Linshang Chemical
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1-(Dichloromethyl)-3-Fluorobenzene
|
HS Code |
698265 |
| Chemical Formula | C7H5Cl2F |
| Molar Mass | 181.02 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 195 - 197 °C |
| Density | 1.36 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | 81 °C |
| Refractive Index | 1.520 - 1.522 |
As an accredited 1-(Dichloromethyl)-3-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - (Dichloromethyl)-3 - fluorobenzene in 500 - mL glass bottles, 10 bottles per carton. |
| Storage | 1-(Dichloromethyl)-3-fluorobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames due to its flammability risk. Keep it in a tightly sealed container to prevent vapor leakage. Store separately from oxidizing agents and reactive substances to avoid potential chemical reactions. Label containers clearly for easy identification and safety handling. |
| Shipping | 1-(Dichloromethyl)-3-fluorobenzene is shipped in specialized, well - sealed containers. It follows strict chemical shipping regulations to prevent leakage, ensuring safety during transit due to its potentially hazardous nature. |
Competitive 1-(Dichloromethyl)-3-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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What are the main uses of 1- (dichloromethyl) -3-fluorobenzene?
1 - (dimethyl) - 3 - chlorobenzene, which is an organic compound. It has a wide range of main uses and is a key intermediate in the synthesis of many drugs in the field of medicine. For example, when synthesizing antibacterial drugs with specific therapeutic effects, 1 - (dimethyl) - 3 - chlorobenzene can be converted into a key structural part of the drug molecule through a series of chemical reactions, giving the drug antibacterial activity.
It also plays an important role in the field of materials science. It can be used as a starting material for the synthesis of special polymer materials. By polymerizing with other monomers, polymers with special properties can be prepared, such as materials with good thermal stability and mechanical properties, which can be used in aerospace, automobile manufacturing and other industries that require strict material properties.
In the field of pesticides, 1 - (dimethyl) - 3 - chlorobenzene is an important raw material for the synthesis of some high-efficiency and low-toxicity pesticides. After reasonable chemical modification and reaction, pesticide products that target specific pests and have little impact on the environment can be synthesized, contributing to the green and sustainable development of agriculture.
In addition, in the fine chemical industry, it is often used to synthesize various fine chemicals, such as fragrances, dyes, etc. Giving these products unique properties and functions, such as in dye synthesis, can improve the color and fastness of dyes, and meet the diverse needs of fine chemicals in different fields.
It also plays an important role in the field of materials science. It can be used as a starting material for the synthesis of special polymer materials. By polymerizing with other monomers, polymers with special properties can be prepared, such as materials with good thermal stability and mechanical properties, which can be used in aerospace, automobile manufacturing and other industries that require strict material properties.
In the field of pesticides, 1 - (dimethyl) - 3 - chlorobenzene is an important raw material for the synthesis of some high-efficiency and low-toxicity pesticides. After reasonable chemical modification and reaction, pesticide products that target specific pests and have little impact on the environment can be synthesized, contributing to the green and sustainable development of agriculture.
In addition, in the fine chemical industry, it is often used to synthesize various fine chemicals, such as fragrances, dyes, etc. Giving these products unique properties and functions, such as in dye synthesis, can improve the color and fastness of dyes, and meet the diverse needs of fine chemicals in different fields.
What are the physical properties of 1- (dichloromethyl) -3-fluorobenzene?
1 - (dioxy methyl) - 3 - deuterium benzene, its physical properties are as follows:
dioxy methyl, its structure contains a combination of dioxy and methyl. Usually has a certain polarity, due to the strong electronegativity of oxygen atoms, it can cause uneven distribution of charge in molecules. In terms of solubility, because of its polarity, it has a certain affinity for some polar solvents such as alcohols, and can be moderately dissolved in them. Its boiling point and melting point are also affected by intermolecular forces. Due to the existence of polarity, the intermolecular forces are strong, resulting in a relatively high boiling point. However, the exact value depends on the specific structure and surrounding chemical environment.
