Linshang Chemical
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1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)Benzene
Linshang Chemical
|
HS Code |
275011 |
| Chemical Formula | C9H11ClO4S2 |
| Molecular Weight | 282.769 g/mol |
| Appearance | Solid (Typical) |
| Melting Point | N/A (Specify if known) |
| Boiling Point | N/A (Specify if known) |
| Density | N/A (Specify if known) |
| Solubility In Water | Low solubility (Typical for organic compound with such groups) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane (Typical for non - polar organic compound) |
| Flash Point | N/A (Specify if known) |
| Stability | Stable under normal conditions, but may react with strong oxidizing agents |
As an accredited 1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1-(chloromethyl)-3,5-bis(methylsulfonyl)benzene in a sealed chemical - grade container. |
| Storage | 1-(Chloromethyl)-3,5-bis(methylsulfonyl)benzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent moisture and air exposure. Store it separately from incompatible substances like oxidizing agents, bases, and reducing agents to avoid potential reactions. |
| Shipping | 1-(Chloromethyl)-3,5-bis(methylsulfonyl)benzene is shipped in properly sealed, corrosion - resistant containers. Compliance with hazardous chemical shipping regulations ensures safe transportation to prevent leakage and environmental risks. |
Competitive 1-(Chloromethyl)-3,5-Bis(Methylsulfonyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
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What are the main uses of 1- (chloromethyl) -3,5-bis (methylsulfonyl) benzene?
1 - (cyanomethyl) -3,5 -bis (methylsulfonyl) benzene, which has important uses in many fields.
In the field of medicinal chemistry, it can be used as a key intermediate for the creation of new drugs. Due to the special chemical structure in the molecule, it can interact with specific biological targets. For example, it can design and synthesize drugs with high activity, high selectivity and low toxicity and side effects for certain disease-related proteins and enzymes through reasonable structural modification and optimization, opening up new paths for disease treatment.
In the field of materials science, it can be used to prepare functional materials with special properties. With unique chemical groups, materials are endowed with excellent electrical conductivity, optical properties or thermal stability. For example, in the field of organic optoelectronic materials, with proper treatment and processing, high-efficiency Light Emitting Diode materials can be prepared to improve luminous efficiency and stability, and promote the development of display technology.
In organic synthetic chemistry, as an important synthetic building block, it provides a cornerstone for the construction of complex organic molecules. With the help of reactive groups at different positions, other functional groups or structural fragments can be introduced through diverse organic reactions, such as nucleophilic substitution, coupling reactions, etc., to expand the structural diversity of organic molecules, and to assist organic chemists in synthesizing organic compounds with novel structures and unique properties, thus contributing to the development of organic synthetic chemistry.
In the field of medicinal chemistry, it can be used as a key intermediate for the creation of new drugs. Due to the special chemical structure in the molecule, it can interact with specific biological targets. For example, it can design and synthesize drugs with high activity, high selectivity and low toxicity and side effects for certain disease-related proteins and enzymes through reasonable structural modification and optimization, opening up new paths for disease treatment.
In the field of materials science, it can be used to prepare functional materials with special properties. With unique chemical groups, materials are endowed with excellent electrical conductivity, optical properties or thermal stability. For example, in the field of organic optoelectronic materials, with proper treatment and processing, high-efficiency Light Emitting Diode materials can be prepared to improve luminous efficiency and stability, and promote the development of display technology.
In organic synthetic chemistry, as an important synthetic building block, it provides a cornerstone for the construction of complex organic molecules. With the help of reactive groups at different positions, other functional groups or structural fragments can be introduced through diverse organic reactions, such as nucleophilic substitution, coupling reactions, etc., to expand the structural diversity of organic molecules, and to assist organic chemists in synthesizing organic compounds with novel structures and unique properties, thus contributing to the development of organic synthetic chemistry.
What are the physical properties of 1- (chloromethyl) -3,5-bis (methylsulfonyl) benzene?
1 - (cyanomethyl) -3,5 -bis (methylsulfonyl) benzene is an organic compound that is occasionally involved in the fields of chemical engineering and materials science. Its physical properties are unique and are described as follows:
Looking at its properties, it is mostly white to pale yellow crystalline powder under normal conditions, with a fine texture, just like the purity of the first snow in winter. This color state is easy to observe and identify in various reaction systems, and also adds intuitive visual characteristics to the many reactions it participates in.
The melting point is between 140 and 145 ° C. The melting point plays a key role in the separation, purification and identification of substances. The precise melting point range is like a ruler, which helps researchers determine the purity and authenticity of the substance. When a substance is heated to this temperature range, it quietly changes from a solid state to a liquid state. This phase transition process follows specific physical laws and is the result of the interaction between molecular forces and thermal energy.
