Linshang Chemical
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2,3,5-Trichlorobenzeneboronic Acid
Linshang Chemical
|
HS Code |
711882 |
| Chemical Formula | C6H3BCl3O2 |
| Molar Mass | 239.26 g/mol |
| Appearance | Solid (Typical appearance) |
| Purity | Typical high - purity grade available, e.g., 95%+ |
| Solubility In Organic Solvents | Soluble in some common organic solvents like dichloromethane, toluene |
| Melting Point | Typical range: 145 - 149 °C |
| Boiling Point | Decomposes before boiling in normal conditions |
| Stability | Stable under normal storage conditions, away from strong oxidizing agents |
| Hazard Class | Irritant, may cause skin, eye and respiratory irritation |
| Application | Used in organic synthesis, e.g., Suzuki - Miyaura coupling reactions |
As an accredited 2,3,5-Trichlorobenzeneboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100g of 2,3,5 - trichlorobenzeneboronic Acid packaged in a sealed plastic bag. |
| Storage | 2,3,5 - Trichlorobenzeneboronic Acid should be stored in a cool, dry place. Keep it in a tightly - sealed container to prevent moisture absorption and exposure to air, which could potentially lead to degradation. Store away from heat sources and incompatible substances such as strong oxidizing agents. This helps maintain its chemical integrity for reliable use in various applications. |
| Shipping | 2,3,5 - Trichlorobenzeneboronic Acid is shipped in sealed, corrosion - resistant containers. It must be transported in accordance with hazardous chemical regulations, ensuring proper labeling and safe handling during transit. |
Competitive 2,3,5-Trichlorobenzeneboronic Acid prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2,3,5-Trichlorobenzeneboronic Acid in China?
As a trusted 2,3,5-Trichlorobenzeneboronic Acid manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2,3,5-Trichlorobenzeneboronic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the chemical properties of 2,3,5-trichlorophenylboronic acid?
2% 2C3% 2C5-trifluorobenzoic acid has different chemical properties and has its unique performance in various reactions.
Its properties are acidic, and it can neutralize with bases because of the carboxyl group. In case of sodium hydroxide, it melts into the corresponding salt and water, which is a sign of carboxylic acid universality. Its acidity is stronger than that of ordinary benzoic acids, and the fluoride atom has strong electron absorption, making the hydrogen of the carboxyl group more easily dissociated, which is due to electronic effects.
And because of its fluorine atom, its physical properties are also specific. The introduction of fluorine atoms increases the polarity of its molecules, and the solubility and affinity with water and organic solvents change. Its boiling point and melting point are also different from ordinary products due to the influence of fluorine atoms.
In the field of organic synthesis, 2% 2C3% 2C5 -trifluorobenzoic acid is often the key raw material. Its carboxyl group can be converted into ester group, amide group and other functional groups through many reactions. The corresponding esters can be obtained by co-heating with alcohols under acid catalysis. The ester products are widely used in fragrance, medicine and other industries.
And the fluorine atoms on its benzene ring, although it is difficult to undergo electrophilic substitution reaction, can also interact with nucleophiles under certain conditions. This unique reactivity provides a different path for organic synthesis, and can build many novel compounds, which is of great significance in the creation of new drugs and the development of new materials. Due to its unique chemical properties, it has attracted much attention in the research and industrial production of organic chemistry, and is valued by many scientific researchers and production workers.
Its properties are acidic, and it can neutralize with bases because of the carboxyl group. In case of sodium hydroxide, it melts into the corresponding salt and water, which is a sign of carboxylic acid universality. Its acidity is stronger than that of ordinary benzoic acids, and the fluoride atom has strong electron absorption, making the hydrogen of the carboxyl group more easily dissociated, which is due to electronic effects.
And because of its fluorine atom, its physical properties are also specific. The introduction of fluorine atoms increases the polarity of its molecules, and the solubility and affinity with water and organic solvents change. Its boiling point and melting point are also different from ordinary products due to the influence of fluorine atoms.
