Linshang Chemical
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1-Chloromethyl-2,3,4,5,6-Pentafluoro-Benzene
Linshang Chemical
|
HS Code |
330744 |
| Chemical Formula | C7H2ClF5 |
| Molecular Weight | 228.535 |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Around 130 - 132 °C |
| Density | Approx. 1.56 g/cm³ |
| Vapor Pressure | Low at room temperature |
| Solubility | Insoluble in water, soluble in organic solvents like ether, chloroform |
| Flash Point | Ca. 43 °C |
| Stability | Stable under normal conditions, but reactive with strong oxidizing agents |
| Odor | Characteristic, pungent odor |
As an accredited 1-Chloromethyl-2,3,4,5,6-Pentafluoro-Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle of 1 - chloromethyl - 2,3,4,5,6 - pentafluoro - benzene, well - sealed. |
| Storage | 1 - Chloromethyl - 2,3,4,5,6 - pentafluoro - benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly - sealed container, preferably made of corrosion - resistant materials. Separate storage from oxidizing agents and reactive chemicals to prevent potential chemical reactions. Ensure proper labeling for easy identification. |
| Shipping | 1 - Chloromethyl - 2,3,4,5,6 - pentafluoro - benzene, a chemical, must be shipped in accordance with strict hazardous materials regulations. Use specialized containers, ensure proper labeling, and transport via carriers licensed for such chemicals. |
Competitive 1-Chloromethyl-2,3,4,5,6-Pentafluoro-Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 1-Chloromethyl-2,3,4,5,6-Pentafluoro-Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1-chloromethyl-2,3,4,5,6-pentafluorobenzene?
The physical properties of 5-bromo-2,3,4,5,6-pentafluorobenzyl group are special.
First of all, its external properties are usually solid, which is due to the action of the molecule. It holds a solid shape under normal conditions. Its melting, due to the dense order of the molecule and the characteristics of fluorine and bromine atoms, causes it to melt in a certain degree.
Furthermore, in terms of solubility, because the molecule contains polyfluorine atoms, the high solubility of fluorine atoms makes the molecule have a certain degree of solubility. However, it also contains aromatics, resulting in different solubility in soluble and non-soluble molecules. In alcohols, such as alcohols, because some of their properties can interact with the alkyl groups of alcohols, they have a certain solubility; in non-soluble solutions, such as alkanes, because their aromatic parts can interact weakly, they also have a certain solubility, but in terms of solubility, the degree of solubility is limited.
The density of
is due to the large atomic weight of fluorine and bromine atoms, and the molecular weight is low, so the density of the phase is high, and the general compound is high.
In addition, its characterization is also worth mentioning. The formation of polyfluorine atoms in the molecule results in high energy, and the co-effect of benzene makes the compound have good chemical properties under certain conditions. However, in case of specific conditions such as oxidation and prototyping, it can also improve its biochemical properties and physical properties.
First of all, its external properties are usually solid, which is due to the action of the molecule. It holds a solid shape under normal conditions. Its melting, due to the dense order of the molecule and the characteristics of fluorine and bromine atoms, causes it to melt in a certain degree.
Furthermore, in terms of solubility, because the molecule contains polyfluorine atoms, the high solubility of fluorine atoms makes the molecule have a certain degree of solubility. However, it also contains aromatics, resulting in different solubility in soluble and non-soluble molecules. In alcohols, such as alcohols, because some of their properties can interact with the alkyl groups of alcohols, they have a certain solubility; in non-soluble solutions, such as alkanes, because their aromatic parts can interact weakly, they also have a certain solubility, but in terms of solubility, the degree of solubility is limited.
The density of
is due to the large atomic weight of fluorine and bromine atoms, and the molecular weight is low, so the density of the phase is high, and the general compound is high.
In addition, its characterization is also worth mentioning. The formation of polyfluorine atoms in the molecule results in high energy, and the co-effect of benzene makes the compound have good chemical properties under certain conditions. However, in case of specific conditions such as oxidation and prototyping, it can also improve its biochemical properties and physical properties.
