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1-(Chlorodiphenylmethyl)-4-Methoxybenzene
Linshang Chemical
|
HS Code |
441259 |
| Chemical Formula | C14H13ClO |
| Molar Mass | 232.706 g/mol |
As an accredited 1-(Chlorodiphenylmethyl)-4-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram quantity of 1-(chlorodiphenylmethyl)-4 - methoxybenzene in sealed chemical - grade bags. |
| Storage | 1-(Chlorodiphenylmethyl)-4-methoxybenzene should be stored in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly closed container to prevent moisture and air exposure. Store it separately from incompatible substances like oxidizing agents to avoid potential chemical reactions. |
| Shipping | 1-(Chlorodiphenylmethyl)-4 -methoxybenzene is shipped in accordance with strict chemical transport regulations. It's packaged securely in appropriate containers to prevent leakage during transit to ensure safety. |
Competitive 1-(Chlorodiphenylmethyl)-4-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 1-(Chlorodiphenylmethyl)-4-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1- (chlorodiphenylmethyl) -4-methoxybenzene?
1 - (chlorodiphenyl methyl) - 4 - methoxybenzene, this is an organic compound with a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. Due to the delicacy of organic synthesis, such intermediates are needed to build complex drug molecular structures. In the process of many drug research and development, 1 - (chlorodiphenyl methyl) - 4 - methoxybenzene can participate in a variety of chemical reactions with its unique chemical structure, helping to synthesize compounds with specific biological activities, thus paving the way for the creation of new drugs.
It can also be seen in the field of materials science. With the advance of science and technology, the demand for materials with special properties is increasing. 1 - (chlorodiphenyl methyl) - 4 - methoxybenzene can be processed by a specific process and integrated into the material synthesis process, giving the material unique properties such as improved optical properties and thermal stability. For example, in the preparation of some functional polymer materials, it may be used as a structural modification unit to optimize the overall properties of the material and meet the strict requirements of different fields.
In addition, in the field of fine chemicals, it also has important functions. Fine chemical products pursue high quality and high added value. 1 - (chlorodiphenyl) - 4 - methoxybenzene can be used to synthesize various fine chemicals, such as special fragrances, dye additives, etc. Through precise chemical reactions, it can add unique properties and characteristics to fine chemical products and enhance their competitiveness in the market. In short, 1 - (chlorodiphenylmethyl) - 4 - methoxybenzene plays an indispensable role in many fields and is of great significance to promote the development of related industries.
It can also be seen in the field of materials science. With the advance of science and technology, the demand for materials with special properties is increasing. 1 - (chlorodiphenyl methyl) - 4 - methoxybenzene can be processed by a specific process and integrated into the material synthesis process, giving the material unique properties such as improved optical properties and thermal stability. For example, in the preparation of some functional polymer materials, it may be used as a structural modification unit to optimize the overall properties of the material and meet the strict requirements of different fields.
In addition, in the field of fine chemicals, it also has important functions. Fine chemical products pursue high quality and high added value. 1 - (chlorodiphenyl) - 4 - methoxybenzene can be used to synthesize various fine chemicals, such as special fragrances, dye additives, etc. Through precise chemical reactions, it can add unique properties and characteristics to fine chemical products and enhance their competitiveness in the market. In short, 1 - (chlorodiphenylmethyl) - 4 - methoxybenzene plays an indispensable role in many fields and is of great significance to promote the development of related industries.
What are the physical properties of 1- (chlorodiphenylmethyl) -4-methoxybenzene
1 - (chlorodiphenyl methyl) - 4 -methoxybenzene, is one of the organic compounds. Its physical properties are particularly important, related to its application and characteristics.
First of all, its appearance, under room temperature and pressure, is mostly white to light yellow crystalline powder. It looks like fine sand, pure color, uniform texture, and slightly glossy under light. This is its intuitive physical characterization.
The melting point is about [X] ° C, and the melting point is established. At the corresponding temperature, the substance gradually melts from a solid state to a liquid state. During this transition, it needs to absorb specific heat to break its lattice structure. The exact value of the melting point is a key basis for the identification and purification of this substance.
Furthermore, the boiling point is usually around [X] ° C. At this temperature, the vapor pressure of the compound is equal to the external pressure, and the liquid state quickly turns into a gaseous state and escapes in the surrounding space. The determination of boiling point is of great significance in separation, purification and industrial production.
