Linshang Chemical
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1-Chloromethyl-4-Methoxybenzene
Linshang Chemical
|
HS Code |
779586 |
| Chemical Formula | C8H9ClO |
| Molar Mass | 156.609 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 207 - 208 °C |
| Melting Point | N/A |
| Density | 1.124 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | 82 °C |
| Odor | Pungent odor |
| Cas Number | 824-94-2 |
| Structural Formula | CH3OC6H4CH2Cl |
As an accredited 1-Chloromethyl-4-Methoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - Chloromethyl - 4 - methoxybenzene, 500g packed in a sealed, corrosion - resistant glass bottle. |
| Storage | 1 - Chloromethyl - 4 - methoxybenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames due to its flammability risk. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents, strong acids, and bases to avoid potential chemical reactions. Label the storage clearly for easy identification and safety. |
| Shipping | 1 - Chloromethyl - 4 - methoxybenzene is a chemical. For shipping, it must be in properly sealed, corrosion - resistant containers. Label containers clearly with hazard info. Ship via approved carriers following all regulations for hazardous chemicals. |
Competitive 1-Chloromethyl-4-Methoxybenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Chloromethyl-4-Methoxybenzene in China?
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Chloromethyl-4-Methoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 1-chloromethyl-4-methoxybenzene?
1-Chloromethyl-4-methoxybenzene is p-methoxybenzyl chloride, and this substance has a wide range of uses.
In the field of organic synthesis, it is a key intermediate. Due to its high activity in the structure of chloromethyl, it can participate in many chemical reactions. For example, nucleophilic substitution reactions, chlorine atoms can be replaced by many nucleophiles. Reacting with alcohols can generate ether compounds; reacting with amines can prepare amine substitutions. This property makes it important in the synthesis of complex organic molecules. In the synthesis of many drugs, natural products and fine chemicals, it is often used as a starting material to build key structural units.
It also has important uses in materials science. It can be introduced into polymer materials through chemical reactions to impart special properties to the materials. For example, after introduction, it may change the surface hydrophilicity of the material, or enhance the interaction between the material and other substances, improve the adhesion and compatibility of the material, etc., thereby broadening the application range of the material for the preparation of special coatings, adhesives, etc.
In addition, in the fragrance industry, it has also been involved. Through a series of reactions, compounds with special aromas are synthesized to add a unique smell to the fragrance, improve the quality and uniqueness of the fragrance, and are used to prepare various perfumes, flavors and other products.
However, extra caution is required when using 1-chloromethyl-4-methoxybenzene, as it is toxic and irritating. Strict safety procedures should be followed during operation, and protective measures should be taken to ensure personal safety and environmental safety.
In the field of organic synthesis, it is a key intermediate. Due to its high activity in the structure of chloromethyl, it can participate in many chemical reactions. For example, nucleophilic substitution reactions, chlorine atoms can be replaced by many nucleophiles. Reacting with alcohols can generate ether compounds; reacting with amines can prepare amine substitutions. This property makes it important in the synthesis of complex organic molecules. In the synthesis of many drugs, natural products and fine chemicals, it is often used as a starting material to build key structural units.
It also has important uses in materials science. It can be introduced into polymer materials through chemical reactions to impart special properties to the materials. For example, after introduction, it may change the surface hydrophilicity of the material, or enhance the interaction between the material and other substances, improve the adhesion and compatibility of the material, etc., thereby broadening the application range of the material for the preparation of special coatings, adhesives, etc.
In addition, in the fragrance industry, it has also been involved. Through a series of reactions, compounds with special aromas are synthesized to add a unique smell to the fragrance, improve the quality and uniqueness of the fragrance, and are used to prepare various perfumes, flavors and other products.
However, extra caution is required when using 1-chloromethyl-4-methoxybenzene, as it is toxic and irritating. Strict safety procedures should be followed during operation, and protective measures should be taken to ensure personal safety and environmental safety.
What are the physical properties of 1-chloromethyl-4-methoxybenzene?
1-Chloromethyl-4-methoxybenzene is an organic compound, also known as p-methoxybenzyl chloride. The physical properties of this substance are quite important, and it is related to its performance in various chemical processes and practical applications.
Its appearance is usually colorless to light yellow liquid. Looking at its color, it is like the pale yellow chrysanthemum at the beginning of autumn. The colorless part is like a clear spring, and the light yellow part is like the first dye of autumn. Under normal temperature and pressure, this form is easy to observe and operate.
