Linshang Chemical
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1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene
Linshang Chemical
|
HS Code |
113956 |
| Chemical Formula | C7H5ClFNO2 |
| Molecular Weight | 191.57 |
| Appearance | Solid (usually) |
| Odor | Typical aromatic nitro - halide odor |
| Solubility In Water | Low solubility |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, toluene |
| Stability | Stable under normal conditions, but reactive to strong reducing or oxidizing agents |
| Hazard Class | Harmful (toxicity due to nitro and halide groups) |
As an accredited 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - chloro - 5 - fluoro - 2 - methyl - 4 - nitrobenzene: Packed in 100 - gram bottles for chemical use. |
| Storage | 1 - Chloro - 5 - fluoro - 2 - methyl - 4 - nitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture. Store it separately from oxidizing agents and reducing agents to avoid potential chemical reactions. |
| Shipping | 1 - chloro - 5 - fluoro - 2 - methyl - 4 - nitrobenzene is shipped in specialized, tightly - sealed containers compliant with chemical transport regulations. Shipment is via approved carriers, ensuring proper handling to prevent spills and maintain safety during transit. |
Competitive 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene in China?
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As a leading 1-Chloro-5-Fluoro-2-Methyl-4-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1-chloro-5-fluoro-2-methyl-4-nitrobenzene?
1 + -Deuterium-5 + -tritium-2 + -methyl-4 + -propylnaphthalene, this is an organic compound. Its physical properties are quite important and are related to many chemical applications and research.
First talk about its phase and melting point. Under normal temperature and pressure, the substance may be in a liquid state. Due to the intermolecular force, the number and structure of its carbon atoms make the intermolecular van der Waals force moderate, which does not reach the strength that solidifies the substance, nor is it weak enough to be gaseous. The specific values of its melting point and boiling point are closely related to the molecular structure. The existence of methyl and propyl groups changes the intermolecular distance and force, so that the melting point and boiling point are different from the naphthalene itself. Generally speaking, due to the introduction of side chains, the intermolecular arrangement is difficult to be regular, and the melting point may be lower than that of naphthalene; while the growth of side chains increases the intermolecular force, and the boiling point may be higher than that of naphthalene.
Then again, solubility. The compound is an organic substance, and according to the principle of similar miscibility, it has good solubility in organic solvents. For example, common non-polar organic solvents such as benzene and toluene have similar structures, which can effectively disperse the molecules of this compound and dissolve through intermolecular forces. In water, the solubility is poor. Water is a polar molecule, and the force between it and the non-polar organic molecule is weak and difficult to miscible.
In addition, density is also an important physical property. Its density may be smaller than that of water, because the molecules are mainly carbon and hydrogen, the atomic weight is relatively small, and the molecular structure is loose, and the mass per unit volume is lower than that of water.
In terms of volatility, although it is liquid at room temperature, it has certain volatility due to the characteristics of organic molecules. The presence of side chains affects the intermolecular forces, making it easy for some molecules to gain energy and escape from the liquid surface, causing them to evaporate in the air.
First talk about its phase and melting point. Under normal temperature and pressure, the substance may be in a liquid state. Due to the intermolecular force, the number and structure of its carbon atoms make the intermolecular van der Waals force moderate, which does not reach the strength that solidifies the substance, nor is it weak enough to be gaseous. The specific values of its melting point and boiling point are closely related to the molecular structure. The existence of methyl and propyl groups changes the intermolecular distance and force, so that the melting point and boiling point are different from the naphthalene itself. Generally speaking, due to the introduction of side chains, the intermolecular arrangement is difficult to be regular, and the melting point may be lower than that of naphthalene; while the growth of side chains increases the intermolecular force, and the boiling point may be higher than that of naphthalene.
Then again, solubility. The compound is an organic substance, and according to the principle of similar miscibility, it has good solubility in organic solvents. For example, common non-polar organic solvents such as benzene and toluene have similar structures, which can effectively disperse the molecules of this compound and dissolve through intermolecular forces. In water, the solubility is poor. Water is a polar molecule, and the force between it and the non-polar organic molecule is weak and difficult to miscible.
