Linshang Chemical
PRODUCTS
1-(Dichloromethyl)-2-Fluorobenzene
|
HS Code |
413661 |
| Chemical Formula | C7H5Cl2F |
| Molecular Weight | 179.019 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 192 - 194 °C |
| Density | 1.358 g/mL at 25 °C |
| Solubility In Water | Insoluble |
| Flash Point | 78 °C |
| Refractive Index | 1.5255 - 1.5275 |
As an accredited 1-(Dichloromethyl)-2-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1-(dichloromethyl)-2-fluorobenzene packaged in a sealed, corrosion - resistant bottle. |
| Storage | 1-(Dichloromethyl)-2-fluorobenzene should be stored in a cool, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly - sealed container to prevent leakage and evaporation. As it is a chemical, store it separately from incompatible substances like oxidizing agents, reducing agents, and bases to avoid potential reactions. Ensure storage areas comply with safety regulations. |
| Shipping | 1-(Dichloromethyl)-2 -fluorobenzene is shipped in tightly sealed, corrosion - resistant containers. Shipment follows strict hazardous chemical regulations, ensuring proper labeling, documentation, and transport in suitable vehicles to prevent leakage and risks. |
Competitive 1-(Dichloromethyl)-2-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-(Dichloromethyl)-2-Fluorobenzene in China?
As a trusted 1-(Dichloromethyl)-2-Fluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-(Dichloromethyl)-2-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 1- (dichloromethyl) -2-fluorobenzene?
Dimethyl ether, also known as methoxyethane, has the following physical properties:
Dimethyl ether appears as a colorless, ether-like odor flammable liquid at room temperature and pressure. Its boiling point is relatively low, about 10.8 ° C, which allows it to be converted into a gaseous state at milder temperatures. The lower boiling point determines that it has a strong volatility. Once exposed to air, it can quickly change from a liquid state to a gaseous state and evaporate.
From the melting point, the melting point of dimethyl ether is about -113.2 ° C, which indicates that it solidifies at very low temperatures and exists in liquid form in general room temperature environments and common low temperature environments.
In terms of density, its density is smaller than that of water, about 0.661 g/cm ³, so when dimethyl ether comes into contact with water, it will float above the water surface and form an obvious stratification phenomenon with water.
Dimethyl ether is slightly soluble in water, which is determined by the characteristics of its molecular structure. It belongs to a non-polar molecule, while water is a polar molecule. According to the principle of similarity miscibility, dimethyl ether has limited solubility in water. However, it is miscible in most organic solvents, such as ethanol, acetone, chloroform, etc., and can dissolve with these organic solvents in any ratio. This property makes it widely used as a solvent in organic synthesis and other fields.
In addition, the vapor relative density of dimethyl ether (air = 1) is about 2.07, which means that its vapor is heavier than air, and after leakage in the air, the vapor will spread close to the ground, increasing the safety risk such as fire, because it is flammable and can form explosive mixtures with air.
Dimethyl ether appears as a colorless, ether-like odor flammable liquid at room temperature and pressure. Its boiling point is relatively low, about 10.8 ° C, which allows it to be converted into a gaseous state at milder temperatures. The lower boiling point determines that it has a strong volatility. Once exposed to air, it can quickly change from a liquid state to a gaseous state and evaporate.
From the melting point, the melting point of dimethyl ether is about -113.2 ° C, which indicates that it solidifies at very low temperatures and exists in liquid form in general room temperature environments and common low temperature environments.
In terms of density, its density is smaller than that of water, about 0.661 g/cm ³, so when dimethyl ether comes into contact with water, it will float above the water surface and form an obvious stratification phenomenon with water.
Dimethyl ether is slightly soluble in water, which is determined by the characteristics of its molecular structure. It belongs to a non-polar molecule, while water is a polar molecule. According to the principle of similarity miscibility, dimethyl ether has limited solubility in water. However, it is miscible in most organic solvents, such as ethanol, acetone, chloroform, etc., and can dissolve with these organic solvents in any ratio. This property makes it widely used as a solvent in organic synthesis and other fields.
In addition, the vapor relative density of dimethyl ether (air = 1) is about 2.07, which means that its vapor is heavier than air, and after leakage in the air, the vapor will spread close to the ground, increasing the safety risk such as fire, because it is flammable and can form explosive mixtures with air.
What are the chemical properties of 1- (dichloromethyl) -2-fluorobenzene?
