Linshang Chemical
PRODUCTS
1-(Chloromethyl)-4-Fluorobenzene
Linshang Chemical
|
HS Code |
549977 |
| Chemical Formula | C7H6ClF |
| Molar Mass | 144.57 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 172 - 174 °C |
| Density | 1.192 g/cm³ |
| Solubility In Water | Insoluble |
| Flash Point | 59 °C |
| Refractive Index | 1.501 |
As an accredited 1-(Chloromethyl)-4-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1-(chloromethyl)-4-fluorobenzene packaged in a sealed, corrosion - resistant bottle. |
| Storage | 1-(Chloromethyl)-4-fluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container, preferably made of corrosion - resistant materials. Label the storage container clearly to prevent misidentification. This helps maintain its chemical integrity and ensures safety. |
| Shipping | 1-(Chloromethyl)-4-fluorobenzene is shipped in accordance with strict chemical regulations. Packed in suitable, leak - proof containers, it's transported by specialized carriers ensuring safety during transit to prevent any environmental or safety risks. |
Competitive 1-(Chloromethyl)-4-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-(Chloromethyl)-4-Fluorobenzene in China?
As a trusted 1-(Chloromethyl)-4-Fluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-(Chloromethyl)-4-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1- (chloromethyl) -4-fluorobenzene?
1- (cyanomethyl) -4-cyanonaphthalene has a wide range of main uses. This compound is a crucial intermediate in the field of organic synthesis.
In the field of medicinal chemistry, 1- (cyanomethyl) -4-cyanonaphthalene can be used as a key starting material for the preparation of many biologically active drug molecules. Through a series of delicate chemical reactions, such as nucleophilic substitution and cyclization, its structure can be modified and modified to obtain compounds with specific pharmacological effects. For example, a drug skeleton with anti-tumor activity can be constructed, and the growth of tumor cells can be inhibited by regulating its interaction with tumor cell targets.
In the field of materials science, this substance also shows unique application value. Due to its structural properties, it can participate in the synthesis of polymer materials, giving the materials special physical and chemical properties. For example, introducing it into polymer systems can improve the thermal stability, mechanical properties and optical properties of materials. By copolymerizing with other monomers, new materials with specific functions can be prepared, which have potential applications in electronic devices, optical films, etc.
Furthermore, in the preparation of fine chemical products, 1- (cyanomethyl) -4-cyanonaphthalene also plays an important role. It can be used to synthesize high-value-added fine chemicals, such as special dyes, fragrances, etc. Utilizing its unique chemical structure, products with novel color or aroma characteristics can be designed and synthesized to meet the market demand for high-end fine chemical products.
In summary, 1- (cyanomethyl) -4-cyanonaphthalene plays an indispensable role in many fields such as medicine, materials, and fine chemicals due to its special chemical structure, providing an important material basis for innovation and development in various fields.
In the field of medicinal chemistry, 1- (cyanomethyl) -4-cyanonaphthalene can be used as a key starting material for the preparation of many biologically active drug molecules. Through a series of delicate chemical reactions, such as nucleophilic substitution and cyclization, its structure can be modified and modified to obtain compounds with specific pharmacological effects. For example, a drug skeleton with anti-tumor activity can be constructed, and the growth of tumor cells can be inhibited by regulating its interaction with tumor cell targets.
In the field of materials science, this substance also shows unique application value. Due to its structural properties, it can participate in the synthesis of polymer materials, giving the materials special physical and chemical properties. For example, introducing it into polymer systems can improve the thermal stability, mechanical properties and optical properties of materials. By copolymerizing with other monomers, new materials with specific functions can be prepared, which have potential applications in electronic devices, optical films, etc.
Furthermore, in the preparation of fine chemical products, 1- (cyanomethyl) -4-cyanonaphthalene also plays an important role. It can be used to synthesize high-value-added fine chemicals, such as special dyes, fragrances, etc. Utilizing its unique chemical structure, products with novel color or aroma characteristics can be designed and synthesized to meet the market demand for high-end fine chemical products.
In summary, 1- (cyanomethyl) -4-cyanonaphthalene plays an indispensable role in many fields such as medicine, materials, and fine chemicals due to its special chemical structure, providing an important material basis for innovation and development in various fields.
What are the physical properties of 1- (chloromethyl) -4-fluorobenzene?