Its solubility is also unique, slightly soluble in water, but easily soluble in common organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. The poor solubility in water is due to the dominance of hydrophobic groups in its molecular structure, which makes it difficult to form effective interactions with water molecules. In organic solvents, with the principle of similar miscibility, the molecules of the substance can blend with the organic solvent molecules and disperse uniformly, which provides convenience for its operations in organic synthesis and solution preparation of materials.
As for the density, it is about 1.3-1.4 g/cm ³. This value reflects the mass distribution of the substance in a unit volume. Compared with other related substances, it can assist in evaluating its sedimentation and floating behavior in a specific system, which is of great significance for application scenarios involving fluid dynamics.
In terms of stability, the substance is relatively stable in a dry environment at room temperature and pressure. However, if it encounters extreme chemical environments such as strong oxidizing agents, strong acids or strong bases, some chemical bonds in its molecular structure may be attacked, triggering chemical reactions and causing the substance to deteriorate. In addition, conditions such as light and high temperature may also pose challenges to its stability. Light may induce luminescent chemical reactions, while high temperatures will exacerbate the thermal movement of molecules and increase the risk of chemical bond breakage.
Looking at its properties, it is mostly white to pale yellow crystalline powder under normal conditions, with a fine texture, just like the purity of the first snow in winter. This color state is easy to observe and identify in various reaction systems, and also adds intuitive visual characteristics to the many reactions it participates in.
The melting point is between 140 and 145 ° C. The melting point plays a key role in the separation, purification and identification of substances. The precise melting point range is like a ruler, which helps researchers determine the purity and authenticity of the substance. When a substance is heated to this temperature range, it quietly changes from a solid state to a liquid state. This phase transition process follows specific physical laws and is the result of the interaction between molecular forces and thermal energy.
Its solubility is also unique, slightly soluble in water, but easily soluble in common organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. The poor solubility in water is due to the dominance of hydrophobic groups in its molecular structure, which makes it difficult to form effective interactions with water molecules. In organic solvents, with the principle of similar miscibility, the molecules of the substance can blend with the organic solvent molecules and disperse uniformly, which provides convenience for its operations in organic synthesis and solution preparation of materials.
As for the density, it is about 1.3-1.4 g/cm ³. This value reflects the mass distribution of the substance in a unit volume. Compared with other related substances, it can assist in evaluating its sedimentation and floating behavior in a specific system, which is of great significance for application scenarios involving fluid dynamics.
In terms of stability, the substance is relatively stable in a dry environment at room temperature and pressure. However, if it encounters extreme chemical environments such as strong oxidizing agents, strong acids or strong bases, some chemical bonds in its molecular structure may be attacked, triggering chemical reactions and causing the substance to deteriorate. In addition, conditions such as light and high temperature may also pose challenges to its stability. Light may induce luminescent chemical reactions, while high temperatures will exacerbate the thermal movement of molecules and increase the risk of chemical bond breakage.
What are the chemical properties of 1- (chloromethyl) -3,5-bis (methylsulfonyl) benzene?
1 - (cyanomethyl) -3,5 -bis (methylsulfonyl) benzene, this is a class of organic compounds. Its chemical properties are unique, and it is closely related to the functional group and molecular structure of the compound.
Let's talk about cyanomethyl first, and cyanyl (-CN) has strong electron absorption. Because of its high electronegativity of nitrogen atoms, the carbon-nitrogen triple bond electron cloud is biased towards nitrogen atoms, making cyanocarbons electrophilic. This property makes cyanomethyl compounds easy to participate in nucleophilic substitution reactions. If it interacts with nucleophiles, nucleophiles will attack cyanocarbons, causing cyanoconversion or linking new groups. Under certain conditions, the cyanyl group can also be hydrolyzed to form a carboxyl group (-COOH) or reduced to an amino group (-NH2O), thereby realizing the conversion of the functional group of the compound and deriving a variety of chemical properties.
Looking at methylsulfonyl (-CH 🥰 SO-), there is a double bond between the sulfur atom and the oxygen atom, which has a certain polarity. Sulfinyl atoms in sulfinyl groups can assume various oxidation states, resulting in their active chemical properties. It can participate in redox reactions and can be further oxidized to sulfonyl groups (-SO2O -) or reduced to thioether (-S-). At the same time, methylsulfonyl groups also affect the electron cloud distribution of the benzene ring. Through induction and conjugation effects, the electron cloud density and distribution on the benzene ring are changed, and then the activity and positional selectivity of the electrophilic substitution reaction of the benzene ring are affected.
For the benzene ring, as the core skeleton of this kind of compound, it is aromatic and relatively stable. However, due to the existence of cyanomethyl and methylsulfonyl groups, the distribution of the electron cloud of the benzene ring changes, and its electrophilic substitution activity and check point change. Generally speaking, the electron-withdrawing group cyanomethyl reduces the electron cloud density of the benzene ring and decreases the activity of electrophilic substitution reaction; while methylsulfonyl group has a certain electron conjugation effect, the overall electronic effect is more complex, and the combination of the two effects will make the specific position of the benzene ring more prone to electrophilic substitution reaction.
