Linshang Chemical
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2,3,5-Trichloro-4-Fluoronitrobenzene
Linshang Chemical
|
HS Code |
354988 |
| Chemical Formula | C6HCl3FNO2 |
| Molar Mass | 230.43 g/mol |
| Appearance | Solid |
| Color | Pale yellow to light brown |
| Odor | Pungent |
| Melting Point | 74 - 78 °C |
| Boiling Point | 247 - 249 °C |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents |
| Stability | Stable under normal conditions |
| Hazardous Decomposition Products | May produce toxic fumes of hydrogen chloride, hydrogen fluoride, nitrogen oxides |
As an accredited 2,3,5-Trichloro-4-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 250g of 2,3,5 - trichloro - 4 - fluoronitrobenzene packaged in a sealed glass bottle. |
| Storage | 2,3,5 - trichloro - 4 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It should be stored separately from oxidizing agents, reducing agents, and other incompatible substances. Keep containers tightly closed to prevent leakage, in a place inaccessible to children. |
| Shipping | 2,3,5 - trichloro - 4 - fluoronitrobenzene is shipped in sealed, corrosion - resistant containers. Special care is taken to prevent leakage during transit as it's a chemical. Shipments follow strict hazardous material regulations. |
Competitive 2,3,5-Trichloro-4-Fluoronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2,3,5-Trichloro-4-Fluoronitrobenzene in China?
As a trusted 2,3,5-Trichloro-4-Fluoronitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
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Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2,3,5-Trichloro-4-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2,3,5-trichloro-4-fluoronitrobenzene?
2% 2C3% 2C5-trifluoro-4-cyanophenylboron, this substance has a wide range of uses. In the field of pharmaceutical synthesis, it can be used as a key intermediate. In the creation process of many new anti-cancer drugs, it can effectively build a specific molecular structure. With its unique chemical activity, it participates in the construction of key check points of drug molecules, and helps to improve the binding ability of drugs to targets, thereby enhancing drug efficacy.
In the field of materials science, it also plays an important role. In the preparation of high-performance organic optoelectronic materials, the introduction of this substance can optimize the electron transport properties of the materials. Due to its special fluorine atom and cyanyl structure, it can adjust the energy level structure of the material, allowing electrons to travel more smoothly inside the material, thereby improving the luminous efficiency and stability of optoelectronic devices such as organic Light Emitting Diode (OLED).
In addition, in organic synthetic chemistry, it is often used as an organoboron reagent. In various coupling reactions, it reacts with other organic compounds as an electrophilic reagent to form important chemical bonds such as carbon-carbon bonds and carbon-heteroatomic bonds, which greatly enriches the synthesis path of organic compounds and provides a powerful means for the synthesis of complex and diverse organic molecules.
In the field of materials science, it also plays an important role. In the preparation of high-performance organic optoelectronic materials, the introduction of this substance can optimize the electron transport properties of the materials. Due to its special fluorine atom and cyanyl structure, it can adjust the energy level structure of the material, allowing electrons to travel more smoothly inside the material, thereby improving the luminous efficiency and stability of optoelectronic devices such as organic Light Emitting Diode (OLED).
In addition, in organic synthetic chemistry, it is often used as an organoboron reagent. In various coupling reactions, it reacts with other organic compounds as an electrophilic reagent to form important chemical bonds such as carbon-carbon bonds and carbon-heteroatomic bonds, which greatly enriches the synthesis path of organic compounds and provides a powerful means for the synthesis of complex and diverse organic molecules.
What are the physical properties of 2,3,5-trichloro-4-fluoronitrobenzene?
2% 2C3% 2C5 -trifluoro-4 -cyanobenzene is an organic compound. Its physical properties are particularly important and have applications in many fields. The following is a detailed description of Jun.
Looking at its appearance, under room temperature and pressure, this compound is often in the state of white to light yellow crystalline powder, with a fine texture, like fine snow, and its purpose is clear and discernible.
When it comes to the melting point, the melting point of this substance is in a specific range, about [X] ° C. The characteristics of the melting point make the compound gradually melt from solid to liquid at the corresponding temperature, and this transformation process has a great impact on its processing and application.
Boiling point is also a key physical property. In atmospheric pressure environment, its boiling point is about [X] ℃. When the temperature rises to the boiling point, the compound is converted from liquid to gaseous state, which is of great significance in separation and purification processes.
In terms of solubility, the compound exhibits good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), and can be miscible with these solvents in a certain proportion, just like water emulsion. However, in water, its solubility is very small and it is difficult to dissolve with water. This property helps to separate and extract it according to demand.
Density is also a physical property that cannot be ignored, and its density is about [X] g/cm ³. This value reflects the mass per unit volume of the compound, which needs to be considered in terms of storage, transportation, and the proportion of related chemical reaction materials.
In addition, the compound has certain stability. However, under certain conditions, such as high temperature, strong acid and alkali environment, its structure may change, and its chemical properties will also change.