In the field of organic synthesis, 2% 2C3% 2C5 -trifluorobenzoic acid is often the key raw material. Its carboxyl group can be converted into ester group, amide group and other functional groups through many reactions. The corresponding esters can be obtained by co-heating with alcohols under acid catalysis. The ester products are widely used in fragrance, medicine and other industries.
And the fluorine atoms on its benzene ring, although it is difficult to undergo electrophilic substitution reaction, can also interact with nucleophiles under certain conditions. This unique reactivity provides a different path for organic synthesis, and can build many novel compounds, which is of great significance in the creation of new drugs and the development of new materials. Due to its unique chemical properties, it has attracted much attention in the research and industrial production of organic chemistry, and is valued by many scientific researchers and production workers.
What are the main uses of 2,3,5-trichlorophenylboronic acid?
2% 2C3% 2C5-trifluorobenzoic acid is an important raw material for organic synthesis and has a wide range of uses in many fields.
In the field of medicinal chemistry, its role is quite critical. It can be used as a key intermediate to synthesize a variety of specific drugs. For example, in the preparation of some anti-cancer drugs, 2% 2C3% 2C5-trifluorobenzoic acid is involved. After a series of chemical reactions, it can construct molecular structures with specific pharmacological activities, providing help to overcome cancer problems. Or some antibacterial drugs, with their unique chemical properties, improve the antibacterial effect and stability of drugs and fight against bacterial infections.
In the field of materials science, it also has extraordinary performance. Can be used to prepare high-performance polymer materials. Introducing 2% 2C3% 2C5-trifluorobenzoic acid into the polymer structure can significantly improve the heat resistance, chemical corrosion resistance and mechanical properties of the material. For example, high-performance composites used in the aerospace field can maintain good performance in extreme environments and ensure the safe and stable operation of aircraft.
In the field of pesticides, it is also indispensable. As an important raw material for the synthesis of new pesticides, 2% 2C3% 2C5-trifluorobenzoic acid can give pesticides unique insecticidal, bactericidal or herbicidal activities. And its structural characteristics help to improve the stability and biodegradability of pesticides in the environment, reduce the harm to the environment, and achieve sustainable agricultural development.
In organic synthetic chemistry, 2% 2C3% 2C5-trifluorobenzoic acid, as a unique functionalization reagent, can participate in various organic reactions, such as esterification and acylation reactions, providing an effective way to construct complex organic molecular structures and promoting the continuous development and innovation of organic synthetic chemistry.
In the field of medicinal chemistry, its role is quite critical. It can be used as a key intermediate to synthesize a variety of specific drugs. For example, in the preparation of some anti-cancer drugs, 2% 2C3% 2C5-trifluorobenzoic acid is involved. After a series of chemical reactions, it can construct molecular structures with specific pharmacological activities, providing help to overcome cancer problems. Or some antibacterial drugs, with their unique chemical properties, improve the antibacterial effect and stability of drugs and fight against bacterial infections.
In the field of materials science, it also has extraordinary performance. Can be used to prepare high-performance polymer materials. Introducing 2% 2C3% 2C5-trifluorobenzoic acid into the polymer structure can significantly improve the heat resistance, chemical corrosion resistance and mechanical properties of the material. For example, high-performance composites used in the aerospace field can maintain good performance in extreme environments and ensure the safe and stable operation of aircraft.
In the field of pesticides, it is also indispensable. As an important raw material for the synthesis of new pesticides, 2% 2C3% 2C5-trifluorobenzoic acid can give pesticides unique insecticidal, bactericidal or herbicidal activities. And its structural characteristics help to improve the stability and biodegradability of pesticides in the environment, reduce the harm to the environment, and achieve sustainable agricultural development.
In organic synthetic chemistry, 2% 2C3% 2C5-trifluorobenzoic acid, as a unique functionalization reagent, can participate in various organic reactions, such as esterification and acylation reactions, providing an effective way to construct complex organic molecular structures and promoting the continuous development and innovation of organic synthetic chemistry.
What is the synthesis method of 2,3,5-trichlorophenylboronic acid?
The synthesis of 2% 2C3% 2C5-trifluorobenzoic acid is an important problem in organic synthesis. To make this acid, many paths are often followed.
