Linshang Chemical
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1-Nitro-2-Chloro-5-Fluorobenzene
Linshang Chemical
|
HS Code |
678506 |
| Chemical Formula | C6H3ClFNO2 |
| Molar Mass | 177.545 g/mol |
| Appearance | Typically a solid |
| Physical State At Room Temp | Solid |
| Color | Often colorless to pale yellow |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform, etc., due to its organic nature |
| Odor | May have a pungent, characteristic aromatic odor |
| Stability | Stable under normal conditions but reactive towards strong reducing agents, nucleophiles due to the presence of nitro, chloro and fluoro groups |
As an accredited 1-Nitro-2-Chloro-5-Fluorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 - nitro - 2 - chloro - 5 - fluorobenzene: Packed in 500 - gram bottles for chemical storage. |
| Storage | 1 - nitro - 2 - chloro - 5 - fluorobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store it in a tightly sealed container to prevent leakage and exposure to air and moisture. Label the storage container clearly to avoid misidentification. Use appropriate storage cabinets or areas designated for hazardous chemicals. |
| Shipping | 1 - nitro - 2 - chloro - 5 - fluorobenzene is a chemical. Shipments should be in well - sealed, appropriate containers, compliant with hazardous material regulations. Ensure proper labeling and transportation by approved carriers to avoid risks. |
Competitive 1-Nitro-2-Chloro-5-Fluorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 1-Nitro-2-Chloro-5-Fluorobenzene in China?
As a trusted 1-Nitro-2-Chloro-5-Fluorobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 1-Nitro-2-Chloro-5-Fluorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the main use of 1 - nitro - 2 - chloro - 5 - fluorobenzene
1-Nitro-2-chloro-5-fluorobenzene has a wide range of main uses and is involved in various fields of chemical industry.
First, in the synthesis of medicine, this compound is often a key intermediate. The nitro, chlorine and fluorine atoms attached to the benzene ring can be skillfully converted by chemical methods to lay the foundation for the construction of pharmaceutical active structures. Through a series of reactions, it can be modified and spliced to produce substances with specific pharmacological activities, such as some antibacterial and antiviral pharmaceutical ingredients, which all rely on this as the starting material and are gradually derived.
Second, in the process of pesticide creation, 1-nitro-2-chloro-5-fluorobenzene also plays an important role. Due to its unique chemical structure, it endows the prepared pesticide with specific biological activity and stability. It can be synthesized and integrated into the pesticide molecular system, so that the pesticide can exhibit an efficient inhibitory or killing effect on the target organism, and can be moderately retained in the environment to exert long-lasting efficacy without excessive residue, so as to meet the needs of environmental protection.
Third, in the field of materials science, this compound can participate in the preparation of special materials. Its structural characteristics can affect the electron cloud distribution and spatial configuration of the material, and then affect the physical and chemical properties of the material. For example, in the synthesis of optoelectronic materials, using it as a raw material to build a specific structure can endow the material with unique optical and electrical properties, providing the possibility for the research and development of new optoelectronic materials.
In short, 1-nitro-2-chloro-5-fluorobenzene has an indispensable position in many fields such as medicine, pesticides, and materials due to its unique chemical structure, and has made great contributions to promoting technological innovation and development in various fields.
First, in the synthesis of medicine, this compound is often a key intermediate. The nitro, chlorine and fluorine atoms attached to the benzene ring can be skillfully converted by chemical methods to lay the foundation for the construction of pharmaceutical active structures. Through a series of reactions, it can be modified and spliced to produce substances with specific pharmacological activities, such as some antibacterial and antiviral pharmaceutical ingredients, which all rely on this as the starting material and are gradually derived.
Second, in the process of pesticide creation, 1-nitro-2-chloro-5-fluorobenzene also plays an important role. Due to its unique chemical structure, it endows the prepared pesticide with specific biological activity and stability. It can be synthesized and integrated into the pesticide molecular system, so that the pesticide can exhibit an efficient inhibitory or killing effect on the target organism, and can be moderately retained in the environment to exert long-lasting efficacy without excessive residue, so as to meet the needs of environmental protection.
Third, in the field of materials science, this compound can participate in the preparation of special materials. Its structural characteristics can affect the electron cloud distribution and spatial configuration of the material, and then affect the physical and chemical properties of the material. For example, in the synthesis of optoelectronic materials, using it as a raw material to build a specific structure can endow the material with unique optical and electrical properties, providing the possibility for the research and development of new optoelectronic materials.