Smell it, it has an irritating smell. This smell is like a sharp blade, which can stimulate the olfactory sense and warn people that it is dangerous. When using and storing, be sure to pay attention to prevent inhalation from damaging the body.
When it comes to the melting point, it is about -6 ° C. Just like the critical point for the initial melting of thin ice in winter, when the temperature rises slightly, it melts into a liquid. The lower melting point means that its physical state can be changed under relatively mild conditions.
The boiling point is about 213 ° C. At this temperature, the liquid turns into a gas and rises. If water is boiled over a stove fire, it reaches the boiling point and water vapor evaporates. A higher boiling point indicates that it is relatively stable at room temperature and is not easy to evaporate.
The density is about 1.129g/cm ³, which is slightly heavier than water. If it is placed in one place with water, it will sink to the bottom like a stone and settle slowly. This density characteristic is of great significance for the separation and mixing process.
In terms of solubility, it is slightly soluble in water, but soluble in most organic solvents, such as ethanol, ether, etc. Just like fish entering a river, it is difficult to dissolve in the "water" of fresh water, but easily soluble in the "sea" of organic solvents. This characteristic determines its behavior in different solvent systems and has a profound impact on its chemical synthesis and purification operations.
Its appearance is usually colorless to light yellow liquid. Looking at its color, it is like the pale yellow chrysanthemum at the beginning of autumn. The colorless part is like a clear spring, and the light yellow part is like the first dye of autumn. Under normal temperature and pressure, this form is easy to observe and operate.
Smell it, it has an irritating smell. This smell is like a sharp blade, which can stimulate the olfactory sense and warn people that it is dangerous. When using and storing, be sure to pay attention to prevent inhalation from damaging the body.
When it comes to the melting point, it is about -6 ° C. Just like the critical point for the initial melting of thin ice in winter, when the temperature rises slightly, it melts into a liquid. The lower melting point means that its physical state can be changed under relatively mild conditions.
The boiling point is about 213 ° C. At this temperature, the liquid turns into a gas and rises. If water is boiled over a stove fire, it reaches the boiling point and water vapor evaporates. A higher boiling point indicates that it is relatively stable at room temperature and is not easy to evaporate.
The density is about 1.129g/cm ³, which is slightly heavier than water. If it is placed in one place with water, it will sink to the bottom like a stone and settle slowly. This density characteristic is of great significance for the separation and mixing process.
In terms of solubility, it is slightly soluble in water, but soluble in most organic solvents, such as ethanol, ether, etc. Just like fish entering a river, it is difficult to dissolve in the "water" of fresh water, but easily soluble in the "sea" of organic solvents. This characteristic determines its behavior in different solvent systems and has a profound impact on its chemical synthesis and purification operations.
What is the chemical synthesis method of 1-chloromethyl-4-methoxybenzene?
There are many ways to synthesize 1-chloromethyl-4-methoxybenzene, one of which is commonly used as follows.
Start with p-methoxytoluene as the base material, which is easy to obtain. First take an appropriate amount of p-methoxytoluene, place it in the reactor, and add an appropriate amount of initiator, such as azobisisobutyronitrile. Then pass chlorine gas into the kettle, and control the temperature in a suitable environment, about 80-100 degrees Celsius. This is a radical substitution reaction. Under the action of the initiator, chlorine gas produces a chlorine radical, which then replaces with the methyl group of p-methoxytoluene to obtain 1-chloromethyl-4-methoxybenzene. During the reaction, it is necessary to closely observe the temperature, chlorine gas penetration rate and other factors to ensure a smooth reaction.
There are other methods, which can first use p-methoxybenzyl alcohol as raw material. The p-methoxybenzyl alcohol and chlorinated reagents, such as dichlorosulfoxide, are co-placed in the reaction vessel. The two react at room temperature or slightly warmed state. During this process, the chlorine atom of the dichlorosulfoxide replaces the hydroxyl group of the p-methoxybenzyl alcohol to form 1-chloromethyl-4-methoxybenzene, and sulfur dioxide and hydrogen chloride gas escape at the same time. After the reaction is completed, the product is purified by distillation, extraction, etc. to remove its impurities, and pure 1-chloromethyl-4-methoxybenzene can be obtained.
These two are common methods for synthesizing 1-chloromethyl-4-methoxybenzene. In practice, according to the availability of raw materials, cost considerations, product purity and many other factors, choose the appropriate one and use it.
