Linshang Chemical
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1-(Chloromethyl)-2,3-Difluorobenzene
Linshang Chemical
|
HS Code |
575268 |
| Chemical Formula | C7H5ClF2 |
| Molecular Weight | 162.56 |
| Appearance | Liquid (usually) |
| Boiling Point | Data may vary, around 170 - 180 °C |
| Density | Typical range around 1.3 - 1.4 g/cm³ |
| Solubility In Water | Low solubility, immiscible |
| Solubility In Organic Solvents | Soluble in many organic solvents like dichloromethane, ethyl acetate |
| Vapor Pressure | Low vapor pressure at room temperature |
| Odor | Characteristic aromatic - halogenated odor |
As an accredited 1-(Chloromethyl)-2,3-Difluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1-(chloromethyl)-2,3 -difluorobenzene in a sealed, corrosion - resistant bottle. |
| Storage | 1-(Chloromethyl)-2,3 -difluorobenzene should be stored in a cool, well - ventilated area, away from heat, sparks, and open flames as it is likely flammable. Keep it in a tightly sealed container to prevent leakage and exposure to air or moisture, which could potentially cause reactions. Store it separately from oxidizing agents and incompatible substances to avoid hazardous interactions. |
| Shipping | 1-(Chloromethyl)-2,3 -difluorobenzene is shipped in specialized, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper handling, storage, and transportation to prevent spills and risks. |
Competitive 1-(Chloromethyl)-2,3-Difluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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As a leading 1-(Chloromethyl)-2,3-Difluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1- (chloromethyl) -2,3-difluorobenzene?
1 - (methoxy) -2,3 -dihydronaphthalene is a kind of organic compound. Its physical properties are quite characteristic, and I will describe them in detail for you.
Looking at its appearance, it is often colorless to light yellow liquid, with a clear and transparent texture. This form is easy to operate and handle in many organic synthesis scenarios. Its boiling point is a specific value, about [X] ° C. This boiling point characteristic allows it to be effectively separated from the mixture by distillation during the separation and purification process. Due to the different boiling points of different substances, at this temperature, 1- (methoxy) -2,3-dihydronaphthalene will be vaporized into steam, and then condensed into a liquid to achieve the purpose of separation.
The melting point is about [X] ° C, and this melting point value determines its physical state under a specific temperature environment. When the ambient temperature is below the melting point, the substance will solidify into a solid state; above the melting point, it will be a liquid state. This property needs to be taken into account during storage and transportation to ensure that it remains in a suitable state.
Furthermore, its density is also an important physical property, about [X] g/cm ³. This density value makes 1- (methoxy) -2,3-dihydronaphthalene stratified according to density differences when mixed with other liquids, which can provide a basis for chemical analysis and separation operations.
In terms of solubility, 1- (methoxy) -2,3-dihydronaphthalene has good solubility in organic solvents such as ethanol and ether, and can dissolve with it to form a uniform solution. However, the solubility in water is poor. Due to the molecular structure of the compound, it is an organic molecule, and the interaction force between it and water molecules is weak, so it is difficult to dissolve in water. This difference in solubility is of great significance in terms of extraction, reaction medium selection, etc., according to which suitable solvents can be selected to promote the progress of chemical reactions or achieve the goal of material separation.
Looking at its appearance, it is often colorless to light yellow liquid, with a clear and transparent texture. This form is easy to operate and handle in many organic synthesis scenarios. Its boiling point is a specific value, about [X] ° C. This boiling point characteristic allows it to be effectively separated from the mixture by distillation during the separation and purification process. Due to the different boiling points of different substances, at this temperature, 1- (methoxy) -2,3-dihydronaphthalene will be vaporized into steam, and then condensed into a liquid to achieve the purpose of separation.
The melting point is about [X] ° C, and this melting point value determines its physical state under a specific temperature environment. When the ambient temperature is below the melting point, the substance will solidify into a solid state; above the melting point, it will be a liquid state. This property needs to be taken into account during storage and transportation to ensure that it remains in a suitable state.
Furthermore, its density is also an important physical property, about [X] g/cm ³. This density value makes 1- (methoxy) -2,3-dihydronaphthalene stratified according to density differences when mixed with other liquids, which can provide a basis for chemical analysis and separation operations.
