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2-(2-Chloroethoxy)Benzene Sulfonamide
Linshang Chemical
|
HS Code |
753477 |
| Chemical Formula | C8H10ClNO3S |
| Molar Mass | 235.69 g/mol |
| Appearance | Solid (usually) |
| Physical State At Room Temperature | Solid |
| Solubility In Water | Low solubility |
| Melting Point | Data - specific value needed |
| Boiling Point | Data - specific value needed |
| Density | Data - specific value needed |
| Vapor Pressure | Low vapor pressure |
| Stability | Stable under normal conditions |
As an accredited 2-(2-Chloroethoxy)Benzene Sulfonamide factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 2-(2 - chloroethoxy)benzene Sulfonamide in sealed, labeled chemical - grade bags. |
| Storage | Store 2-(2 - chloroethoxy)benzenesulfonamide in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances like strong oxidizers and bases. Store in a tightly - sealed container to prevent moisture absorption and potential degradation, ensuring its stability and safety during storage. |
| Shipping | 2-(2 - chloroethoxy)benzene Sulfonamide is shipped in accordance with strict chemical regulations. Packed in corrosion - resistant containers, it's transported by approved carriers, ensuring safe handling to prevent any leakage or damage during transit. |
Competitive 2-(2-Chloroethoxy)Benzene Sulfonamide prices that fit your budget—flexible terms and customized quotes for every order.
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As a leading 2-(2-Chloroethoxy)Benzene Sulfonamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 2- (2 - chloroethoxy) benzene Sulfonamide?
2-%282+-+chloroethoxy%29benzene Sulfonamide, this is the name of an organic compound. In ancient Chinese, its chemical structure is explored as follows:
"2- (2-chloroethoxy) benzenesulfonamide", which contains key structural elements. First look at "benzenesulfonamide", which is based on the benzene ring. On the benzene ring, a sulfonyl group (-SO2O -) is connected to an amino group (-NH2O) to form the basic structure of benzenesulfonamide, which is the core and main part of the compound.
Then look at "2- (2-chloroethoxy) ", which is the substituent on the benzene ring. " "2-Chloroethoxy" means that there is an ethoxy group (-O-CH ² -CH 😉), and the second position of the ethoxy group (that is, the ortho-position of the carbon atom connected to the oxygen) is replaced by the chlorine atom (Cl). This substituent is connected to the second position of the benzene ring.
In summary, the chemical structure of 2 - (2-chloroethoxy) benzenesulfonamide is based on benzene sulfonamide as the main body, and the 2-chloroethoxy group is connected to the second position of the benzene ring, so that the unique chemical structure of this organic compound is constructed.
"2- (2-chloroethoxy) benzenesulfonamide", which contains key structural elements. First look at "benzenesulfonamide", which is based on the benzene ring. On the benzene ring, a sulfonyl group (-SO2O -) is connected to an amino group (-NH2O) to form the basic structure of benzenesulfonamide, which is the core and main part of the compound.
Then look at "2- (2-chloroethoxy) ", which is the substituent on the benzene ring. " "2-Chloroethoxy" means that there is an ethoxy group (-O-CH ² -CH 😉), and the second position of the ethoxy group (that is, the ortho-position of the carbon atom connected to the oxygen) is replaced by the chlorine atom (Cl). This substituent is connected to the second position of the benzene ring.
In summary, the chemical structure of 2 - (2-chloroethoxy) benzenesulfonamide is based on benzene sulfonamide as the main body, and the 2-chloroethoxy group is connected to the second position of the benzene ring, so that the unique chemical structure of this organic compound is constructed.
What are the physical properties of 2- (2 - chloroethoxy) benzene Sulfonamide?
2-%282+-+chloroethoxy%29benzene Sulfonamide is 2 - (2 - chloroethoxy) benzenesulfonamide. The physical properties of this substance are described as follows:
1. ** Appearance properties **: At room temperature, 2 - (2 - chloroethoxy) benzenesulfonamide is often white to off-white crystalline powder. This appearance characteristic, like fine jade chips, has uniform texture and pure color. Viewed under light, it is slightly shiny, reflecting the regular and orderly internal structure.