What are the chemical properties of 1-chloromethyl-2,3,4,5,6-pentafluorobenzene?
5-Bromo-2,3,4,5,6-pentafluoroanisole is an organic compound with specific chemical properties. Its properties are as follows:
1. ** Physical properties **: Under normal conditions, this substance may be a colorless to light yellow liquid, which is liquid at room temperature and has certain volatility. Due to the presence of fluorine, bromine and other halogen atoms, its boiling point, melting point and other physical constants are affected by the type and number of atoms. Fluorine-containing organic compounds often have hot topic stability and chemical stability, 5-bromo-2,3,4,5,6-pentafluoroanisole or have similar properties, and can maintain a stable structure in high temperature environments.
2. ** Chemical Properties **:
- ** Nucleophilic Substitution Reaction **: The bromine atom in the molecule has high activity and is vulnerable to attack by nucleophilic reagents, resulting in a nucleophilic substitution reaction. Nucleophilic reagents such as sodium alcohol and amines can interact with bromine atoms, so that bromine atoms are replaced by other groups to form new organic compounds. For example, sodium alcohol reacts with it, and bromine atoms can be replaced by alkoxy groups to form new ether compounds. This reaction is often used in organic synthesis to construct carbon-heteroatom bonds.
- ** Aroma-related reactions **: The compound contains a benzene ring structure and has aromatic properties. Although multiple hydrogen atoms on the benzene ring are replaced by fluorine atoms, their aromatics still enable the benzene ring to undergo electrophilic substitution reactions. Electrophilic reagents such as bromination reaction catalyzed by ferric bromide, or nitration reaction under the action of concentrated sulfuric acid and concentrated nitric acid mixed acid, etc. However, due to the electron-withdrawing effect of fluorine atoms, the electron cloud density of benzene ring decreases, and the electrophilic substitution reaction activity decreases compared with benzene.
- ** Fluorine atomic characteristics **: Multiple fluorine atoms in the molecule endow it with unique properties. Fluorine atoms have high electronegativity, which can enhance molecular polarity and affect their solubility and reactivity. And the C-F bond energy is large, which increases the stability of the molecule. Under some conditions, the fluorine-containing part is difficult to break, and specific reagents and conditions are required to react.
3. ** Stability **: In view of the structure of fluorine atoms and phenyl rings, 5-bromo-2,3,4,5,6-pentafluoroanisole is relatively stable, and it is not easy to spontaneously decompose or react violently under general environmental and common chemical reaction conditions. However, in case of strong oxidants, reducing agents or specific high temperatures, high pressures and catalysts, corresponding chemical changes can still occur.
1. ** Physical properties **: Under normal conditions, this substance may be a colorless to light yellow liquid, which is liquid at room temperature and has certain volatility. Due to the presence of fluorine, bromine and other halogen atoms, its boiling point, melting point and other physical constants are affected by the type and number of atoms. Fluorine-containing organic compounds often have hot topic stability and chemical stability, 5-bromo-2,3,4,5,6-pentafluoroanisole or have similar properties, and can maintain a stable structure in high temperature environments.
2. ** Chemical Properties **:
- ** Nucleophilic Substitution Reaction **: The bromine atom in the molecule has high activity and is vulnerable to attack by nucleophilic reagents, resulting in a nucleophilic substitution reaction. Nucleophilic reagents such as sodium alcohol and amines can interact with bromine atoms, so that bromine atoms are replaced by other groups to form new organic compounds. For example, sodium alcohol reacts with it, and bromine atoms can be replaced by alkoxy groups to form new ether compounds. This reaction is often used in organic synthesis to construct carbon-heteroatom bonds.
- ** Aroma-related reactions **: The compound contains a benzene ring structure and has aromatic properties. Although multiple hydrogen atoms on the benzene ring are replaced by fluorine atoms, their aromatics still enable the benzene ring to undergo electrophilic substitution reactions. Electrophilic reagents such as bromination reaction catalyzed by ferric bromide, or nitration reaction under the action of concentrated sulfuric acid and concentrated nitric acid mixed acid, etc. However, due to the electron-withdrawing effect of fluorine atoms, the electron cloud density of benzene ring decreases, and the electrophilic substitution reaction activity decreases compared with benzene.
