2,3-Dichloro-1-Methyl-4-(Trifluoromethyl)Benzene

Linshang Chemical

Specifications

HS Code

741409

Chemical Formula C8H5Cl2F3
Molecular Weight 227.025
Appearance Typically a colorless to light - colored liquid
Solubility Insoluble in water, soluble in organic solvents like ethanol, acetone, etc.
Vapor Pressure Low vapor pressure at room temperature
Odor May have a characteristic, pungent, aromatic odor

As an accredited 2,3-Dichloro-1-Methyl-4-(Trifluoromethyl)Benzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500 - gram bottle packaging for 2,3 - dichloro - 1 - methyl - 4 - (trifluoromethyl)benzene.
Storage 2,3 - dichloro - 1 - methyl - 4 - (trifluoromethyl)benzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly - sealed container, preferably made of corrosion - resistant materials like stainless steel or certain plastics. Store it separately from oxidizing agents and incompatible substances to prevent reactions.
Shipping 2,3 - dichloro - 1 - methyl - 4 - (trifluoromethyl)benzene is shipped in accordance with strict chemical transport regulations. It's packed in specialized containers to prevent leakage, and transported via methods ensuring safety during transit.
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2,3-Dichloro-1-Methyl-4-(Trifluoromethyl)Benzene 2,3-Dichloro-1-Methyl-4-(Trifluoromethyl)Benzene
General Information
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Frequently Asked Questions

