Linshang Chemical
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2,3,4-Trichlorobenzenesulphonyl Chloride
Linshang Chemical
|
HS Code |
214257 |
| Chemical Formula | C6HCl5O2S |
| Molecular Weight | 305.39 g/mol |
| Appearance | Solid (usually a white - off - white powder) |
| Physical State At Room Temp | Solid |
| Odor | Pungent, characteristic |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like dichloromethane, chloroform |
| Melting Point | Around 110 - 115 °C |
| Boiling Point | Decomposes before boiling |
| Stability | Reactive, especially towards nucleophiles |
| Hazard Class | Corrosive, harmful if swallowed, in contact with skin or if inhaled |
As an accredited 2,3,4-Trichlorobenzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 1 kg of 2,3,4 - trichlorobenzenesulphonyl Chloride packaged in a sealed, corrosion - resistant container. |
| Storage | 2,3,4 - Trichlorobenzenesulphonyl Chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. Keep it in a tightly - sealed container to prevent moisture and air contact, as it may react with them. Store separately from incompatible substances like bases, reducing agents, and water - reactive materials to avoid potential hazardous reactions. |
| Shipping | 2,3,4 - Trichlorobenzenesulphonyl Chloride is a chemical that requires careful shipping. It should be packed in corrosion - resistant containers, stored away from heat and moisture, and transported following strict hazardous material regulations. |
Competitive 2,3,4-Trichlorobenzenesulphonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2,3,4-Trichlorobenzenesulphonyl Chloride in China?
As a trusted 2,3,4-Trichlorobenzenesulphonyl Chloride manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2,3,4-Trichlorobenzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2,3,4-trichlorobenzenesulfonyl chloride?
2% 2C3% 2C4-trifluorobenzoate ethyl ester is a crucial raw material in organic synthesis and has a wide range of uses in many fields. Its main uses are as follows:
First, in the field of pharmaceutical synthesis, this compound can be used as a key intermediate for the preparation of a variety of specific drugs. For example, some drugs with antibacterial and anti-inflammatory effects, 2% 2C3% 2C4-trifluorobenzoate participate in the synthesis of drug structures, which can more accurately act on pathogens or inflammatory sites, improve drug efficacy, and reduce damage to human normal cells. Or the synthesis of some anti-tumor drugs, whose special chemical structure can promote synthetic drugs to better interfere with the metabolism and proliferation of tumor cells, providing strong support for cancer treatment.
Second, in the synthesis of pesticides, 2% 2C3% 2C4-trifluorobenzoate ethyl ester also plays an indispensable role. By participating in the synthesis of new pesticides, it can significantly enhance the insecticidal and bactericidal properties of pesticides, and by virtue of its chemical stability, it can prolong the shelf life of pesticides to a certain extent. At the same time, compared with traditional pesticides, pesticides synthesized from this raw material have less impact on the environment, are more in line with the current green agricultural development concept, and help to achieve sustainable agricultural development.
Third, in the field of materials science, 2% 2C3% 2C4-trifluorobenzoate ethyl ester can be used to prepare polymer materials with excellent performance. After a specific chemical reaction, it is introduced into the polymer structure, which can impart materials such as excellent corrosion resistance, high temperature resistance, and good mechanical properties. For example, special materials used in the aerospace field, or component materials that require high stability and reliability in electronic equipment, 2% 2C3% 2C4-trifluorobenzoate can be used to optimize material properties to meet the needs of special environments.
First, in the field of pharmaceutical synthesis, this compound can be used as a key intermediate for the preparation of a variety of specific drugs. For example, some drugs with antibacterial and anti-inflammatory effects, 2% 2C3% 2C4-trifluorobenzoate participate in the synthesis of drug structures, which can more accurately act on pathogens or inflammatory sites, improve drug efficacy, and reduce damage to human normal cells. Or the synthesis of some anti-tumor drugs, whose special chemical structure can promote synthetic drugs to better interfere with the metabolism and proliferation of tumor cells, providing strong support for cancer treatment.
Second, in the synthesis of pesticides, 2% 2C3% 2C4-trifluorobenzoate ethyl ester also plays an indispensable role. By participating in the synthesis of new pesticides, it can significantly enhance the insecticidal and bactericidal properties of pesticides, and by virtue of its chemical stability, it can prolong the shelf life of pesticides to a certain extent. At the same time, compared with traditional pesticides, pesticides synthesized from this raw material have less impact on the environment, are more in line with the current green agricultural development concept, and help to achieve sustainable agricultural development.