Dioxyethyl is unique in the field of chemical industry. It is active and can involve many reactions. It is often a key agent in organic synthesis.
Dioxyethyl has electrophilic properties and is easy to combine with electron-rich bodies. It can form a special ring structure in cyclization reactions. This structure is useful in drug creation and material research and development. And the stability of dioxyethyl is also an important feature. Under specific conditions, it can maintain the integrity of the structure and not easily decompose, so that the reactions involved are orderly.
As for ether, it is a colorless and transparent liquid with a special smell and a slightly sweet taste. The boiling point of ether is quite low, only about 34.6 ° C, which makes it volatile and can quickly turn into a gaseous state at room temperature.
The solubility of ether is particularly considerable, and it can be miscible with alcohol, benzene, chloroform and other organic solvents, but slightly soluble in water. In chemical experiments, ether is often used as an extractant because it can efficiently separate specific components in the mixture.
In addition, ether is flammable, and its vapor is mixed with air, which can form an explosive mixed gas. In case of open flame and hot topic, it is very easy to burn and explode. Therefore, extreme caution and strict safety regulations are required when storing and using it. In the past, ether was also used as an anesthetic for surgery, but now it has been gradually replaced by other substances because of its certain toxicity and side effects.
In short, dioxyethyl and ether have their own unique chemical properties, and they have shown important functions in different fields. However, when using it, it is necessary to know its properties in detail to ensure safety.
Dioxyethyl has electrophilic properties and is easy to combine with electron-rich bodies. It can form a special ring structure in cyclization reactions. This structure is useful in drug creation and material research and development. And the stability of dioxyethyl is also an important feature. Under specific conditions, it can maintain the integrity of the structure and not easily decompose, so that the reactions involved are orderly.
As for ether, it is a colorless and transparent liquid with a special smell and a slightly sweet taste. The boiling point of ether is quite low, only about 34.6 ° C, which makes it volatile and can quickly turn into a gaseous state at room temperature.
The solubility of ether is particularly considerable, and it can be miscible with alcohol, benzene, chloroform and other organic solvents, but slightly soluble in water. In chemical experiments, ether is often used as an extractant because it can efficiently separate specific components in the mixture.
In addition, ether is flammable, and its vapor is mixed with air, which can form an explosive mixed gas. In case of open flame and hot topic, it is very easy to burn and explode. Therefore, extreme caution and strict safety regulations are required when storing and using it. In the past, ether was also used as an anesthetic for surgery, but now it has been gradually replaced by other substances because of its certain toxicity and side effects.
In short, dioxyethyl and ether have their own unique chemical properties, and they have shown important functions in different fields. However, when using it, it is necessary to know its properties in detail to ensure safety.
In what fields is 1- (dichloromethyl) -2-fluorobenzene used?
I look at you and ask, one is "1 - (dioxy methyl) ", this expression is not detailed exactly what it refers to, or in the field of chemistry, but only for this phrase, it is difficult to understand what it wants, or it is related to chemical calculations, reaction steps, etc. Unfortunately, there is a lack of information, and it is difficult to discuss in depth.
The second question is the application field of bromothymol blue. Bromothymol blue is an acid-base indicator, and it is also used in biological and chemical experiments. In biology, it is often used to detect the production of carbon dioxide. If organisms release carbon dioxide through respiration, bromothymol blue aqueous solution turns from blue to green and then turns yellow, which can help to detect the respiration status of cells. For example, in the plant respiration experiment, the plant is sealed in a container and the bromothymol blue solution is built. After a certain period of time, the color of the solution changes, and it can be known whether the plant produces carbon dioxide.
In the field of chemical analysis, because it is sensitive to pH changes, it can indicate the change of the acid-base degree of the solution. In some titration experiments, according to its color change, the reaction endpoint can be determined, and the solution composition and concentration can be analyzed. And in environmental monitoring, it can also be used to detect changes in the pH of water bodies to check the water quality. If the pH of water is abnormal due to pollution, bromothymol blue can be visualized to provide a reference for water quality assessment.
The second question is the application field of bromothymol blue. Bromothymol blue is an acid-base indicator, and it is also used in biological and chemical experiments. In biology, it is often used to detect the production of carbon dioxide. If organisms release carbon dioxide through respiration, bromothymol blue aqueous solution turns from blue to green and then turns yellow, which can help to detect the respiration status of cells. For example, in the plant respiration experiment, the plant is sealed in a container and the bromothymol blue solution is built. After a certain period of time, the color of the solution changes, and it can be known whether the plant produces carbon dioxide.
