Linshang Chemical
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(1-Chloroethyl)Benzene
Linshang Chemical
|
HS Code |
102712 |
| Chemical Formula | C8H9Cl |
| Molar Mass | 140.61 g/mol |
| Appearance | Colorless to pale - yellow liquid |
| Odor | Pungent odor |
| Density | 1.065 g/cm³ (at 20°C) |
| Boiling Point | 197 - 198°C |
| Melting Point | -43°C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like ethanol, ether |
| Flash Point | 72°C |
| Vapor Pressure | 0.25 mmHg at 20°C |
As an accredited (1-Chloroethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500 - gram bottle of (1 - chloroethyl)benzene, well - sealed for safe storage. |
| Storage | (1 - chloroethyl)benzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly - sealed container to prevent leakage. Store it separately from oxidizing agents, acids, and bases. Use storage facilities compliant with safety regulations to avoid potential chemical reactions and ensure safety. |
| Shipping | (1 - chloroethyl)benzene is shipped in tightly - sealed, corrosion - resistant containers. It must be transported in accordance with hazardous chemical regulations, ensuring proper labeling and segregation from incompatible substances during transit. |
Competitive (1-Chloroethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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What are the chemical properties of (1-chloroethyl) benzene
(1-Chloroethyl) benzene is also an organic compound. In its molecular structure, the benzene ring is connected to the chlorine-containing ethyl group. This compound has unique chemical properties and has attracted much attention in the field of organic synthesis.
Its chemical properties are the first to promote nucleophilic substitution. Because chlorine atoms are quite electronegative, the carbon atoms connected to them are partially positive and vulnerable to attack by nucleophilic reagents. Nucleophilic reagents such as alcohols, amines, etc., can react with chlorine atoms in (1-chloroethyl) benzene to form new organic compounds. For example, with alcohol as a nucleophilic reagent, under the catalysis of an appropriate base, the oxygen atom of the alcohol attacks the partially positively charged carbon atom in (1-chloroethyl) benzene, and the chlorine atom leaves to form ether compounds. This reaction is an important way to construct carbon-oxygen bonds, and is widely used in the synthesis of fragrances, pharmaceutical intermediates, etc.
Furthermore, (1-chloroethyl) benzene can be eliminated. Under the action of a strong base, the chlorine atom and the hydrogen atom on the adjacent carbon atom can be removed to form a carbon-carbon double bond to form a styrene compound. The reaction conditions are harsh, requiring a specific strong base and a suitable temperature, so it is an effective means to prepare styrene derivatives, which are crucial in the synthesis of polymer materials.
In addition, the presence of (1-chloroethyl) benzene ring is aromatic and can participate in the electrophilic substitution reaction on the benzene ring. Although the presence of chloroethyl groups has an impact on the electron cloud density distribution of the benzene ring, under appropriate conditions, electrophilic reagents can still attack the benzene ring, and reactions such as halogenation, nitrification, and sulfonation can occur. Different substituents are introduced into the benzene ring, thereby preparing organic compounds with diverse structures and enriching the way of organic synthesis.
Its chemical properties are the first to promote nucleophilic substitution. Because chlorine atoms are quite electronegative, the carbon atoms connected to them are partially positive and vulnerable to attack by nucleophilic reagents. Nucleophilic reagents such as alcohols, amines, etc., can react with chlorine atoms in (1-chloroethyl) benzene to form new organic compounds. For example, with alcohol as a nucleophilic reagent, under the catalysis of an appropriate base, the oxygen atom of the alcohol attacks the partially positively charged carbon atom in (1-chloroethyl) benzene, and the chlorine atom leaves to form ether compounds. This reaction is an important way to construct carbon-oxygen bonds, and is widely used in the synthesis of fragrances, pharmaceutical intermediates, etc.
Furthermore, (1-chloroethyl) benzene can be eliminated. Under the action of a strong base, the chlorine atom and the hydrogen atom on the adjacent carbon atom can be removed to form a carbon-carbon double bond to form a styrene compound. The reaction conditions are harsh, requiring a specific strong base and a suitable temperature, so it is an effective means to prepare styrene derivatives, which are crucial in the synthesis of polymer materials.