As a leading 2,3-Dichloro-1-Methyl-4-(Trifluoromethyl)Benzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 2,3-dichloro-1-methyl-4- (trifluoromethyl) benzene?
2% 2C3-difluoro-1-methyl-4- (trifluoromethyl) benzene, which has a wide range of uses. In the field of pharmaceutical synthesis, it is often used as a key intermediate. For example, in the creation of new antidepressant drugs, its structural properties can help build a drug activity skeleton, which can be linked to other functional groups by chemical modification to generate compounds with specific pharmacological activities, thus bringing benefits to depression patients.
In the field of materials science, it can participate in the preparation of high-performance polymer materials. Due to its fluorine-containing groups, it can endow materials with excellent chemical resistance, low surface energy and excellent thermal stability. The polymer containing this ingredient can effectively resist the erosion of various chemical media and prolong the service life of the equipment. It is used to make hydrophobic and oleophobic coatings, which are applied to the surface of objects to make them have excellent self-cleaning performance.
In the research and development of pesticides, it is also an important raw material. Fluorinated pesticides usually have the advantages of high efficiency, low toxicity and low residue. Pesticides developed based on 2% 2C3-difluoro-1-methyl-4 - (trifluoromethyl) benzene can accurately act on specific targets of pests, kill pests efficiently, and have little impact on the environment and non-target organisms, effectively ensuring the sustainable development of agricultural production.
What are the physical properties of 2,3-dichloro-1-methyl-4- (trifluoromethyl) benzene?
2% 2C3-dideuterium-1-methyl-4- (trifluoromethyl) benzene is a kind of organic compound. Its physical properties have various characteristics, which are described as follows:
First of all, its phase state and appearance are discussed. Under normal temperature and pressure, this substance is mostly colorless to light yellow liquid, which is clear and transparent, and has no visible impurities. This form is convenient for transfer and measurement in many chemical operations and reactions.
times and boiling point. The boiling point of this compound is in a specific range, and this value is closely related to the intermolecular force. The atoms in the molecule are connected by chemical bonds to form a specific structure, and there are van der Waals forces and other interactions between molecules. Because its structure contains deuterium atoms and trifluoromethyl groups, it changes the size of the intermolecular force, causing the boiling point to exhibit a unique value, causing it to undergo gas-liquid transformation at a specific temperature.
The other is the melting point. The melting point represents the temperature at which a substance changes from a solid state to a liquid state. For this compound, its melting point also depends on the structural characteristics. The regularity of the molecular structure and the interaction between atoms together determine the size of the lattice energy, which affects the melting point. The structural characteristics of 2% 2C3-dideuterium-1-methyl-4- (trifluoromethyl) benzene give it a specific melting point. At the corresponding temperature, the lattice structure is destroyed, and the substance melts from a solid state to a liquid state.
Density is also one of the important physical properties. The density of this compound is relatively stable, reflecting the mass of the substance per unit volume. The density value is affected by factors such as molecular weight and the degree of intermolecular arrangement. The deuterium atom contained in it is slightly larger than that of the hydrogen atom, and the introduction of trifluoromethyl also affects the molecular mass and spatial arrangement, so the density of the substance is determined.
In terms of solubility, 2% 2C3 -dideuterium-1-methyl-4 - (trifluoromethyl) benzene exhibits different solubility in organic solvents. Generally speaking, it is easily soluble in non-polar or weakly polar organic solvents, such as toluene, dichloromethane, etc. This is based on the principle of similar miscibility. The molecular structure of the compound has certain non-polar characteristics, and it can interact with the molecules of the non-polar solvent through van der Waals force to achieve dissolution. However, in polar solvents such as water, the solubility is poor. Due to the strong hydrogen bonding between water molecules, it is difficult to form a uniform dispersion system due to the mismatch between the molecular forces of the compound.
In summary, the physical properties of 2% 2C3-dideuterium-1-methyl-4- (trifluoromethyl) benzene are influenced by its molecular structure, and the properties are interrelated, which is of great significance for its application and research in the field of chemistry.
What are the chemical properties of 2,3-dichloro-1-methyl-4- (trifluoromethyl) benzene?
2% 2C3-difluoro-1-methyl-4- (trifluoromethyl) benzene is one of the organic compounds. Its chemical properties are quite unique, let me tell you in detail.
In this compound, the introduction of fluorine atoms greatly changes its physical and chemical properties. Fluorine atoms have strong electronegativity, which changes the electron cloud distribution of the molecule, thereby affecting its reactivity.
In terms of its stability, the carbon-fluorine bond energy formed between fluorine atoms and carbon atoms is quite high, which makes the compound have certain thermal and chemical stability. Under common mild conditions, it is difficult to decompose or other violent chemical reactions.
Talking about reactivity, because the benzene ring has substituents such as methyl and trifluoromethyl, which will affect the electron cloud density of the benzene ring. Methyl is the power supply group, which can increase the electron cloud density of the ortho and para-sites of the benzene ring; while trifluoromethyl is a strong electron-absorbing group, which will reduce the electron cloud density of the benzene ring, especially its ortho and para-sites. This electronic effect causes the compound to exhibit unique reaction check point selectivity in the electrophilic substitution reaction.
In the electrophilic substitution reaction, the electrophilic reagent is more inclined to attack the neighboring and para-sites of the methyl group. Due to the power supply of the methyl group, the electron cloud density at these locations is relatively high, and it is easier to bind with the electrophilic reagent. However, the presence of trifluoromethyl will inhibit the progress of the electrophilic substitution reaction to a certain extent. Its electron-absorbing effect will reduce the electron cloud density of the benzene ring as a whole, making it difficult for the electrophilic reagent to attack.
In terms of redox reaction, the compound is relatively stable and generally not easy to be oxidized or reduced. Due to the stability of the carbon-fluorine bond, the fluorine atom is difficult to be easily replaced by other atoms or groups, which in turn affects
In summary, 2% 2C3-difluoro-1-methyl-4- (trifluoromethyl) benzene has unique chemical properties due to its special molecular structure, which may show unique uses and values in organic synthesis and other fields.
What is the synthesis method of 2,3-dichloro-1-methyl-4- (trifluoromethyl) benzene?
To prepare 2,3-difluoro-1-methyl-4- (trifluoromethyl) benzene, the method is as follows:
First take a suitable starting material and perform a nucleophilic substitution reaction with a fluorine-containing reagent. If halogenated aromatics are selected, the halogen atoms can be replaced by fluoride ions. In this step, suitable solvents and catalysts need to be selected. Commonly used solvents include polar aprotic solvents, such as dimethyl sulfoxide, N, N-dimethylformamide, etc., and catalysts such as crown ethers can help fluoride ions to improve the activity and make the substitution reaction occur smoothly.
Next, methyl and trifluoromethyl are introduced under specific conditions. Methylation reagents can be used to introduce methyl groups, such as iodomethane. In the presence of a base, it can react with intermediates. Potassium carbonate can be used to promote the reaction to generate methylation products.
As for the introduction of trifluoromethyl groups, trifluoromethylation reagents can be used, such as trifluoromethyl halide zinc, etc. This process requires precise temperature control and reaction time. Due to the harsh reaction conditions of trifluoromethylation, high or low temperature, too long or too short time can affect the yield and purity of the product.
After each step of the reaction, a suitable separation and purification method should be used to obtain pure intermediates and final products. Commonly used methods include distillation, recrystallization, column chromatography, etc. Distillation can be separated according to the difference in boiling point of each component; recrystallization can be purified according to the different solubility of the substance in different solvents; column chromatography can be separated according to the difference in the interaction between the substance and the stationary phase and the mobile phase. In this way, through multi-step reaction and fine operation, 2,3-difluoro-1-methyl-4 - (trifluoromethyl) benzene can be obtained.
What are the precautions for storing and transporting 2,3-dichloro-1-methyl-4- (trifluoromethyl) benzene?
2% 2C3-difluoro-1-methyl-4- (trifluoromethyl) benzene is one of the organic compounds. When storing and transporting, pay attention to many matters to ensure its safety.
First words storage. This substance should be placed in a cool, dry and well ventilated place. Because of its nature or sensitive to temperature and humidity, if it is in a warm and humid place, it may cause chemical changes and damage its quality. And it needs to be kept away from fire and heat sources. Open flames and hot topics can lead to dangerous reactions and must be prevented. The storage place should be equipped with suitable containment materials to prevent leakage and can be disposed of in time to prevent the spread of harm. In addition, it needs to be stored separately from oxidants, acids, alkalis, etc. Because of its chemical activity, it is mixed with various substances and is prone to chemical reactions and accidents.
As for transportation, there are also many points. Before transportation, it is necessary to ensure that the packaging is complete and sealed to prevent leakage. The selected means of transportation should be clean, dry, and do not react with the substance. During transportation, always pay attention to changes in temperature and humidity and adjust it in a timely manner. Drivers and escorts should be familiar with the characteristics of this substance and emergency treatment methods to prevent accidents. If a leak occurs during transportation, do not panic. Quickly evacuate the surrounding personnel, isolate the leakage area, and take corresponding plugging and cleaning measures according to its characteristics.
In short, when storing and transporting 2% 2C3-difluoro-1-methyl-4 - (trifluoromethyl) benzene, many details must be handled carefully to ensure safety and avoid danger.