First, halogenated aromatic hydrocarbons are used as the beginning. Take halobenzene-containing derivatives and react with magnesium to form Grignard reagent, followed by carbon dioxide to introduce carboxyl groups. After acidification, benzoic acid derivatives can be obtained. If the halogen atom is fluorine, and at a specific position, under suitable reaction conditions, it can reach 2,3,5-trifluorobenzoic acid. In this way, the reaction conditions need to be strictly selected to control the selectivity of the metallization step to avoid side reactions.
Second, fluorobenzene is used as the base. After the Fourier-gram reaction, an appropriate substituent is introduced, and the side chain is oxidized to a carboxyl group. For example, fluorobenzene and acyl halide or acid anhydride are first reacted with Fourier-gram acylation under the catalysis of Lewis acid to obtain acyl-containing benzene derivatives. Then a strong oxidant, such as potassium permanganate, is used to oxidize the acyl group to a carboxyl group to obtain the target product. In this process, the localization effect of the Fourier-gram reaction and the control of the conditions of the oxidation step are crucial.
Third, fluorine-containing heterocyclic compounds are used. Some fluorine-containing heterocyclic rings can be converted into 2,3,5-trifluorobenzoic acid through a series of reactions such as ring opening and rearrangement. Such methods require in-depth knowledge of heterocyclic chemistry and precise design of reaction routes to achieve efficient synthesis.
In short, the synthesis of 2,3,5-trifluorobenzoic acid requires considering the availability of raw materials, the difficulty of reaction, cost and yield and other factors, weighing the appropriate method, and carefully designing the reaction steps.
First, halogenated aromatic hydrocarbons are used as the beginning. Take halobenzene-containing derivatives and react with magnesium to form Grignard reagent, followed by carbon dioxide to introduce carboxyl groups. After acidification, benzoic acid derivatives can be obtained. If the halogen atom is fluorine, and at a specific position, under suitable reaction conditions, it can reach 2,3,5-trifluorobenzoic acid. In this way, the reaction conditions need to be strictly selected to control the selectivity of the metallization step to avoid side reactions.
Second, fluorobenzene is used as the base. After the Fourier-gram reaction, an appropriate substituent is introduced, and the side chain is oxidized to a carboxyl group. For example, fluorobenzene and acyl halide or acid anhydride are first reacted with Fourier-gram acylation under the catalysis of Lewis acid to obtain acyl-containing benzene derivatives. Then a strong oxidant, such as potassium permanganate, is used to oxidize the acyl group to a carboxyl group to obtain the target product. In this process, the localization effect of the Fourier-gram reaction and the control of the conditions of the oxidation step are crucial.
Third, fluorine-containing heterocyclic compounds are used. Some fluorine-containing heterocyclic rings can be converted into 2,3,5-trifluorobenzoic acid through a series of reactions such as ring opening and rearrangement. Such methods require in-depth knowledge of heterocyclic chemistry and precise design of reaction routes to achieve efficient synthesis.
In short, the synthesis of 2,3,5-trifluorobenzoic acid requires considering the availability of raw materials, the difficulty of reaction, cost and yield and other factors, weighing the appropriate method, and carefully designing the reaction steps.
What are the precautions for storing and transporting 2,3,5-trichlorophenylboronic acid?
2% 2C3% 2C5-trifluorobenzoic acid needs to pay attention to many key matters when storing and transporting.
This is a substance with specific chemical properties. When storing, the first choice is the environment. It should be placed in a cool, dry and well-ventilated place. Because it is very sensitive to heat and humidity, high temperature and humid environment can easily cause its chemical properties to change, and even cause deterioration. If placed in a hot and humid place, it may cause chemical reactions due to moisture intrusion and temperature, resulting in a decrease in its purity and affecting subsequent use.
In addition, storage containers are also crucial. Suitable containers must be selected, preferably made of corrosion-resistant materials, such as specific glass materials or special plastic materials. Because of its corrosiveness, ordinary material containers may be eroded, causing damage to the container and material leakage, which is not only wasted, but also causes safety accidents.