In terms of solubility, 1- (methoxy) -2,3-dihydronaphthalene has good solubility in organic solvents such as ethanol and ether, and can dissolve with it to form a uniform solution. However, the solubility in water is poor. Due to the molecular structure of the compound, it is an organic molecule, and the interaction force between it and water molecules is weak, so it is difficult to dissolve in water. This difference in solubility is of great significance in terms of extraction, reaction medium selection, etc., according to which suitable solvents can be selected to promote the progress of chemical reactions or achieve the goal of material separation.
What are the main uses of 1- (chloromethyl) -2,3-difluorobenzene?
1- (cyanomethyl) -2,3-dibromonaphthalene is an organic compound with a wide range of main uses.
In the field of organic synthesis, this compound acts as a key intermediate. For example, in the construction of complex polycyclic aromatic hydrocarbon systems, 1- (cyanomethyl) -2,3-dibromonaphthalene can skillfully introduce specific functional groups through a series of reaction steps such as nucleophilic substitution and cyclization with the help of cyanine and bromine atoms, so as to precisely construct the target molecular framework. For example, in the process of synthesizing some fused cyclic aromatic materials with special photoelectric properties, it can convert cyanyl groups into other functional groups by nucleophilic substitution reactions with various nucleophiles, thereby realizing effective regulation of the electronic structure and properties of the material.
In the field of pharmaceutical chemistry, this compound also has potential application value. Due to its unique chemical structure, it may be used as a lead compound to carry out structural modification and optimization. For example, by selectively substituting bromine atoms and introducing biologically active groups, it is very likely to develop new drug molecules with specific pharmacological activities. Studies have shown that some compounds containing naphthalene ring structure exhibit certain affinity and inhibitory activity to some disease targets. 1- (cyanomethyl) -2,3-dibromonaphthalene has the potential to be further developed as a drug for the treatment of specific diseases by virtue of its naphthalene ring and functional groups such as cyanomethyl and bromine atoms.
In addition, in the field of materials science, 1- (cyanomethyl) -2,3-dibromonaphthalene may be used to prepare functional materials. For example, when preparing polymer materials with special optical and electrical properties, it can be used as a monomer to participate in the polymerization reaction, giving the material unique properties. With the polarity of the cyanyl group and the electronic effect of the bromine atom, the intermolecular interaction and charge transport properties of the material can be influenced, and materials with special properties can be obtained to meet the specific needs of fields such as organic Light Emitting Diodes and field-effect transistors.
In the field of organic synthesis, this compound acts as a key intermediate. For example, in the construction of complex polycyclic aromatic hydrocarbon systems, 1- (cyanomethyl) -2,3-dibromonaphthalene can skillfully introduce specific functional groups through a series of reaction steps such as nucleophilic substitution and cyclization with the help of cyanine and bromine atoms, so as to precisely construct the target molecular framework. For example, in the process of synthesizing some fused cyclic aromatic materials with special photoelectric properties, it can convert cyanyl groups into other functional groups by nucleophilic substitution reactions with various nucleophiles, thereby realizing effective regulation of the electronic structure and properties of the material.
In the field of pharmaceutical chemistry, this compound also has potential application value. Due to its unique chemical structure, it may be used as a lead compound to carry out structural modification and optimization. For example, by selectively substituting bromine atoms and introducing biologically active groups, it is very likely to develop new drug molecules with specific pharmacological activities. Studies have shown that some compounds containing naphthalene ring structure exhibit certain affinity and inhibitory activity to some disease targets. 1- (cyanomethyl) -2,3-dibromonaphthalene has the potential to be further developed as a drug for the treatment of specific diseases by virtue of its naphthalene ring and functional groups such as cyanomethyl and bromine atoms.
In addition, in the field of materials science, 1- (cyanomethyl) -2,3-dibromonaphthalene may be used to prepare functional materials. For example, when preparing polymer materials with special optical and electrical properties, it can be used as a monomer to participate in the polymerization reaction, giving the material unique properties. With the polarity of the cyanyl group and the electronic effect of the bromine atom, the intermolecular interaction and charge transport properties of the material can be influenced, and materials with special properties can be obtained to meet the specific needs of fields such as organic Light Emitting Diodes and field-effect transistors.
What are the synthesis methods of 1- (chloromethyl) -2,3-difluorobenzene?
The synthesis of 1- (cyanomethyl) -2,3-dibrominated naphthalene is an important research topic in the field of organic synthetic chemistry. Its synthesis pathways are diverse, and the ancient method is based on the ancient method.
