Linshang Chemical
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2,3,5,6-Tetrafluoro-1,4-Bis(Chloromethyl)Benzene
Linshang Chemical
|
HS Code |
896612 |
| Chemical Formula | C8H4Cl2F4 |
| Molecular Weight | 261.016 g/mol |
| Appearance | Typically a colorless to light - colored liquid |
| Boiling Point | Data may vary, but around 200 - 220 °C under normal pressure |
| Density | Specific value depends on temperature, but generally heavier than water |
| Solubility | Soluble in some organic solvents, poor solubility in water |
| Vapor Pressure | Relatively low vapor pressure at room temperature |
| Stability | Stable under normal storage conditions, but may react with strong oxidizing agents |
As an accredited 2,3,5,6-Tetrafluoro-1,4-Bis(Chloromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of 2,3,5,6 - tetrafluoro - 1,4 - bis(chloromethyl)benzene in sealed chemical - grade container. |
| Storage | 2,3,5,6 - tetrafluoro - 1,4 - bis(chloromethyl)benzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly sealed container to prevent leakage and exposure to air or moisture, which could potentially lead to chemical reactions. |
| Shipping | 2,3,5,6 - tetrafluoro - 1,4 - bis(chloromethyl)benzene is shipped in sealed, corrosion - resistant containers. It follows strict hazardous chemical shipping regulations to ensure safety during transportation, avoiding exposure and potential risks. |
Competitive 2,3,5,6-Tetrafluoro-1,4-Bis(Chloromethyl)Benzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2,3,5,6-Tetrafluoro-1,4-Bis(Chloromethyl)Benzene in China?
As a trusted 2,3,5,6-Tetrafluoro-1,4-Bis(Chloromethyl)Benzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2,3,5,6-Tetrafluoro-1,4-Bis(Chloromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene?
2% 2C3% 2C5% 2C6 - tetrafluoro - 1% 2C4 - bis%28chloromethyl%29benzene is 2,3,5,6 - tetrafluoro - 1,4 - bis (chloromethyl) benzene, which is widely used.
In the field of organic synthesis, it is an important intermediate. Due to its structure containing chloromethyl and fluorine atoms, chloromethyl is highly active and can be converted by various chemical reactions, such as nucleophilic substitution. Chloromethyl of halogenated hydrocarbons can react with nucleophiles containing hydroxyl and amino groups to form compounds with different structures such as ethers and amines. This property enables 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene to participate in the synthesis of complex organic molecules, in the field of medicinal chemistry, to help build drug molecular structures with specific biological activities, laying the foundation for the development of new drugs.
In the field of materials science, it also has important applications. Due to the introduction of fluorine atoms, materials are endowed with special properties. Fluorine atoms have high electronegativity, which can enhance the chemical stability, corrosion resistance and weather resistance of materials. Polymer materials prepared from them may have excellent properties. They can be used as high-performance structural materials or functional materials in fields such as aerospace and electronics that require strict material properties, such as the manufacture of special protective coatings, electronic packaging materials, etc.
In addition, in the fine chemical industry, 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene is used to synthesize high-end fine chemicals, such as special catalysts, surfactants, etc. Special catalysts can improve reaction efficiency and selectivity in specific chemical reactions, while surfactants can improve the surface properties of substances, and are widely used in daily chemical, textile and other industries.
To sum up, 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene plays a key role in organic synthesis, materials science, fine chemicals and other fields due to its unique structure and properties. It is of great significance to promote technological development and product innovation in various industries.
In the field of organic synthesis, it is an important intermediate. Due to its structure containing chloromethyl and fluorine atoms, chloromethyl is highly active and can be converted by various chemical reactions, such as nucleophilic substitution. Chloromethyl of halogenated hydrocarbons can react with nucleophiles containing hydroxyl and amino groups to form compounds with different structures such as ethers and amines. This property enables 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene to participate in the synthesis of complex organic molecules, in the field of medicinal chemistry, to help build drug molecular structures with specific biological activities, laying the foundation for the development of new drugs.
In the field of materials science, it also has important applications. Due to the introduction of fluorine atoms, materials are endowed with special properties. Fluorine atoms have high electronegativity, which can enhance the chemical stability, corrosion resistance and weather resistance of materials. Polymer materials prepared from them may have excellent properties. They can be used as high-performance structural materials or functional materials in fields such as aerospace and electronics that require strict material properties, such as the manufacture of special protective coatings, electronic packaging materials, etc.
In addition, in the fine chemical industry, 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene is used to synthesize high-end fine chemicals, such as special catalysts, surfactants, etc. Special catalysts can improve reaction efficiency and selectivity in specific chemical reactions, while surfactants can improve the surface properties of substances, and are widely used in daily chemical, textile and other industries.