Solubility, 1 - (chlorodiphenyl methyl) - 4 - methoxybenzene is soluble in organic solvents such as ethanol, ether, chloroform, etc. In ethanol, it can be uniformly dispersed to form a clear and transparent solution, like a fish swimming in water, and the two blend seamlessly. However, in water, its solubility is poor, and it is mostly suspended in solid particles. It is like a stone sinking into the sea, and it is difficult to mix with water. The difference in solubility is due to the characteristics of its molecular structure.
In terms of density, it is about [X] g/cm ³. This value indicates that the mass of its unit volume is related to its physical behavior such as sedimentation and floating in different media. The measurement of density can provide necessary parameters for the storage, transportation and application of substances.
Finally, this object has a certain smell, but it is not a pungent odor. It is a weak special smell that needs to be detected by close sniffing. This smell is also one end of its physical properties, and may also affect some specific application scenarios.
First of all, its appearance, under room temperature and pressure, is mostly white to light yellow crystalline powder. It looks like fine sand, pure color, uniform texture, and slightly glossy under light. This is its intuitive physical characterization.
The melting point is about [X] ° C, and the melting point is established. At the corresponding temperature, the substance gradually melts from a solid state to a liquid state. During this transition, it needs to absorb specific heat to break its lattice structure. The exact value of the melting point is a key basis for the identification and purification of this substance.
Furthermore, the boiling point is usually around [X] ° C. At this temperature, the vapor pressure of the compound is equal to the external pressure, and the liquid state quickly turns into a gaseous state and escapes in the surrounding space. The determination of boiling point is of great significance in separation, purification and industrial production.
Solubility, 1 - (chlorodiphenyl methyl) - 4 - methoxybenzene is soluble in organic solvents such as ethanol, ether, chloroform, etc. In ethanol, it can be uniformly dispersed to form a clear and transparent solution, like a fish swimming in water, and the two blend seamlessly. However, in water, its solubility is poor, and it is mostly suspended in solid particles. It is like a stone sinking into the sea, and it is difficult to mix with water. The difference in solubility is due to the characteristics of its molecular structure.
In terms of density, it is about [X] g/cm ³. This value indicates that the mass of its unit volume is related to its physical behavior such as sedimentation and floating in different media. The measurement of density can provide necessary parameters for the storage, transportation and application of substances.
Finally, this object has a certain smell, but it is not a pungent odor. It is a weak special smell that needs to be detected by close sniffing. This smell is also one end of its physical properties, and may also affect some specific application scenarios.
What are the chemical properties of 1- (chlorodiphenylmethyl) -4-methoxybenzene
1 - (chlorodiphenylmethyl) - 4 -methoxybenzene, this is an organic compound with unique chemical properties. Its molecule contains the structure of chlorodiphenylmethyl and methoxybenzene, and because of this structure, it presents a series of characteristics.
The first describes its physical properties. At room temperature, or in a solid state, the melting point or depends on the intermolecular force. There are chlorine atoms, phenyl groups and methoxy groups in the molecule, resulting in complex intermolecular forces. Chlorine atoms are highly electronegative, which can cause molecules to be polar, affecting the melting point and solubility. Generally speaking, in organic solvents such as ethanol and ether, it may have good solubility. Due to the principle of "similar miscibility", its organic structure is compatible with the structure of organic solvents.
Re-discussion of chemical properties. First, the properties of the benzene ring are active. The benzene ring has a conjugated system and is prone to electrophilic substitution reactions. Both chlorodiphenyl methyl and methoxy groups are benzene ring substituents, and methoxy groups are the power supply sub-groups, which can enhance the electron cloud density of the benzene ring, making the benzene ring more susceptible to attack by electrophilic reagents. In halogenation, nitrification, sulfonation and other electrophilic substitution reactions, the reactivity is improved. Second, the activity of chlorine atoms in chlorodiphenyl methyl is also critical. Chlorine atoms can undergo substitution reactions, such as reacting with nucleophiles and being replaced by other groups. Third, methoxy groups can participate in specific reactions. In case of strong acids, or protonation occurs, changing the distribution of molecular electron clouds and affecting The chemical properties of 1 - (chlorodiphenylmethyl) - 4 - methoxybenzene are determined by its structure, and it can be used as an important intermediate in the field of organic synthesis.
The first describes its physical properties. At room temperature, or in a solid state, the melting point or depends on the intermolecular force. There are chlorine atoms, phenyl groups and methoxy groups in the molecule, resulting in complex intermolecular forces. Chlorine atoms are highly electronegative, which can cause molecules to be polar, affecting the melting point and solubility. Generally speaking, in organic solvents such as ethanol and ether, it may have good solubility. Due to the principle of "similar miscibility", its organic structure is compatible with the structure of organic solvents.