In short, 1-nitro-2-chloro-5-fluorobenzene has an indispensable position in many fields such as medicine, pesticides, and materials due to its unique chemical structure, and has made great contributions to promoting technological innovation and development in various fields.
What are the physical properties of 1 - nitro - 2 - chloro - 5 - fluorobenzene
1-Nitro-2-chloro-5-fluorobenzene is one of the organic compounds. Its physical properties are particularly important, and it is related to the behavior of this substance in various situations.
First of all, its appearance, 1-nitro-2-chloro-5-fluorobenzene is usually a colorless to light yellow liquid, or a crystalline solid, depending on the temperature and environment. This appearance characteristic can be used as an important basis for preliminary identification and determination of its purity.
The melting point of this substance is about a specific range. The melting point is the critical temperature at which the substance changes from solid to liquid state. The melting point of 1-nitro-2-chloro-5-fluorobenzene has a great influence on its separation, purification and storage operations. If the temperature is higher than the melting point, it is in a liquid state; if it is lower than the melting point, it is in a solid state. Mastering the melting point helps to precisely control its physical state to meet different needs.
Besides the boiling point, the boiling point is the temperature at which a liquid turns into a gas. The boiling point of 1-nitro-2-chloro-5-fluorobenzene also has a specific value. The boiling point is closely related to the intermolecular forces. By understanding the boiling point, it can be effectively separated from other substances in separation procedures such as distillation to ensure its purity.
Solubility is also a key property. 1-nitro-2-chloro-5-fluorobenzene has a certain solubility in organic solvents, such as certain aromatics, halogenated hydrocarbons, etc., but has little solubility in water. This difference in solubility can be used to selectively separate and extract the substance during chemical synthesis, extraction, etc.
In terms of density, 1-nitro-2-chloro-5-fluorobenzene has a specific density value. Density can be used to measure the mass of a substance per unit volume, and is an important consideration when storing, transporting, and measuring related chemical reactions.
In addition, its vapor pressure cannot be ignored. Vapor pressure reflects the ability of a substance to volatilize to the gas phase at a certain temperature. The vapor pressure of 1-nitro-2-chloro-5-fluorobenzene depends on its gas concentration in a confined space, which has a profound impact on safe production and use.
The above physical properties are interrelated, and need to be carefully considered in the research, production and application of 1-nitro-2-chloro-5-fluorobenzene to achieve the best effect.
First of all, its appearance, 1-nitro-2-chloro-5-fluorobenzene is usually a colorless to light yellow liquid, or a crystalline solid, depending on the temperature and environment. This appearance characteristic can be used as an important basis for preliminary identification and determination of its purity.
The melting point of this substance is about a specific range. The melting point is the critical temperature at which the substance changes from solid to liquid state. The melting point of 1-nitro-2-chloro-5-fluorobenzene has a great influence on its separation, purification and storage operations. If the temperature is higher than the melting point, it is in a liquid state; if it is lower than the melting point, it is in a solid state. Mastering the melting point helps to precisely control its physical state to meet different needs.
Besides the boiling point, the boiling point is the temperature at which a liquid turns into a gas. The boiling point of 1-nitro-2-chloro-5-fluorobenzene also has a specific value. The boiling point is closely related to the intermolecular forces. By understanding the boiling point, it can be effectively separated from other substances in separation procedures such as distillation to ensure its purity.
Solubility is also a key property. 1-nitro-2-chloro-5-fluorobenzene has a certain solubility in organic solvents, such as certain aromatics, halogenated hydrocarbons, etc., but has little solubility in water. This difference in solubility can be used to selectively separate and extract the substance during chemical synthesis, extraction, etc.
In terms of density, 1-nitro-2-chloro-5-fluorobenzene has a specific density value. Density can be used to measure the mass of a substance per unit volume, and is an important consideration when storing, transporting, and measuring related chemical reactions.
In addition, its vapor pressure cannot be ignored. Vapor pressure reflects the ability of a substance to volatilize to the gas phase at a certain temperature. The vapor pressure of 1-nitro-2-chloro-5-fluorobenzene depends on its gas concentration in a confined space, which has a profound impact on safe production and use.
The above physical properties are interrelated, and need to be carefully considered in the research, production and application of 1-nitro-2-chloro-5-fluorobenzene to achieve the best effect.
What is the chemical synthesis method of 1 - nitro - 2 - chloro - 5 - fluorobenzene
The chemical synthesis of 1-nitro-2-chloro-5-fluorobenzene is a key issue in the field of organic synthesis. The synthesis method needs to follow the principles of organic chemistry and many reaction paths.
