Linshang Chemical
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1-(Chloromethyl)-3,5-Dimethoxybenzene
Linshang Chemical
|
HS Code |
272157 |
| Chemical Formula | C9H11ClO2 |
| Molar Mass | 186.635 g/mol |
| Appearance | Typically a colorless to light - yellow liquid |
| Boiling Point | Around 250 - 255 °C |
| Density | Approx. 1.14 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, dichloromethane |
| Flash Point | Approx. 107 °C |
| Vapor Pressure | Low vapor pressure at room temperature |
As an accredited 1-(Chloromethyl)-3,5-Dimethoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 1-(chloromethyl)-3,5 -dimethoxybenzene in a sealed, labeled chemical - grade bottle. |
| Storage | 1-(Chloromethyl)-3,5 -dimethoxybenzene should be stored in a cool, dry, well - ventilated area away from sources of heat, ignition, and oxidizing agents. Keep it in a tightly sealed container, preferably in a corrosion - resistant material. Store it separately from incompatible substances like strong bases and reactive metals to prevent potential chemical reactions. |
| Shipping | 1-(Chloromethyl)-3,5 -dimethoxybenzene is shipped in sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper handling to prevent spills and exposure during transit. |
Competitive 1-(Chloromethyl)-3,5-Dimethoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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As a leading 1-(Chloromethyl)-3,5-Dimethoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1- (chloromethyl) -3,5-dimethoxybenzene?
1 - (cyanomethyl) - 3,5 - diethoxybenzene, this substance is an important raw material for organic synthesis, and has key uses in many fields such as medicine, pesticides and materials science.
In the field of medicine, it is a key intermediate for the synthesis of various drugs. For example, some cardiovascular disease treatment drugs, by skillfully using the special chemical structure of 1 - (cyanomethyl) - 3,5 - diethoxybenzene, through a series of organic reactions, can construct molecular structures with specific pharmacological activities, which help to regulate human physiology and achieve the purpose of treating diseases.
In the field of pesticides, this is used as a starting material to synthesize pesticides with high insecticidal and bactericidal properties. Due to its structure, it can interact with specific biomolecules in pests or pathogens, or interfere with their normal physiological and metabolic processes, or destroy their cellular structures, thus exerting excellent control effects, assisting in the prevention and control of pests and diseases in agricultural production, and improving crop yield and quality.
In the field of materials science, 1- (cyanomethyl) -3,5-diethoxylbenzene can participate in the synthesis of high-performance materials. For example, some new polymer materials, when introduced into polymer structures, can significantly improve the physical and chemical properties of materials, such as improving the thermal stability, mechanical strength and chemical corrosion resistance of materials. They are widely used in high-end fields such as aerospace, electronics and electrical appliances to meet the strict requirements of high-performance materials in these fields.
In the field of medicine, it is a key intermediate for the synthesis of various drugs. For example, some cardiovascular disease treatment drugs, by skillfully using the special chemical structure of 1 - (cyanomethyl) - 3,5 - diethoxybenzene, through a series of organic reactions, can construct molecular structures with specific pharmacological activities, which help to regulate human physiology and achieve the purpose of treating diseases.
In the field of pesticides, this is used as a starting material to synthesize pesticides with high insecticidal and bactericidal properties. Due to its structure, it can interact with specific biomolecules in pests or pathogens, or interfere with their normal physiological and metabolic processes, or destroy their cellular structures, thus exerting excellent control effects, assisting in the prevention and control of pests and diseases in agricultural production, and improving crop yield and quality.
In the field of materials science, 1- (cyanomethyl) -3,5-diethoxylbenzene can participate in the synthesis of high-performance materials. For example, some new polymer materials, when introduced into polymer structures, can significantly improve the physical and chemical properties of materials, such as improving the thermal stability, mechanical strength and chemical corrosion resistance of materials. They are widely used in high-end fields such as aerospace, electronics and electrical appliances to meet the strict requirements of high-performance materials in these fields.
What are the physical properties of 1- (chloromethyl) -3,5-dimethoxybenzene?
1- (cyanomethyl) -3,5-dimethoxyphenylsilicon, which is an organosilicon compound. Its physical properties are crucial for its application in many fields.