1 - (cyanomethyl) -3,5 - bis (methylsulfonyl) The interaction between cyanomethyl, methylsulfonyl and benzene ring in benzene shows unique and diverse chemical properties, which shows potential application value in organic synthesis, pharmaceutical chemistry and other fields.
Let's talk about cyanomethyl first, and cyanyl (-CN) has strong electron absorption. Because of its high electronegativity of nitrogen atoms, the carbon-nitrogen triple bond electron cloud is biased towards nitrogen atoms, making cyanocarbons electrophilic. This property makes cyanomethyl compounds easy to participate in nucleophilic substitution reactions. If it interacts with nucleophiles, nucleophiles will attack cyanocarbons, causing cyanoconversion or linking new groups. Under certain conditions, the cyanyl group can also be hydrolyzed to form a carboxyl group (-COOH) or reduced to an amino group (-NH2O), thereby realizing the conversion of the functional group of the compound and deriving a variety of chemical properties.
Looking at methylsulfonyl (-CH 🥰 SO-), there is a double bond between the sulfur atom and the oxygen atom, which has a certain polarity. Sulfinyl atoms in sulfinyl groups can assume various oxidation states, resulting in their active chemical properties. It can participate in redox reactions and can be further oxidized to sulfonyl groups (-SO2O -) or reduced to thioether (-S-). At the same time, methylsulfonyl groups also affect the electron cloud distribution of the benzene ring. Through induction and conjugation effects, the electron cloud density and distribution on the benzene ring are changed, and then the activity and positional selectivity of the electrophilic substitution reaction of the benzene ring are affected.
For the benzene ring, as the core skeleton of this kind of compound, it is aromatic and relatively stable. However, due to the existence of cyanomethyl and methylsulfonyl groups, the distribution of the electron cloud of the benzene ring changes, and its electrophilic substitution activity and check point change. Generally speaking, the electron-withdrawing group cyanomethyl reduces the electron cloud density of the benzene ring and decreases the activity of electrophilic substitution reaction; while methylsulfonyl group has a certain electron conjugation effect, the overall electronic effect is more complex, and the combination of the two effects will make the specific position of the benzene ring more prone to electrophilic substitution reaction.
1 - (cyanomethyl) -3,5 - bis (methylsulfonyl) The interaction between cyanomethyl, methylsulfonyl and benzene ring in benzene shows unique and diverse chemical properties, which shows potential application value in organic synthesis, pharmaceutical chemistry and other fields.
What are the synthesis methods of 1- (chloromethyl) -3,5-bis (methylsulfonyl) benzene?
To prepare 1 - (methoxy) -3,5 - bis (ethoxy carbonyl) benzene, the following methods can be used.
First, benzene is used as the starting material. First, benzene is alkylated with halomethane in the presence of a suitable catalyst, such as aluminum trichloride, to obtain methoxy benzene. Next, using the positioning effect, ethoxy is introduced at the 3,5 - position of methoxy benzene. This can be achieved by acylation reaction, in which ethoxy carbonyl halide reacts with methoxy benzene under the action of a catalyst, and after multiple steps of conversion, the final product is obtained.
Second, starting from aromatics with suitable substituents. If an aromatic hydrocarbon containing methoxy and ethoxy carbonyl substituents can be found, it can be modified by a series of reactions. For example, aromatic hydrocarbons containing halogen atoms can be replaced by nucleophilic substitution reaction with methoxy negative ions to introduce methoxy groups. After a specific reaction, the remaining substituents are converted into ethoxy carbonyl groups.
Third, the strategy of gradually constructing the benzene ring is used. Simple organic compounds, such as compounds containing carbon-carbon double bonds and carbonyl groups, are used to construct the benzene ring through multi-step cyclization reaction. First form a cyclic structure containing methoxy and ethoxy carbonyl precursors, and then aromatization and subsequent modification to obtain 1- (methoxy) -3,5-bis (ethoxy carbonyl) benzene.
All synthesis methods have advantages and disadvantages. The method of starting with benzene as a raw material is easy to obtain, but there are many steps. The reaction conditions need to be precisely controlled to ensure the position of the substituent and the selectivity of the reaction. The method of starting from aromatics containing suitable substituents may reduce the steps, but the suitable starting material may not be easy to obtain. Although the strategy of gradually constructing benzene rings is innovative, the reaction conditions are harsh and the reaction operation requirements are very high. In actual synthesis, the most suitable route is selected according to factors such as raw material availability, reaction cost, yield and purity requirements.