To sum up, 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene plays a key role in organic synthesis, materials science, fine chemicals and other fields due to its unique structure and properties. It is of great significance to promote technological development and product innovation in various industries.
What are the physical properties of 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene
2% 2C3% 2C5% 2C6 - tetrafluoro - 1% 2C4 - bis%28chloromethyl%29benzene is 2,3,5,6 - tetrafluoro - 1,4 - bis (chloromethyl) benzene. The physical properties of this substance are very important, related to its application in various scenarios.
Its appearance is often colorless to light yellow liquid form. Looking at its color, you can know its purity and the presence or absence of impurities. This liquid has good fluidity, smooth touch, and high stability at room temperature and pressure. It is not easy to undergo violent chemical changes on its own.
When it comes to odor, 2,3,5,6 - tetrafluoro - 1,4 - bis (chloromethyl) benzene has a special irritating odor. This smell is strong and unique, even if the content in the air is very small, it can be detected by people. If you smell it, the nasal cavity and respiratory tract may feel uncomfortable, so you need to pay special attention to ventilation conditions when using it to prevent human damage.
Its boiling point is also one of the key physical properties. After determination, the boiling point is in a specific temperature range. This boiling point characteristic is crucial in chemical operations such as separation and purification. By precisely controlling the temperature, the substance can be separated from other substances according to the difference in boiling point, and the purpose of purification can be achieved.
Melting point also has its fixed value. When the temperature drops below the melting point, the substance gradually changes from liquid to solid. The determination of this solid-liquid transition temperature is of great significance for the setting of storage and transportation conditions. Knowing the melting point, you can choose a suitable temperature environment to ensure the stability of the material form and not affect its quality due to temperature fluctuations.
In terms of solubility, 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene has good solubility in some organic solvents, such as common aromatic hydrocarbon organic solvents. However, in water, its solubility is very poor and almost insoluble. This difference in solubility provides a basis for its application in different chemical reaction systems, and also affects the choice of reaction medium and the design of subsequent product separation processes.
Density is also a physical property that cannot be ignored. Its density value is specific, and it is an important parameter in the measurement of materials in chemical production and the calculation of the loading capacity of the reactor. Only by accurately grasping the density can we ensure the accuracy and efficiency of the production process.
Its appearance is often colorless to light yellow liquid form. Looking at its color, you can know its purity and the presence or absence of impurities. This liquid has good fluidity, smooth touch, and high stability at room temperature and pressure. It is not easy to undergo violent chemical changes on its own.
When it comes to odor, 2,3,5,6 - tetrafluoro - 1,4 - bis (chloromethyl) benzene has a special irritating odor. This smell is strong and unique, even if the content in the air is very small, it can be detected by people. If you smell it, the nasal cavity and respiratory tract may feel uncomfortable, so you need to pay special attention to ventilation conditions when using it to prevent human damage.
Its boiling point is also one of the key physical properties. After determination, the boiling point is in a specific temperature range. This boiling point characteristic is crucial in chemical operations such as separation and purification. By precisely controlling the temperature, the substance can be separated from other substances according to the difference in boiling point, and the purpose of purification can be achieved.
Melting point also has its fixed value. When the temperature drops below the melting point, the substance gradually changes from liquid to solid. The determination of this solid-liquid transition temperature is of great significance for the setting of storage and transportation conditions. Knowing the melting point, you can choose a suitable temperature environment to ensure the stability of the material form and not affect its quality due to temperature fluctuations.
In terms of solubility, 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene has good solubility in some organic solvents, such as common aromatic hydrocarbon organic solvents. However, in water, its solubility is very poor and almost insoluble. This difference in solubility provides a basis for its application in different chemical reaction systems, and also affects the choice of reaction medium and the design of subsequent product separation processes.
Density is also a physical property that cannot be ignored. Its density value is specific, and it is an important parameter in the measurement of materials in chemical production and the calculation of the loading capacity of the reactor. Only by accurately grasping the density can we ensure the accuracy and efficiency of the production process.
What are the chemical properties of 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene
2% 2C3% 2C5% 2C6 - tetrafluoro - 1% 2C4 - bis%28chloromethyl%29benzene. Its molecule contains benzene, which is superimposed on dichloromethyl, and has another tetrafluoro atom on it. The chemical properties of this compound are very special.
Its chemical properties are first related to chloromethyl groups. Chloromethyl groups are active and can be involved in general antibodies. If the nucleus replaces the antibodies, the atom of the element (chlorine) can be relocated by the nucleus. If it encounters antibodies, chloromethyl groups can be hydrolyzed, chlorine groups, and alcohol derivatives of the raw phase. This antidote process is that the nucleus attacks the carbon atom of the chloromethyl group, and the chlorine child is removed to form a new carbon atom.