One of the common methods is to use benzene as the initial raw material. The benzene is first nitrified, and the mixed acid of sulfuric acid and nitric acid is used as the nitrifying reagent. Under suitable temperature and conditions, a nitro group is introduced into the benzene ring to generate nitrobenzene. This reaction mechanism is electrophilic substitution, and nitro positive ions attack the benzene ring as electrophilic reagents.
After obtaining nitrobenzene, the halogenation reaction is carried out. Chlorine gas and a suitable catalyst, such as ferric chloride, under specific conditions, nitrobenzene is chlorinated, and chlorine atoms are introduced at specific positions in the benzene ring to generate 2-chloro-1-nitrobenzene. This halogenation reaction is also electrophilic substitution, and chlorine cations attack the benzene ring.
Then, the fluorination reaction is carried out. Often fluorinated reagents, such as potassium fluoride, are used to replace the chlorine atoms in 2-chloro-1-nitrobenzene with fluorine atoms under specific solvents and reaction conditions, resulting in 1-nitro-2-chloro-5-fluorobenzene. This is a nucleophilic substitution reaction, in which fluorine anions act as nucleophiles to attack the carbon atoms attached to chlorine on the benzene ring.
In addition, there may be other synthesis paths, which can be synthesized from different starting materials and through different reaction steps. The purpose of synthesizing 1-nitro-2-chloro-5-fluorobenzene is achieved. However, the above-mentioned synthesis route using benzene as the starting material is a more common and classic method, and it is often used in the practice of organic synthesis. During the synthesis process, the control of reaction conditions at each step, such as temperature, reaction time, and reagent dosage, are all crucial, which are related to the yield and purity of the product.
One of the common methods is to use benzene as the initial raw material. The benzene is first nitrified, and the mixed acid of sulfuric acid and nitric acid is used as the nitrifying reagent. Under suitable temperature and conditions, a nitro group is introduced into the benzene ring to generate nitrobenzene. This reaction mechanism is electrophilic substitution, and nitro positive ions attack the benzene ring as electrophilic reagents.
After obtaining nitrobenzene, the halogenation reaction is carried out. Chlorine gas and a suitable catalyst, such as ferric chloride, under specific conditions, nitrobenzene is chlorinated, and chlorine atoms are introduced at specific positions in the benzene ring to generate 2-chloro-1-nitrobenzene. This halogenation reaction is also electrophilic substitution, and chlorine cations attack the benzene ring.
Then, the fluorination reaction is carried out. Often fluorinated reagents, such as potassium fluoride, are used to replace the chlorine atoms in 2-chloro-1-nitrobenzene with fluorine atoms under specific solvents and reaction conditions, resulting in 1-nitro-2-chloro-5-fluorobenzene. This is a nucleophilic substitution reaction, in which fluorine anions act as nucleophiles to attack the carbon atoms attached to chlorine on the benzene ring.
In addition, there may be other synthesis paths, which can be synthesized from different starting materials and through different reaction steps. The purpose of synthesizing 1-nitro-2-chloro-5-fluorobenzene is achieved. However, the above-mentioned synthesis route using benzene as the starting material is a more common and classic method, and it is often used in the practice of organic synthesis. During the synthesis process, the control of reaction conditions at each step, such as temperature, reaction time, and reagent dosage, are all crucial, which are related to the yield and purity of the product.
1 - nitro - 2 - chloro - 5 - fluorobenzene in storage and transport
1 + -Nitro-2-chloro-5-fluorobenzene is an organic compound, and many matters must be paid attention to during storage and transportation.
One is related to storage. This compound should be placed in a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature and humid environment are prone to deterioration or dangerous chemical reactions. Therefore, the warehouse temperature should be controlled within an appropriate range and should be kept dry to prevent it from interacting with water vapor. At the same time, it needs to be stored separately from oxidants, reducing agents, bases, etc., and must not be mixed. This is because 1 + -nitro-2-chloro-5-fluorobenzene comes into contact with the above substances, or reacts violently, endangering safety.
Second, for transportation. When transporting, the packaging must be tight. Suitable packaging materials need to be selected to ensure that it is not damaged or leaked during transportation. Transportation vehicles should also have corresponding safety facilities, such as fire protection, explosion-proof devices, etc. Because of its flammability, explosive and other latent risks. And vibration, impact and friction should be avoided during transportation to prevent damage to the packaging and leakage of materials. Furthermore, transportation personnel should be professionally trained to be familiar with the characteristics and emergency treatment methods of 1 + -nitro-2-chloro-5-fluorobenzene, and can respond quickly and appropriately in case of emergencies.