In addition, density is also an important physical property. Its density may be smaller than that of water, because the molecules are mainly carbon and hydrogen, the atomic weight is relatively small, and the molecular structure is loose, and the mass per unit volume is lower than that of water.
In terms of volatility, although it is liquid at room temperature, it has certain volatility due to the characteristics of organic molecules. The presence of side chains affects the intermolecular forces, making it easy for some molecules to gain energy and escape from the liquid surface, causing them to evaporate in the air.
What are the chemical properties of 1-chloro-5-fluoro-2-methyl-4-nitrobenzene?
This is a question related to chemical substances. However, the "1+-+%E6%B0%AF+-+5+-+%E6%B0%9F+-+2+-+%E7%94%B2%E5%9F%BA+-+4+-+%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84" mentioned is garbled, and it is difficult to accurately interpret its chemical structure and specific substances. If we use the style of "Tiangong Kaiwu", we should know that the properties of chemical substances are complex, and we need to specify the structure and composition before we can discuss their properties.
In the world of "Tiangong Kaiwu", although there were many applications and understandings of substances, the chemical theory at that time was not as complete as it is today. If it is a common chemical, it can be described in the way of cognition at that time according to its elemental composition and molecular structure.
If you want to discuss the chemical properties of a substance, you can probably view it from its reaction with other substances. In ancient times, or look at its reaction with fire, water, acid and alkali and other common substances. Combustible in case of fire, it is known that it is flammable; soluble or reactive in water is also its characteristic.
However, due to the unclear expression, it is difficult to say exactly the chemical properties of this "1+-+%E6%B0%AF+-+5+-+%E6%B0%9F+-+2+-+%E7%94%B2%E5%9F%BA+-+4+-+%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84". If the expression can be revised to clarify its chemical structure, or its properties can be analyzed in detail.
In the world of "Tiangong Kaiwu", although there were many applications and understandings of substances, the chemical theory at that time was not as complete as it is today. If it is a common chemical, it can be described in the way of cognition at that time according to its elemental composition and molecular structure.
If you want to discuss the chemical properties of a substance, you can probably view it from its reaction with other substances. In ancient times, or look at its reaction with fire, water, acid and alkali and other common substances. Combustible in case of fire, it is known that it is flammable; soluble or reactive in water is also its characteristic.
However, due to the unclear expression, it is difficult to say exactly the chemical properties of this "1+-+%E6%B0%AF+-+5+-+%E6%B0%9F+-+2+-+%E7%94%B2%E5%9F%BA+-+4+-+%E7%A1%9D%E5%9F%BA%E8%8B%AF%E7%9A%84". If the expression can be revised to clarify its chemical structure, or its properties can be analyzed in detail.
What are the main uses of 1-chloro-5-fluoro-2-methyl-4-nitrobenzene?
1 + -Deuterium-5 + -tritium-2 + -methyl-4 + -carbonyl benzoic acid, although not described in detail in "Tiangong Kaiwu", according to later research and related regulations, its use is quite extensive.
In the process of pharmaceutical preparation, it is a key intermediate. Because of the unique carbonyl and benzene ring structure in the molecule, it gives it special chemical activity. Carbonyl can be converted by various reactions, such as condensation with alcohols to form esters. This ester product is indispensable in the construction of many drug molecules, or enhances the lipid solubility of drugs, which is conducive to human absorption; or changes the spatial configuration of drugs, adjusts their ability to bind to targets, and then optimizes the efficacy.
In the field of material synthesis, it also plays an important role. With the structure of methyl and benzoic acid, it can participate in the construction of polymer polymers. Methyl can regulate the interaction between polymer chains and affect the physical properties such as material flexibility and glass transition temperature. The benzoic acid structure can introduce rigid benzene rings to improve the mechanical strength and thermal stability of materials. Special plastics or fibers synthesized from this material can be used in high-end fields such as aerospace, electronics and electrical appliances to meet the strict requirements for high performance of materials.