First, it can be prepared from naphthalene through a multi-step reaction. First, the naphthalene is reacted with a halogenated reagent under specific conditions to introduce halogen atoms to form a halogenated naphthalene derivative. This step requires careful control of the reaction temperature, time and reagent dosage to ensure that the reaction proceeds in the desired direction. Then, the halogenated naphthalene derivative undergoes a nucleophilic substitution reaction with the reagent containing cyanomethyl. The activity of the nucleophilic reagent and the choice of the reaction solvent all have a significant impact on the reaction yield. After these two steps, 1- (cyanomethyl) -2,3-dibromonaphthalene can be obtained.
Second, we can also start with compounds containing cyanomethyl and bromonaphthalene derivatives. First prepare suitable bromonaphthalene derivatives to ensure that the bromine atom is in a suitable position for the reaction. At the same time, carefully select the reagent containing cyanomethyl to ensure that it has sufficient reactivity. After that, the two condensation reactions occur in the presence of catalysts. Factors such as the type and dosage of catalysts, the pH of the reaction environment, etc. are all related to whether the reaction can proceed smoothly, as well as the purity and yield of the product.
Furthermore, there is a strategy to use a certain type of fused aromatic hydrocarbon as the starting material. First, the structure of the fused aromatic hydrocarbon is modified, and cyanomethyl and bromine atoms are introduced at suitable positions through a series of reactions. This process requires precise design of the reaction sequence, full consideration of the interaction between functional groups, avoidance of unnecessary side reactions, and gradual synthesis of 1- (cyanomethyl) -2,3-dibromonaphthalene.
There are many methods for synthesizing 1- (cyanomethyl) -2,3-dibromonaphthalene, and each method has its own advantages and disadvantages. In actual operation, it is necessary to consider the availability of raw materials, cost, difficulty in controlling reaction conditions, and the purity and yield of the product, and choose the most suitable synthesis path.
First, it can be prepared from naphthalene through a multi-step reaction. First, the naphthalene is reacted with a halogenated reagent under specific conditions to introduce halogen atoms to form a halogenated naphthalene derivative. This step requires careful control of the reaction temperature, time and reagent dosage to ensure that the reaction proceeds in the desired direction. Then, the halogenated naphthalene derivative undergoes a nucleophilic substitution reaction with the reagent containing cyanomethyl. The activity of the nucleophilic reagent and the choice of the reaction solvent all have a significant impact on the reaction yield. After these two steps, 1- (cyanomethyl) -2,3-dibromonaphthalene can be obtained.
Second, we can also start with compounds containing cyanomethyl and bromonaphthalene derivatives. First prepare suitable bromonaphthalene derivatives to ensure that the bromine atom is in a suitable position for the reaction. At the same time, carefully select the reagent containing cyanomethyl to ensure that it has sufficient reactivity. After that, the two condensation reactions occur in the presence of catalysts. Factors such as the type and dosage of catalysts, the pH of the reaction environment, etc. are all related to whether the reaction can proceed smoothly, as well as the purity and yield of the product.
Furthermore, there is a strategy to use a certain type of fused aromatic hydrocarbon as the starting material. First, the structure of the fused aromatic hydrocarbon is modified, and cyanomethyl and bromine atoms are introduced at suitable positions through a series of reactions. This process requires precise design of the reaction sequence, full consideration of the interaction between functional groups, avoidance of unnecessary side reactions, and gradual synthesis of 1- (cyanomethyl) -2,3-dibromonaphthalene.
There are many methods for synthesizing 1- (cyanomethyl) -2,3-dibromonaphthalene, and each method has its own advantages and disadvantages. In actual operation, it is necessary to consider the availability of raw materials, cost, difficulty in controlling reaction conditions, and the purity and yield of the product, and choose the most suitable synthesis path.
What are the precautions for 1- (chloromethyl) -2,3-difluorobenzene during storage and transportation?
(1) Precautions
1. Low temperature and oxidation
1 - (cyanomethyl) -2,3-dibromonaphthalene should be stored in low temperature and dryness. Due to its resistance or dampness, high temperature, its chemical properties can be changed, and the product can be damaged or dangerous. If the environment is damp, or it is caused to be hydrolyzed and other reactions, the original product can be changed; high temperature may promote its decomposition or accelerate the reaction, which is unfavorable for storage.