Third, in the field of materials science, 2% 2C3% 2C4-trifluorobenzoate ethyl ester can be used to prepare polymer materials with excellent performance. After a specific chemical reaction, it is introduced into the polymer structure, which can impart materials such as excellent corrosion resistance, high temperature resistance, and good mechanical properties. For example, special materials used in the aerospace field, or component materials that require high stability and reliability in electronic equipment, 2% 2C3% 2C4-trifluorobenzoate can be used to optimize material properties to meet the needs of special environments.
What are the physical properties of 2,3,4-trichlorobenzenesulfonyl chloride?
2%2C3%2C4-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF, this is a unique chemical substance. Its physical properties are worthy of in-depth investigation.
First of all, its appearance, at room temperature, is mostly colorless and transparent, like clear water, pure and free of variegated colors, and it makes people feel clear when viewed.
Second and odor, the smell emitted by this thing is light and specific, not pungent, but not fragrant, just like the unique smell hidden in the world, you need to smell it carefully.
Furthermore, in terms of its boiling point, the value is quite high, and under normal pressure, it needs to be roasted at high temperature before it can be turned into gas. This property allows it to maintain a liquid state in a specific environment, as stable as a rock.
The melting point is also unique, and it needs to be in a lower temperature range to condense into a solid state, like winter ice, crystal clear but tough.
Its density is heavier than that of water. If it is poured into water, it will be like a stone sinking into an abyss, sinking straight down, showing its own weight.
In terms of solubility, among many organic solvents, it can find a safe place to live and blend with it, just like old friends reuniting and fitting each other.
The physical properties of this 2%2C3%2C4-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF, or in the field of chemical industry and scientific research, are of great significance and pave a unique way for many explorations and creations.
First of all, its appearance, at room temperature, is mostly colorless and transparent, like clear water, pure and free of variegated colors, and it makes people feel clear when viewed.
Second and odor, the smell emitted by this thing is light and specific, not pungent, but not fragrant, just like the unique smell hidden in the world, you need to smell it carefully.
Furthermore, in terms of its boiling point, the value is quite high, and under normal pressure, it needs to be roasted at high temperature before it can be turned into gas. This property allows it to maintain a liquid state in a specific environment, as stable as a rock.
The melting point is also unique, and it needs to be in a lower temperature range to condense into a solid state, like winter ice, crystal clear but tough.
Its density is heavier than that of water. If it is poured into water, it will be like a stone sinking into an abyss, sinking straight down, showing its own weight.
In terms of solubility, among many organic solvents, it can find a safe place to live and blend with it, just like old friends reuniting and fitting each other.
The physical properties of this 2%2C3%2C4-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF, or in the field of chemical industry and scientific research, are of great significance and pave a unique way for many explorations and creations.
What are the chemical properties of 2,3,4-trichlorobenzenesulfonyl chloride?
2% 2C3% 2C4-trifluorobenzoate ethyl ester is an organic compound with unique chemical properties. Its properties are stable, and it can react with strong oxidants and strong bases.
When it encounters strong oxidants, some chemical bonds in 2% 2C3% 2C4-trifluorobenzoate may be oxidized. For example, the electron cloud density around the carbon and oxygen double bonds in its ester groups is high, or it becomes an oxidant to attack the target, causing the structure of the ester groups to change and generating corresponding oxidation products.
When it encounters strong bases, 2% 2C3% 2C4-trifluorobenzoate ethyl ester will undergo hydrolysis reaction. The hydroxide ion provided by the strong base has strong nucleophilicity and attacks the partially positively charged carbon atoms in the ester group. After a series of intermediate states, the ester bond breaks to form 2% 2C3% 2C4-trifluorobenzoic acid and alcohols.
Because of its fluorine atom, 2% 2C3% 2C4-trifluorobenzoic acid ethyl ester has certain fat solubility and chemical stability. The fluorine atom has high electronegativity and high C-F bond energy, which endows the compound with special physical and chemical properties, such as hot topic stability and chemical inertness.
In addition, the benzene ring in 2% 2C3% 2C4-trifluorobenzoic acid ethyl ester has aromatic properties and can undergo electrophilic substitution reactions. The electron cloud density distribution on the benzene ring makes it easy for electrophilic reagents to attack the benzene ring and form various substitution products.