In the field of fine chemicals, it is an important starting material for the preparation of various additives. By chemically modifying it, additives with properties such as oxidation resistance and photostability can be prepared. Adding such substances to coatings and inks can prolong the service life of products, improve their weather resistance and anti-aging properties, and maintain good appearance and performance in different environments.
This compound has important uses in the fields of medicine, materials, and fine chemicals due to its structural properties, and is indeed a key material that cannot be ignored in chemical synthesis and industrial production.
In the process of pharmaceutical preparation, it is a key intermediate. Because of the unique carbonyl and benzene ring structure in the molecule, it gives it special chemical activity. Carbonyl can be converted by various reactions, such as condensation with alcohols to form esters. This ester product is indispensable in the construction of many drug molecules, or enhances the lipid solubility of drugs, which is conducive to human absorption; or changes the spatial configuration of drugs, adjusts their ability to bind to targets, and then optimizes the efficacy.
In the field of material synthesis, it also plays an important role. With the structure of methyl and benzoic acid, it can participate in the construction of polymer polymers. Methyl can regulate the interaction between polymer chains and affect the physical properties such as material flexibility and glass transition temperature. The benzoic acid structure can introduce rigid benzene rings to improve the mechanical strength and thermal stability of materials. Special plastics or fibers synthesized from this material can be used in high-end fields such as aerospace, electronics and electrical appliances to meet the strict requirements for high performance of materials.
In the field of fine chemicals, it is an important starting material for the preparation of various additives. By chemically modifying it, additives with properties such as oxidation resistance and photostability can be prepared. Adding such substances to coatings and inks can prolong the service life of products, improve their weather resistance and anti-aging properties, and maintain good appearance and performance in different environments.
This compound has important uses in the fields of medicine, materials, and fine chemicals due to its structural properties, and is indeed a key material that cannot be ignored in chemical synthesis and industrial production.
What are the synthesis methods of 1-chloro-5-fluoro-2-methyl-4-nitrobenzene?
To prepare 1-bromo-5-pentene-2-methyl-4-propylbenzene, the following methods can be used:
First, benzene is used as the starting material. First, benzene and propyl halide are catalyzed by Lewis acid (such as anhydrous aluminum chloride) through Fu-gram alkylation to obtain propylbenzene. Subsequently, propylbenzene interacts with bromine in the presence of light or peroxide. Due to the activity of α-hydrogen in the side chain of the benzene ring, free radical substitution can occur to generate α-bromopropylbenzene. Next, α-bromopropylbenzene is reacted with allyl Grignard reagent (prepared from allyl halide and magnesium in anhydrous ethyl ether), and the target product 1-bromo-5-pentene-2-methyl-4-propylbenzene can be obtained by nucleophilic substitution.
Second, 4-propylstyrene is used as the raw material. The carbon-carbon double bond in 4-propylstyrene can be added to hydrogen bromide. Under appropriate conditions, such as the presence of peroxide, the anti-Markov rule is followed, and the bromine atom is added to the double-bonded carbon atom containing more hydrogen, thereby generating 1-bromo-5-pentene-2-methyl-4-propylbenzene.
Third, start from 2-methyl-4-propylphenol. First, 2-methyl-4-propylphenol reacts with halopentene under basic conditions to form ether intermediates. After that, the intermediate is properly halogenated to introduce the ortho-position of the phenolic hydroxyl group into the bromine atom to obtain 1-bromo-5-pentene-2-methyl-4-propylbenzene. It is necessary to pay attention to the conditions of each reaction and possible side reactions. In practice, the reaction conditions should be optimized according to the specific situation to improve the yield and purity of the target product.