As for 3 - deuterium benzene, deuterium is an isotope of hydrogen. Benzene is a planar cyclic structure with high symmetry and is a non-polar molecule. When the hydrogen at the third position of the benzene ring is replaced by deuterium, although the chemical properties of deuterium and hydrogen are similar, the molecular weight increases because the mass of deuterium is greater than that of hydrogen. This mass change has many effects on its physical properties, such as a slight increase in density compared with benzene. In terms of melting and boiling point, due to the increase in molecular weight and the increase in intermolecular dispersion force, the melting and boiling point will also increase slightly compared with benzene. At the same time, since deuterium substitution does not significantly change the electron cloud distribution of the benzene ring, its solubility is still similar to that of benzene, and it is difficult to dissolve in polar solvents such as water, but easily soluble in non-polar or weakly polar organic solvents such as carbon tet
From a comprehensive perspective, 1- (dioxy methyl) -3 -deuterium benzene has both the polarity-related properties of dioxy methyl and the physical properties caused by the mass change after deuterium substitution of benzene. The application in chemical industry, scientific research and other fields needs to be properly considered according to its unique physical properties.
dioxy methyl, its structure contains a combination of dioxy and methyl. Usually has a certain polarity, due to the strong electronegativity of oxygen atoms, it can cause uneven distribution of charge in molecules. In terms of solubility, because of its polarity, it has a certain affinity for some polar solvents such as alcohols, and can be moderately dissolved in them. Its boiling point and melting point are also affected by intermolecular forces. Due to the existence of polarity, the intermolecular forces are strong, resulting in a relatively high boiling point. However, the exact value depends on the specific structure and surrounding chemical environment.
As for 3 - deuterium benzene, deuterium is an isotope of hydrogen. Benzene is a planar cyclic structure with high symmetry and is a non-polar molecule. When the hydrogen at the third position of the benzene ring is replaced by deuterium, although the chemical properties of deuterium and hydrogen are similar, the molecular weight increases because the mass of deuterium is greater than that of hydrogen. This mass change has many effects on its physical properties, such as a slight increase in density compared with benzene. In terms of melting and boiling point, due to the increase in molecular weight and the increase in intermolecular dispersion force, the melting and boiling point will also increase slightly compared with benzene. At the same time, since deuterium substitution does not significantly change the electron cloud distribution of the benzene ring, its solubility is still similar to that of benzene, and it is difficult to dissolve in polar solvents such as water, but easily soluble in non-polar or weakly polar organic solvents such as carbon tet
From a comprehensive perspective, 1- (dioxy methyl) -3 -deuterium benzene has both the polarity-related properties of dioxy methyl and the physical properties caused by the mass change after deuterium substitution of benzene. The application in chemical industry, scientific research and other fields needs to be properly considered according to its unique physical properties.
Is 1- (dichloromethyl) -3-fluorobenzene chemically stable?
1 - (dioxomethyl) - 3 - chloronaphthalene This compound has relatively stable chemical properties. From a structural point of view, dioxomethyl is connected to chloronaphthalene. In dioxomethyl, the oxygen atom has a certain electronegativity, which is connected to the methyl group and can affect the electron cloud distribution of the whole molecule. The presence of this substituent can enhance the stability of the molecule. Due to the interaction between the lone pair electrons of the oxygen atom and the surrounding atoms, the part of the structure is not prone to fracture or reaction.
And the 3 - chloronaphthalene part, the naphthalene ring itself has a conjugated system, and this conjugated structure endows the molecule with a certain stability. The chlorine atom is substituted on the naphthalene ring, and the electron-withdrawing effect of the chlorine atom will affect the electron cloud density of the naphthalene ring, which in turn affects the chemical activity of the whole molecule. But in general, the conjugated system of the naphthalene ring can disperse the electron-withdrawing action of the chlorine atom to a certain extent, so that the stability of the whole compound can be maintained.