1 - (cyanomethyl) - 4 - cyanonaphthalene is an organic compound, and its physical properties are particularly important, which is of key significance in chemical research and practical applications.
1 - (cyanomethyl) - 4 - cyanonaphthalene appears as a solid state under normal temperature and pressure. Its melting point value is a key indicator to define the transformation of its physical state. After many experiments, it can be seen that the melting point of this compound is relatively high, which makes it capable of maintaining a solid state in ordinary environments and has good stability. High melting points indicate strong intermolecular forces and tight and orderly molecular arrangements.
Looking at its solubility, 1- (cyanomethyl) -4-cyanonaphthalene shows a certain dissolution tendency in organic solvents. Common aromatic hydrocarbon solvents, such as benzene and toluene, have a significant dissolution effect on it. Because the molecular structure of this compound is similar to that of aromatic hydrocarbon solvents, the naphthalene ring structure contained in the molecule can be combined with aromatic hydrocarbon solvents through the interaction of π-π and other forces to achieve dissolution. However, in water, its solubility is very small, because water is a highly polar solvent, and the overall polarity of 1- (cyanomethyl) -4-cyanonaphthalene molecules is weak, and the force between water molecules is difficult to overcome the strong hydrogen bond between water molecules, so it is difficult to dissolve in water.
The color state of 1- (cyanomethyl) -4-cyanonaphthalene cannot be ignored. Its appearance is often white to light yellow crystalline powder. This color state characteristic not only reflects the absorption and reflection characteristics of its molecular structure to light, but also can be used as the basis for preliminary identification of the compound. In actual operation and observation, the change of color state may suggest the difference in purity. If it contains impurities, the color state may change significantly.
In addition, the density of the compound is also an important physical property. Although the exact value needs to be determined under specific experimental conditions, its density is closely related to the molecular weight and the way of molecular packing. Relatively large molecular masses and tight molecular packing patterns may give it a certain density value, which are key considerations in studies involving the separation, purification, and distribution of the compound in different media.
1 - (cyanomethyl) - 4 - cyanonaphthalene appears as a solid state under normal temperature and pressure. Its melting point value is a key indicator to define the transformation of its physical state. After many experiments, it can be seen that the melting point of this compound is relatively high, which makes it capable of maintaining a solid state in ordinary environments and has good stability. High melting points indicate strong intermolecular forces and tight and orderly molecular arrangements.
Looking at its solubility, 1- (cyanomethyl) -4-cyanonaphthalene shows a certain dissolution tendency in organic solvents. Common aromatic hydrocarbon solvents, such as benzene and toluene, have a significant dissolution effect on it. Because the molecular structure of this compound is similar to that of aromatic hydrocarbon solvents, the naphthalene ring structure contained in the molecule can be combined with aromatic hydrocarbon solvents through the interaction of π-π and other forces to achieve dissolution. However, in water, its solubility is very small, because water is a highly polar solvent, and the overall polarity of 1- (cyanomethyl) -4-cyanonaphthalene molecules is weak, and the force between water molecules is difficult to overcome the strong hydrogen bond between water molecules, so it is difficult to dissolve in water.
The color state of 1- (cyanomethyl) -4-cyanonaphthalene cannot be ignored. Its appearance is often white to light yellow crystalline powder. This color state characteristic not only reflects the absorption and reflection characteristics of its molecular structure to light, but also can be used as the basis for preliminary identification of the compound. In actual operation and observation, the change of color state may suggest the difference in purity. If it contains impurities, the color state may change significantly.
In addition, the density of the compound is also an important physical property. Although the exact value needs to be determined under specific experimental conditions, its density is closely related to the molecular weight and the way of molecular packing. Relatively large molecular masses and tight molecular packing patterns may give it a certain density value, which are key considerations in studies involving the separation, purification, and distribution of the compound in different media.
What are the chemical properties of 1- (chloromethyl) -4-fluorobenzene?
1 - (cyanomethyl) - 4 - cyanonaphthalene is an organic compound. This compound has unique chemical properties. Its molecular structure contains cyanyl and naphthalene groups, which cause it to have specific reactivity.
Cyanyl group has strong electron absorption. In 1 - (cyanomethyl) - 4 - cyanonaphthalene, the cyanyl group changes the distribution of molecular electron clouds and enhances its polarity. This polarity affects the solubility of the compound, and it is better in polar solvents or in non-polar solvents.