Start with p-methoxytoluene as the base material, which is easy to obtain. First take an appropriate amount of p-methoxytoluene, place it in the reactor, and add an appropriate amount of initiator, such as azobisisobutyronitrile. Then pass chlorine gas into the kettle, and control the temperature in a suitable environment, about 80-100 degrees Celsius. This is a radical substitution reaction. Under the action of the initiator, chlorine gas produces a chlorine radical, which then replaces with the methyl group of p-methoxytoluene to obtain 1-chloromethyl-4-methoxybenzene. During the reaction, it is necessary to closely observe the temperature, chlorine gas penetration rate and other factors to ensure a smooth reaction.
There are other methods, which can first use p-methoxybenzyl alcohol as raw material. The p-methoxybenzyl alcohol and chlorinated reagents, such as dichlorosulfoxide, are co-placed in the reaction vessel. The two react at room temperature or slightly warmed state. During this process, the chlorine atom of the dichlorosulfoxide replaces the hydroxyl group of the p-methoxybenzyl alcohol to form 1-chloromethyl-4-methoxybenzene, and sulfur dioxide and hydrogen chloride gas escape at the same time. After the reaction is completed, the product is purified by distillation, extraction, etc. to remove its impurities, and pure 1-chloromethyl-4-methoxybenzene can be obtained.
These two are common methods for synthesizing 1-chloromethyl-4-methoxybenzene. In practice, according to the availability of raw materials, cost considerations, product purity and many other factors, choose the appropriate one and use it.
1-chloromethyl-4-methoxybenzene need to pay attention to when storing and transporting
1 - chloromethyl - 4 - methoxybenzene, Chinese name p-methoxybenzyl chloride, this substance has certain dangers. When storing and transporting, the following rules should be followed:
- ** Storage requirements **:
- ** Choose a suitable location **: Choose a cool, dry and well-ventilated place to store it. This is because the substance is easily decomposed by heat, and a humid environment may also promote chemical reactions. Therefore, keeping it low temperature and dry can ensure the stability of its chemical properties. For example, "Tiangong Kaiwu" said: "If you hide all things, you must choose a cool and dry place to avoid water and fire." The same is true for the storage of methoxybenzyl chloride.
- ** Keep away from contraindications **: It must be stored separately from oxidizing agents and strong bases. Because p-methoxybenzyl chloride encounters oxidizing agents, it is easy to initiate oxidation reactions, and when it encounters strong bases, reactions such as hydrolysis may occur, causing it to deteriorate and may be dangerous. Such as Gu Yun: "Each thing has its own characteristics, and it should not be close to each other." This is the general principle for storing chemicals.
- ** Tight packaging **: The packaging must be tight to ensure that there is no risk of leakage. Generally, it is packed in a sealed container to prevent it from evaporating in the air, which will not only damage the substance, but also pollute the environment, and may endanger the human body. For the Jewish people to hide things, they must be kept tight to prevent air leakage.
- ** Transportation regulations **:
- ** compliance Packaging **: Transportation packaging should meet relevant standards, be durable and leak-proof. The outer packaging should clearly indicate the name of the substance, dangerous characteristics, etc., so that both transporters and regulators can understand. Just like ancient goods, labels must be attached to show their class.
- ** Appropriate car selection **: Transportation vehicles should be selected with corresponding qualifications, and the vehicle should be clean and dry, and there is no residue that may react with the substance. Vehicles should also have good ventilation and fire protection equipment to deal with emergencies.
- ** Special escort **: During the transportation process, professional personnel must be escorted, who are familiar with the properties of the substance and emergency treatment methods. In case of abnormality, measures can be taken quickly to avoid major disasters. In ancient times, important items were also escorted by special personnel, especially in the transportation of dangerous chemicals today.
- ** Storage requirements **:
- ** Choose a suitable location **: Choose a cool, dry and well-ventilated place to store it. This is because the substance is easily decomposed by heat, and a humid environment may also promote chemical reactions. Therefore, keeping it low temperature and dry can ensure the stability of its chemical properties. For example, "Tiangong Kaiwu" said: "If you hide all things, you must choose a cool and dry place to avoid water and fire." The same is true for the storage of methoxybenzyl chloride.