First, let's talk about the appearance. Under normal conditions, 1- (cyanomethyl) -3,5-dimethoxyphenylsilicon is mostly a colorless to light yellow transparent liquid. This appearance characteristic makes it easy to observe its state changes and reaction processes in many experimental and industrial processes.
In terms of melting point, the substance has a low melting point, which indicates that it is easy to convert from solid to liquid under relatively mild conditions, which facilitates its processing and application. In some processes that require heat treatment, a lower melting point means that energy consumption can be reduced and production efficiency can be improved.
The boiling point is relatively high, which makes it stable in liquid state at higher temperatures, and it is not easy to quickly vaporize and dissipate due to temperature increase. This property makes it a stable reaction medium or separation object in high temperature reaction systems or distillation operations.
Solubility is also an important physical property. 1- (cyanomethyl) -3,5-dimethoxyphenylsilane is soluble in common organic solvents such as toluene, dichloromethane, etc. Good solubility makes it able to be fully mixed with other organic compounds in solution, which is conducive to the development of various organic synthesis reactions. In application scenarios such as the preparation of composites or coatings, it can be uniformly dispersed in the organic matrix to enhance material properties.
The density is moderate, which affects its distribution and phase behavior in the mixture. When it comes to operations such as stratification and extraction, the density characteristics determine its location and the difficulty of separation.
In addition, the refractive index of the substance also has a specific value. The refractive index can be used as an indicator for identification and purity detection. Different purity of 1- (cyanomethyl) -3,5-dimethoxyphenylsilicon, the refractive index will vary slightly, providing an effective means for quality control.
First, let's talk about the appearance. Under normal conditions, 1- (cyanomethyl) -3,5-dimethoxyphenylsilicon is mostly a colorless to light yellow transparent liquid. This appearance characteristic makes it easy to observe its state changes and reaction processes in many experimental and industrial processes.
In terms of melting point, the substance has a low melting point, which indicates that it is easy to convert from solid to liquid under relatively mild conditions, which facilitates its processing and application. In some processes that require heat treatment, a lower melting point means that energy consumption can be reduced and production efficiency can be improved.
The boiling point is relatively high, which makes it stable in liquid state at higher temperatures, and it is not easy to quickly vaporize and dissipate due to temperature increase. This property makes it a stable reaction medium or separation object in high temperature reaction systems or distillation operations.
Solubility is also an important physical property. 1- (cyanomethyl) -3,5-dimethoxyphenylsilane is soluble in common organic solvents such as toluene, dichloromethane, etc. Good solubility makes it able to be fully mixed with other organic compounds in solution, which is conducive to the development of various organic synthesis reactions. In application scenarios such as the preparation of composites or coatings, it can be uniformly dispersed in the organic matrix to enhance material properties.
The density is moderate, which affects its distribution and phase behavior in the mixture. When it comes to operations such as stratification and extraction, the density characteristics determine its location and the difficulty of separation.
In addition, the refractive index of the substance also has a specific value. The refractive index can be used as an indicator for identification and purity detection. Different purity of 1- (cyanomethyl) -3,5-dimethoxyphenylsilicon, the refractive index will vary slightly, providing an effective means for quality control.
What are the synthesis methods of 1- (chloromethyl) -3,5-dimethoxybenzene?
The synthesis of 1-% (cyanomethyl) -3,5-dimethoxybenzene is a significant issue in the field of organic synthesis. To synthesize this substance, various paths can be achieved.
First, nucleophilic substitution reaction can be used as the initial step. First select suitable halogenated hydrocarbons, such as halogenated cyanomethane, and react with hydroxyl-containing benzene derivatives under alkaline conditions. The base can promote the deprotonation of phenolic hydroxyl groups and enhance their nucleophilicity, making it easier to undergo substitution reactions with halogenated cyanomethane, and introduce cyanomethyl groups into the benzene ring. Subsequently, for the introduction of methoxy groups at the 3,5 position, corresponding methylation reagents, such as dimethyl sulfate or iodomethane, can be selected to achieve methylation of phenolic hydroxyl groups at the 3,5 position under the action of an alkaline catalyst, and finally obtain the target product 1-% (cyanomethyl) -3,5-dimethoxybenzene.