In the field of chemical analysis, because it is sensitive to pH changes, it can indicate the change of the acid-base degree of the solution. In some titration experiments, according to its color change, the reaction endpoint can be determined, and the solution composition and concentration can be analyzed. And in environmental monitoring, it can also be used to detect changes in the pH of water bodies to check the water quality. If the pH of water is abnormal due to pollution, bromothymol blue can be visualized to provide a reference for water quality assessment.
What are the synthesis methods of 1- (dichloromethyl) -2-fluorobenzene?
The synthesis method of 1- (dimethyl) -2 -chlorobenzene is as follows:
First, it can be prepared by oxidation of o-chlorotoluene. Under the action of suitable oxidants, such as potassium permanganate, the methyl group of o-chlorotoluene can be oxidized to carboxyl group to obtain o-chlorobenzoic acid. Then the o-chlorobenzoic acid converts the carboxyl group into chloromethyl group under specific conditions, such as reacting with a halogenating agent, to obtain 1- (dimethyl) -2 -chlorobenzene. The raw materials for this method are relatively easy to obtain, but the oxidation step requires fine control of the reaction conditions, otherwise it is easy to cause side reactions such as excessive oxidation.
Second, benzene is used as the starting material, and the chlorination reaction is carried out Under the catalysis of suitable catalysts, such as ferric chloride, benzene reacts with chlorine gas to obtain chlorobenzene. Then chlorobenzene reacts with methylation reagents, such as halogenated methane, in the presence of bases and phase transfer catalysts, nucleophilic substitution reactions occur, and methyl groups are introduced into the benzene ring. This process requires attention to the position selectivity of the reaction. Due to the existence of o, m, and p isomers in the substitution reaction of chlorobenzene, it is necessary to select suitable reaction conditions and catalysts to improve the yield of the target product 1- (dimethyl) - 2 - chlorobenzene.
Third, it can be synthesized by the Grignard reagent method. First, the Grignard reagent of chlorobenzene is prepared, and the chlorobenzene is reacted Then phenyl magnesium chloride is reacted with halogenated methyl reagent, methyl is introduced, and then the target product can be obtained by subsequent treatment. This method requires strict reaction conditions, requires anhydrous and anaerobic environment, and the operation is relatively complicated, but it has high flexibility and selectivity for the construction of specific structures.
First, it can be prepared by oxidation of o-chlorotoluene. Under the action of suitable oxidants, such as potassium permanganate, the methyl group of o-chlorotoluene can be oxidized to carboxyl group to obtain o-chlorobenzoic acid. Then the o-chlorobenzoic acid converts the carboxyl group into chloromethyl group under specific conditions, such as reacting with a halogenating agent, to obtain 1- (dimethyl) -2 -chlorobenzene. The raw materials for this method are relatively easy to obtain, but the oxidation step requires fine control of the reaction conditions, otherwise it is easy to cause side reactions such as excessive oxidation.
Second, benzene is used as the starting material, and the chlorination reaction is carried out Under the catalysis of suitable catalysts, such as ferric chloride, benzene reacts with chlorine gas to obtain chlorobenzene. Then chlorobenzene reacts with methylation reagents, such as halogenated methane, in the presence of bases and phase transfer catalysts, nucleophilic substitution reactions occur, and methyl groups are introduced into the benzene ring. This process requires attention to the position selectivity of the reaction. Due to the existence of o, m, and p isomers in the substitution reaction of chlorobenzene, it is necessary to select suitable reaction conditions and catalysts to improve the yield of the target product 1- (dimethyl) - 2 - chlorobenzene.
Third, it can be synthesized by the Grignard reagent method. First, the Grignard reagent of chlorobenzene is prepared, and the chlorobenzene is reacted Then phenyl magnesium chloride is reacted with halogenated methyl reagent, methyl is introduced, and then the target product can be obtained by subsequent treatment. This method requires strict reaction conditions, requires anhydrous and anaerobic environment, and the operation is relatively complicated, but it has high flexibility and selectivity for the construction of specific structures.
What are the precautions in the production of 1- (dichloromethyl) -2-fluorobenzene?
The production process of dioxybenzyl-2-chloronaphthalene requires attention to many key matters.
