Linshang Chemical
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2,4,5-Trichlorobenzenesulfonyl Chloride
Linshang Chemical
|
HS Code |
843011 |
| Chemical Formula | C6H2Cl4O2S |
| Molar Mass | 289.95 g/mol |
| Appearance | Solid (usually white or off - white) |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in many organic solvents like dichloromethane, chloroform |
| Melting Point | Typically in a certain range (needs more precise data) |
| Boiling Point | Typically in a certain range (needs more precise data) |
| Density | Needs more precise data |
| Odor | Pungent odor |
| Hazard Class | Corrosive, harmful |
As an accredited 2,4,5-Trichlorobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 100 - gram bottle packaging for 2,4,5 - trichlorobenzenesulfonyl Chloride. |
| Storage | 2,4,5 - Trichlorobenzenesulfonyl chloride should be stored in a cool, dry, and well - ventilated area. Keep it away from heat, flames, and oxidizing agents. Store in a tightly - sealed container to prevent moisture ingress, as it may react with water. Store separately from incompatible substances to avoid potential chemical reactions. |
| Shipping | 2,4,5 - Trichlorobenzenesulfonyl Chloride is a hazardous chemical. Shipping requires proper packaging in accordance with regulations. It must be labeled clearly for its corrosive nature and transported by approved carriers following strict safety protocols. |
Competitive 2,4,5-Trichlorobenzenesulfonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
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Where to Buy 2,4,5-Trichlorobenzenesulfonyl Chloride in China?
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As a leading 2,4,5-Trichlorobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the physical properties of 2,4,5-trichlorobenzenesulfonyl chloride?
2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF, it is one of the organic halides. Its physical properties are unique, as follows:
Under normal temperature and pressure, the 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF is mostly colorless to light yellow liquid form, with a clear appearance, occasionally accompanied by a specific smell. Although this smell is difficult to describe accurately, it has a certain degree of identification.
When it comes to boiling point, due to the characteristics of intermolecular forces, the boiling point is within a certain range. About [X] degrees Celsius, this value fluctuates slightly due to environmental pressure and other factors. The existence of boiling point makes the substance gradually change from liquid to gaseous at a specific temperature, realizing the phase change.
As for the melting point, it is also an important physical property. The melting point of 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF is about [X] degrees Celsius. Under this temperature, the substance solidifies from liquid to solid, and the molecular arrangement tends to be relatively disordered.
In terms of density, compared with water, 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF density [specific value], showing different floating characteristics from water. This density characteristic has a significant impact on many practical application scenarios, such as in liquid-liquid separation, which is based on the stratification phenomenon with other liquids.
Solubility is also key. 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF has good solubility in organic solvents, such as ethanol, ether, etc., and can be well miscible with it. However, the solubility in water is poor. Due to the non-polar characteristics of the molecular structure, it is incompatible with the polarity of water molecules, so it is difficult to dissolve in water.
The above physical properties are interrelated and jointly shape 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF unique physical appearance. Applications in chemical industry, scientific research and many other fields depend on these properties.
Under normal temperature and pressure, the 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF is mostly colorless to light yellow liquid form, with a clear appearance, occasionally accompanied by a specific smell. Although this smell is difficult to describe accurately, it has a certain degree of identification.
When it comes to boiling point, due to the characteristics of intermolecular forces, the boiling point is within a certain range. About [X] degrees Celsius, this value fluctuates slightly due to environmental pressure and other factors. The existence of boiling point makes the substance gradually change from liquid to gaseous at a specific temperature, realizing the phase change.
As for the melting point, it is also an important physical property. The melting point of 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF is about [X] degrees Celsius. Under this temperature, the substance solidifies from liquid to solid, and the molecular arrangement tends to be relatively disordered.
In terms of density, compared with water, 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF density [specific value], showing different floating characteristics from water. This density characteristic has a significant impact on many practical application scenarios, such as in liquid-liquid separation, which is based on the stratification phenomenon with other liquids.
Solubility is also key. 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF has good solubility in organic solvents, such as ethanol, ether, etc., and can be well miscible with it. However, the solubility in water is poor. Due to the non-polar characteristics of the molecular structure, it is incompatible with the polarity of water molecules, so it is difficult to dissolve in water.
The above physical properties are interrelated and jointly shape 2%2C4%2C5-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF unique physical appearance. Applications in chemical industry, scientific research and many other fields depend on these properties.
What are the chemical properties of 2,4,5-trichlorobenzenesulfonyl chloride?
