1-(Chlorodifluoromethylsulfony)Benzene
Linshang Chemical
HS Code |
573792 |
Chemical Formula | C7H5ClF2O2S |
Molecular Weight | 226.63 |
As an accredited 1-(Chlorodifluoromethylsulfony)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 500g of 1-(chlorodifluoromethylsulfonyl)benzene packaged in a sealed, corrosion - resistant bottle. |
Storage | 1-(Chlorodifluoromethylsulfonyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container to prevent leakage and exposure to air and moisture. Store it separately from incompatible substances like oxidizing agents, reducing agents, and bases to avoid potential chemical reactions. |
Shipping | 1-(Chlorodifluoromethylsulfonyl)benzene is a chemical. Shipping requires proper packaging in accordance with regulations for hazardous chemicals. It must be labeled clearly and transported by carriers licensed for such substances. |
Competitive 1-(Chlorodifluoromethylsulfony)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading 1-(Chlorodifluoromethylsulfony)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
In the field of pharmaceutical chemistry, chemical modification and derivatization can be used to create compounds with novel biological activities, which can be used as the cornerstone of drug development. Due to the use of different substituents and reaction pathways, substances with high affinity and selectivity for specific disease targets can be generated, paving the way for the creation of new drugs.
In the field of materials science, it also has important uses. Due to its unique chemical properties, it may participate in the preparation of special functional materials. If the compound is introduced into the polymer material structure, it may improve the thermal stability, chemical stability and surface properties of the material. Make it useful in fields such as aerospace and electronic devices that require strict material properties.
In addition, in agricultural chemistry, through rational design and synthesis of compounds containing this structure, high-efficiency, low-toxicity and environmentally friendly pesticides can be developed. With its unique chemical activity, it has an effect on specific pests or pathogens, while reducing the adverse effects on the environment and non-target organisms. Overall, 1 - (chlorodifluoromethylsulfonyl) benzene plays an indispensable role in many fields and is of great significance to promoting the development of various fields.
When it comes to solubility, this substance exhibits good solubility in organic solvents, such as common ethanol, ether, acetone, etc., just like fish get water, and it is fused infinitely. However, in water, its solubility is extremely limited, just like the incompatibility of oil and water, only a very small amount is soluble.
Furthermore, its boiling point and melting point are also key physical properties. The boiling point is around a certain temperature range, and this temperature limit allows it to achieve gas-liquid transformation under certain conditions. The melting point also has a specific value. When the temperature drops below this point, the substance gradually solidifies from a liquid state to a solid state, just like water freezes and changes shape.
Its density is also different from that of water, showing a specific value. This value is related to its distribution in the mixed system, whether it floats on water or sinks underwater, depending on the density difference.
In addition, the chemical stability of the substance also needs attention. Under normal environmental conditions, its chemical properties are still stable. However, under extreme conditions such as specific chemical reagents, high temperatures, and strong acids and bases, chemical reactions may also be triggered, causing changes in its own structure and the formation of new substances. Just like in the stage of chemical reactions, the role is constantly changing.)
Looking at its structure, chlorine, difluoromethyl and sulfonyl groups are connected to the benzene ring. Chlorine atoms have certain electronegativity, which can affect the distribution of molecular electron clouds, change the density of benzene ring electron clouds, and then affect the activity of electrophilic substitution reactions. The fluorine atoms in difluoromethyl groups have extremely high electronegativity and significant strong electron-absorbing effect, which not only changes the molecular polarity, but also plays an important role in the reactivity and stability. Sulfonyl groups are strong electron-absorbing groups, which further affect the benzene ring electron cloud.
Usually, compounds containing such groups may have very different stability from benzene itself in some reactions due to the presence of electron-withdrawing groups. However, its stability is not static, and it may react under specific reagents and conditions, such as strong nucleophiles, high temperatures, and specific acid-base environments.
Under normal storage conditions, without the interference of active reagents, at room temperature and pressure, and in a dry environment, 1- (chlorodifluoromethylsulfonyl) benzene may remain relatively stable. However, chemical substances are variable, and it is difficult to generalize their absolute stability. Only by studying in detail according to specific reaction systems and conditions can we determine their chemical properties and stability.
First, benzenesulfonyl chloride is used as the starting material. First, benzenesulfonyl chloride interacts with chlorodifluoromethane under specific reaction conditions. This reaction needs to be carried out in a suitable solvent, such as polar aprotic solvents, such as dimethylformamide (DMF) or dimethyl sulfoxide (DMSO). During the reaction, an appropriate base, such as potassium carbonate or sodium carbonate, needs to be added to neutralize the acid generated by the reaction and promote the positive progress of the reaction. The amount of base, reaction temperature and time all have a great influence on the reaction result. Generally speaking, the temperature is controlled in a moderate range, such as between 50 and 80 degrees Celsius, and the reaction takes several hours, or the target product can be obtained.
Second, benzene can also be started from benzene. First, benzene is sulfonated. The commonly used sulfonation reagent is concentrated sulfuric acid or fuming sulfuric acid to form benzenesulfonic acid. Subsequently, the benzenesulfonic acid is chlorinated, and phosphorus trichloride or phosphorus pentachloride is used as a chlorination agent to convert it into benzenesulfonyl chloride. The obtained benzenesulfonyl chloride is then reacted with chlorodifluoromethane according to the above method, and finally 1 - (chlorodifluoromethylsulfonyl) benzene is obtained. Although there are
Or there may be other methods, such as the reaction catalyzed by transition metals. Appropriate transition metal catalysts, such as palladium, nickel and other complexes, are selected to couple the sulfur-containing reagents with halogenated aromatics and chlorodifluoromethyl under mild conditions. Although this method has the advantages of high efficiency and good selectivity, the catalyst cost is high, and the reaction equipment and operation requirements are also quite strict.
Preparation of 1 - (chlorodifluoromethylsulfonyl) benzene is diverse, with advantages and disadvantages. The appropriate method needs to be weighed according to actual needs and conditions.
The first thing to bear the brunt is related to the storage environment. This substance should be placed in a cool, dry and well ventilated place. Avoid open flames and hot topics, and cover them because they may be flammable, or dangerous under hot topics. The temperature of the warehouse should be controlled, not too high, to prevent its properties from changing or causing dangerous reactions. And it needs to be stored separately from oxidants, bases, etc., and must not be mixed. Because of its active chemical properties, contact with other substances, or violent chemical reactions, causing accidents.
Furthermore, when transporting, there is also attention. The packaging must be tight to ensure that there is no risk of leakage. During transportation, the traffic should be stable to avoid bumps and collisions, so as to avoid material leakage caused by damaged packaging. The transportation vehicle should be equipped with the corresponding variety and quantity of fire-fighting equipment and leakage emergency treatment equipment. The escort personnel must be familiar with the nature of this substance and emergency disposal methods, and pay attention at any time on the way. If there is any abnormality, they should be dealt with immediately. When loading and unloading, the operator should wear appropriate protective equipment, pack and unload lightly, and do not operate brutally to prevent packaging damage.
All of these are 1 - (chlorodifluoromethylsulfonyl) benzene. Pay attention when storing and transporting, in order to ensure safety and avoid disasters.

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