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1-(Trifluoromethyl)-4-Chlorobenzene
Linshang Chemical
|
HS Code |
116769 |
| Chemical Formula | C7H4ClF3 |
| Molar Mass | 180.55 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | 162 - 164 °C |
| Density | 1.339 g/mL at 25 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | 52 °C |
| Refractive Index | 1.4565 at 20 °C |
As an accredited 1-(Trifluoromethyl)-4-Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 1-(trifluoromethyl)-4-chlorobenzene packaged in a sealed glass bottle. |
| Storage | 1-(Trifluoromethyl)-4-chlorobenzene should be stored in a cool, well - ventilated area, away from heat sources and open flames. Keep it in a tightly closed container to prevent vapor leakage. Store it separately from oxidizing agents, reducing agents, and reactive chemicals to avoid potential reactions. Ensure the storage location has appropriate spill - containment measures. |
| Shipping | 1-(Trifluoromethyl)-4-chlorobenzene is shipped in well - sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations, ensuring proper labeling, handling, and transportation to prevent spills and environmental risks. |
Competitive 1-(Trifluoromethyl)-4-Chlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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What are the main uses of 1- (trifluoromethyl) -4-chlorobenzene?
The main application of (triethylmethyl) -4-bromobenzene is its important performance in the field of polymorphism.
In the field of synthesis, it is also important. Due to the specialization of (triethylmethyl) -4-bromobenzene, it can be used to generate a wide range of polymorphism, so as to improve the molecular framework of the material. For example, the cross-coupling of the aryl group can be combined with specific gold compounds, and the synthesis of materials with specific biological activities is essential for the research of anti-disease substances.
In the field of materials science, it also has an extraordinary appearance. It can be used as a starting material for the synthesis of functional polymer materials. For example, with its polymerization reaction, it is possible to obtain polymers with special optical and optical properties. This polymer can be used in optical devices such as optical diodes (OLEDs) and solar energy pools to improve their performance, such as increasing the optical efficiency of the device, extending the service life, etc.
Furthermore, in the research room of chemical research, (triethylmethyl) - 4-bromobenzene is often a common substrate for research on synthesis methods. By exploring its various reactions, such as nuclear substitution, nuclear substitution, and other reactions, we can explore new synthesis methods, improve the efficiency of synthesis, and promote the development of chemical technology.
Therefore, the chemical properties of (triethylmethyl) -4-bromobenzene have indispensable uses in many aspects, such as research on materials, materials, and chemicals.
In the field of synthesis, it is also important. Due to the specialization of (triethylmethyl) -4-bromobenzene, it can be used to generate a wide range of polymorphism, so as to improve the molecular framework of the material. For example, the cross-coupling of the aryl group can be combined with specific gold compounds, and the synthesis of materials with specific biological activities is essential for the research of anti-disease substances.
In the field of materials science, it also has an extraordinary appearance. It can be used as a starting material for the synthesis of functional polymer materials. For example, with its polymerization reaction, it is possible to obtain polymers with special optical and optical properties. This polymer can be used in optical devices such as optical diodes (OLEDs) and solar energy pools to improve their performance, such as increasing the optical efficiency of the device, extending the service life, etc.
Furthermore, in the research room of chemical research, (triethylmethyl) - 4-bromobenzene is often a common substrate for research on synthesis methods. By exploring its various reactions, such as nuclear substitution, nuclear substitution, and other reactions, we can explore new synthesis methods, improve the efficiency of synthesis, and promote the development of chemical technology.
Therefore, the chemical properties of (triethylmethyl) -4-bromobenzene have indispensable uses in many aspects, such as research on materials, materials, and chemicals.
What are the physical properties of 1- (trifluoromethyl) -4-chlorobenzene?
The physical properties of triethyl-4-bromonaphthalene are as follows:
Looking at it, it is mostly solid at room temperature. The color may be white to light yellow, which varies depending on its purity and impurities.
Smell it, or it has a special smell, but its taste is not strong and pungent, but milder and can be detected in specific environments.
In terms of its melting point, it is about [X] degrees Celsius. This temperature causes the substance to gradually melt from solid to liquid. The exact value of the melting point will vary slightly depending on the measurement method and the purity of the sample.
As for the boiling point, it is about [X] degrees Celsius. When the temperature reaches this point, the substance will be converted from liquid to gaseous and escape.
In terms of solubility, triethyl-4-bromonaphthalene exhibits good solubility in organic solvents, such as ethanol, ether, chloroform, etc., and can be miscible with it to form a uniform solution. However, in water, its solubility is very small. Due to the characteristics of its molecular structure, it is difficult to form an effective interaction with water molecules, so it is not easily soluble in water.
The density is higher than that of water. If it is mixed with water, it can be seen to sink to the bottom after standing. This density characteristic is also related to the composition and accumulation of molecules.
In addition, the stability of the substance is acceptable under normal conditions, but in case of strong oxidizing agents, strong acids, strong bases and other chemical substances, or extreme environments such as high temperatures and open flames, chemical reactions may occur, causing changes in its physical and chemical properties.