First, benzene is used as the starting material. First, benzene and propyl halide are catalyzed by Lewis acid (such as anhydrous aluminum chloride) through Fu-gram alkylation to obtain propylbenzene. Subsequently, propylbenzene interacts with bromine in the presence of light or peroxide. Due to the activity of α-hydrogen in the side chain of the benzene ring, free radical substitution can occur to generate α-bromopropylbenzene. Next, α-bromopropylbenzene is reacted with allyl Grignard reagent (prepared from allyl halide and magnesium in anhydrous ethyl ether), and the target product 1-bromo-5-pentene-2-methyl-4-propylbenzene can be obtained by nucleophilic substitution.
Second, 4-propylstyrene is used as the raw material. The carbon-carbon double bond in 4-propylstyrene can be added to hydrogen bromide. Under appropriate conditions, such as the presence of peroxide, the anti-Markov rule is followed, and the bromine atom is added to the double-bonded carbon atom containing more hydrogen, thereby generating 1-bromo-5-pentene-2-methyl-4-propylbenzene.
Third, start from 2-methyl-4-propylphenol. First, 2-methyl-4-propylphenol reacts with halopentene under basic conditions to form ether intermediates. After that, the intermediate is properly halogenated to introduce the ortho-position of the phenolic hydroxyl group into the bromine atom to obtain 1-bromo-5-pentene-2-methyl-4-propylbenzene. It is necessary to pay attention to the conditions of each reaction and possible side reactions. In practice, the reaction conditions should be optimized according to the specific situation to improve the yield and purity of the target product.
What are the precautions for storing and transporting 1-chloro-5-fluoro-2-methyl-4-nitrobenzene?
Fu 6-bromo-5-hexene-2-methyl-4-nonyl ether, when storing and transporting, pay attention to many matters.
First, because of its chemical properties, it is necessary to avoid open flames and hot topics. This is because the substance may be flammable. In case of open flames and hot topics, it is easy to cause the risk of combustion or even explosion, endangering the safety of people and property.
Second, it should be stored in a cool and ventilated warehouse. The appropriate temperature and humidity can ensure its chemical stability. If it is in a high temperature, humid place, or causes it to undergo chemical reactions, deterioration and failure.
Furthermore, when storing, it should be stored separately from oxidants, acids, etc., and should not be mixed. The cover may change unexpectedly due to contact with oxidants and acids, or severe chemical reactions.
During transportation, it is also necessary to drive slowly to prevent damage to the packaging. If the packaging is damaged and the substance leaks, it will not only be wasted, but also cause pollution to the environment, and will also endanger the health of transporters and surrounding people.
And when handling, it must be handled lightly to prevent damage to the container. Because it may be toxic and corrosive to a certain extent, once it leaks, the consequences are unimaginable.
All of these are 6-bromo-5-hexene-2-methyl-4-nonyl ethers that should be taken care of during storage and transportation. Those who act should be careful to ensure that everything goes smoothly and there is no disaster.
First, because of its chemical properties, it is necessary to avoid open flames and hot topics. This is because the substance may be flammable. In case of open flames and hot topics, it is easy to cause the risk of combustion or even explosion, endangering the safety of people and property.
Second, it should be stored in a cool and ventilated warehouse. The appropriate temperature and humidity can ensure its chemical stability. If it is in a high temperature, humid place, or causes it to undergo chemical reactions, deterioration and failure.
Furthermore, when storing, it should be stored separately from oxidants, acids, etc., and should not be mixed. The cover may change unexpectedly due to contact with oxidants and acids, or severe chemical reactions.
During transportation, it is also necessary to drive slowly to prevent damage to the packaging. If the packaging is damaged and the substance leaks, it will not only be wasted, but also cause pollution to the environment, and will also endanger the health of transporters and surrounding people.
And when handling, it must be handled lightly to prevent damage to the container. Because it may be toxic and corrosive to a certain extent, once it leaks, the consequences are unimaginable.
All of these are 6-bromo-5-hexene-2-methyl-4-nonyl ethers that should be taken care of during storage and transportation. Those who act should be careful to ensure that everything goes smoothly and there is no disaster.
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