Furthermore, cyanyl groups can participate in many chemical reactions. If it can be hydrolyzed to form a carboxyl group, or converted into an amino group by reduction reaction, 1- (cyanomethyl) -4-cyanonaphthalene becomes an important intermediate in organic synthesis.
Naphthalene is a fused cyclic aromatic hydrocarbon structure, which endows the compound with certain stability and conjugate system. The conjugate system makes the compound have special optical and electrical properties, or can be applied to the field of optoelectronic materials.
At the same time, naphthalene is also an active check point for electrophilic substitution reactions. Due to its electron cloud density distribution, halogenation, nitration, sulfonation and other electrophilic substitution reactions can occur at specific locations, providing a way to introduce other functional groups and expanding the application
1- (cyanomethyl) -4 -cyanonaphthalene has a variety of chemical properties due to the synergistic effect of cyanyl and naphthalene, and has potential application value in organic synthesis, materials science and other fields. It is indeed a compound worthy of further study.
Cyanyl group has strong electron absorption. In 1 - (cyanomethyl) - 4 - cyanonaphthalene, the cyanyl group changes the distribution of molecular electron clouds and enhances its polarity. This polarity affects the solubility of the compound, and it is better in polar solvents or in non-polar solvents.
Furthermore, cyanyl groups can participate in many chemical reactions. If it can be hydrolyzed to form a carboxyl group, or converted into an amino group by reduction reaction, 1- (cyanomethyl) -4-cyanonaphthalene becomes an important intermediate in organic synthesis.
Naphthalene is a fused cyclic aromatic hydrocarbon structure, which endows the compound with certain stability and conjugate system. The conjugate system makes the compound have special optical and electrical properties, or can be applied to the field of optoelectronic materials.
At the same time, naphthalene is also an active check point for electrophilic substitution reactions. Due to its electron cloud density distribution, halogenation, nitration, sulfonation and other electrophilic substitution reactions can occur at specific locations, providing a way to introduce other functional groups and expanding the application
1- (cyanomethyl) -4 -cyanonaphthalene has a variety of chemical properties due to the synergistic effect of cyanyl and naphthalene, and has potential application value in organic synthesis, materials science and other fields. It is indeed a compound worthy of further study.
What are the preparation methods of 1- (chloromethyl) -4-fluorobenzene?
There are various ways to prepare 1- (cyanomethyl) -4 -cyanonaphthalene, which are described in detail as follows:
First, the naphthalene can be started from the naphthalene. First, the naphthalene and the halogenated cyanomethyl reagent are used for electrophilic substitution under suitable catalysts and reaction conditions. Halogenated cyanomethyl reagents such as chloroacetonitrile, and Lewis acids such as aluminum trichloride are used as catalysts. The aromatic ring of naphthalene has electron-rich properties and can be electrophilically substituted with the reagent. Cyanomethyl is introduced into the specific position of the naphthalene ring. However, this process requires fine regulation of the reaction conditions. Due to the different activities of the
Second, it is constructed with an intermediate containing a cyanyl group. For example, a cyanyl compound with a suitable substituent is prepared first, and then a naphthalene ring is constructed by cyclization reaction and cyanomethyl is introduced. For example, with compounds like m-cyanobenzoic acid, a chain-like intermediate containing unsaturated bonds is first formed through a multi-step reaction, and then an intramolecular cyclization occurs under suitable conditions to form a 1- (cyanomethyl) -4-cyanonaphthalene structure. This approach step is slightly complicated, but the position of the substituent can be better controlled.
Third, a metal-catalyzed coupling reaction can be used. Select a suitable halogenated naphthalene derivative and a cyanomethylation reagent, and a coupling reaction occurs under the action of a metal catalyst such as a pall The activity of the halogen atom in the halogenated naphthalene derivative has a great influence on the reaction. The structure of the cyanomethylation reagent also needs to be carefully selected, and the alkali, ligand and other factors of the reaction system need to be optimized in order to improve the yield of the target product.
All production methods have their own advantages and disadvantages. It is necessary to choose carefully according to actual needs, considering many factors such as raw material availability, cost, yield and product purity.