- ** Fluorine atomic characteristics **: Multiple fluorine atoms in the molecule endow it with unique properties. Fluorine atoms have high electronegativity, which can enhance molecular polarity and affect their solubility and reactivity. And the C-F bond energy is large, which increases the stability of the molecule. Under some conditions, the fluorine-containing part is difficult to break, and specific reagents and conditions are required to react.
3. ** Stability **: In view of the structure of fluorine atoms and phenyl rings, 5-bromo-2,3,4,5,6-pentafluoroanisole is relatively stable, and it is not easy to spontaneously decompose or react violently under general environmental and common chemical reaction conditions. However, in case of strong oxidants, reducing agents or specific high temperatures, high pressures and catalysts, corresponding chemical changes can still occur.
What are the main uses of 1-chloromethyl-2,3,4,5,6-pentafluorobenzene?
The main use of pentabromobenzyl-2,3,4,5,6-pentabromobenzene is not limited to one end, and it is related to the function of many fields.
In the category of flame retardant materials, this substance is a key flame retardant. Because it is rich in bromine, bromine can play a significant flame retardant effect during combustion. When the material is exposed to fire, pentabromobenzyl-2,3,4,5,6-pentabromobenzene is thermally decomposed, releasing bromine-containing free radicals. This free radical can interact with the active free radical produced by combustion to quench the chain combustion reaction, thereby effectively inhibiting the spread of fire and greatly improving the flame retardant performance of the material. Therefore, many plastic products, fiber fabrics, and electronic and electrical components are often added to meet flame retardant standards to protect personal and property safety and prevent fire.
Furthermore, in the field of polymer material modification, it also plays an important role. It can be introduced into the structure of polymer by chemical methods, so that it can not only give the polymer material excellent flame retardancy, but also improve its mechanical properties and thermal stability. For example, adding an appropriate amount of pentabromobenzyl-2,3,4,5,6-pentabromobenzene to some engineering plastics can increase the thermal deformation temperature of plastics, enhance their dimensional stability in high temperature environments, and do not damage their original processing properties and mechanical strength, broaden the application range of polymer materials, so that they can be used in aerospace, automobile manufacturing and other fields that require strict material properties.
In addition, in the field of organic synthetic chemistry, pentabromobenzyl-2,3,4,5,6-pentabromobenzene can be used as an important intermediate. With its unique molecular structure and reactivity, chemists can transform it into other organic compounds with specific functions through various chemical reactions, such as materials with special photoelectric properties, bioactive molecules, etc., to open up new paths for the development of organic synthetic chemistry and help scientists create more novel and practical compounds.
In the category of flame retardant materials, this substance is a key flame retardant. Because it is rich in bromine, bromine can play a significant flame retardant effect during combustion. When the material is exposed to fire, pentabromobenzyl-2,3,4,5,6-pentabromobenzene is thermally decomposed, releasing bromine-containing free radicals. This free radical can interact with the active free radical produced by combustion to quench the chain combustion reaction, thereby effectively inhibiting the spread of fire and greatly improving the flame retardant performance of the material. Therefore, many plastic products, fiber fabrics, and electronic and electrical components are often added to meet flame retardant standards to protect personal and property safety and prevent fire.
Furthermore, in the field of polymer material modification, it also plays an important role. It can be introduced into the structure of polymer by chemical methods, so that it can not only give the polymer material excellent flame retardancy, but also improve its mechanical properties and thermal stability. For example, adding an appropriate amount of pentabromobenzyl-2,3,4,5,6-pentabromobenzene to some engineering plastics can increase the thermal deformation temperature of plastics, enhance their dimensional stability in high temperature environments, and do not damage their original processing properties and mechanical strength, broaden the application range of polymer materials, so that they can be used in aerospace, automobile manufacturing and other fields that require strict material properties.