Second, it can also be considered to start with the Fu-gram alkylation reaction of the benzene ring. First, a suitable acyl halide or acid anhydride and benzene under the action of a Lewis acid catalyst, such as anhydrous aluminum trichloride, undergo a Fu-gram acylation reaction, and an acyl group is introduced at a specific position in the benzene ring. After that, the acyl group is converted to an alkyl group through Then, by a method similar to the above nucleophilic substitution reaction, cyanomethyl and methoxy groups are introduced in sequence to complete the synthesis of the target compound.
Furthermore, palladium-catalyzed cross-coupling reaction can also be used. Select a suitable aryl halide or aryl borate, and the reagents related to cyanomethyl and methoxy groups will undergo cross-coupling reaction in the presence of palladium catalyst and ligand to gradually construct the target molecular structure. This method has the advantages of high selectivity and relatively mild conditions, which can effectively avoid the occurrence of some side reactions and improve the yield and purity of the target product.
There are various methods for the synthesis of 1-% (cyanomethyl) -3,5-dimethoxybenzene, and the most suitable synthesis path should be selected according to the actual situation, such as the availability of raw materials, the controllability of reaction conditions, cost and yield.
First, nucleophilic substitution reaction can be used as the initial step. First select suitable halogenated hydrocarbons, such as halogenated cyanomethane, and react with hydroxyl-containing benzene derivatives under alkaline conditions. The base can promote the deprotonation of phenolic hydroxyl groups and enhance their nucleophilicity, making it easier to undergo substitution reactions with halogenated cyanomethane, and introduce cyanomethyl groups into the benzene ring. Subsequently, for the introduction of methoxy groups at the 3,5 position, corresponding methylation reagents, such as dimethyl sulfate or iodomethane, can be selected to achieve methylation of phenolic hydroxyl groups at the 3,5 position under the action of an alkaline catalyst, and finally obtain the target product 1-% (cyanomethyl) -3,5-dimethoxybenzene.
Second, it can also be considered to start with the Fu-gram alkylation reaction of the benzene ring. First, a suitable acyl halide or acid anhydride and benzene under the action of a Lewis acid catalyst, such as anhydrous aluminum trichloride, undergo a Fu-gram acylation reaction, and an acyl group is introduced at a specific position in the benzene ring. After that, the acyl group is converted to an alkyl group through Then, by a method similar to the above nucleophilic substitution reaction, cyanomethyl and methoxy groups are introduced in sequence to complete the synthesis of the target compound.
Furthermore, palladium-catalyzed cross-coupling reaction can also be used. Select a suitable aryl halide or aryl borate, and the reagents related to cyanomethyl and methoxy groups will undergo cross-coupling reaction in the presence of palladium catalyst and ligand to gradually construct the target molecular structure. This method has the advantages of high selectivity and relatively mild conditions, which can effectively avoid the occurrence of some side reactions and improve the yield and purity of the target product.
There are various methods for the synthesis of 1-% (cyanomethyl) -3,5-dimethoxybenzene, and the most suitable synthesis path should be selected according to the actual situation, such as the availability of raw materials, the controllability of reaction conditions, cost and yield.
What should be paid attention to when storing and transporting 1- (chloromethyl) -3,5-dimethoxybenzene?
1 - (Cyanomethyl) - 3,5 - Dimethoxyphenylsilicon must pay attention to the following points when storing and transporting.
Its chemical properties are active, and it is necessary to choose a cool, dry and well-ventilated place during storage. Because it is extremely sensitive to humidity, if the environment is humid, it is easy to cause adverse reactions such as hydrolysis, which will damage its quality. When storing, the container must be tightly sealed to prevent moisture from invading. For example, if placed in a place with high humidity, it may gradually deteriorate and affect subsequent use.
Temperature should not be ignored, and high temperature environments should be avoided. High temperature is very likely to cause thermal decomposition or other chemical reactions. The ideal storage temperature should be maintained within a specific range to prevent temperature fluctuations from posing a threat to its stability.
