil, it will hinder the normal activities of soil microorganisms, affect the decomposition of soil organic matter and nutrient circulation. After plant roots are absorbed, it may affect plant growth and development, causing plants to be short, leaves to turn yellow, and yields to decrease. And its residues will affect soil quality for a long time and change soil physical and chemical properties.
3. ** Air pollution **: 1-chloro-4-vinylbenzene is volatile. After entering the atmosphere, it will photochemically react with other pollutants in the atmosphere, generating secondary pollutants such as ozone, which will aggravate air pollution. These pollutants will affect atmospheric visibility and harm the surrounding environment.
Effects on human health
1. ** Respiratory system effects **: Human inhalation of air containing 1-chloro-4-vinylbenzene can irritate the respiratory mucosa, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure, or cause chronic respiratory diseases, such as bronchitis, emphysema, etc., seriously affect respiratory function.
2. ** Skin and eye irritation **: Skin contact with this substance can cause allergic reactions such as redness, swelling, itching, and pain in the skin. If it is not carefully entered into the eyes, it will strongly irritate the eyes, causing symptoms such as eye pain, tears, and blurred vision. In severe cases, the cornea may be damaged, affecting vision.
3. ** Potential carcinogenic risk **: Studies have shown that 1-chloro-4-vinylbenzene may be potentially carcinogenic. Long-term exposure may increase the risk of cancer in the human body, such as inducing malignant tumors such as liver cancer and lung cancer, which seriously threaten life and health.
Effect on the environment
1. ** Water pollution **: If 1-chloro-4-vinylbenzene enters the water body, it will exist in the water body for a long time because it is insoluble in water and has certain chemical stability. After aquatic organisms are exposed, it may cause accumulation in the organism and affect its normal physiological functions. For example, fish contact may cause growth, reproduction inhibition, and even death. And through the food chain, it will accumulate in high-trophic organisms and affect the balance of the entire aquatic ecosystem.
2. ** Soil pollution **: In the soil, it will hinder the normal activities of soil microorganisms, affect the decomposition of soil organic matter and nutrient circulation. After plant roots are absorbed, it may affect plant growth and development, causing plants to be short, leaves to turn yellow, and yields to decrease. And its residues will affect soil quality for a long time and change soil physical and chemical properties.
3. ** Air pollution **: 1-chloro-4-vinylbenzene is volatile. After entering the atmosphere, it will photochemically react with other pollutants in the atmosphere, generating secondary pollutants such as ozone, which will aggravate air pollution. These pollutants will affect atmospheric visibility and harm the surrounding environment.
Effects on human health
1. ** Respiratory system effects **: Human inhalation of air containing 1-chloro-4-vinylbenzene can irritate the respiratory mucosa, causing symptoms such as cough, asthma, and breathing difficulties. Long-term exposure, or cause chronic respiratory diseases, such as bronchitis, emphysema, etc., seriously affect respiratory function.
2. ** Skin and eye irritation **: Skin contact with this substance can cause allergic reactions such as redness, swelling, itching, and pain in the skin. If it is not carefully entered into the eyes, it will strongly irritate the eyes, causing symptoms such as eye pain, tears, and blurred vision. In severe cases, the cornea may be damaged, affecting vision.
3. ** Potential carcinogenic risk **: Studies have shown that 1-chloro-4-vinylbenzene may be potentially carcinogenic. Long-term exposure may increase the risk of cancer in the human body, such as inducing malignant tumors such as liver cancer and lung cancer, which seriously threaten life and health.
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