2. ** Melting boiling point **: Its melting point is in a specific temperature range, usually between 130 - 135 ° C. When the temperature gradually rises to the melting point, this substance slowly melts from solid to liquid, just like ice and snow melt when warm. As for the boiling point, under normal pressure conditions, a higher temperature is required to make it boil and vaporize, but the exact boiling point value varies slightly due to different accurate measurement conditions.
3. ** Solubility **: 2 - (2 - chloroethoxy) benzenesulfonamide exhibits different solubility properties in different solvents. In water, its solubility is low, slightly soluble in water, just like oil floats in water, and it is difficult to dissolve. Due to the large difference between the polarity of the molecular structure of the substance and the polarity of the water molecule. In organic solvents, such as ethanol and acetone, its solubility is relatively high, and it can be better dissolved to form a uniform solution. This is due to the existence of suitable interaction forces between organic solvents and the molecules of the substance.
4. ** Density and stability **: Its density is similar to that of common organic compounds. In the solid state, the structure is relatively stable. In the normal environment, it can be stored for a long time without significant chemical changes. However, if it is under extreme conditions such as high temperature, strong acid, and strong base, its stability will be affected, and the molecular structure may change, triggering chemical reactions.
5. ** Odor and volatility **: 2 - (2 - chloroethoxy) benzenesulfonamide has a weak odor. If it is not carefully sniffed at close range, it is almost invisible. And its volatility is low, at room temperature and pressure, only a very small amount of molecules evaporate from the solid surface into the air, which makes it less susceptible to loss due to volatilization during general storage and use.
1. ** Appearance properties **: At room temperature, 2 - (2 - chloroethoxy) benzenesulfonamide is often white to off-white crystalline powder. This appearance characteristic, like fine jade chips, has uniform texture and pure color. Viewed under light, it is slightly shiny, reflecting the regular and orderly internal structure.
2. ** Melting boiling point **: Its melting point is in a specific temperature range, usually between 130 - 135 ° C. When the temperature gradually rises to the melting point, this substance slowly melts from solid to liquid, just like ice and snow melt when warm. As for the boiling point, under normal pressure conditions, a higher temperature is required to make it boil and vaporize, but the exact boiling point value varies slightly due to different accurate measurement conditions.
3. ** Solubility **: 2 - (2 - chloroethoxy) benzenesulfonamide exhibits different solubility properties in different solvents. In water, its solubility is low, slightly soluble in water, just like oil floats in water, and it is difficult to dissolve. Due to the large difference between the polarity of the molecular structure of the substance and the polarity of the water molecule. In organic solvents, such as ethanol and acetone, its solubility is relatively high, and it can be better dissolved to form a uniform solution. This is due to the existence of suitable interaction forces between organic solvents and the molecules of the substance.
4. ** Density and stability **: Its density is similar to that of common organic compounds. In the solid state, the structure is relatively stable. In the normal environment, it can be stored for a long time without significant chemical changes. However, if it is under extreme conditions such as high temperature, strong acid, and strong base, its stability will be affected, and the molecular structure may change, triggering chemical reactions.
5. ** Odor and volatility **: 2 - (2 - chloroethoxy) benzenesulfonamide has a weak odor. If it is not carefully sniffed at close range, it is almost invisible. And its volatility is low, at room temperature and pressure, only a very small amount of molecules evaporate from the solid surface into the air, which makes it less susceptible to loss due to volatilization during general storage and use.
What are the common uses of 2- (2 - chloroethoxy) benzene Sulfonamide?
2-%282+-+chloroethoxy%29benzene+Sulfonamide is 2 - (2 - chloroethoxy) benzenesulfonamide, which is an organic compound and has a wide range of uses in the fields of medicine and chemical industry. Its common uses are as follows:
First, in the field of pharmaceutical research and development, it is often used as a key intermediate. Because the structure contains sulfonamide groups, it has a variety of biological activities. For example, some drugs made from this intermediate can act on specific enzymes or receptors, and have a regulatory effect on inflammatory reactions, which is of great significance in the development of anti-inflammatory drugs; some can interfere with cell metabolism or be used in the creation of anti-tumor drugs.