In addition, the presence of (1-chloroethyl) benzene ring is aromatic and can participate in the electrophilic substitution reaction on the benzene ring. Although the presence of chloroethyl groups has an impact on the electron cloud density distribution of the benzene ring, under appropriate conditions, electrophilic reagents can still attack the benzene ring, and reactions such as halogenation, nitrification, and sulfonation can occur. Different substituents are introduced into the benzene ring, thereby preparing organic compounds with diverse structures and enriching the way of organic synthesis.
What are the main uses of (1-chloroethyl) benzene?
(1-Chloroethyl) benzene has a wide range of uses. In the field of organic synthesis, this is a key intermediary. Due to its unique structure, chlorine atoms are active, and many other types of organic compounds can be derived through many chemical reactions, such as nucleophilic substitution reactions.
If it encounters alcohols, under suitable conditions, chlorine atoms can be replaced by alcohol-oxy groups to generate ether substances, which is of great significance in the preparation of fine chemical products, such as the synthesis of flavors and pharmaceutical intermediates.
In the field of materials science, (1-chloroethyl) benzene also has applications. It can participate in the polymerization reaction and become the structural unit of the polymer, giving the material different properties.
Furthermore, in some specific catalytic reaction systems, (1-chloroethyl) benzene can act as a ligand to assist the catalyst to exert its efficiency and affect the rate and selectivity of the reaction.
In industrial production practice, it is also common. As a solvent, it has good solubility to some organic substances and can be used in the manufacture of coatings, inks and other products to help improve the performance and quality of products.
To sum up, (1-chloroethyl) benzene is indispensable in many fields such as organic synthesis, materials science, and industrial production, and is actually a widely used organic compound.
If it encounters alcohols, under suitable conditions, chlorine atoms can be replaced by alcohol-oxy groups to generate ether substances, which is of great significance in the preparation of fine chemical products, such as the synthesis of flavors and pharmaceutical intermediates.
In the field of materials science, (1-chloroethyl) benzene also has applications. It can participate in the polymerization reaction and become the structural unit of the polymer, giving the material different properties.
Furthermore, in some specific catalytic reaction systems, (1-chloroethyl) benzene can act as a ligand to assist the catalyst to exert its efficiency and affect the rate and selectivity of the reaction.
In industrial production practice, it is also common. As a solvent, it has good solubility to some organic substances and can be used in the manufacture of coatings, inks and other products to help improve the performance and quality of products.
To sum up, (1-chloroethyl) benzene is indispensable in many fields such as organic synthesis, materials science, and industrial production, and is actually a widely used organic compound.
What is the preparation method of (1-chloroethyl) benzene
The method of preparing (1-chloroethyl) benzene often uses benzene and chloroethane as raw materials, and uses the power of a catalyst to carry out the Fu-gram alkylation reaction. The details are as follows:
Prepare a clean and dry reaction vessel, preferably made of glass, because of its stable chemical properties, it is not easy to interact with the reactants. In this vessel, pour an appropriate amount of benzene and chloroethane in a certain proportion. Benzene is an organic compound with a cyclic structure and relatively stable properties; chloroethane is a halogenated hydrocarbon, in which the chlorine atom has a certain activity and can be the key to the reaction.
Add an appropriate amount of anhydrous aluminum trichloride as a catalyst. Anhydrous aluminum trichloride has a significant effect in the alkylation reaction of Fu-g, which can promote the polarization of the bond between the chlorine atom and the ethyl group in chloroethane, so that the ethyl group is more likely to break away from the chlorine atom, and then the electrophilic substitution reaction occurs with the benzene ring.
When reacting, the temperature needs to be controlled. Generally speaking, the temperature of the reaction system should be maintained in a moderate range, not too high, so as to avoid side reactions; nor should it be too low, causing the reaction rate to be too slow. The method of water bath or oil bath can be used to accurately control the temperature.
During the reaction process, pay close attention to the reaction phenomenon. Initially, the reactants are mixed evenly, and the colorless and transparent liquid gradually changes. As the reaction proceeds, the system or existing color changes, and there are bubbles
After the reaction is completed, pour the reaction mixture into an appropriate amount of ice water to hydrolyze the excess anhydrous aluminum trichloride and separate the product from the catalyst. After that, the organic phase is obtained through liquid separation operation. The organic phase is purified by distillation, and the unreacted benzene and chloroethane are removed. The fraction in a specific temperature range is collected to obtain the (1-chloroethyl) benzene product. In this way, pure (1-chloroethyl) benzene can be obtained.