In general chemical environment, the compound will not easily decompose or rearrange spontaneously. Its chemical bond energy is relatively high, and to make the compound react, specific reaction conditions, such as high temperature, specific catalysts, and suitable reaction reagents, are usually required. These conditions can provide enough energy to overcome the energy barrier of the reaction and promote the chemical reaction of the compound. Therefore, 1 - (dioxy methyl) -3 -chloronaphthalene is chemically stable under normal conditions.
And the 3 - chloronaphthalene part, the naphthalene ring itself has a conjugated system, and this conjugated structure endows the molecule with a certain stability. The chlorine atom is substituted on the naphthalene ring, and the electron-withdrawing effect of the chlorine atom will affect the electron cloud density of the naphthalene ring, which in turn affects the chemical activity of the whole molecule. But in general, the conjugated system of the naphthalene ring can disperse the electron-withdrawing action of the chlorine atom to a certain extent, so that the stability of the whole compound can be maintained.
In general chemical environment, the compound will not easily decompose or rearrange spontaneously. Its chemical bond energy is relatively high, and to make the compound react, specific reaction conditions, such as high temperature, specific catalysts, and suitable reaction reagents, are usually required. These conditions can provide enough energy to overcome the energy barrier of the reaction and promote the chemical reaction of the compound. Therefore, 1 - (dioxy methyl) -3 -chloronaphthalene is chemically stable under normal conditions.
What are the synthesis methods of 1- (dichloromethyl) -3-fluorobenzene?
To prepare 1 - (dioxy methyl) - 3 - chloropyridine, there are many ways to synthesize it, which are described in detail below.
First, pyridine can be used as the starting material. First, pyridine is reacted with a specific reagent under suitable conditions to introduce a specific substituent, and then chlorine atoms are introduced at the designated position through halogenation reaction, and then through a series of carefully designed reaction steps, the dioxy methyl structure is ingeniously constructed. In this process, the control of the conditions of each step of the reaction is extremely critical, such as the reaction temperature, reaction time, and the proportion of reactants. All need to be precisely regulated to ensure that the reaction proceeds smoothly in the expected direction and improve the yield and purity of the target product.
Second, the pyridine derivative containing specific substituents can also be used as the starting material. Using its existing substituents, according to the principles and methods of organic synthesis, the molecular structure can be gradually modified through suitable chemical reactions. For example, by means of nucleophilic substitution reactions, oxidation reactions and other classic organic reaction types, the conversion to 1- (dioxomethyl) -3-chloropyridine can be achieved in an orderly manner. In this path, the choice of the starting material needs to be carefully considered, and its structural characteristics will directly affect the difficulty of the subsequent reaction and the quality of the product.
Furthermore, a multi-step tandem reaction strategy can also be used. Multiple simple chemical reactions are cleverly connected in series, and different types of reactions occur in sequence in the same reaction system, thus avoiding cumbersome intermediate separation and purification steps. However, this method requires extremely high synergy of reaction conditions, and requires in-depth study of the interaction between each reaction and careful optimization of reaction parameters to ensure that the whole series reaction proceeds efficiently and stably, and finally the target product 1 - (dioxymethyl) - 3 - chloropyridine is successfully obtained.
First, pyridine can be used as the starting material. First, pyridine is reacted with a specific reagent under suitable conditions to introduce a specific substituent, and then chlorine atoms are introduced at the designated position through halogenation reaction, and then through a series of carefully designed reaction steps, the dioxy methyl structure is ingeniously constructed. In this process, the control of the conditions of each step of the reaction is extremely critical, such as the reaction temperature, reaction time, and the proportion of reactants. All need to be precisely regulated to ensure that the reaction proceeds smoothly in the expected direction and improve the yield and purity of the target product.