In addition, in the field of organic synthetic chemistry, pentabromobenzyl-2,3,4,5,6-pentabromobenzene can be used as an important intermediate. With its unique molecular structure and reactivity, chemists can transform it into other organic compounds with specific functions through various chemical reactions, such as materials with special photoelectric properties, bioactive molecules, etc., to open up new paths for the development of organic synthetic chemistry and help scientists create more novel and practical compounds.
What are the synthesis methods of 1-chloromethyl-2,3,4,5,6-pentafluorobenzene?
To prepare 5-bromo-2,3,4,5,6-pentafluoroanisole, the following synthesis methods can be used:
First, fluorobenzene-containing compounds are used as starting materials. The fluorobenzene is halogenated in a shilling, and bromine atoms are introduced at a specific position. This halogenation reaction requires careful selection of halogenating reagents and reaction conditions. If a suitable brominating agent is selected, the bromine atoms are precisely placed at the expected position in the presence of a catalyst and the temperature and solvent are suitable. Subsequently, methoxylation is carried out. Select a suitable methoxylation reagent, such as sodium methoxide, and in a suitable reaction environment, urge the methoxyl group to replace other atoms or groups on the benzene ring, and finally obtain the target product 5-bromo-2,3,4,5,6-pentafluoroanisole. The key to this path lies in the control of the reaction conditions of the halogenation and methoxylation steps, so that the reaction is efficient and selective.
Second, start from bromobenzene. First fluorinate the benzene ring and introduce fluorine atoms. The fluorination reaction usually requires the help of specific fluorination reagents, such as Selectfluor. In this process, the optimization of reaction conditions, including temperature, reaction time, and the proportion of reactants, is extremely important to ensure that fluorine atoms are introduced into the benzene ring one by one according to the design requirements. Then, the methoxylation operation is carried out, and the methoxyl group is introduced with a suitable methoxylation reagent as described above, so as to synthesize the target product. The difficulty of this approach lies in the precise control of the fluorination reaction to avoid excessive fluorination or the position deviation of the fluorine atom introduction.
Third, the strategy of gradually constructing the benzene ring can also be considered. First, a small molecule intermediate containing part of the fluorine atom and the bromine atom is prepared, and the benzene ring structure is gradually constructed through organic synthesis methods, such as nucleophilic substitution, coupling reaction, etc., and the methoxy group is introduced in a timely manner. For example, using the nucleophilic substitution reaction of halogenated aromatics and fluorine-containing nucleophiles, a fluorine-containing and bromine-containing benzene ring fragment is first constructed, and then methoxy groups are introduced through subsequent reactions to finally complete the synthesis of 5-bromo-2,3,4,5,6-pentafluoroanisole. This method requires a deep understanding of the mechanism and conditions of each step of the reaction to achieve accurate construction of complex structures.
First, fluorobenzene-containing compounds are used as starting materials. The fluorobenzene is halogenated in a shilling, and bromine atoms are introduced at a specific position. This halogenation reaction requires careful selection of halogenating reagents and reaction conditions. If a suitable brominating agent is selected, the bromine atoms are precisely placed at the expected position in the presence of a catalyst and the temperature and solvent are suitable. Subsequently, methoxylation is carried out. Select a suitable methoxylation reagent, such as sodium methoxide, and in a suitable reaction environment, urge the methoxyl group to replace other atoms or groups on the benzene ring, and finally obtain the target product 5-bromo-2,3,4,5,6-pentafluoroanisole. The key to this path lies in the control of the reaction conditions of the halogenation and methoxylation steps, so that the reaction is efficient and selective.
Second, start from bromobenzene. First fluorinate the benzene ring and introduce fluorine atoms. The fluorination reaction usually requires the help of specific fluorination reagents, such as Selectfluor. In this process, the optimization of reaction conditions, including temperature, reaction time, and the proportion of reactants, is extremely important to ensure that fluorine atoms are introduced into the benzene ring one by one according to the design requirements. Then, the methoxylation operation is carried out, and the methoxyl group is introduced with a suitable methoxylation reagent as described above, so as to synthesize the target product. The difficulty of this approach lies in the precise control of the fluorination reaction to avoid excessive fluorination or the position deviation of the fluorine atom introduction.