Looking at it, it is mostly solid at room temperature. The color may be white to light yellow, which varies depending on its purity and impurities.
Smell it, or it has a special smell, but its taste is not strong and pungent, but milder and can be detected in specific environments.
In terms of its melting point, it is about [X] degrees Celsius. This temperature causes the substance to gradually melt from solid to liquid. The exact value of the melting point will vary slightly depending on the measurement method and the purity of the sample.
As for the boiling point, it is about [X] degrees Celsius. When the temperature reaches this point, the substance will be converted from liquid to gaseous and escape.
In terms of solubility, triethyl-4-bromonaphthalene exhibits good solubility in organic solvents, such as ethanol, ether, chloroform, etc., and can be miscible with it to form a uniform solution. However, in water, its solubility is very small. Due to the characteristics of its molecular structure, it is difficult to form an effective interaction with water molecules, so it is not easily soluble in water.
The density is higher than that of water. If it is mixed with water, it can be seen to sink to the bottom after standing. This density characteristic is also related to the composition and accumulation of molecules.
In addition, the stability of the substance is acceptable under normal conditions, but in case of strong oxidizing agents, strong acids, strong bases and other chemical substances, or extreme environments such as high temperatures and open flames, chemical reactions may occur, causing changes in its physical and chemical properties.
What are the chemical properties of 1- (trifluoromethyl) -4-chlorobenzene?
Triethyl-4-bromoaniline, this is an organic compound. Its chemical properties are unique and valuable for investigation.
Structurally, triethyl occupies a specific position, which endows the compound with a certain steric hindrance and electronic effect. Ethyl group, as a power supply group, can affect the electron cloud density of the benzene ring, making the electron cloud density of the benzene ring o-para relatively increased, and it is more prone to electrophilic substitution reactions.
The presence of bromine atoms is also key. Although bromine atoms have electron-absorbing induction effects, they have electron-giving conjugation effects. Under the synthesis, the effect on the reactivity of the benzene ring is complex. In many reactions, bromine atoms can be used as leaving groups to participate in nucleophilic substitution reactions, such as reacting with nucleophilic reagents, bromine atoms leave, and nucleophilic reagents replace them to achieve functional group transformation.
In common organic reactions, triethyl-4-bromoaniline can participate in arylation reactions. Under suitable catalysts and reaction conditions, it can be coupled with other aryl halides or olefins to form carbon-carbon bonds and synthesize organic molecules with more complex structures, which are widely used in drug synthesis, materials science and other fields. At the same time, due to the presence of amino groups, acylation, alkylation and other reactions can occur, which can further modify the compound and expand its application in different fields. In conclusion, triethyl-4-bromoaniline has rich chemical properties and is of great significance in the field of organic synthetic chemistry.
Structurally, triethyl occupies a specific position, which endows the compound with a certain steric hindrance and electronic effect. Ethyl group, as a power supply group, can affect the electron cloud density of the benzene ring, making the electron cloud density of the benzene ring o-para relatively increased, and it is more prone to electrophilic substitution reactions.
The presence of bromine atoms is also key. Although bromine atoms have electron-absorbing induction effects, they have electron-giving conjugation effects. Under the synthesis, the effect on the reactivity of the benzene ring is complex. In many reactions, bromine atoms can be used as leaving groups to participate in nucleophilic substitution reactions, such as reacting with nucleophilic reagents, bromine atoms leave, and nucleophilic reagents replace them to achieve functional group transformation.
In common organic reactions, triethyl-4-bromoaniline can participate in arylation reactions. Under suitable catalysts and reaction conditions, it can be coupled with other aryl halides or olefins to form carbon-carbon bonds and synthesize organic molecules with more complex structures, which are widely used in drug synthesis, materials science and other fields. At the same time, due to the presence of amino groups, acylation, alkylation and other reactions can occur, which can further modify the compound and expand its application in different fields. In conclusion, triethyl-4-bromoaniline has rich chemical properties and is of great significance in the field of organic synthetic chemistry.
What are the preparation methods of 1- (trifluoromethyl) -4-chlorobenzene?
To prepare the medicine of 1- (triethyl) -4-bromonaphthalene, there are the following methods:
First, the naphthalene is used as the beginning, and 4-bromonaphthalene can be obtained by the method of bromination. After the 4-bromonaphthalene is encountered with the triethylmethylation reagent, with the help of appropriate temperature and catalyst, the two are phased to obtain 1- (triethylmethyl) -4-bromonaphthalene. In this step, bromine and appropriate catalysts, such as iron powder, can be used to guide bromonaphthalene on the ring of naphthalene to obtain 4-bromonaphthalene. At the time of triethylation, the selected reagents and reaction conditions are essential, which are related to the yield and purity of the product.
Second, the raw material containing triethylmethyl is first taken and interacted with the naphthalene series compound. Under special conditions, the naphthalene and a triethylmethylation precursor can be reacted with electrophilic substitution to introduce triethylmethyl first. Then, the bromination step is carried out. This sequence requires detailed control of the reaction check point and conditions, so that the bromine is exactly in the 4 position. The activity of the capping naphthalene ring and the localization effect of the substituent can lead to a specific position of bromine during bromination to obtain the target product.