2. Fire source and oxidation
This compound has a certain chemical activity, and the fire source may cause combustion or even explosion. Oxidation can also cause strong reactions, because there are parts of the molecule that can be oxidized. For example, in the presence of oxidation, the base layer on the naphthalene or naphthalene layer may be oxidized, so the material properties can be changed, so it is necessary to maintain a safe distance between the ignition source and the oxidation layer.
3. Sealed storage
To prevent the connection of components such as oxygen and water vapor in the air, it is necessary to seal storage. Oxygen can cause slow oxidation, water vapor energy hydrolysis and other reactions. Sealed containers can be used in glass bottles or special plastic containers, and the containers need to be in good condition to ensure good sealing.
(2) Precautions
1. The package is firm
, and the package of 1- (cyanomethyl) -2,3-dibromonaphthalene must be firm and reliable. Due to its chemical composition, if the packaging is damaged, leakage may pollute the environment and endanger human safety. The packaging material has good anti-collision and anti-corrosion properties, such as the use of thick-walled glass bottles, wrapped in shock-proof materials, and placed in the solid outer box.
2. Clear
There must be a clear label outside the container, indicating that the contents of 1- (cyanomethyl) -2,3-dibromonaphthalene are clear, such as flammable, toxic and other phase warnings. In this way, human and phase workers can clearly understand its characteristics, and take positive prevention measures during the removal and release process.
3. Follow the standard
This compound must follow the phase chemical method. In the same way, if the highway needs to be applied for, it should be traveled according to the designated route; the aviation transportation must comply with the price restrictions of aviation transportation products. During the transportation, it is also necessary to regularly check whether the package is in good condition to prevent accidents.
1. Low temperature and oxidation
1 - (cyanomethyl) -2,3-dibromonaphthalene should be stored in low temperature and dryness. Due to its resistance or dampness, high temperature, its chemical properties can be changed, and the product can be damaged or dangerous. If the environment is damp, or it is caused to be hydrolyzed and other reactions, the original product can be changed; high temperature may promote its decomposition or accelerate the reaction, which is unfavorable for storage.
2. Fire source and oxidation
This compound has a certain chemical activity, and the fire source may cause combustion or even explosion. Oxidation can also cause strong reactions, because there are parts of the molecule that can be oxidized. For example, in the presence of oxidation, the base layer on the naphthalene or naphthalene layer may be oxidized, so the material properties can be changed, so it is necessary to maintain a safe distance between the ignition source and the oxidation layer.
3. Sealed storage
To prevent the connection of components such as oxygen and water vapor in the air, it is necessary to seal storage. Oxygen can cause slow oxidation, water vapor energy hydrolysis and other reactions. Sealed containers can be used in glass bottles or special plastic containers, and the containers need to be in good condition to ensure good sealing.
(2) Precautions
1. The package is firm
, and the package of 1- (cyanomethyl) -2,3-dibromonaphthalene must be firm and reliable. Due to its chemical composition, if the packaging is damaged, leakage may pollute the environment and endanger human safety. The packaging material has good anti-collision and anti-corrosion properties, such as the use of thick-walled glass bottles, wrapped in shock-proof materials, and placed in the solid outer box.
2. Clear
There must be a clear label outside the container, indicating that the contents of 1- (cyanomethyl) -2,3-dibromonaphthalene are clear, such as flammable, toxic and other phase warnings. In this way, human and phase workers can clearly understand its characteristics, and take positive prevention measures during the removal and release process.
3. Follow the standard
This compound must follow the phase chemical method. In the same way, if the highway needs to be applied for, it should be traveled according to the designated route; the aviation transportation must comply with the price restrictions of aviation transportation products. During the transportation, it is also necessary to regularly check whether the package is in good condition to prevent accidents.
What are the effects of 1- (chloromethyl) -2,3-difluorobenzene on the environment and human health?
In the environment of (cyanomethyl) -2,3-dibromonaphthalene and the impact of human health
(cyanomethyl) -2,3-dibromonaphthalene, it is a chemical substance. Its environment has a similar impact on human health, as follows:
The impact of environmental conditions
1. ** Aquatic organisms **: If this compound enters the aquatic environment, it may cause toxicity to aquatic organisms, aquatic vertebrates, etc. Because it has certain chemical activity, or it may affect the physiological process of aquatic organisms. For example, it may affect the respiratory system of the animal, causing its oxygen capacity to decrease, and even life-threatening; it may affect the young of the aquatic animal, or it may affect its normal breeding, forming or normal behavior.