Furthermore, the fluorine atom also has its influence. Fluorine atoms have high stability, which can cause the density of benzene sub-clouds to change. The anti-activity and anti-orientation of benzene are restricted by it. For example, in the anti-substitution anti-reaction, the absorber effect of fluorine atoms can reduce the density of benzene sub-clouds, and the anti-activity is limited to benzene; and because of its location resistance and anti-effect, the specific location of the attack is specific, and it is mostly related to the high density of the sub-cloud on the benzene.
Because of its polyfluorine atoms, the qualitative properties of compounds increase. Fluorine-carbon energy is high, so that molecules can crack. This characteristic is in the field of material science and other fields, and can be used to improve the resistance of phase materials to corrosion and high resistance.
It can be used as an important medium in the synthesis of organic compounds. By virtue of the anti-activity of chloromethyl chloride, it can generate a wide range of carbon-carbon and carbon-atomic compounds, and has a promising future in the synthesis of organic compounds, materials, and other fields.
Its chemical properties are first related to chloromethyl groups. Chloromethyl groups are active and can be involved in general antibodies. If the nucleus replaces the antibodies, the atom of the element (chlorine) can be relocated by the nucleus. If it encounters antibodies, chloromethyl groups can be hydrolyzed, chlorine groups, and alcohol derivatives of the raw phase. This antidote process is that the nucleus attacks the carbon atom of the chloromethyl group, and the chlorine child is removed to form a new carbon atom.
Furthermore, the fluorine atom also has its influence. Fluorine atoms have high stability, which can cause the density of benzene sub-clouds to change. The anti-activity and anti-orientation of benzene are restricted by it. For example, in the anti-substitution anti-reaction, the absorber effect of fluorine atoms can reduce the density of benzene sub-clouds, and the anti-activity is limited to benzene; and because of its location resistance and anti-effect, the specific location of the attack is specific, and it is mostly related to the high density of the sub-cloud on the benzene.
Because of its polyfluorine atoms, the qualitative properties of compounds increase. Fluorine-carbon energy is high, so that molecules can crack. This characteristic is in the field of material science and other fields, and can be used to improve the resistance of phase materials to corrosion and high resistance.
It can be used as an important medium in the synthesis of organic compounds. By virtue of the anti-activity of chloromethyl chloride, it can generate a wide range of carbon-carbon and carbon-atomic compounds, and has a promising future in the synthesis of organic compounds, materials, and other fields.
What are the synthesis methods of 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene
2% 2C3% 2C5% 2C6 - tetrafluoro - 1% 2C4 - bis%28chloromethyl%29benzene that is, 2,3,5,6 - tetrafluoro - 1,4 - bis (chloromethyl) benzene. The synthesis method is as follows:
The starting material is often terephthalol. It is first halogenated, usually using a chlorination reagent such as sulfuryl chloride (SOCl ²). Under suitable conditions, terephthalol reacts with sulfuryl chloride, and the hydroxyl group is replaced by a chlorine atom to generate 1,4 - bis (chloromethyl) benzene. In this step, sulfuryl chloride is not only used as a chlorination reagent, but its by-products sulfur dioxide and hydrogen chloride gas are easily volatilized and removed, which is conducive to the forward reaction.
Then, 1,4-bis (chloromethyl) benzene is fluorinated. Anhydrous potassium fluoride (KF) can be used as a fluorination reagent, but this reaction needs to be carried out in an aprotic polar solvent, such as dimethyl sulfoxide (DMSO). During the reaction, the reaction temperature and time need to be controlled because the nucleophilicity of fluoride ions is relatively weak, and the chloromethyl on the benzene ring has a certain blunt effect on the benzene ring. Generally, under heating conditions, the temperature of the reaction system is maintained between 150-200 ° C, and the reaction continues for several hours, which prompts the hydrogen atoms at specific positions on the benzene ring to be gradually replaced by fluorine atoms, and finally generates 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene.
Another possible synthesis path is to use p-dichloromethylbenzene as the starting material, and first carry out the electrophilic substitution fluorination reaction on the benzene ring. Using strong fluorinating reagents such as Selectfluor, and under the action of suitable catalysts such as Lewis acid (such as aluminum trichloride AlCl), fluorine atoms are introduced into the benzene ring. Then the chloromethyl group is modified, such as first converting the chloromethyl group into the corresponding alcohol hydroxyl group, and then converting the hydroxyl group into the chlorine atom with a suitable chlorination reagent, so as to obtain the target product. However, this route step is relatively cumbersome, and in the step of introducing fluorine atoms, the reaction conditions need to be precisely controlled to avoid side reactions such as multiple substitutions.
The starting material is often terephthalol. It is first halogenated, usually using a chlorination reagent such as sulfuryl chloride (SOCl ²). Under suitable conditions, terephthalol reacts with sulfuryl chloride, and the hydroxyl group is replaced by a chlorine atom to generate 1,4 - bis (chloromethyl) benzene. In this step, sulfuryl chloride is not only used as a chlorination reagent, but its by-products sulfur dioxide and hydrogen chloride gas are easily volatilized and removed, which is conducive to the forward reaction.