2% 2C3% 2C4 -ethyl trifluorobenzoate has rich chemical properties and has important application value in organic synthesis and other fields. It can be used as a key intermediate for the preparation of organic compounds such as drugs and materials with specific properties.
When it encounters strong oxidants, some chemical bonds in 2% 2C3% 2C4-trifluorobenzoate may be oxidized. For example, the electron cloud density around the carbon and oxygen double bonds in its ester groups is high, or it becomes an oxidant to attack the target, causing the structure of the ester groups to change and generating corresponding oxidation products.
When it encounters strong bases, 2% 2C3% 2C4-trifluorobenzoate ethyl ester will undergo hydrolysis reaction. The hydroxide ion provided by the strong base has strong nucleophilicity and attacks the partially positively charged carbon atoms in the ester group. After a series of intermediate states, the ester bond breaks to form 2% 2C3% 2C4-trifluorobenzoic acid and alcohols.
Because of its fluorine atom, 2% 2C3% 2C4-trifluorobenzoic acid ethyl ester has certain fat solubility and chemical stability. The fluorine atom has high electronegativity and high C-F bond energy, which endows the compound with special physical and chemical properties, such as hot topic stability and chemical inertness.
In addition, the benzene ring in 2% 2C3% 2C4-trifluorobenzoic acid ethyl ester has aromatic properties and can undergo electrophilic substitution reactions. The electron cloud density distribution on the benzene ring makes it easy for electrophilic reagents to attack the benzene ring and form various substitution products.
2% 2C3% 2C4 -ethyl trifluorobenzoate has rich chemical properties and has important application value in organic synthesis and other fields. It can be used as a key intermediate for the preparation of organic compounds such as drugs and materials with specific properties.
What is the preparation method of 2,3,4-trichlorobenzenesulfonyl chloride?
To prepare 2,3,4-trifluorobenzoyl fluoride, the method is as follows:
Take 2,3,4-trifluorobenzoic acid as the starting material. Place this acid in a suitable reactor, use anhydrous hydrogen fluoride as the solvent and fluorination reagent, and add an appropriate amount of catalyst, such as antimony pentachloride. The reactor is tightly sealed and maintains a low temperature environment, about -10 ° C to 0 ° C. Slowly introduce fluorine-containing gases, such as boron trifluoride, to promote the reaction.
During the reaction, pay close attention to changes in temperature and pressure to ensure a smooth reaction. After the reaction is completed, pour the reaction mixture into ice water to stop the reaction. Subsequently, organic solvents such as dichloromethane are used for extraction, and the extraction solution is dried with anhydrous sodium sulfate to remove water. After that, the method of reduced pressure distillation is used to collect fractions with suitable boiling points to obtain 2,3,4-trifluorobenzoyl fluoride products.
Another way is to convert 2,3,4-trifluorobenzoic acid into the corresponding acid chloride, such as reacting with sulfoxide chloride, heating and refluxing, until the reaction is complete, to remove excess sulfoxide chloride. The resulting acid chloride is then reacted with anhydrous potassium fluoride in a polar aprotic solvent such as N, N-dimethylformamide, and heated to an appropriate temperature, such as 80 ° C to 100 ° C, for a period of time. After the reaction is completed, 2,3,4-trifluorobenzoyl fluoride can also be prepared after post-processing, such as filtration, extraction, distillation and other steps.
These two methods have their own advantages and disadvantages. The former reaction step is relatively simple, but special reaction conditions and equipment are required; although the latter step is slightly complicated, it is more common and easy to operate. When actually preparing, choose the best one according to the specific situation.
Take 2,3,4-trifluorobenzoic acid as the starting material. Place this acid in a suitable reactor, use anhydrous hydrogen fluoride as the solvent and fluorination reagent, and add an appropriate amount of catalyst, such as antimony pentachloride. The reactor is tightly sealed and maintains a low temperature environment, about -10 ° C to 0 ° C. Slowly introduce fluorine-containing gases, such as boron trifluoride, to promote the reaction.
During the reaction, pay close attention to changes in temperature and pressure to ensure a smooth reaction. After the reaction is completed, pour the reaction mixture into ice water to stop the reaction. Subsequently, organic solvents such as dichloromethane are used for extraction, and the extraction solution is dried with anhydrous sodium sulfate to remove water. After that, the method of reduced pressure distillation is used to collect fractions with suitable boiling points to obtain 2,3,4-trifluorobenzoyl fluoride products.