2. ** Soil microorganisms **: Once introduced into the soil, (cyanomethyl) -2,3-dibromonaphthalene may inhibit the activity of beneficial microorganisms in the soil. Soil microorganisms are essential in soil fertility maintenance and decomposition of organic matter. This compound may modify the soil microbial community, so that the amount of microorganisms in some nitrogen and phosphorus streams is low, which affects the separation of soil and reduces soil fertility.
3. ** Plants **: If plants absorb this compound, it may affect its growth. Or dry plant photosynthesis, which hinders the synthesis of organic compounds, causes them to collapse and wither; it may also affect the absorption of water and organic parts by plant roots, inhibiting the normal growth of the above-ground part of the plant and the underground part.
The shadow of human health
1. ** Eyes of skin: (cyanomethyl) -2,3-dibromonaphthalene is directly connected to the skin, which can cause skin irritation, health problems, etc. If it is not carefully entered into the eyes, it will irritate the eyes more intensely, causing pain, flow, severe cases or eye damage, shadow force.
2. ** Respiratory system: Inhalation of the skin containing this compound can irritate the respiratory tract. In patients, it can cause cough, shortness of breath, severe cases or respiratory diseases such as bronchitis and pneumonia. Periodic exposure to the environment containing (cyanomethyl) -2,3-dibromonaphthalene, or increase the risk of lung diseases.
3. ** Shenzhizai **: Some studies suggest that this compound or Shenzhizai has adverse effects. If it enters the human body, or it causes mental illness, it will cause pain, fatigue, etc. The stage of contact, or the function of the Shenzhizai system, the influence of power, attention, etc.
4. ** Carcinogenesis **: At present, there is no evidence that (cyanomethyl) -2,3-dibromonaphthalene is necessarily carcinogenic, but because it is similar to some known carcinogens, it cannot be ruled out that it has carcinogenicity and needs to be closely noted.
(cyanomethyl) -2,3-dibromonaphthalene, it is a chemical substance. Its environment has a similar impact on human health, as follows:
The impact of environmental conditions
1. ** Aquatic organisms **: If this compound enters the aquatic environment, it may cause toxicity to aquatic organisms, aquatic vertebrates, etc. Because it has certain chemical activity, or it may affect the physiological process of aquatic organisms. For example, it may affect the respiratory system of the animal, causing its oxygen capacity to decrease, and even life-threatening; it may affect the young of the aquatic animal, or it may affect its normal breeding, forming or normal behavior.
2. ** Soil microorganisms **: Once introduced into the soil, (cyanomethyl) -2,3-dibromonaphthalene may inhibit the activity of beneficial microorganisms in the soil. Soil microorganisms are essential in soil fertility maintenance and decomposition of organic matter. This compound may modify the soil microbial community, so that the amount of microorganisms in some nitrogen and phosphorus streams is low, which affects the separation of soil and reduces soil fertility.
3. ** Plants **: If plants absorb this compound, it may affect its growth. Or dry plant photosynthesis, which hinders the synthesis of organic compounds, causes them to collapse and wither; it may also affect the absorption of water and organic parts by plant roots, inhibiting the normal growth of the above-ground part of the plant and the underground part.
The shadow of human health
1. ** Eyes of skin: (cyanomethyl) -2,3-dibromonaphthalene is directly connected to the skin, which can cause skin irritation, health problems, etc. If it is not carefully entered into the eyes, it will irritate the eyes more intensely, causing pain, flow, severe cases or eye damage, shadow force.
2. ** Respiratory system: Inhalation of the skin containing this compound can irritate the respiratory tract. In patients, it can cause cough, shortness of breath, severe cases or respiratory diseases such as bronchitis and pneumonia. Periodic exposure to the environment containing (cyanomethyl) -2,3-dibromonaphthalene, or increase the risk of lung diseases.
3. ** Shenzhizai **: Some studies suggest that this compound or Shenzhizai has adverse effects. If it enters the human body, or it causes mental illness, it will cause pain, fatigue, etc. The stage of contact, or the function of the Shenzhizai system, the influence of power, attention, etc.
4. ** Carcinogenesis **: At present, there is no evidence that (cyanomethyl) -2,3-dibromonaphthalene is necessarily carcinogenic, but because it is similar to some known carcinogens, it cannot be ruled out that it has carcinogenicity and needs to be closely noted.
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