Second, the pyridine derivative containing specific substituents can also be used as the starting material. Using its existing substituents, according to the principles and methods of organic synthesis, the molecular structure can be gradually modified through suitable chemical reactions. For example, by means of nucleophilic substitution reactions, oxidation reactions and other classic organic reaction types, the conversion to 1- (dioxomethyl) -3-chloropyridine can be achieved in an orderly manner. In this path, the choice of the starting material needs to be carefully considered, and its structural characteristics will directly affect the difficulty of the subsequent reaction and the quality of the product.
Furthermore, a multi-step tandem reaction strategy can also be used. Multiple simple chemical reactions are cleverly connected in series, and different types of reactions occur in sequence in the same reaction system, thus avoiding cumbersome intermediate separation and purification steps. However, this method requires extremely high synergy of reaction conditions, and requires in-depth study of the interaction between each reaction and careful optimization of reaction parameters to ensure that the whole series reaction proceeds efficiently and stably, and finally the target product 1 - (dioxymethyl) - 3 - chloropyridine is successfully obtained.
What are the precautions for storing and transporting 1- (dichloromethyl) -3-fluorobenzene?
Dioxomethyl-3-chlorobenzene should be paid attention to in storage and transportation, and it is related to the safety and quality of the goods, and must not be ignored.
The first safety protection. This dioxomethyl-3-chlorobenzene may be toxic, corrosive, flammable, etc. When storing, it must be selected in a suitable place, away from fire and heat sources, and well ventilated. Operators, in front of suitable protective equipment, such as gas masks, anti-corrosive gloves, protective clothing, etc., to prevent contact, lung inhalation, and physical injury.
Times are storage conditions. Store in a cool, dry place away from direct light. Due to light, heat or its qualitative change, it reduces its purity, or causes a dangerous situation. And it is stored separately from oxidants, alkalis, etc., to prevent reaction. If stacking, it is also necessary to fit, so as to ventilate and dissipate heat to avoid danger caused by accumulated heat.
Further transportation regulations. During transportation, choose a suitable vehicle to ensure that it is well sealed and there is no risk of leakage. According to its nature, mark the corresponding warning mark on the vehicle. During the journey, the driver should be careful to avoid shocks, collisions, and high temperatures. When stopping, choose a safe place, far away from people and places of fire.
There is also inspection and monitoring. During the storage period, regularly check the package to see if there is any leakage; measure the ring, and observe the change of temperature and humidity. If there is any leakage, take measures quickly, surround the site, clear the crowd, and clean up the sewage and waste, according to the regulations.
All these are important for the storage and transportation of dioxy methyl-3-chlorobenzene. Everything is careful according to the regulations, so that it is safe and stable, so as not to suffer from it.
The first safety protection. This dioxomethyl-3-chlorobenzene may be toxic, corrosive, flammable, etc. When storing, it must be selected in a suitable place, away from fire and heat sources, and well ventilated. Operators, in front of suitable protective equipment, such as gas masks, anti-corrosive gloves, protective clothing, etc., to prevent contact, lung inhalation, and physical injury.
Times are storage conditions. Store in a cool, dry place away from direct light. Due to light, heat or its qualitative change, it reduces its purity, or causes a dangerous situation. And it is stored separately from oxidants, alkalis, etc., to prevent reaction. If stacking, it is also necessary to fit, so as to ventilate and dissipate heat to avoid danger caused by accumulated heat.
Further transportation regulations. During transportation, choose a suitable vehicle to ensure that it is well sealed and there is no risk of leakage. According to its nature, mark the corresponding warning mark on the vehicle. During the journey, the driver should be careful to avoid shocks, collisions, and high temperatures. When stopping, choose a safe place, far away from people and places of fire.
There is also inspection and monitoring. During the storage period, regularly check the package to see if there is any leakage; measure the ring, and observe the change of temperature and humidity. If there is any leakage, take measures quickly, surround the site, clear the crowd, and clean up the sewage and waste, according to the regulations.
All these are important for the storage and transportation of dioxy methyl-3-chlorobenzene. Everything is careful according to the regulations, so that it is safe and stable, so as not to suffer from it.
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