2% 2C4% 2C5-trifluorobenzoate ethyl ester is an important compound in organic chemistry. It has the following chemical properties:
First of all, its acidity. Due to the existence of carboxyl groups, 2% 2C4% 2C5-trifluorobenzoate ethyl ester is acidic, and the carboxyl group can dissociate hydrogen ions and can neutralize with bases. When encountering bases such as sodium hydroxide, corresponding carboxylic salts and water can be formed. This reaction is like suppressing rigidity. The acidity of carboxyl groups interacts with the alkalinity of bases to reach a new chemical equilibrium.
Second on its nucleophilic substitution reaction. Among ester groups, carbonyl carbons have certain positive electricity and are easily attacked by nucleophiles. In case of alcohol nucleophiles, under suitable conditions, a transesterification reaction can occur, and the original ethyl ester group is replaced by the ester group formed by the new alcohol. This process is like a "transposition game" between chemical substances, and the components are recombined according to chemical laws.
Furthermore, the fluorine atom of 2% 2C4% 2C5 -ethyl trifluorobenzoate has a great influence on its properties. Fluorine atoms have strong electronegativity and significant electron-withdrawing effect, which not only enhances the acidity of carboxyl groups, but also affects the electron cloud distribution and reactivity of molecules. In some reactions, due to its electron-withdrawing effect, the reaction check points of ortho or para-sites can be more susceptible to attack by electrophilic reagents, showing unique reactivity, as if opening up a different path for chemical reactions.
In addition, the compound is relatively stable, but its structure may change under extreme conditions such as high temperature, strong acid or strong base. For example, under the catalysis of strong acid, the ester group may be hydrolyzed to produce 2% 2C4% 2C5-trifluorobenzoic acid and ethanol, just like the delicate structure is disassembled under special external force and returned to more basic chemical components.
First of all, its acidity. Due to the existence of carboxyl groups, 2% 2C4% 2C5-trifluorobenzoate ethyl ester is acidic, and the carboxyl group can dissociate hydrogen ions and can neutralize with bases. When encountering bases such as sodium hydroxide, corresponding carboxylic salts and water can be formed. This reaction is like suppressing rigidity. The acidity of carboxyl groups interacts with the alkalinity of bases to reach a new chemical equilibrium.
Second on its nucleophilic substitution reaction. Among ester groups, carbonyl carbons have certain positive electricity and are easily attacked by nucleophiles. In case of alcohol nucleophiles, under suitable conditions, a transesterification reaction can occur, and the original ethyl ester group is replaced by the ester group formed by the new alcohol. This process is like a "transposition game" between chemical substances, and the components are recombined according to chemical laws.
Furthermore, the fluorine atom of 2% 2C4% 2C5 -ethyl trifluorobenzoate has a great influence on its properties. Fluorine atoms have strong electronegativity and significant electron-withdrawing effect, which not only enhances the acidity of carboxyl groups, but also affects the electron cloud distribution and reactivity of molecules. In some reactions, due to its electron-withdrawing effect, the reaction check points of ortho or para-sites can be more susceptible to attack by electrophilic reagents, showing unique reactivity, as if opening up a different path for chemical reactions.
In addition, the compound is relatively stable, but its structure may change under extreme conditions such as high temperature, strong acid or strong base. For example, under the catalysis of strong acid, the ester group may be hydrolyzed to produce 2% 2C4% 2C5-trifluorobenzoic acid and ethanol, just like the delicate structure is disassembled under special external force and returned to more basic chemical components.
What are the main uses of 2,4,5-trichlorobenzenesulfonyl chloride?
2% 2C4% 2C5 -trifluorobenzoate ethyl ester, its main use, in the context of "Tiangong Kaiwu" in the text as follows:
This substance is widely used in various industrial fields. In the process of organic synthesis, it is often a key raw material. Because of its unique chemical structure, it contains fluorine atoms and endows it with many special properties. It is used to prepare various fine chemicals, which can make the product have excellent properties.
In the field of pharmaceutical chemistry, 2% 2C4% 2C5 -trifluorobenzoate ethyl ester also plays an important role. Pharmaceutical developers often rely on it as a starting material to construct new drug molecules through delicate chemical reactions. Because it can improve the solubility and stability of drugs, and can affect the interaction between drugs and biological targets, it helps to improve the efficacy of drugs.
In the field of materials science, this compound also plays a significant role. With its participation in the preparation of special functional materials, such as fluorine-containing polymer materials. Such materials often have good chemical resistance, low surface energy and excellent thermal stability, and are widely used in coatings, plastics and other industries to improve material quality and performance to meet the needs of different scenarios.
In addition, in the fragrance industry, 2% 2C4% 2C5 -trifluorobenzoate ethyl ester can be used as an intermediate in fragrance synthesis, imparting a unique flavor to fragrances, increasing their aroma level and durability to meet people's diverse pursuit of aroma. Overall, 2% 2C4% 2C5-trifluorobenzoate ethyl ester is an indispensable substance in various industrial fields, which is of great significance for promoting the development of the industry.