In summary, the physical properties of 2% 2C3% 2C5-trifluoro-4-cyanobenzene, such as appearance, melting point, boiling point, solubility, density, and stability, have a profound impact on its application in chemical, pharmaceutical, and other fields, and must be paid attention to in the relevant process design and operation.
Looking at its appearance, under room temperature and pressure, this compound is often in the state of white to light yellow crystalline powder, with a fine texture, like fine snow, and its purpose is clear and discernible.
When it comes to the melting point, the melting point of this substance is in a specific range, about [X] ° C. The characteristics of the melting point make the compound gradually melt from solid to liquid at the corresponding temperature, and this transformation process has a great impact on its processing and application.
Boiling point is also a key physical property. In atmospheric pressure environment, its boiling point is about [X] ℃. When the temperature rises to the boiling point, the compound is converted from liquid to gaseous state, which is of great significance in separation and purification processes.
In terms of solubility, the compound exhibits good solubility in organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), and can be miscible with these solvents in a certain proportion, just like water emulsion. However, in water, its solubility is very small and it is difficult to dissolve with water. This property helps to separate and extract it according to demand.
Density is also a physical property that cannot be ignored, and its density is about [X] g/cm ³. This value reflects the mass per unit volume of the compound, which needs to be considered in terms of storage, transportation, and the proportion of related chemical reaction materials.
In addition, the compound has certain stability. However, under certain conditions, such as high temperature, strong acid and alkali environment, its structure may change, and its chemical properties will also change.
In summary, the physical properties of 2% 2C3% 2C5-trifluoro-4-cyanobenzene, such as appearance, melting point, boiling point, solubility, density, and stability, have a profound impact on its application in chemical, pharmaceutical, and other fields, and must be paid attention to in the relevant process design and operation.
Is the chemical property of 2,3,5-trichloro-4-fluoronitrobenzene stable?
The chemical properties of 2% 2C3% 2C5-trifluoro-4-cyanobenzene are relatively stable. From the structural point of view, the trifluoro group connected to the cyanyl group on the benzene ring endows it with unique electronic effects and steric resistance. The electronegativity of the fluorine atom is extremely strong, and the trifluoro group will strongly attract electrons, which reduces the electron cloud density of the benzene ring, which enhances the stability of the compound to a certain extent. As a strong electron-absorbing group, the cyanide group further adjusts the electron distribution of the benzene ring, and it has a certain stability. It interacts with the benzene ring conjugate system to stabilize the entire molecular structure.
Under common chemical reaction conditions, it is not easy to undergo general electrophilic substitution reactions, because the reduction of electron cloud density of benzene ring is not conducive to the attack of electrophilic reagents. In terms of thermal stability, due to the conjugate system formed by these groups with benzene ring and the special bond energy of fluorine atoms, the compound can maintain structural stability at higher temperatures and is not easy to decompose.
However, if it encounters strong oxidants or under specific extreme conditions, its cyanide group may undergo reactions such as hydrolysis, which will destroy the original structural stability of the molecule. However, in conventional laboratory and industrial environments, 2% 2C3% 2C5-trifluoro-4-cyanobenzene usually exhibits good chemical stability without specific excitation conditions.
Under common chemical reaction conditions, it is not easy to undergo general electrophilic substitution reactions, because the reduction of electron cloud density of benzene ring is not conducive to the attack of electrophilic reagents. In terms of thermal stability, due to the conjugate system formed by these groups with benzene ring and the special bond energy of fluorine atoms, the compound can maintain structural stability at higher temperatures and is not easy to decompose.
However, if it encounters strong oxidants or under specific extreme conditions, its cyanide group may undergo reactions such as hydrolysis, which will destroy the original structural stability of the molecule. However, in conventional laboratory and industrial environments, 2% 2C3% 2C5-trifluoro-4-cyanobenzene usually exhibits good chemical stability without specific excitation conditions.
What are the preparation methods of 2,3,5-trichloro-4-fluoronitrobenzene?
To prepare 2% 2C3% 2C5-trifluoro-4-cyanophenyl, the ancient method may have the following numbers.
First, the halogenation method can be used. First take the appropriate phenyl derivative, add a halogenating agent, so that fluorine atoms are introduced at a specific position. For example, starting with benzene containing a suitable substituent, choose a suitable halogenating reagent, and under precise temperature control, time adjustment and catalyst assistance, the fluorine atoms gradually enter the benzene ring to achieve the structure of 2% 2C3% 2C5-trifluoro. After cyanylation, the cyanyl group is introduced into the target check point. Or use a cyanide reagent, in a specific reaction environment, to promote the cyanyl group to replace the corresponding group, and obtain 2% 2C3% 2C5-trifluoro-4-cyanophenyl group.
Second, the method of functional group conversion can be adopted. Find a phenyl compound containing multiple convertible functional groups, and first modify some of its functional groups to gradually form a fluorinated structure. For example, the existing functional group on the benzene ring is changed into a group that can be easily fluorinated through a series of reactions, and then the fluorination reaction is carried out. When the fluorine atom is in place, it is skillfully converted to make another functional group into a cyano group. This process requires strict observation of the reaction conditions at each step to make the conversion accurate and efficient.