Then, 1,4-bis (chloromethyl) benzene is fluorinated. Anhydrous potassium fluoride (KF) can be used as a fluorination reagent, but this reaction needs to be carried out in an aprotic polar solvent, such as dimethyl sulfoxide (DMSO). During the reaction, the reaction temperature and time need to be controlled because the nucleophilicity of fluoride ions is relatively weak, and the chloromethyl on the benzene ring has a certain blunt effect on the benzene ring. Generally, under heating conditions, the temperature of the reaction system is maintained between 150-200 ° C, and the reaction continues for several hours, which prompts the hydrogen atoms at specific positions on the benzene ring to be gradually replaced by fluorine atoms, and finally generates 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene.
Another possible synthesis path is to use p-dichloromethylbenzene as the starting material, and first carry out the electrophilic substitution fluorination reaction on the benzene ring. Using strong fluorinating reagents such as Selectfluor, and under the action of suitable catalysts such as Lewis acid (such as aluminum trichloride AlCl), fluorine atoms are introduced into the benzene ring. Then the chloromethyl group is modified, such as first converting the chloromethyl group into the corresponding alcohol hydroxyl group, and then converting the hydroxyl group into the chlorine atom with a suitable chlorination reagent, so as to obtain the target product. However, this route step is relatively cumbersome, and in the step of introducing fluorine atoms, the reaction conditions need to be precisely controlled to avoid side reactions such as multiple substitutions.
What are the precautions for storing and transporting 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene?
2% 2C3% 2C5% 2C6 - tetrafluoro - 1% 2C4 - bis%28chloromethyl%29benzene is a chemical substance, the Chinese name is or 2,3,5,6 - tetrafluoro - 1,4 - bis (chloromethyl) benzene. When storing and transporting this substance, many matters need to be paid attention to.
First, the storage place must be dry and well ventilated. Because it may have certain chemical activity, the humid environment can easily cause chemical reactions to occur and cause it to deteriorate. If the storage place is humid, water vapor may interact with the substance, damaging its chemical structure and purity. Therefore, the warehouse should be kept dry, and the humidity should be controlled at a low level.
Second, keep away from fire and heat sources. This substance may be flammable, in case of open flame, hot topic or cause combustion or even explosion. During transportation, the transportation vehicle should not be close to high temperature areas or places with fire sources; when storing, it should also keep a safe distance from fire and heat sources.
Third, it should be stored separately from oxidants, acids, alkalis, etc. Due to its chemical properties, contact with these substances or trigger violent chemical reactions, resulting in dangerous conditions. If it encounters with strong oxidants or triggers an oxidation reaction, the temperature will rise sharply and the pressure will increase.
Fourth, the storage container must be well sealed. To prevent substances from evaporating and escaping, polluting the environment, and to avoid reaction with air components. When transporting, choose suitable packaging materials to ensure that the container is not damaged or leaked during transportation bumps.
Fifth, light handling is required during handling. To prevent damage to packaging and containers and leakage of substances. Operators should wear appropriate protective equipment to avoid direct contact with the substance.
In short, 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene must be stored and transported in strict accordance with safety regulations to ensure the safety of personnel and the environment is not polluted.
First, the storage place must be dry and well ventilated. Because it may have certain chemical activity, the humid environment can easily cause chemical reactions to occur and cause it to deteriorate. If the storage place is humid, water vapor may interact with the substance, damaging its chemical structure and purity. Therefore, the warehouse should be kept dry, and the humidity should be controlled at a low level.
Second, keep away from fire and heat sources. This substance may be flammable, in case of open flame, hot topic or cause combustion or even explosion. During transportation, the transportation vehicle should not be close to high temperature areas or places with fire sources; when storing, it should also keep a safe distance from fire and heat sources.
Third, it should be stored separately from oxidants, acids, alkalis, etc. Due to its chemical properties, contact with these substances or trigger violent chemical reactions, resulting in dangerous conditions. If it encounters with strong oxidants or triggers an oxidation reaction, the temperature will rise sharply and the pressure will increase.
Fourth, the storage container must be well sealed. To prevent substances from evaporating and escaping, polluting the environment, and to avoid reaction with air components. When transporting, choose suitable packaging materials to ensure that the container is not damaged or leaked during transportation bumps.
Fifth, light handling is required during handling. To prevent damage to packaging and containers and leakage of substances. Operators should wear appropriate protective equipment to avoid direct contact with the substance.
In short, 2,3,5,6-tetrafluoro-1,4-bis (chloromethyl) benzene must be stored and transported in strict accordance with safety regulations to ensure the safety of personnel and the environment is not polluted.
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