Prepare a clean and dry reaction vessel, preferably made of glass, because of its stable chemical properties, it is not easy to interact with the reactants. In this vessel, pour an appropriate amount of benzene and chloroethane in a certain proportion. Benzene is an organic compound with a cyclic structure and relatively stable properties; chloroethane is a halogenated hydrocarbon, in which the chlorine atom has a certain activity and can be the key to the reaction.
Add an appropriate amount of anhydrous aluminum trichloride as a catalyst. Anhydrous aluminum trichloride has a significant effect in the alkylation reaction of Fu-g, which can promote the polarization of the bond between the chlorine atom and the ethyl group in chloroethane, so that the ethyl group is more likely to break away from the chlorine atom, and then the electrophilic substitution reaction occurs with the benzene ring.
When reacting, the temperature needs to be controlled. Generally speaking, the temperature of the reaction system should be maintained in a moderate range, not too high, so as to avoid side reactions; nor should it be too low, causing the reaction rate to be too slow. The method of water bath or oil bath can be used to accurately control the temperature.
During the reaction process, pay close attention to the reaction phenomenon. Initially, the reactants are mixed evenly, and the colorless and transparent liquid gradually changes. As the reaction proceeds, the system or existing color changes, and there are bubbles
After the reaction is completed, pour the reaction mixture into an appropriate amount of ice water to hydrolyze the excess anhydrous aluminum trichloride and separate the product from the catalyst. After that, the organic phase is obtained through liquid separation operation. The organic phase is purified by distillation, and the unreacted benzene and chloroethane are removed. The fraction in a specific temperature range is collected to obtain the (1-chloroethyl) benzene product. In this way, pure (1-chloroethyl) benzene can be obtained.
What are the precautions for (1-chloroethyl) benzene in storage and transportation?
For (1-chloroethyl) benzene, many things should be paid attention to during storage and transportation.
First word storage. This substance has certain chemical activity and should be placed in a cool, dry and well-ventilated place. Because of the cool place, it can avoid the chemical reaction caused by excessive temperature and cause danger. In a dry environment, it is to prevent hydrolysis and other reactions in contact with water, which will damage its quality. Well-ventilated, it can disperse harmful gases that may escape in time and keep the storage environment safe. And it should be stored separately from oxidants, acids, alkalis, etc. These substances can chemically react with (1-chloroethyl) benzene and are prone to disasters. At the same time, the storage area should be equipped with suitable materials to contain the leakage, so as to prevent the accident and respond in time to prevent the leakage from spreading and causing greater harm.
As for transportation. The transportation vehicle must ensure that the vehicle is in good condition and has a reliable anti-leakage device. During driving, the driver should drive carefully to avoid bumps and sudden braking, so as to avoid the leakage of (1-chloroethyl) benzene caused by damage to the container. During transportation, it should be driven according to the specified route, away from densely populated areas and important places, such as schools, hospitals, residential areas, etc., to reduce the harm that may be caused in the event of an accident. The loading and unloading process must also be careful. The operator should be in front of suitable protective equipment, load and unload lightly, and strictly prohibit bumping and heavy pressure to ensure the
In this way, the storage and transportation of (1-chloroethyl) benzene should be done with caution in all aspects to ensure safety.
First word storage. This substance has certain chemical activity and should be placed in a cool, dry and well-ventilated place. Because of the cool place, it can avoid the chemical reaction caused by excessive temperature and cause danger. In a dry environment, it is to prevent hydrolysis and other reactions in contact with water, which will damage its quality. Well-ventilated, it can disperse harmful gases that may escape in time and keep the storage environment safe. And it should be stored separately from oxidants, acids, alkalis, etc. These substances can chemically react with (1-chloroethyl) benzene and are prone to disasters. At the same time, the storage area should be equipped with suitable materials to contain the leakage, so as to prevent the accident and respond in time to prevent the leakage from spreading and causing greater harm.
As for transportation. The transportation vehicle must ensure that the vehicle is in good condition and has a reliable anti-leakage device. During driving, the driver should drive carefully to avoid bumps and sudden braking, so as to avoid the leakage of (1-chloroethyl) benzene caused by damage to the container. During transportation, it should be driven according to the specified route, away from densely populated areas and important places, such as schools, hospitals, residential areas, etc., to reduce the harm that may be caused in the event of an accident. The loading and unloading process must also be careful. The operator should be in front of suitable protective equipment, load and unload lightly, and strictly prohibit bumping and heavy pressure to ensure the
In this way, the storage and transportation of (1-chloroethyl) benzene should be done with caution in all aspects to ensure safety.