In short, 1 + -nitro-2-chloro-5-fluorobenzene must strictly abide by relevant safety regulations during storage and transportation, from environmental control, item isolation, packaging protection to personnel training, etc., so as to ensure the safety of storage and transportation.
One is related to storage. This compound should be placed in a cool, dry and well-ventilated place. Because of its certain chemical activity, high temperature and humid environment are prone to deterioration or dangerous chemical reactions. Therefore, the warehouse temperature should be controlled within an appropriate range and should be kept dry to prevent it from interacting with water vapor. At the same time, it needs to be stored separately from oxidants, reducing agents, bases, etc., and must not be mixed. This is because 1 + -nitro-2-chloro-5-fluorobenzene comes into contact with the above substances, or reacts violently, endangering safety.
Second, for transportation. When transporting, the packaging must be tight. Suitable packaging materials need to be selected to ensure that it is not damaged or leaked during transportation. Transportation vehicles should also have corresponding safety facilities, such as fire protection, explosion-proof devices, etc. Because of its flammability, explosive and other latent risks. And vibration, impact and friction should be avoided during transportation to prevent damage to the packaging and leakage of materials. Furthermore, transportation personnel should be professionally trained to be familiar with the characteristics and emergency treatment methods of 1 + -nitro-2-chloro-5-fluorobenzene, and can respond quickly and appropriately in case of emergencies.
In short, 1 + -nitro-2-chloro-5-fluorobenzene must strictly abide by relevant safety regulations during storage and transportation, from environmental control, item isolation, packaging protection to personnel training, etc., so as to ensure the safety of storage and transportation.
Effects of 1 - nitro - 2 - chloro - 5 - fluorobenzene on the environment and human health
1-Nitro-2-chloro-5-fluorobenzene, its impact on the environment and human health is really crucial.
At the environmental end, once this substance is released into nature, it will cause great harm. If it flows into the water body, it may cause malignant water quality changes, affecting the habitat and reproduction of aquatic organisms. Microorganisms in the water may cause metabolic disorders, and algae growth will be disturbed, destroying the water ecological balance. Inflow into the soil can cause soil pollution, reduce soil fertility, affect the absorption of nutrients by plant roots, and hinder the normal growth of plants. And because it has a certain stability, it is difficult to degrade, or it remains in the environment for a long time, accumulating and causing more serious harm.
As for human health, its impact should not be underestimated. It may enter the human body through breathing, skin contact or accidental ingestion, which may cause many health problems. Or irritate the respiratory tract, cause symptoms such as cough and asthma, and long-term exposure or damage lung function. Contact with skin, or cause adverse reactions such as allergies, redness, swelling, and itching. If ingested by mistake, it may damage the digestive system, causing nausea, vomiting, abdominal pain, etc. In particular, studies suggest that it may be potentially carcinogenic, and long-term exposure may increase the risk of cancer.
In summary, 1-nitro-2-chloro-5-fluorobenzene has potential threats to the environment and human health. It should be treated with caution to prevent its wanton spread to ensure ecological safety and personal health.
At the environmental end, once this substance is released into nature, it will cause great harm. If it flows into the water body, it may cause malignant water quality changes, affecting the habitat and reproduction of aquatic organisms. Microorganisms in the water may cause metabolic disorders, and algae growth will be disturbed, destroying the water ecological balance. Inflow into the soil can cause soil pollution, reduce soil fertility, affect the absorption of nutrients by plant roots, and hinder the normal growth of plants. And because it has a certain stability, it is difficult to degrade, or it remains in the environment for a long time, accumulating and causing more serious harm.
As for human health, its impact should not be underestimated. It may enter the human body through breathing, skin contact or accidental ingestion, which may cause many health problems. Or irritate the respiratory tract, cause symptoms such as cough and asthma, and long-term exposure or damage lung function. Contact with skin, or cause adverse reactions such as allergies, redness, swelling, and itching. If ingested by mistake, it may damage the digestive system, causing nausea, vomiting, abdominal pain, etc. In particular, studies suggest that it may be potentially carcinogenic, and long-term exposure may increase the risk of cancer.
In summary, 1-nitro-2-chloro-5-fluorobenzene has potential threats to the environment and human health. It should be treated with caution to prevent its wanton spread to ensure ecological safety and personal health.
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