First, the naphthalene can be started from the naphthalene. First, the naphthalene and the halogenated cyanomethyl reagent are used for electrophilic substitution under suitable catalysts and reaction conditions. Halogenated cyanomethyl reagents such as chloroacetonitrile, and Lewis acids such as aluminum trichloride are used as catalysts. The aromatic ring of naphthalene has electron-rich properties and can be electrophilically substituted with the reagent. Cyanomethyl is introduced into the specific position of the naphthalene ring. However, this process requires fine regulation of the reaction conditions. Due to the different activities of the
Second, it is constructed with an intermediate containing a cyanyl group. For example, a cyanyl compound with a suitable substituent is prepared first, and then a naphthalene ring is constructed by cyclization reaction and cyanomethyl is introduced. For example, with compounds like m-cyanobenzoic acid, a chain-like intermediate containing unsaturated bonds is first formed through a multi-step reaction, and then an intramolecular cyclization occurs under suitable conditions to form a 1- (cyanomethyl) -4-cyanonaphthalene structure. This approach step is slightly complicated, but the position of the substituent can be better controlled.
Third, a metal-catalyzed coupling reaction can be used. Select a suitable halogenated naphthalene derivative and a cyanomethylation reagent, and a coupling reaction occurs under the action of a metal catalyst such as a pall The activity of the halogen atom in the halogenated naphthalene derivative has a great influence on the reaction. The structure of the cyanomethylation reagent also needs to be carefully selected, and the alkali, ligand and other factors of the reaction system need to be optimized in order to improve the yield of the target product.
All production methods have their own advantages and disadvantages. It is necessary to choose carefully according to actual needs, considering many factors such as raw material availability, cost, yield and product purity.
What are the precautions for storing and transporting 1- (chloromethyl) -4-fluorobenzene?
For mercury (mercury), many things should be paid attention to during storage and transportation.
Mercury is volatile and its vapor is highly toxic. When storing, it must be sealed in a container to prevent the volatilization of mercury from escaping, causing pollution to the surrounding environment and endangering humans and animals. The containers used should be strong and resistant to corrosion. It is better to use thick-walled glass or metal materials. It needs to be carefully checked and there should be no cracks at all.
During transportation, it is also necessary to ensure that the mercury seal is intact. Because of its high density, vibration or collision can easily cause damage to the container, so it must be properly fixed to avoid violent shaking. The temperature of the transportation environment should also be paid attention to and should not be too high to prevent the evaporation of mercury from intensifying.
Furthermore, mercury dissolves most metals, forming amalgam. Containers and related tools used for storage and transportation should not be metals that are easily interacted with mercury, such as aluminum.
In addition, people engaged in the storage and transportation of mercury must have professional training, be familiar with the characteristics and hazards of mercury, and know how to deal with emergency. If a mercury leak unfortunately occurs, people should be evacuated immediately, ventilation should be strengthened, and sulfur powder should be quickly covered to form mercury sulfide to reduce toxicity.
When storing and transporting mercury, every step is crucial, from container selection, sealing treatment, shock-proof fixing, to personnel professionalism, etc. A little carelessness can lead to serious consequences, endangering the environment and personal safety.
Mercury is volatile and its vapor is highly toxic. When storing, it must be sealed in a container to prevent the volatilization of mercury from escaping, causing pollution to the surrounding environment and endangering humans and animals. The containers used should be strong and resistant to corrosion. It is better to use thick-walled glass or metal materials. It needs to be carefully checked and there should be no cracks at all.
During transportation, it is also necessary to ensure that the mercury seal is intact. Because of its high density, vibration or collision can easily cause damage to the container, so it must be properly fixed to avoid violent shaking. The temperature of the transportation environment should also be paid attention to and should not be too high to prevent the evaporation of mercury from intensifying.
Furthermore, mercury dissolves most metals, forming amalgam. Containers and related tools used for storage and transportation should not be metals that are easily interacted with mercury, such as aluminum.
In addition, people engaged in the storage and transportation of mercury must have professional training, be familiar with the characteristics and hazards of mercury, and know how to deal with emergency. If a mercury leak unfortunately occurs, people should be evacuated immediately, ventilation should be strengthened, and sulfur powder should be quickly covered to form mercury sulfide to reduce toxicity.
When storing and transporting mercury, every step is crucial, from container selection, sealing treatment, shock-proof fixing, to personnel professionalism, etc. A little carelessness can lead to serious consequences, endangering the environment and personal safety.
Scan to WhatsApp