When transporting, it is important to stabilize the packaging. Proper protective measures should be taken to prevent packaging damage due to bumps and collisions during transportation. And it is necessary to strictly follow the relevant transportation regulations and operate according to the transportation requirements of hazardous chemicals. Because it is a specific hazardous chemical, transportation qualifications, transportation routes, transportation time, etc. are strictly limited. If it is not transported in accordance with regulations or faces legal risks, it is easier to cause safety problems during transportation, endangering the safety of personnel and the environment.
Transportation personnel also need professional training, familiar with the characteristics of the substance and emergency treatment methods. In the event of an accident such as a leak during transportation, it can be responded to quickly and correctly to reduce the hazard.
In conclusion, 2% 2C3% 2C5-trifluorobenzoic acid is critical in storage and transportation, and the environment, containers, packaging, regulatory compliance, and personnel training must be treated with caution to ensure safety and material quality.
This is a substance with specific chemical properties. When storing, the first choice is the environment. It should be placed in a cool, dry and well-ventilated place. Because it is very sensitive to heat and humidity, high temperature and humid environment can easily cause its chemical properties to change, and even cause deterioration. If placed in a hot and humid place, it may cause chemical reactions due to moisture intrusion and temperature, resulting in a decrease in its purity and affecting subsequent use.
In addition, storage containers are also crucial. Suitable containers must be selected, preferably made of corrosion-resistant materials, such as specific glass materials or special plastic materials. Because of its corrosiveness, ordinary material containers may be eroded, causing damage to the container and material leakage, which is not only wasted, but also causes safety accidents.
When transporting, it is important to stabilize the packaging. Proper protective measures should be taken to prevent packaging damage due to bumps and collisions during transportation. And it is necessary to strictly follow the relevant transportation regulations and operate according to the transportation requirements of hazardous chemicals. Because it is a specific hazardous chemical, transportation qualifications, transportation routes, transportation time, etc. are strictly limited. If it is not transported in accordance with regulations or faces legal risks, it is easier to cause safety problems during transportation, endangering the safety of personnel and the environment.
Transportation personnel also need professional training, familiar with the characteristics of the substance and emergency treatment methods. In the event of an accident such as a leak during transportation, it can be responded to quickly and correctly to reduce the hazard.
In conclusion, 2% 2C3% 2C5-trifluorobenzoic acid is critical in storage and transportation, and the environment, containers, packaging, regulatory compliance, and personnel training must be treated with caution to ensure safety and material quality.
What is the market price range for 2,3,5-trichlorophenylboronic acid?
2% 2C3% 2C5-trifluorobenzoic acid, the price range of the market, it is difficult to determine a definite number. Its price often varies with the supply and demand of the market, the quality of quality, the amount of production, and the difficulty of production.
Looking at the current market, if the quality of 2% 2C3% 2C5-trifluorobenzoic acid is good, the supply is less and the demand is more, and the price may increase. However, if the quality is poor, or if the supply is more and the demand is less, the price may drop.
In the market of chemical raw materials, the price is constant. In general, the price per kilogram is between hundreds and thousands of yuan. If the quantity is small, the buyer is retail, and the price is always high; if the quantity is large, the wholesale style is used, and the price may be reduced.
And, in different places, the price is also different. In places where the economy is complex and the demand is large, the price may be different from that in remote places. And the emergence of new technologies can increase the production and volume, and can also cause changes in the price. Therefore, in order to know the exact price, it is necessary to carefully observe the state of the market and consult the merchants to obtain a more accurate number.
Looking at the current market, if the quality of 2% 2C3% 2C5-trifluorobenzoic acid is good, the supply is less and the demand is more, and the price may increase. However, if the quality is poor, or if the supply is more and the demand is less, the price may drop.
In the market of chemical raw materials, the price is constant. In general, the price per kilogram is between hundreds and thousands of yuan. If the quantity is small, the buyer is retail, and the price is always high; if the quantity is large, the wholesale style is used, and the price may be reduced.
And, in different places, the price is also different. In places where the economy is complex and the demand is large, the price may be different from that in remote places. And the emergence of new technologies can increase the production and volume, and can also cause changes in the price. Therefore, in order to know the exact price, it is necessary to carefully observe the state of the market and consult the merchants to obtain a more accurate number.
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