What are the effects of (1-chloroethyl) benzene on the environment and human health?
(1-Chloroethyl) benzene is an organic compound. The impact of this substance on the environment and human health cannot be ignored.
At one end of the environment, (1-chloroethyl) benzene is volatile, escapes into the atmosphere, or participates in photochemical reactions, generating secondary pollutants such as ozone, resulting in a decline in air quality. And if it flows into water and soil, it is difficult to degrade, or remains in the environment for a long time, and it is tired in the living body. It is transmitted and amplified through the food chain, endangering the balance of the ecosystem, and has potential harm to aquatic organisms and soil microorganisms.
As for human health, (1-chloroethyl) benzene can enter the body through respiratory tract, skin contact, and accidental ingestion. It has the effect of irritating the mucosa of the eyes and respiratory tract. If inhaled, it will cause cough, sore throat, breathing difficulties in mild cases, and damage lung function in severe cases. Through skin contact, it can cause redness, swelling, itching, and burning of the skin. If eaten by mistake, it may hurt the stomach and cause nausea, vomiting, abdominal pain, etc. And this product may be potentially carcinogenic. Long-term exposure increases the risk of cancer, such as blood system diseases such as leukemia, and the possibility of cancer in organs such as liver and kidney.
In summary, (1-chloroethyl) benzene has adverse effects on the environment and human health. It should be treated with caution and properly controlled to reduce its harm.
At one end of the environment, (1-chloroethyl) benzene is volatile, escapes into the atmosphere, or participates in photochemical reactions, generating secondary pollutants such as ozone, resulting in a decline in air quality. And if it flows into water and soil, it is difficult to degrade, or remains in the environment for a long time, and it is tired in the living body. It is transmitted and amplified through the food chain, endangering the balance of the ecosystem, and has potential harm to aquatic organisms and soil microorganisms.
As for human health, (1-chloroethyl) benzene can enter the body through respiratory tract, skin contact, and accidental ingestion. It has the effect of irritating the mucosa of the eyes and respiratory tract. If inhaled, it will cause cough, sore throat, breathing difficulties in mild cases, and damage lung function in severe cases. Through skin contact, it can cause redness, swelling, itching, and burning of the skin. If eaten by mistake, it may hurt the stomach and cause nausea, vomiting, abdominal pain, etc. And this product may be potentially carcinogenic. Long-term exposure increases the risk of cancer, such as blood system diseases such as leukemia, and the possibility of cancer in organs such as liver and kidney.
In summary, (1-chloroethyl) benzene has adverse effects on the environment and human health. It should be treated with caution and properly controlled to reduce its harm.
What are the chemical properties of (1-chloroethyl) benzene?
(1-Chloroethyl) benzene, its chemical properties are quite unique. This is an organic compound. The stability of the benzene ring and the activity of the chloroethyl group are intertwined, resulting in a variety of chemical behaviors.
First, because it contains chloroethyl, it is active in nucleophilic substitution reactions. Nucleophilic reagents, such as alkoxides and amines, can attack the carbon atoms attached to the chlorine atoms, causing the chlorine atoms to leave and form new organic compounds. For example, when reacted with sodium alcohol, the chlorine atoms are replaced by alkoxy groups to form ether compounds. This reaction follows the nucleophilic substitution mechanism and is of great significance for the organic synthesis of ether substances.
Second, the benzene ring in this compound can undergo a typical aromatic electrophilic substitution reaction. Due to the electron-rich properties of the benzene ring, it is vulnerable to attack by electrophilic reagents. For example, under the catalysis of Lewis acid, reacting with a halogenating agent can introduce halogen atoms on the benzene ring; reacting with an acylating agent can realize the acylation of the benzene ring and generate aromatic ketones.
Furthermore, the chloroethyl part of (1-chloroethyl) benzene can be eliminated under specific conditions. For example, under the action of a strong base, the chlorine atom is removed from the hydrogen atom on the adjacent carbon atom to form a carbon-carbon double bond to produce styrene derivatives. This reaction provides a way to prepare aromatic compounds containing double bonds.