Third, it may be formed by cyclization. Take a compound containing a specific carbon chain and functional group, make it cyclized, and construct the prototype of the benzene ring. At the time of cyclization, it may already contain some fluorine atoms, or reserve a check point that can introduce fluorine and cyano groups. After cyclization, it is modified to introduce the remaining fluorine atoms and cyano groups. This approach requires a deep understanding of the cyclization reaction mechanism and the ability to precisely design the structure of the starting compound in order to achieve the goal.
All these production methods require craftsmen to study the principles of the reaction and control the conditions to achieve the purity and abundance of the prepared material.
First, the halogenation method can be used. First take the appropriate phenyl derivative, add a halogenating agent, so that fluorine atoms are introduced at a specific position. For example, starting with benzene containing a suitable substituent, choose a suitable halogenating reagent, and under precise temperature control, time adjustment and catalyst assistance, the fluorine atoms gradually enter the benzene ring to achieve the structure of 2% 2C3% 2C5-trifluoro. After cyanylation, the cyanyl group is introduced into the target check point. Or use a cyanide reagent, in a specific reaction environment, to promote the cyanyl group to replace the corresponding group, and obtain 2% 2C3% 2C5-trifluoro-4-cyanophenyl group.
Second, the method of functional group conversion can be adopted. Find a phenyl compound containing multiple convertible functional groups, and first modify some of its functional groups to gradually form a fluorinated structure. For example, the existing functional group on the benzene ring is changed into a group that can be easily fluorinated through a series of reactions, and then the fluorination reaction is carried out. When the fluorine atom is in place, it is skillfully converted to make another functional group into a cyano group. This process requires strict observation of the reaction conditions at each step to make the conversion accurate and efficient.
Third, it may be formed by cyclization. Take a compound containing a specific carbon chain and functional group, make it cyclized, and construct the prototype of the benzene ring. At the time of cyclization, it may already contain some fluorine atoms, or reserve a check point that can introduce fluorine and cyano groups. After cyclization, it is modified to introduce the remaining fluorine atoms and cyano groups. This approach requires a deep understanding of the cyclization reaction mechanism and the ability to precisely design the structure of the starting compound in order to achieve the goal.
All these production methods require craftsmen to study the principles of the reaction and control the conditions to achieve the purity and abundance of the prepared material.
What should be paid attention to when storing and transporting 2,3,5-trichloro-4-fluoronitrobenzene?
2% 2C3% 2C5-trifluoro-4-cyanophenyl This substance should be well attended to during storage and transportation.
First environmental conditions. Its nature may be affected by temperature and humidity, so it should be stored in a cool, dry and well-ventilated place. If the temperature is high and humid, it may cause its characters to mutate, or cause chemical reactions, which will damage its quality. When transporting, it is also necessary to ensure a stable environment, protected from direct sunlight and extreme temperature changes.
The second is that the packaging is tight. It must be filled with suitable packaging materials to prevent leakage. Because of its particularity, once it leaks, it may cause environmental pollution and endanger personal safety. The packaging should be able to withstand external impact and not be damaged during bumpy transportation.
Furthermore, it is related to isolated storage. It should not be stored and transported with reactive substances, such as strong oxidizers, strong acids and alkalis. Such substances meet with it, or react violently, causing explosion and other risks.
Safety measures are indispensable during transportation. Drivers and passengers should be familiar with the characteristics of this object and the methods of emergency response. The means of transportation must be equipped with corresponding fire and leakage emergency equipment to be in case of danger.
Regular inspection is also necessary when storing. Check whether the packaging is damaged and whether the properties are changed. If there is any abnormality, take measures quickly to prevent it from developing. In this way, 2% 2C3% 2C5-trifluoro-4-cyanobenzene is guaranteed to be safe during storage and transportation.
First environmental conditions. Its nature may be affected by temperature and humidity, so it should be stored in a cool, dry and well-ventilated place. If the temperature is high and humid, it may cause its characters to mutate, or cause chemical reactions, which will damage its quality. When transporting, it is also necessary to ensure a stable environment, protected from direct sunlight and extreme temperature changes.
The second is that the packaging is tight. It must be filled with suitable packaging materials to prevent leakage. Because of its particularity, once it leaks, it may cause environmental pollution and endanger personal safety. The packaging should be able to withstand external impact and not be damaged during bumpy transportation.
Furthermore, it is related to isolated storage. It should not be stored and transported with reactive substances, such as strong oxidizers, strong acids and alkalis. Such substances meet with it, or react violently, causing explosion and other risks.
Safety measures are indispensable during transportation. Drivers and passengers should be familiar with the characteristics of this object and the methods of emergency response. The means of transportation must be equipped with corresponding fire and leakage emergency equipment to be in case of danger.
Regular inspection is also necessary when storing. Check whether the packaging is damaged and whether the properties are changed. If there is any abnormality, take measures quickly to prevent it from developing. In this way, 2% 2C3% 2C5-trifluoro-4-cyanobenzene is guaranteed to be safe during storage and transportation.
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