Second, in the field of chemical synthesis, it can participate in a variety of organic reactions to achieve the construction of complex organic molecules. By reacting with different reagents, unique functional groups can be introduced to change the physical and chemical properties of the products, such as improving the stability and solubility of compounds, and playing an important role in the synthesis of fine chemical products such as special surfactants and high-performance material additives.
Third, in the research and development of agricultural chemicals, 2 - (2 - chloroethoxy) benzenesulfonamide also has potential applications. Or it can be developed as a new type of pesticide, which inhibits the growth and reproduction of pests through its biological activity, is beneficial to the control of crop diseases and pests, and is expected to have higher selectivity and environmental friendliness than traditional pesticides.
First, in the field of pharmaceutical research and development, it is often used as a key intermediate. Because the structure contains sulfonamide groups, it has a variety of biological activities. For example, some drugs made from this intermediate can act on specific enzymes or receptors, and have a regulatory effect on inflammatory reactions, which is of great significance in the development of anti-inflammatory drugs; some can interfere with cell metabolism or be used in the creation of anti-tumor drugs.
Second, in the field of chemical synthesis, it can participate in a variety of organic reactions to achieve the construction of complex organic molecules. By reacting with different reagents, unique functional groups can be introduced to change the physical and chemical properties of the products, such as improving the stability and solubility of compounds, and playing an important role in the synthesis of fine chemical products such as special surfactants and high-performance material additives.
Third, in the research and development of agricultural chemicals, 2 - (2 - chloroethoxy) benzenesulfonamide also has potential applications. Or it can be developed as a new type of pesticide, which inhibits the growth and reproduction of pests through its biological activity, is beneficial to the control of crop diseases and pests, and is expected to have higher selectivity and environmental friendliness than traditional pesticides.
What are the synthesis methods of 2- (2 - chloroethoxy) benzene Sulfonamide?
To prepare 2 - (2 - chloroethoxy) benzenesulfonamide, there are various methods. The first common method is to use 2 - hydroxybenzenesulfonamide and 2 - chloroethanol as raw materials, under the catalysis of alkali, through nucleophilic substitution reaction. Among them, the base can be selected from potassium carbonate, sodium hydroxide or the like, and in a suitable solvent, such as N, N - dimethylformamide (DMF), dimethyl sulfoxide (DMSO), the reaction is stirred at a controlled temperature. The temperature is controlled, about 50 - 100 ℃, depending on the activity of the raw material and the reaction process. After the reaction is completed, the pure product is obtained by conventional separation and purification methods, such as extraction, column chromatography, etc.
Another method can first react phenol with 2-chloroethanol to obtain 2- (2-chloroethoxy) phenol, and then sulfonate with sulfonating reagents, such as fuming sulfuric acid, chlorosulfonic acid, etc., and then react with ammonia or amine to convert into sulfonamide. When sulfonating, pay attention to the reaction conditions, such as temperature and the ratio of reagent dosage, to prevent side reactions such as polysulfonation. After the reaction is completed, the target product is obtained through a series of purification steps.
Furthermore, starting from benzene, it can be chloroethylated to obtain 2- (2-chloroethoxy) benzene, and then prepared in the order of sulfonation and amidation. This route is a bit complicated, but the raw materials are easy to obtain, and it is also of practical value. Each method has its own advantages and disadvantages, and it is necessary to choose the best one according to the actual situation, such as the cost and availability of raw materials, the purity requirements of the product, etc., and carefully adjust the reaction to obtain high yield and high purity 2 - (2-chloroethoxy) benzenesulfonamide.