- ** Keep away from contraindications **: It must be stored separately from oxidizing agents and strong bases. Because p-methoxybenzyl chloride encounters oxidizing agents, it is easy to initiate oxidation reactions, and when it encounters strong bases, reactions such as hydrolysis may occur, causing it to deteriorate and may be dangerous. Such as Gu Yun: "Each thing has its own characteristics, and it should not be close to each other." This is the general principle for storing chemicals.
- ** Tight packaging **: The packaging must be tight to ensure that there is no risk of leakage. Generally, it is packed in a sealed container to prevent it from evaporating in the air, which will not only damage the substance, but also pollute the environment, and may endanger the human body. For the Jewish people to hide things, they must be kept tight to prevent air leakage.
- ** Transportation regulations **:
- ** compliance Packaging **: Transportation packaging should meet relevant standards, be durable and leak-proof. The outer packaging should clearly indicate the name of the substance, dangerous characteristics, etc., so that both transporters and regulators can understand. Just like ancient goods, labels must be attached to show their class.
- ** Appropriate car selection **: Transportation vehicles should be selected with corresponding qualifications, and the vehicle should be clean and dry, and there is no residue that may react with the substance. Vehicles should also have good ventilation and fire protection equipment to deal with emergencies.
- ** Special escort **: During the transportation process, professional personnel must be escorted, who are familiar with the properties of the substance and emergency treatment methods. In case of abnormality, measures can be taken quickly to avoid major disasters. In ancient times, important items were also escorted by special personnel, especially in the transportation of dangerous chemicals today.
1-chloromethyl-4-methoxybenzene impact on the environment and people
1-Chloromethyl-4-methoxybenzene, this is an organic compound, and its impact on the environment and human body cannot be underestimated.
In terms of the environment, if it is released into the environment, there will be many conditions. It may be difficult to degrade rapidly in the soil, and the chemical stability is enhanced due to the presence of chlorine atoms in the structure. This may cause it to remain in the soil, which in turn affects the soil ecosystem. The microbial community in the soil may be disturbed by it, and various biochemical processes that microorganisms participate in, such as decomposition of organic matter and nutrient cycling, will also be affected. In water bodies, due to its hydrophobicity, or adsorption on suspended particulate matter, it settles to the bottom sediment, posing a long-term threat to aquatic organisms. If fish and plankton in water are exposed to this compound, they may be poisoned, affecting their growth, reproduction, and even causing their death, thereby destroying the balance of aquatic ecology.
It is also harmful to the human body. Inhalation through the respiratory tract can stimulate the mucosa of the respiratory tract, causing symptoms such as cough and asthma. Long-term inhalation may cause serious damage to the lungs, increasing the risk of lung diseases. Through skin contact, it can penetrate the skin barrier and enter the human blood circulation. Because it is fat-soluble, it is easy to accumulate in fat tissue. This compound may be potentially carcinogenic. Long-term exposure will increase the risk of cancer. It may also affect the human nervous system, causing symptoms such as dizziness, fatigue, and memory loss, and interfering with the normal function of the nervous system. In conclusion, 1-chloromethyl-4-methoxybenzene has many negative effects on the environment and humans, and it needs to be treated with caution.
In terms of the environment, if it is released into the environment, there will be many conditions. It may be difficult to degrade rapidly in the soil, and the chemical stability is enhanced due to the presence of chlorine atoms in the structure. This may cause it to remain in the soil, which in turn affects the soil ecosystem. The microbial community in the soil may be disturbed by it, and various biochemical processes that microorganisms participate in, such as decomposition of organic matter and nutrient cycling, will also be affected. In water bodies, due to its hydrophobicity, or adsorption on suspended particulate matter, it settles to the bottom sediment, posing a long-term threat to aquatic organisms. If fish and plankton in water are exposed to this compound, they may be poisoned, affecting their growth, reproduction, and even causing their death, thereby destroying the balance of aquatic ecology.
It is also harmful to the human body. Inhalation through the respiratory tract can stimulate the mucosa of the respiratory tract, causing symptoms such as cough and asthma. Long-term inhalation may cause serious damage to the lungs, increasing the risk of lung diseases. Through skin contact, it can penetrate the skin barrier and enter the human blood circulation. Because it is fat-soluble, it is easy to accumulate in fat tissue. This compound may be potentially carcinogenic. Long-term exposure will increase the risk of cancer. It may also affect the human nervous system, causing symptoms such as dizziness, fatigue, and memory loss, and interfering with the normal function of the nervous system. In conclusion, 1-chloromethyl-4-methoxybenzene has many negative effects on the environment and humans, and it needs to be treated with caution.
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