Third, the strategy of gradually constructing the benzene ring can also be considered. First, a small molecule intermediate containing part of the fluorine atom and the bromine atom is prepared, and the benzene ring structure is gradually constructed through organic synthesis methods, such as nucleophilic substitution, coupling reaction, etc., and the methoxy group is introduced in a timely manner. For example, using the nucleophilic substitution reaction of halogenated aromatics and fluorine-containing nucleophiles, a fluorine-containing and bromine-containing benzene ring fragment is first constructed, and then methoxy groups are introduced through subsequent reactions to finally complete the synthesis of 5-bromo-2,3,4,5,6-pentafluoroanisole. This method requires a deep understanding of the mechanism and conditions of each step of the reaction to achieve accurate construction of complex structures.
What are the precautions for storing and transporting 1-chloromethyl-2,3,4,5,6-pentafluorobenzene?
The pentabromobenzene of halomethyl group should be paid attention to when storing and transporting it.
First, it is chemically active, and the halomethyl functional group is active, which is easy to react with other substances. Therefore, when storing, it must be avoided from coexisting with nucleophiles and basic substances. In case of nucleophiles, halomethyl groups may be replaced, resulting in impure products; in alkaline substances, it may also initiate elimination reactions, damaging its structure and properties.
Second, there are many bromine atoms in pentabromobenzene, and its stability may be affected. High temperature, light and other conditions can cause bromine atoms to detach, trigger free radical reactions, or cause compounds to decompose and deteriorate. It is suitable for storage in a cool and dark place. It should also be protected from direct sunlight and high temperature environments during transportation.
Furthermore, halomethylpentabromobenzene may be toxic and corrosive. When in contact, be sure to follow safety procedures. The operator wears protective clothing, gloves, and goggles to prevent it from coming into contact with the skin and eyes. If you accidentally touch it, rinse it with plenty of water as soon as possible and seek medical treatment.
Also, during transportation, the packaging must be strong and tight to prevent leakage. Once a leak occurs, it will not only damage the goods, but also pollute the environment and endanger the surrounding organisms. If a leak occurs, it should be dealt with according to the emergency plan, containment and cleaning to prevent the spread.
In conclusion, when storing and transporting halomethyl-2,3,4,5,6-pentabromobenzene, pay attention to the chemical activity, stability, toxicity and packaging protection to ensure its safety and avoid the risk of accidents.
First, it is chemically active, and the halomethyl functional group is active, which is easy to react with other substances. Therefore, when storing, it must be avoided from coexisting with nucleophiles and basic substances. In case of nucleophiles, halomethyl groups may be replaced, resulting in impure products; in alkaline substances, it may also initiate elimination reactions, damaging its structure and properties.
Second, there are many bromine atoms in pentabromobenzene, and its stability may be affected. High temperature, light and other conditions can cause bromine atoms to detach, trigger free radical reactions, or cause compounds to decompose and deteriorate. It is suitable for storage in a cool and dark place. It should also be protected from direct sunlight and high temperature environments during transportation.
Furthermore, halomethylpentabromobenzene may be toxic and corrosive. When in contact, be sure to follow safety procedures. The operator wears protective clothing, gloves, and goggles to prevent it from coming into contact with the skin and eyes. If you accidentally touch it, rinse it with plenty of water as soon as possible and seek medical treatment.
Also, during transportation, the packaging must be strong and tight to prevent leakage. Once a leak occurs, it will not only damage the goods, but also pollute the environment and endanger the surrounding organisms. If a leak occurs, it should be dealt with according to the emergency plan, containment and cleaning to prevent the spread.
In conclusion, when storing and transporting halomethyl-2,3,4,5,6-pentabromobenzene, pay attention to the chemical activity, stability, toxicity and packaging protection to ensure its safety and avoid the risk of accidents.
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