In addition, due to the large electronegativity of chlorine atoms, the distribution of electron clouds in the benzene ring is affected, which changes the electron cloud density at different positions on the benzene ring, which in turn affects the regioselectivity of electrophilic substitution reactions. The electron cloud density of the ortho and para-position is relatively high, and electrophilic reagents tend to attack these two positions more.
(1-chloroethyl) phenyl structure characteristics, it is widely used in the field of organic synthesis, and can be converted into various organic compounds through various reactions, laying the foundation for the development of materials science, pharmaceutical chemistry and other fields.
First, because it contains chloroethyl, it is active in nucleophilic substitution reactions. Nucleophilic reagents, such as alkoxides and amines, can attack the carbon atoms attached to the chlorine atoms, causing the chlorine atoms to leave and form new organic compounds. For example, when reacted with sodium alcohol, the chlorine atoms are replaced by alkoxy groups to form ether compounds. This reaction follows the nucleophilic substitution mechanism and is of great significance for the organic synthesis of ether substances.
Second, the benzene ring in this compound can undergo a typical aromatic electrophilic substitution reaction. Due to the electron-rich properties of the benzene ring, it is vulnerable to attack by electrophilic reagents. For example, under the catalysis of Lewis acid, reacting with a halogenating agent can introduce halogen atoms on the benzene ring; reacting with an acylating agent can realize the acylation of the benzene ring and generate aromatic ketones.
Furthermore, the chloroethyl part of (1-chloroethyl) benzene can be eliminated under specific conditions. For example, under the action of a strong base, the chlorine atom is removed from the hydrogen atom on the adjacent carbon atom to form a carbon-carbon double bond to produce styrene derivatives. This reaction provides a way to prepare aromatic compounds containing double bonds.
In addition, due to the large electronegativity of chlorine atoms, the distribution of electron clouds in the benzene ring is affected, which changes the electron cloud density at different positions on the benzene ring, which in turn affects the regioselectivity of electrophilic substitution reactions. The electron cloud density of the ortho and para-position is relatively high, and electrophilic reagents tend to attack these two positions more.
(1-chloroethyl) phenyl structure characteristics, it is widely used in the field of organic synthesis, and can be converted into various organic compounds through various reactions, laying the foundation for the development of materials science, pharmaceutical chemistry and other fields.
What are the physical properties of (1-chloroethyl) benzene?
(1-Chloroethyl) benzene is an organic compound. Its physical properties are unique and have the following characteristics.
Under normal temperature and pressure, (1-chloroethyl) benzene is colorless to light yellow liquid, clear and has a special smell. Its smell is unusual, pungent, and can cause certain stimulation to the human sense of smell.
When it comes to boiling point, it is about 179-184 ° C. This boiling point value shows that in order to convert it from liquid to gas, corresponding heat needs to be applied. This property is crucial in chemical operations such as distillation and separation.
As for the melting point, it is about -39 ° C. Under this temperature, (1-chloroethyl) benzene will solidify from liquid to solid. The melting point also affects its storage and transportation conditions.
(1-chloroethyl) benzene has a higher density than water, about 1.07 g/cm ³. Therefore, if it is mixed with water, it will sink underwater.
In terms of solubility, (1-chloroethyl) benzene is insoluble in water, but soluble in many organic solvents, such as ethanol, ether, benzene, etc. This solubility characteristic makes it often selected as a solvent in organic synthesis reactions to promote the progress of the reaction.
In addition, (1-chloroethyl) benzene is moderately volatile. Although it is not as volatile as some low-boiling substances, it will slowly evaporate into the air in an open environment. This volatile characteristic requires attention during use and storage to ensure safety and the environment are not affected.
Under normal temperature and pressure, (1-chloroethyl) benzene is colorless to light yellow liquid, clear and has a special smell. Its smell is unusual, pungent, and can cause certain stimulation to the human sense of smell.
When it comes to boiling point, it is about 179-184 ° C. This boiling point value shows that in order to convert it from liquid to gas, corresponding heat needs to be applied. This property is crucial in chemical operations such as distillation and separation.
As for the melting point, it is about -39 ° C. Under this temperature, (1-chloroethyl) benzene will solidify from liquid to solid. The melting point also affects its storage and transportation conditions.