First, benzene is used as the starting material. First, benzene is alkylated with halomethane in the presence of a suitable catalyst, such as aluminum trichloride, to obtain methoxy benzene. Next, using the positioning effect, ethoxy is introduced at the 3,5 - position of methoxy benzene. This can be achieved by acylation reaction, in which ethoxy carbonyl halide reacts with methoxy benzene under the action of a catalyst, and after multiple steps of conversion, the final product is obtained.
Second, starting from aromatics with suitable substituents. If an aromatic hydrocarbon containing methoxy and ethoxy carbonyl substituents can be found, it can be modified by a series of reactions. For example, aromatic hydrocarbons containing halogen atoms can be replaced by nucleophilic substitution reaction with methoxy negative ions to introduce methoxy groups. After a specific reaction, the remaining substituents are converted into ethoxy carbonyl groups.
Third, the strategy of gradually constructing the benzene ring is used. Simple organic compounds, such as compounds containing carbon-carbon double bonds and carbonyl groups, are used to construct the benzene ring through multi-step cyclization reaction. First form a cyclic structure containing methoxy and ethoxy carbonyl precursors, and then aromatization and subsequent modification to obtain 1- (methoxy) -3,5-bis (ethoxy carbonyl) benzene.
All synthesis methods have advantages and disadvantages. The method of starting with benzene as a raw material is easy to obtain, but there are many steps. The reaction conditions need to be precisely controlled to ensure the position of the substituent and the selectivity of the reaction. The method of starting from aromatics containing suitable substituents may reduce the steps, but the suitable starting material may not be easy to obtain. Although the strategy of gradually constructing benzene rings is innovative, the reaction conditions are harsh and the reaction operation requirements are very high. In actual synthesis, the most suitable route is selected according to factors such as raw material availability, reaction cost, yield and purity requirements.
What are the precautions for storing and transporting 1- (chloromethyl) -3,5-bis (methylsulfonyl) benzene?
1-% (cyanomethyl) -3,5-bis (formylhydrazide) benzene should pay attention to the following matters during storage and transportation:
First, storage. Choose a cool, dry and well-ventilated place. This substance is quite sensitive to humidity and temperature, and high temperature and high humidity environments can easily cause chemical reactions to occur, which in turn affects the quality. For example, when the ambient humidity is high, its formylhydrazide group may react with water vapor, hydrolysis and other reactions. Store away from fire and heat sources, because the substance may be flammable, and there is a risk of combustion in case of open flames and hot topics. And it should be stored separately from oxidizing agents, acids, alkalis, etc. Because of its active chemical properties, contact with these substances may cause violent reactions. Like oxidizing agents may oxidize formyl hydrazide, changing its structure and properties.
Second, transportation. It is necessary to ensure that the packaging is complete and sealed. If the packaging is damaged, it may leak during transportation, which will not only cause losses, but also may change due to exposure to air, moisture, etc., and even cause harm to the environment. During transportation, relevant regulations on the transportation of hazardous chemicals should be followed, and corresponding fire protection equipment and emergency treatment equipment should be equipped. Transportation vehicles should follow the designated route to avoid sensitive areas such as densely populated areas and water sources. For example, in case of leakage during transportation, fire protection equipment can be used for emergency treatment in a timely manner to prevent the expansion of the accident. Transport personnel should also undergo professional training to familiarize themselves with the characteristics of the substance and emergency treatment methods, so as to ensure the safety of storage and transportation and avoid adverse consequences due to improper operation.
First, storage. Choose a cool, dry and well-ventilated place. This substance is quite sensitive to humidity and temperature, and high temperature and high humidity environments can easily cause chemical reactions to occur, which in turn affects the quality. For example, when the ambient humidity is high, its formylhydrazide group may react with water vapor, hydrolysis and other reactions. Store away from fire and heat sources, because the substance may be flammable, and there is a risk of combustion in case of open flames and hot topics. And it should be stored separately from oxidizing agents, acids, alkalis, etc. Because of its active chemical properties, contact with these substances may cause violent reactions. Like oxidizing agents may oxidize formyl hydrazide, changing its structure and properties.
Second, transportation. It is necessary to ensure that the packaging is complete and sealed. If the packaging is damaged, it may leak during transportation, which will not only cause losses, but also may change due to exposure to air, moisture, etc., and even cause harm to the environment. During transportation, relevant regulations on the transportation of hazardous chemicals should be followed, and corresponding fire protection equipment and emergency treatment equipment should be equipped. Transportation vehicles should follow the designated route to avoid sensitive areas such as densely populated areas and water sources. For example, in case of leakage during transportation, fire protection equipment can be used for emergency treatment in a timely manner to prevent the expansion of the accident. Transport personnel should also undergo professional training to familiarize themselves with the characteristics of the substance and emergency treatment methods, so as to ensure the safety of storage and transportation and avoid adverse consequences due to improper operation.
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