During transportation, ensure that the packaging is firm and reliable. This substance may be dangerous, so the packaging material needs to be able to withstand a certain external impact to avoid leakage due to package damage during transportation. Transportation vehicles should also maintain appropriate temperature and humidity conditions to meet the storage requirements of the substance.
In addition, relevant regulations on the transportation of hazardous chemicals need to be strictly followed. Transport personnel must be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. In the event of an emergency such as a leak, they should be able to respond quickly and properly to prevent more serious consequences. Only by paying high attention to the above points during storage and transportation can the quality and transportation safety of 1- (cyanomethyl) -3,5-dimethoxyphenylsilicon be ensured.
Its chemical properties are active, and it is necessary to choose a cool, dry and well-ventilated place during storage. Because it is extremely sensitive to humidity, if the environment is humid, it is easy to cause adverse reactions such as hydrolysis, which will damage its quality. When storing, the container must be tightly sealed to prevent moisture from invading. For example, if placed in a place with high humidity, it may gradually deteriorate and affect subsequent use.
Temperature should not be ignored, and high temperature environments should be avoided. High temperature is very likely to cause thermal decomposition or other chemical reactions. The ideal storage temperature should be maintained within a specific range to prevent temperature fluctuations from posing a threat to its stability.
During transportation, ensure that the packaging is firm and reliable. This substance may be dangerous, so the packaging material needs to be able to withstand a certain external impact to avoid leakage due to package damage during transportation. Transportation vehicles should also maintain appropriate temperature and humidity conditions to meet the storage requirements of the substance.
In addition, relevant regulations on the transportation of hazardous chemicals need to be strictly followed. Transport personnel must be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. In the event of an emergency such as a leak, they should be able to respond quickly and properly to prevent more serious consequences. Only by paying high attention to the above points during storage and transportation can the quality and transportation safety of 1- (cyanomethyl) -3,5-dimethoxyphenylsilicon be ensured.
Is 1- (chloromethyl) -3,5-dimethoxybenzene toxic and what are its effects on the environment?
1 - (hydroxymethyl) - 3,5 - dimethoxybenzene, this substance is toxic and has a significant impact in the environment.
Its toxicity is also, if the substance enters the organism, it may hinder the metabolism of cells and the stability of genetic materials. Experiments have shown that if animals are exposed to this chemical, they may have organ damage and reproductive disorders. In humans, if long-term exposure to the environment containing this substance may increase the risk of cancer, it will also affect the nervous system and immune system, causing cognitive dysfunction and immunocompromised symptoms.
When it comes to the impact on the environment, it may be persistent in the environment and difficult to degrade rapidly through natural processes. Once released into soil and water bodies, it can persist for a long time, causing soil fertility to decline and affecting plant growth; in water bodies, it will harm aquatic organisms and destroy the balance of aquatic ecosystems. It may also cause greater harm to organisms at the top of the food chain through the transmission and enrichment of the food chain, ultimately changing the structure and function of the ecosystem.
Therefore, for toxic and environmentally harmful substances such as 1- (hydroxymethyl) -3,5-dimethoxybenzene, it should be treated with caution, and control should be strengthened in industrial production and use to prevent irreparable damage to organisms and the environment.
Its toxicity is also, if the substance enters the organism, it may hinder the metabolism of cells and the stability of genetic materials. Experiments have shown that if animals are exposed to this chemical, they may have organ damage and reproductive disorders. In humans, if long-term exposure to the environment containing this substance may increase the risk of cancer, it will also affect the nervous system and immune system, causing cognitive dysfunction and immunocompromised symptoms.
When it comes to the impact on the environment, it may be persistent in the environment and difficult to degrade rapidly through natural processes. Once released into soil and water bodies, it can persist for a long time, causing soil fertility to decline and affecting plant growth; in water bodies, it will harm aquatic organisms and destroy the balance of aquatic ecosystems. It may also cause greater harm to organisms at the top of the food chain through the transmission and enrichment of the food chain, ultimately changing the structure and function of the ecosystem.
Therefore, for toxic and environmentally harmful substances such as 1- (hydroxymethyl) -3,5-dimethoxybenzene, it should be treated with caution, and control should be strengthened in industrial production and use to prevent irreparable damage to organisms and the environment.
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