(1-chloroethyl) benzene has a higher density than water, about 1.07 g/cm ³. Therefore, if it is mixed with water, it will sink underwater.
In terms of solubility, (1-chloroethyl) benzene is insoluble in water, but soluble in many organic solvents, such as ethanol, ether, benzene, etc. This solubility characteristic makes it often selected as a solvent in organic synthesis reactions to promote the progress of the reaction.
In addition, (1-chloroethyl) benzene is moderately volatile. Although it is not as volatile as some low-boiling substances, it will slowly evaporate into the air in an open environment. This volatile characteristic requires attention during use and storage to ensure safety and the environment are not affected.
What are the industrial applications of (1-chloroethyl) benzene?
(1-Chloroethyl) benzene is widely used in industry. It can be used as a raw material for organic synthesis, and is often used as a starting material when preparing a variety of fine chemicals. If you want to make specific pharmaceutical intermediates, (1-chloroethyl) benzene can be converted into the required structural fragments through ingenious chemical reactions, which can be used in the pharmaceutical industry to assist in the development and production of new drugs.
It is also useful in the field of materials science. Or it can participate in the synthesis of polymer materials. After polymerization, it can be combined with other monomers to give the material unique properties, such as improving the heat resistance and mechanical strength of the material, which contributes to the creation of new materials.
Furthermore, in the fragrance industry, (1-chloroethyl) benzene or through series transformation, compounds with special aroma are obtained, which are used to prepare various flavors, increase the rich level of flavors, and make them used in cosmetics, food and other industries to improve the olfactory experience of products.
In the field of pesticides, (1-chloroethyl) benzene can be used as a key raw material for the synthesis of pesticide active ingredients. Through rational molecular design and reaction, pesticides with efficient killing or inhibitory effects on pests can be created to ensure the healthy growth of crops and protect the harvest of agriculture. Therefore, (1-chloroethyl) benzene has important applications in many fields of industry, and is also an important chemical substance for promoting industrial development.
It is also useful in the field of materials science. Or it can participate in the synthesis of polymer materials. After polymerization, it can be combined with other monomers to give the material unique properties, such as improving the heat resistance and mechanical strength of the material, which contributes to the creation of new materials.
Furthermore, in the fragrance industry, (1-chloroethyl) benzene or through series transformation, compounds with special aroma are obtained, which are used to prepare various flavors, increase the rich level of flavors, and make them used in cosmetics, food and other industries to improve the olfactory experience of products.
In the field of pesticides, (1-chloroethyl) benzene can be used as a key raw material for the synthesis of pesticide active ingredients. Through rational molecular design and reaction, pesticides with efficient killing or inhibitory effects on pests can be created to ensure the healthy growth of crops and protect the harvest of agriculture. Therefore, (1-chloroethyl) benzene has important applications in many fields of industry, and is also an important chemical substance for promoting industrial development.
What are the synthesis methods of (1-chloroethyl) benzene?
There are many ways to synthesize (1-chloroethyl) benzene. One is to use benzene and chloroethane as raw materials, and under the catalysis of Lewis acid such as aluminum trichloride, the alkylation reaction is carried out. In this reaction, the chloroethane is affected by Lewis acid to generate carbon positive ions, which are electrophilic and can attack the electron cloud of the benzene ring, causing the benzene ring to be alkylated, and then obtain (1-chloroethyl) benzene.
There is also a method of adding styrene and hydrogen chloride. The carbon-carbon double bond of styrene is active. When encountering hydrogen chloride, according to the Markov rule, hydrogen atoms are added to the double-bonded carbon atoms with more hydrogen, and chlorine atoms are added to those with less hydrogen, so (1-chloroethyl) benzene can also be synthesized.
Then a halogen exchange reaction is carried out with (1-bromoethyl) benzene and halides such as lithium chloride. (1-bromoethyl) benzene has a high activity of bromine atoms, which can be exchanged with chloride ions of lithium chloride, and the final product (1-chloroethyl) benzene is obtained.
Synthesis methods have their own advantages and disadvantages. The raw materials for the Fu-gram alkylation reaction are easily available, but the reaction conditions may be more severe, and the product or isomer is formed; the addition of styrene and hydrogen chloride is relatively simple, so it is necessary to pay attention to the control of the reaction conditions to obtain a higher yield; although the halogen exchange reaction can accurately obtain the target product, the preparation of the raw material (1-bromoethyl) benzene may also require trouble.