First, the selection of raw materials must be carefully selected. Dioxybenzyl and chloronaphthalene are the main raw materials, and their purity and quality have a profound impact on the final product. If there are too many impurities in the raw materials, it will not only reduce the purity of the product, but also may cause side reactions, resulting in a decline in yield. Therefore, when purchasing, it is necessary to choose a reputable supplier, strictly control the quality of the raw materials, and conduct detailed testing after receiving the goods.
Second, the control of the reaction conditions is extremely critical. In terms of temperature, this reaction is quite sensitive to temperature changes. If the temperature is too high, the reaction rate will be accelerated, but the probability of side reactions will also increase greatly, and many impurities may be formed; if the temperature is too low, the reaction rate will be slow, it will take a long time, and may even cause the reaction to be incomplete. Pressure cannot be ignored. Appropriate pressure can promote the smooth progress of the reaction in the desired direction. Improper pressure may affect the equilibrium and rate of the reaction. Therefore, during the reaction, precise temperature and pressure control equipment should be used to maintain the stability of the reaction conditions.
Third, the use of catalysts needs to be cautious. A suitable catalyst can significantly improve the reaction rate and selectivity. However, the type, dosage and timing of catalyst addition all need to be precisely controlled. The catalytic effect of different catalysts on the reaction varies greatly. If the dosage is too small, the catalytic effect is not obvious; if the dosage is too large, it will not only waste resources, but also cause other problems. The timing of addition is also crucial. Adding too early or too late may affect the reaction process.
Fourth, safety protection measures must be in place. Dioxy benzyl and chloronaphthalene may have certain toxicity and danger. During the production operation, the operator must strictly wear protective equipment, such as protective clothing, gloves, protective glasses and gas masks, to prevent contact with harmful substances. At the same time, the production site should have good ventilation facilities, timely discharge of harmful gases, and complete emergency treatment equipment and plans should be equipped to deal with emergencies.
Fifth, product separation and purification should not be underestimated. After the reaction, the product is often mixed with impurities such as unreacted raw materials, by-products and catalysts. Proper separation and purification methods must be used, such as distillation, extraction, crystallization, etc., to obtain high-purity products. In this process, appropriate methods should be selected according to the characteristics of the product and impurities, and operating conditions should be strictly controlled to ensure product quality standards.
First, the selection of raw materials must be carefully selected. Dioxybenzyl and chloronaphthalene are the main raw materials, and their purity and quality have a profound impact on the final product. If there are too many impurities in the raw materials, it will not only reduce the purity of the product, but also may cause side reactions, resulting in a decline in yield. Therefore, when purchasing, it is necessary to choose a reputable supplier, strictly control the quality of the raw materials, and conduct detailed testing after receiving the goods.
Second, the control of the reaction conditions is extremely critical. In terms of temperature, this reaction is quite sensitive to temperature changes. If the temperature is too high, the reaction rate will be accelerated, but the probability of side reactions will also increase greatly, and many impurities may be formed; if the temperature is too low, the reaction rate will be slow, it will take a long time, and may even cause the reaction to be incomplete. Pressure cannot be ignored. Appropriate pressure can promote the smooth progress of the reaction in the desired direction. Improper pressure may affect the equilibrium and rate of the reaction. Therefore, during the reaction, precise temperature and pressure control equipment should be used to maintain the stability of the reaction conditions.
Third, the use of catalysts needs to be cautious. A suitable catalyst can significantly improve the reaction rate and selectivity. However, the type, dosage and timing of catalyst addition all need to be precisely controlled. The catalytic effect of different catalysts on the reaction varies greatly. If the dosage is too small, the catalytic effect is not obvious; if the dosage is too large, it will not only waste resources, but also cause other problems. The timing of addition is also crucial. Adding too early or too late may affect the reaction process.
Fourth, safety protection measures must be in place. Dioxy benzyl and chloronaphthalene may have certain toxicity and danger. During the production operation, the operator must strictly wear protective equipment, such as protective clothing, gloves, protective glasses and gas masks, to prevent contact with harmful substances. At the same time, the production site should have good ventilation facilities, timely discharge of harmful gases, and complete emergency treatment equipment and plans should be equipped to deal with emergencies.
Fifth, product separation and purification should not be underestimated. After the reaction, the product is often mixed with impurities such as unreacted raw materials, by-products and catalysts. Proper separation and purification methods must be used, such as distillation, extraction, crystallization, etc., to obtain high-purity products. In this process, appropriate methods should be selected according to the characteristics of the product and impurities, and operating conditions should be strictly controlled to ensure product quality standards.
Scan to WhatsApp