Another way is to convert 2,3,4-trifluorobenzoic acid into the corresponding acid chloride, such as reacting with sulfoxide chloride, heating and refluxing, until the reaction is complete, to remove excess sulfoxide chloride. The resulting acid chloride is then reacted with anhydrous potassium fluoride in a polar aprotic solvent such as N, N-dimethylformamide, and heated to an appropriate temperature, such as 80 ° C to 100 ° C, for a period of time. After the reaction is completed, 2,3,4-trifluorobenzoyl fluoride can also be prepared after post-processing, such as filtration, extraction, distillation and other steps.
These two methods have their own advantages and disadvantages. The former reaction step is relatively simple, but special reaction conditions and equipment are required; although the latter step is slightly complicated, it is more common and easy to operate. When actually preparing, choose the best one according to the specific situation.
What are the precautions for using 2,3,4-trichlorobenzenesulfonyl chloride?
2%2C3%2C4-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF%E7%B1%BB%E5%8F%98%E6%80%A7%E6%9C%89%E6%9D%80%E6%80%A7%E4%B8%8E%E6%B0%AF%E6%80%A7%E4%B8%A4%E7%A7%8D%EF%BC%8C%E5%9C%A8%E4%BD%BF%E7%94%A8%E8%BF%87%E7%A8%8B%E4%B8%AD%EF%BC%8C%E5%BF%85%E9%A1%BB%E6%B3%A8%E6%84%8F%E4%B8%8B%E5%88%97%E4%BA%8B%E9%A1%B9%EF%BC%9A
First, this medicine is highly volatile. When placed in an exposed place or in a high temperature environment, it is easy to evaporate and dissipate, causing the drug to weaken. Therefore, it needs to be stored in a cool and dry place, away from fire and heat sources. For example, the "Compendium of Materia Medica" records all medicine storage methods, which are heavily sealed and protected from heat. The same is true for this medicine.
Second, it irritates the skin and mucous membranes. When using, if you accidentally touch the skin, you should quickly rinse with a lot of water; if it enters the eyes, you need to rinse immediately and seek medical treatment. In the past, a craftsman accidentally touched powerful medicines in the eyes, causing eye diseases, so you need to pay great attention to such stimuli.
Third, 2%2C3%2C4-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF%E6%9C%89%E6%9D%80%E6%80%A7, when using it, it should be avoided to co-store or mix with strong oxidants, strong acids, etc. Because the two meet, or cause violent chemical reactions, causing explosions, burning and other dangers. Ancient alchemists combined medicine, well aware of the drug resistance, mixing medicine carelessly will cause disaster, the same is true.
Fourth, the use of this medicine must follow the doctor's instructions or product instructions. Different diseases and different groups of people, the dosage and usage are different. If you increase or decrease the dose or change the usage without authorization, it may be difficult to achieve the expected efficacy, or even cause adverse reactions. If a doctor in ancient times uses medicine, the dosage must be considered according to the patient's physique and the severity of the disease, and the same is true for this medicine.
First, this medicine is highly volatile. When placed in an exposed place or in a high temperature environment, it is easy to evaporate and dissipate, causing the drug to weaken. Therefore, it needs to be stored in a cool and dry place, away from fire and heat sources. For example, the "Compendium of Materia Medica" records all medicine storage methods, which are heavily sealed and protected from heat. The same is true for this medicine.
Second, it irritates the skin and mucous membranes. When using, if you accidentally touch the skin, you should quickly rinse with a lot of water; if it enters the eyes, you need to rinse immediately and seek medical treatment. In the past, a craftsman accidentally touched powerful medicines in the eyes, causing eye diseases, so you need to pay great attention to such stimuli.
Third, 2%2C3%2C4-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF%E6%9C%89%E6%9D%80%E6%80%A7, when using it, it should be avoided to co-store or mix with strong oxidants, strong acids, etc. Because the two meet, or cause violent chemical reactions, causing explosions, burning and other dangers. Ancient alchemists combined medicine, well aware of the drug resistance, mixing medicine carelessly will cause disaster, the same is true.
Fourth, the use of this medicine must follow the doctor's instructions or product instructions. Different diseases and different groups of people, the dosage and usage are different. If you increase or decrease the dose or change the usage without authorization, it may be difficult to achieve the expected efficacy, or even cause adverse reactions. If a doctor in ancient times uses medicine, the dosage must be considered according to the patient's physique and the severity of the disease, and the same is true for this medicine.
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