This substance is widely used in various industrial fields. In the process of organic synthesis, it is often a key raw material. Because of its unique chemical structure, it contains fluorine atoms and endows it with many special properties. It is used to prepare various fine chemicals, which can make the product have excellent properties.
In the field of pharmaceutical chemistry, 2% 2C4% 2C5 -trifluorobenzoate ethyl ester also plays an important role. Pharmaceutical developers often rely on it as a starting material to construct new drug molecules through delicate chemical reactions. Because it can improve the solubility and stability of drugs, and can affect the interaction between drugs and biological targets, it helps to improve the efficacy of drugs.
In the field of materials science, this compound also plays a significant role. With its participation in the preparation of special functional materials, such as fluorine-containing polymer materials. Such materials often have good chemical resistance, low surface energy and excellent thermal stability, and are widely used in coatings, plastics and other industries to improve material quality and performance to meet the needs of different scenarios.
In addition, in the fragrance industry, 2% 2C4% 2C5 -trifluorobenzoate ethyl ester can be used as an intermediate in fragrance synthesis, imparting a unique flavor to fragrances, increasing their aroma level and durability to meet people's diverse pursuit of aroma. Overall, 2% 2C4% 2C5-trifluorobenzoate ethyl ester is an indispensable substance in various industrial fields, which is of great significance for promoting the development of the industry.
What is the synthesis method of 2,4,5-trichlorobenzenesulfonyl chloride?
The synthesis of 2% 2C4% 2C5-trifluorobenzoic acid is a key problem in the field of chemical preparation. To make this compound, many ways can be followed.
First, the corresponding halobenzoic acid can be obtained by introducing fluorine atoms through a nucleophilic substitution reaction. First, take halobenzoic acid, such as 2-chloro-4-methylbenzoic acid, and add fluoro-containing nucleophiles, such as potassium fluoride, to a suitable reaction vessel. However, this reaction requires a suitable solvent, such as N, N-dimethylformamide (DMF), to help dissolve potassium fluoride and promote the reaction. The reaction needs to be heated to a suitable temperature, such as 150-180 ° C, and stirred continuously to make the reaction sufficient. In this process, fluoride ions will replace halogen atoms. After a multi-step reaction, and then through an appropriate oxidation step, methyl is oxidized to a carboxyl group to obtain 2,4,5-trifluorobenzoic acid.
Second, aromatic hydrocarbons are used as starting materials through a series of electrophilic substitution reactions. If benzene is used as the starting material, a sulfonation reaction is first carried out to introduce a sulfonic acid group to obtain benzenesulfonic acid. Then, through a nitration reaction, a nitro group is introduced at a specific position. Then, through a halogenation reaction, a halogen atom is introduced. Then, through a fluorination reaction, a halogen atom Finally, through hydrolysis, reduction, oxidation and other steps, groups such as sulfonic acid groups are removed, and suitable groups are converted into carboxylic groups to obtain 2,4,5-trifluorobenzoic acid. Although there are many steps in this route, the raw materials are easy to obtain, and if the reaction conditions of each step are properly controlled, it is also an effective synthesis method.
Or the Grignard reagent method can be used. First, Grignard reagents are prepared from halogenated aromatics. For example, Grignard reagents are made from 2-bromo-4-fluorotoluene, and then react with carbon dioxide to generate corresponding carboxylic salts. After acidification, 2-methyl-4-fluorobenzoic acid can be obtained. Subsequently, through suitable halogenation and fluorination reactions, the remaining fluorine atoms are gradually introduced to finally synthesize 2,4,5-trifluorobenzoic acid. This method requires attention to the anhydrous and anaerobic conditions during the preparation of Grignard reagents to ensure the smooth progress of the reaction.
First, the corresponding halobenzoic acid can be obtained by introducing fluorine atoms through a nucleophilic substitution reaction. First, take halobenzoic acid, such as 2-chloro-4-methylbenzoic acid, and add fluoro-containing nucleophiles, such as potassium fluoride, to a suitable reaction vessel. However, this reaction requires a suitable solvent, such as N, N-dimethylformamide (DMF), to help dissolve potassium fluoride and promote the reaction. The reaction needs to be heated to a suitable temperature, such as 150-180 ° C, and stirred continuously to make the reaction sufficient. In this process, fluoride ions will replace halogen atoms. After a multi-step reaction, and then through an appropriate oxidation step, methyl is oxidized to a carboxyl group to obtain 2,4,5-trifluorobenzoic acid.