There is also a method of adding styrene and hydrogen chloride. The carbon-carbon double bond of styrene is active. When encountering hydrogen chloride, according to the Markov rule, hydrogen atoms are added to the double-bonded carbon atoms with more hydrogen, and chlorine atoms are added to those with less hydrogen, so (1-chloroethyl) benzene can also be synthesized.
Then a halogen exchange reaction is carried out with (1-bromoethyl) benzene and halides such as lithium chloride. (1-bromoethyl) benzene has a high activity of bromine atoms, which can be exchanged with chloride ions of lithium chloride, and the final product (1-chloroethyl) benzene is obtained.
Synthesis methods have their own advantages and disadvantages. The raw materials for the Fu-gram alkylation reaction are easily available, but the reaction conditions may be more severe, and the product or isomer is formed; the addition of styrene and hydrogen chloride is relatively simple, so it is necessary to pay attention to the control of the reaction conditions to obtain a higher yield; although the halogen exchange reaction can accurately obtain the target product, the preparation of the raw material (1-bromoethyl) benzene may also require trouble.
What are the effects of (1-chloroethyl) benzene on the environment and human health?
(1-Chloroethyl) benzene is also a kind of chemical. It has a great impact on the environment and human health.
First talk about its harm to the environment. (1-Chloroethyl) benzene is volatile, and if it escapes in the atmosphere, it can cause air pollution. It enters the atmosphere, or reacts with other substances, generating harmful new pollutants, damaging air quality, and harming organisms. If it enters the water body, it is insoluble in water, or attached to suspended particles, sinks to the bottom of the water, and is tired of aquatic organisms. It is passed on through the food chain, causing increasing harm. And its existence in the water body, or inhibits the growth and reproduction of aquatic organisms, disrupting the ecological balance. If it enters the soil, it can accumulate in the soil, injure the activity of soil microorganisms, hinder the absorption of nutrients by plants, cause poor plant growth, and then affect the terrestrial ecosystem.
Second, its danger to human health. If people ingest (1-chloroethyl) benzene through breathing, skin contact or diet, it can be harmful. Inhalation through the respiratory tract can stab the mucosa of the respiratory tract, causing cough, asthma and other diseases. Long-term inhalation, or damage to the nervous system, causing dizziness, headache, fatigue, and even memory loss. If exposed through skin, it can cause skin allergies, itching, redness and swelling. And it is potentially carcinogenic, touching or inhaling it for a long time, or increasing the risk of cancer, such as leukemia. Dietary intake may harm the human digestive system, causing nausea, vomiting, and abdominal pain.
(1-chloroethyl) benzene is very harmful to the environment and human health. It is necessary to take precautions and reduce its emissions and exposure to protect the environment and human health.
First talk about its harm to the environment. (1-Chloroethyl) benzene is volatile, and if it escapes in the atmosphere, it can cause air pollution. It enters the atmosphere, or reacts with other substances, generating harmful new pollutants, damaging air quality, and harming organisms. If it enters the water body, it is insoluble in water, or attached to suspended particles, sinks to the bottom of the water, and is tired of aquatic organisms. It is passed on through the food chain, causing increasing harm. And its existence in the water body, or inhibits the growth and reproduction of aquatic organisms, disrupting the ecological balance. If it enters the soil, it can accumulate in the soil, injure the activity of soil microorganisms, hinder the absorption of nutrients by plants, cause poor plant growth, and then affect the terrestrial ecosystem.
Second, its danger to human health. If people ingest (1-chloroethyl) benzene through breathing, skin contact or diet, it can be harmful. Inhalation through the respiratory tract can stab the mucosa of the respiratory tract, causing cough, asthma and other diseases. Long-term inhalation, or damage to the nervous system, causing dizziness, headache, fatigue, and even memory loss. If exposed through skin, it can cause skin allergies, itching, redness and swelling. And it is potentially carcinogenic, touching or inhaling it for a long time, or increasing the risk of cancer, such as leukemia. Dietary intake may harm the human digestive system, causing nausea, vomiting, and abdominal pain.
(1-chloroethyl) benzene is very harmful to the environment and human health. It is necessary to take precautions and reduce its emissions and exposure to protect the environment and human health.
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