Re-discussion of chemical properties. First, the properties of the benzene ring are active. The benzene ring has a conjugated system and is prone to electrophilic substitution reactions. Both chlorodiphenyl methyl and methoxy groups are benzene ring substituents, and methoxy groups are the power supply sub-groups, which can enhance the electron cloud density of the benzene ring, making the benzene ring more susceptible to attack by electrophilic reagents. In halogenation, nitrification, sulfonation and other electrophilic substitution reactions, the reactivity is improved. Second, the activity of chlorine atoms in chlorodiphenyl methyl is also critical. Chlorine atoms can undergo substitution reactions, such as reacting with nucleophiles and being replaced by other groups. Third, methoxy groups can participate in specific reactions. In case of strong acids, or protonation occurs, changing the distribution of molecular electron clouds and affecting The chemical properties of 1 - (chlorodiphenylmethyl) - 4 - methoxybenzene are determined by its structure, and it can be used as an important intermediate in the field of organic synthesis.
What are the synthesis methods of 1- (chlorodiphenylmethyl) -4-methoxybenzene
1 - (chlorodiphenyl methyl) - 4 - methoxybenzene, there are various ways to synthesize it.
First, it can be started from 4 - methoxybenzaldehyde. First, 4 - methoxybenzaldehyde and diphenylchloromethane are heated and stirred in a suitable base, such as potassium carbonate, in an organic solvent, such as acetonitrile. In this process, the base can capture the hydrogen at the active check point of 4 - methoxybenzaldehyde, and then undergo nucleophilic substitution with diphenylchloromethane. During the reaction, pay attention to the control of temperature. If the temperature is too high, it may cause side reactions and lead to impure products; if the temperature is too low, the reaction rate will be slow and take a long time. After the reaction is completed, the product can be purified by conventional separation methods, such as extraction, column chromatography, etc., to obtain 1 - (chlorodiphenylmethyl) - 4 - methoxybenzene.
Second, 4 - methoxyphenylmagnesium bromide and diphenylchloromethane can also be used as raw materials. In anhydrous ether or tetrahydrofuran solvents, under low temperature and nitrogen protection, 4 - methoxyphenylmagnesium bromide is reacted with diphenylchloromethane. This is a reaction involving Grignard reagents. Grignard reagents have high activity and strict requirements for reaction conditions. An anhydrous and anaerobic environment is indispensable, otherwise Grignard reagents are prone to decomposition and failure. After the reaction is completed, the target product can also be obtained through hydrolysis, extraction, drying, distillation and other steps.
Third, 4-methoxyaniline can also be used. First, 4-methoxyaniline is diazotized, and then it reacts with diphenylchloromethane under the catalysis of a specific copper salt. The diazotization step needs to be carried out in a low temperature acidic environment to ensure the stability of the diazonium salt. When catalyzed by copper salts, the type and dosage have a great influence on the reaction and must be precisely controlled. The follow-up still needs to be separated and purified to refine the product.
Each of these synthetic methods has its own advantages and disadvantages, and it is necessary to choose the best one according to the actual situation, such as the availability of raw materials, cost, and purity requirements of the product.
First, it can be started from 4 - methoxybenzaldehyde. First, 4 - methoxybenzaldehyde and diphenylchloromethane are heated and stirred in a suitable base, such as potassium carbonate, in an organic solvent, such as acetonitrile. In this process, the base can capture the hydrogen at the active check point of 4 - methoxybenzaldehyde, and then undergo nucleophilic substitution with diphenylchloromethane. During the reaction, pay attention to the control of temperature. If the temperature is too high, it may cause side reactions and lead to impure products; if the temperature is too low, the reaction rate will be slow and take a long time. After the reaction is completed, the product can be purified by conventional separation methods, such as extraction, column chromatography, etc., to obtain 1 - (chlorodiphenylmethyl) - 4 - methoxybenzene.
Second, 4 - methoxyphenylmagnesium bromide and diphenylchloromethane can also be used as raw materials. In anhydrous ether or tetrahydrofuran solvents, under low temperature and nitrogen protection, 4 - methoxyphenylmagnesium bromide is reacted with diphenylchloromethane. This is a reaction involving Grignard reagents. Grignard reagents have high activity and strict requirements for reaction conditions. An anhydrous and anaerobic environment is indispensable, otherwise Grignard reagents are prone to decomposition and failure. After the reaction is completed, the target product can also be obtained through hydrolysis, extraction, drying, distillation and other steps.