Second, aromatic hydrocarbons are used as starting materials through a series of electrophilic substitution reactions. If benzene is used as the starting material, a sulfonation reaction is first carried out to introduce a sulfonic acid group to obtain benzenesulfonic acid. Then, through a nitration reaction, a nitro group is introduced at a specific position. Then, through a halogenation reaction, a halogen atom is introduced. Then, through a fluorination reaction, a halogen atom Finally, through hydrolysis, reduction, oxidation and other steps, groups such as sulfonic acid groups are removed, and suitable groups are converted into carboxylic groups to obtain 2,4,5-trifluorobenzoic acid. Although there are many steps in this route, the raw materials are easy to obtain, and if the reaction conditions of each step are properly controlled, it is also an effective synthesis method.
Or the Grignard reagent method can be used. First, Grignard reagents are prepared from halogenated aromatics. For example, Grignard reagents are made from 2-bromo-4-fluorotoluene, and then react with carbon dioxide to generate corresponding carboxylic salts. After acidification, 2-methyl-4-fluorobenzoic acid can be obtained. Subsequently, through suitable halogenation and fluorination reactions, the remaining fluorine atoms are gradually introduced to finally synthesize 2,4,5-trifluorobenzoic acid. This method requires attention to the anhydrous and anaerobic conditions during the preparation of Grignard reagents to ensure the smooth progress of the reaction.
What are the precautions for storing and transporting 2,4,5-trichlorobenzenesulfonyl chloride?
2% 2C4% 2C5 -trifluorobenzoic anhydride is a chemical substance, and many things need to be paid attention to when storing and transporting.
First, when storing, find a cool, dry and well-ventilated place. This is because it has a certain chemical activity. If it is placed in a high temperature, humid place, or causes it to deteriorate, it will affect the quality. As "Tiangong Kaiwu" says, "Hide in dry places to avoid water and fire", due to moisture and high temperature, or cause its chemical reaction, which will damage its original characteristics.
Second, keep away from fire and heat sources. Because of its flammability or combustibility, in case of open flames, hot topics, there is a risk of fire or even explosion. Just as the old saying "prevent problems before they occur, be careful about the proximity of the fire source", it is crucial to control the fire source in its storage environment.
Third, storage needs to be separated from oxidants, reducing agents, acids, alkalis, etc., and mixed storage should not be avoided. This is because different chemical substances occasionally react violently, endangering safety. Just as the ancients kept things, different categories are also separated to prevent mutual influence.
Fourth, when transporting, be sure to ensure that the container does not leak, collapse, fall, or damage. Packaging should meet relevant standards. For example, "Tiangong Kaiwu" is also heavy and firm for the packaging of items. If the packaging is not good for transporting this item, it will not only damage the item, but also pollute the environment and endanger the surroundings.
Fifth, during transportation, it is necessary to prevent exposure to the sun, rain, and high temperature. During the journey, the weather is changeable, and exposure to the sun, rain, and high temperature can affect its stability. In ancient times, transportation also took into account the weather. Nowadays, when transporting this chemical, more attention should be paid to the impact of the weather on it.
Sixth, transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. If there is an emergency on the way, it can be responded to in time to reduce the damage. This is also like a merchant in ancient times, always having tools to deal with it in case of emergency.
First, when storing, find a cool, dry and well-ventilated place. This is because it has a certain chemical activity. If it is placed in a high temperature, humid place, or causes it to deteriorate, it will affect the quality. As "Tiangong Kaiwu" says, "Hide in dry places to avoid water and fire", due to moisture and high temperature, or cause its chemical reaction, which will damage its original characteristics.
Second, keep away from fire and heat sources. Because of its flammability or combustibility, in case of open flames, hot topics, there is a risk of fire or even explosion. Just as the old saying "prevent problems before they occur, be careful about the proximity of the fire source", it is crucial to control the fire source in its storage environment.
Third, storage needs to be separated from oxidants, reducing agents, acids, alkalis, etc., and mixed storage should not be avoided. This is because different chemical substances occasionally react violently, endangering safety. Just as the ancients kept things, different categories are also separated to prevent mutual influence.
Fourth, when transporting, be sure to ensure that the container does not leak, collapse, fall, or damage. Packaging should meet relevant standards. For example, "Tiangong Kaiwu" is also heavy and firm for the packaging of items. If the packaging is not good for transporting this item, it will not only damage the item, but also pollute the environment and endanger the surroundings.
Fifth, during transportation, it is necessary to prevent exposure to the sun, rain, and high temperature. During the journey, the weather is changeable, and exposure to the sun, rain, and high temperature can affect its stability. In ancient times, transportation also took into account the weather. Nowadays, when transporting this chemical, more attention should be paid to the impact of the weather on it.
Sixth, transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. If there is an emergency on the way, it can be responded to in time to reduce the damage. This is also like a merchant in ancient times, always having tools to deal with it in case of emergency.
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