Third, there are also methods for structural rearrangement or group conversion based on compounds containing bromine and triethyl methyl. Such reactions may involve complex mechanisms and special reagents, such as rearrangement reactions catalyzed by some metals. After exquisite design, the groups in the molecule migrate and transform to form 1- (triethylmethyl) -4-bromonaphthalene. However, such methods have high requirements for reaction operation and condition control, and require fine operation to achieve the desired result.
All production methods have advantages and disadvantages. In actual production, when the availability of raw materials, cost, yield and purity are required, the appropriate method should be selected.
First, the naphthalene is used as the beginning, and 4-bromonaphthalene can be obtained by the method of bromination. After the 4-bromonaphthalene is encountered with the triethylmethylation reagent, with the help of appropriate temperature and catalyst, the two are phased to obtain 1- (triethylmethyl) -4-bromonaphthalene. In this step, bromine and appropriate catalysts, such as iron powder, can be used to guide bromonaphthalene on the ring of naphthalene to obtain 4-bromonaphthalene. At the time of triethylation, the selected reagents and reaction conditions are essential, which are related to the yield and purity of the product.
Second, the raw material containing triethylmethyl is first taken and interacted with the naphthalene series compound. Under special conditions, the naphthalene and a triethylmethylation precursor can be reacted with electrophilic substitution to introduce triethylmethyl first. Then, the bromination step is carried out. This sequence requires detailed control of the reaction check point and conditions, so that the bromine is exactly in the 4 position. The activity of the capping naphthalene ring and the localization effect of the substituent can lead to a specific position of bromine during bromination to obtain the target product.
Third, there are also methods for structural rearrangement or group conversion based on compounds containing bromine and triethyl methyl. Such reactions may involve complex mechanisms and special reagents, such as rearrangement reactions catalyzed by some metals. After exquisite design, the groups in the molecule migrate and transform to form 1- (triethylmethyl) -4-bromonaphthalene. However, such methods have high requirements for reaction operation and condition control, and require fine operation to achieve the desired result.
All production methods have advantages and disadvantages. In actual production, when the availability of raw materials, cost, yield and purity are required, the appropriate method should be selected.
What are the precautions for storing and transporting 1- (trifluoromethyl) -4-chlorobenzene?
"Tiangong Kaiwu" says: "All matters related to the storage and transportation of triethyl and tetrabromonaphthalene should not be careless."
Triethyl substances are very lively, and when stored, the first thing to pay attention to is the density of their objects. If the vessel is not dense, it is easy to contact with other objects and melt, or escape from the outside, causing gas to be miscellaneous, and there is a risk of explosion. Therefore, it must be filled with strong and dense utensils, placed in a cool and dry place, far from heat sources and open flames.
Tetrabromonaphthalene is toxic and corrosive. The storage container should be resistant to its rot, and suitable materials should be selected, such as special glass utensils or corrosion-resistant plastic utensils. The storage place must be well connected to avoid the accumulation of its gas, in order to prevent harm to people and animals. When handling, it should be light and stable to prevent the damage of the device from causing it to leak.
When transporting, the triethyl should be driven slowly to avoid the leakage of its shock-inducing device. And the car should be equipped with fire extinguishing equipment, just in case. The transportation of tetrabromonaphthalene must comply with strict regulations, and the carrier must be marked with its risk. The escort should be familiar with its nature and know the emergency method. If there is a situation on the way, it can be dealt with quickly to avoid the delay of disaster.
In general, triethyl and tetrabromonaphthalene are both safety-related in storage and transportation, and must be carefully investigated, followed by regulations, and important to ensure that everything goes smoothly and is safe.
Triethyl substances are very lively, and when stored, the first thing to pay attention to is the density of their objects. If the vessel is not dense, it is easy to contact with other objects and melt, or escape from the outside, causing gas to be miscellaneous, and there is a risk of explosion. Therefore, it must be filled with strong and dense utensils, placed in a cool and dry place, far from heat sources and open flames.
Tetrabromonaphthalene is toxic and corrosive. The storage container should be resistant to its rot, and suitable materials should be selected, such as special glass utensils or corrosion-resistant plastic utensils. The storage place must be well connected to avoid the accumulation of its gas, in order to prevent harm to people and animals. When handling, it should be light and stable to prevent the damage of the device from causing it to leak.
When transporting, the triethyl should be driven slowly to avoid the leakage of its shock-inducing device. And the car should be equipped with fire extinguishing equipment, just in case. The transportation of tetrabromonaphthalene must comply with strict regulations, and the carrier must be marked with its risk. The escort should be familiar with its nature and know the emergency method. If there is a situation on the way, it can be dealt with quickly to avoid the delay of disaster.
In general, triethyl and tetrabromonaphthalene are both safety-related in storage and transportation, and must be carefully investigated, followed by regulations, and important to ensure that everything goes smoothly and is safe.
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