Third, 4-methoxyaniline can also be used. First, 4-methoxyaniline is diazotized, and then it reacts with diphenylchloromethane under the catalysis of a specific copper salt. The diazotization step needs to be carried out in a low temperature acidic environment to ensure the stability of the diazonium salt. When catalyzed by copper salts, the type and dosage have a great influence on the reaction and must be precisely controlled. The follow-up still needs to be separated and purified to refine the product.
Each of these synthetic methods has its own advantages and disadvantages, and it is necessary to choose the best one according to the actual situation, such as the availability of raw materials, cost, and purity requirements of the product.
What are the precautions for 1- (chlorodiphenylmethyl) -4-methoxybenzene during use?
1 - (Chlorodiphenylmethyl) - 4 - methoxybenzene, this is an organic compound. During use, many matters need to be carefully paid attention to.
Bear the brunt of it, and safety protection must not be ignored. Because it may be toxic and irritating, be sure to prepare protective equipment when operating. For example, wear appropriate protective gloves to prevent direct contact with the skin, causing skin allergies, burns and other adverse consequences; wear protective glasses to avoid splashing into the eyes and causing damage to the eyes; if conditions permit, it is advisable to wear a gas mask to prevent inhalation of its volatile gaseous substances and damage to the respiratory system.
Furthermore, storage is also particular. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its flammability, it is at risk of encountering open flames, hot topics or triggering combustion and explosion. At the same time, it should be stored separately from oxidants, acids, etc., and must not be mixed to prevent chemical reactions from occurring, resulting in dangerous conditions.
The use environment should not be ignored. The operation should be carried out in the fume hood to ensure that the volatile gaseous substances can be discharged in time, reduce the concentration in the air, and reduce the harm to the human body. If used in an unventilated environment, the accumulation of gaseous substances will not only endanger health, but also pose a safety hazard.
The use process must be standardized. Strictly follow the established operating procedures to precisely control the amount of use and reaction conditions. Changes in reaction conditions, such as temperature, pH, reaction time, etc., may have a significant impact on the reaction result, or cause the formation of impurities, or reduce the yield.
Emergency response plans are also indispensable. In the event of a leak, the surrounding personnel should be evacuated immediately to isolate the leakage area. In the case of a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite; in the case of a large amount of leakage, it is necessary to build a dike or dig a pit for containment, and transfer it to a special collection container with an explosion-proof pump for proper disposal. If it accidentally touches the skin or eyes, it should be quickly rinsed with a large amount of flowing water. In severe cases, seek medical attention in time.
Bear the brunt of it, and safety protection must not be ignored. Because it may be toxic and irritating, be sure to prepare protective equipment when operating. For example, wear appropriate protective gloves to prevent direct contact with the skin, causing skin allergies, burns and other adverse consequences; wear protective glasses to avoid splashing into the eyes and causing damage to the eyes; if conditions permit, it is advisable to wear a gas mask to prevent inhalation of its volatile gaseous substances and damage to the respiratory system.
Furthermore, storage is also particular. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its flammability, it is at risk of encountering open flames, hot topics or triggering combustion and explosion. At the same time, it should be stored separately from oxidants, acids, etc., and must not be mixed to prevent chemical reactions from occurring, resulting in dangerous conditions.
The use environment should not be ignored. The operation should be carried out in the fume hood to ensure that the volatile gaseous substances can be discharged in time, reduce the concentration in the air, and reduce the harm to the human body. If used in an unventilated environment, the accumulation of gaseous substances will not only endanger health, but also pose a safety hazard.
The use process must be standardized. Strictly follow the established operating procedures to precisely control the amount of use and reaction conditions. Changes in reaction conditions, such as temperature, pH, reaction time, etc., may have a significant impact on the reaction result, or cause the formation of impurities, or reduce the yield.
Emergency response plans are also indispensable. In the event of a leak, the surrounding personnel should be evacuated immediately to isolate the leakage area. In the case of a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite; in the case of a large amount of leakage, it is necessary to build a dike or dig a pit for containment, and transfer it to a special collection container with an explosion-proof pump for proper disposal. If it accidentally touches the skin or eyes, it should be quickly rinsed with a large amount of flowing water. In severe cases, seek medical attention in time.
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