Another method can first react phenol with 2-chloroethanol to obtain 2- (2-chloroethoxy) phenol, and then sulfonate with sulfonating reagents, such as fuming sulfuric acid, chlorosulfonic acid, etc., and then react with ammonia or amine to convert into sulfonamide. When sulfonating, pay attention to the reaction conditions, such as temperature and the ratio of reagent dosage, to prevent side reactions such as polysulfonation. After the reaction is completed, the target product is obtained through a series of purification steps.
Furthermore, starting from benzene, it can be chloroethylated to obtain 2- (2-chloroethoxy) benzene, and then prepared in the order of sulfonation and amidation. This route is a bit complicated, but the raw materials are easy to obtain, and it is also of practical value. Each method has its own advantages and disadvantages, and it is necessary to choose the best one according to the actual situation, such as the cost and availability of raw materials, the purity requirements of the product, etc., and carefully adjust the reaction to obtain high yield and high purity 2 - (2-chloroethoxy) benzenesulfonamide.
What are the potential safety risks of 2- (2 - chloroethoxy) benzene Sulfonamide?
2-%282+-+chloroethoxy%29benzene Sulfonamide, Chinese name 2- (2-chloroethoxy) benzenesulfonamide, this compound has several potential safety risks and is related to human health and the environment.
First of all, it may be toxic to human health. If it enters the human body through inhalation, ingestion or skin contact, it may be harmful to health. Inhalation of its dust or vapor can easily irritate the respiratory tract, cause cough, asthma and other symptoms, and long-term exposure may even cause damage to lung function. After ingestion, it will irritate the gastrointestinal tract, causing nausea, vomiting, abdominal pain and other discomfort, and in severe cases affect the normal operation of the digestive system. Skin contact may cause skin allergies, itching, redness and swelling, etc. If the contact area is large and long-term, it may also be absorbed through the skin, which may have adverse effects on the whole body.
From an environmental point of view, it is difficult to degrade in the environment. If discharged into the natural environment, it will remain in soil and water bodies, causing damage to soil ecology and aquatic ecosystems. For example, it will affect the normal activities of soil microorganisms, change soil structure and fertility; in water bodies, it may be toxic to aquatic organisms, affect the survival and reproduction of fish, plankton, etc., destroy the aquatic biological chain, and then affect the balance of the entire ecosystem.
When handling 2- (2-chloroethoxy) benzenesulfonamide, safety operating procedures must be strictly followed. Operators should wear protective clothing, gloves, protective glasses and other protective equipment to avoid direct contact. The place of use should have good ventilation conditions to reduce the concentration of dust and vapor in the air. In the event of a leak, emergency measures should be taken immediately to properly collect and dispose of the leak to prevent the spread of pollution.
First of all, it may be toxic to human health. If it enters the human body through inhalation, ingestion or skin contact, it may be harmful to health. Inhalation of its dust or vapor can easily irritate the respiratory tract, cause cough, asthma and other symptoms, and long-term exposure may even cause damage to lung function. After ingestion, it will irritate the gastrointestinal tract, causing nausea, vomiting, abdominal pain and other discomfort, and in severe cases affect the normal operation of the digestive system. Skin contact may cause skin allergies, itching, redness and swelling, etc. If the contact area is large and long-term, it may also be absorbed through the skin, which may have adverse effects on the whole body.
From an environmental point of view, it is difficult to degrade in the environment. If discharged into the natural environment, it will remain in soil and water bodies, causing damage to soil ecology and aquatic ecosystems. For example, it will affect the normal activities of soil microorganisms, change soil structure and fertility; in water bodies, it may be toxic to aquatic organisms, affect the survival and reproduction of fish, plankton, etc., destroy the aquatic biological chain, and then affect the balance of the entire ecosystem.
When handling 2- (2-chloroethoxy) benzenesulfonamide, safety operating procedures must be strictly followed. Operators should wear protective clothing, gloves, protective glasses and other protective equipment to avoid direct contact. The place of use should have good ventilation conditions to reduce the concentration of dust and vapor in the air. In the event of a leak, emergency measures should be taken immediately to properly collect and dispose of the leak to prevent the spread of pollution.
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