2,4,6-Trichlorobenzenesulphonyl Chloride

Linshang Chemical

Specifications

HS Code

214410

Chemical Formula C6H2Cl4O2S
Molar Mass 285.95 g/mol
Appearance Typically a solid
Physical State At Room Temp Solid
Odor Pungent
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane
Boiling Point Decomposes before boiling
Melting Point 117 - 119 °C
Density Data may vary, but in the range of relatively dense solids
Hazard Class Corrosive, toxic

As an accredited 2,4,6-Trichlorobenzenesulphonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 500g of 2,4,6 - trichlorobenzenesulphonyl chloride packaged in a sealed glass bottle.
Storage 2,4,6 - Trichlorobenzenesulphonyl chloride should be stored in a cool, dry, well - ventilated area. Keep it away from heat, ignition sources, and moisture as it is reactive. Store it in a tightly closed container, preferably made of a material resistant to corrosion, like glass or certain plastics. This prevents decomposition and potential hazardous reactions.
Shipping 2,4,6 - trichlorobenzenesulphonyl chloride is a hazardous chemical. Shipping requires compliance with strict regulations. It must be packaged in suitable containers, labeled clearly, and transported by carriers approved for such chemicals.
Free Quote

Competitive 2,4,6-Trichlorobenzenesulphonyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.

We will respond to you as soon as possible.

Tel: +8615365006308

Email: info@alchemist-chem.com

2,4,6-Trichlorobenzenesulphonyl Chloride 2,4,6-Trichlorobenzenesulphonyl Chloride
General Information
Where to Buy 2,4,6-Trichlorobenzenesulphonyl Chloride in China?
As a trusted 2,4,6-Trichlorobenzenesulphonyl Chloride manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 2,4,6-Trichlorobenzenesulphonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the physical properties of 2,4,6-trichlorobenzenesulfonyl chloride?
2% 2C4% 2C6-trifluorobenzoyl chloride is an important reagent for organic synthesis. Its physical properties are worth exploring.
Looking at its morphology, at room temperature, 2% 2C4% 2C6-trifluorobenzoyl chloride is a colorless to light yellow liquid, with a clear appearance. Under sunlight, it occasionally shimmers slightly, like morning dew on the tip of grass, shining brightly.
Smell its smell, this substance emits a strong and pungent smell, like a spicy thorn, straight into the nasal cavity, which makes people feel uncomfortable and avoid it when smelled.
On its boiling point, it is about 182-184 ° C. When the temperature gradually rises, reaching this range, the substance melts like ice in the spring sun, gradually converts from liquid to gaseous state, and rises.
Its melting point is around -2 ° C, just like the critical point of winter. When the temperature drops, the flowing liquid condenses into a solid state, just like time solidifies.
2% 2C4% 2C6-trifluorobenzoyl chloride has a density heavier than water, about 1.494g/cm ³. If it is placed in one place with water, it will sink like a stone in the abyss and sink straight down.
Furthermore, its solubility is also an important property. In organic solvents such as ether and dichloromethane, 2% 2C4% 2C6-trifluorobenzoyl chloride is easily soluble, just like salt melts in water, disappears instantaneously, and fuses with it; however, in water, it is extremely difficult to dissolve, and the two seem to be distinct and difficult to blend.
The above physical properties play a key role in the application of 2% 2C4% 2C6-trifluorobenzoyl chloride in the field of organic synthesis, and are related to the reaction conditions, process and products. They are indispensable factors in chemical research and production.
What are the chemical properties of 2,4,6-trichlorobenzenesulfonyl chloride?
2% 2C4% 2C6-trifluorobenzoyl chloride is a crucial chemical reagent in organic synthesis. Its chemical properties are unique and have the following numbers:
First, the typical activity of acyl chloride. 2,4,6-trifluorobenzoyl chloride contains an acyl chloride functional group, which has extremely high chemical activity. It is prone to nucleophilic substitution reactions with compounds containing active hydrogen, such as alcohols, phenols, amines, etc. When met with alcohols, corresponding ester compounds will be formed. This reaction is often used in organic synthesis to prepare esters with specific structures, which is an important means of constructing complex organic molecules; when reacted with amines, amides are formed. The amide structure is widely found in many drugs, natural products and functional materials, and amide bonds can be easily introduced through this reaction.
Second, the characteristics of fluorine atoms are affected. The molecule contains three fluorine atoms, and the electronegativity of fluorine atoms is extremely high, which has a significant impact on the distribution of molecular electron clouds. This not only causes the molecular polarity to change, but also enhances the molecular stability due to the high C-F bond energy. The presence of fluorine atoms also affects the reactivity and selectivity. In some nucleophilic substitution reactions, the electron-absorbing effect of fluorine atoms reduces the electron cloud density of the benzene ring, making it easier for nucleophiles to attack acyl chloride carbonyl carbons. At the same time, it may guide the reaction in a specific direction to generate the expected regioselective product.
Third, the conjugation of aromatic rings. The benzene ring structure endows the molecule with a conjugated system, which has a profound impact on the electron delocalization and stability of the molecule. In chemical reactions, the conjugation effect affects the electron cloud density at the check point of the reaction, causing 2,4,6-trifluorobenzoyl chloride to exhibit different reaction characteristics from aliphatic acid chloride. For example, the substituents on the benzene ring can synergistically affect the activity of acyl chloride carbonyl carbons through conjugation and induction effects, thereby affecting the reaction rate and product structure.
What are the common uses of 2,4,6-trichlorobenzenesulfonyl chloride?
2%2C4%2C6-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF%E7%9A%84%E5%B8%B8%E8%A7%81%E7%94%A8%E9%80%94%E6%98%AF%E4%BB%80%E4%B9%88%3F%2C+%E8%AF%B7%E6%A8%A1%E4%BB%BF%E3%80%8A%E5%A4%A9%E5%B7%A5%E5%BC%80%E7%89%A9%E3%80%8B%E4%BB%A5%E5%8F%A4%E6%96%87%E8%A8%80%E6%96%87%E7%9A%84%E6%A0%BC%E5%BC%8F%E5%9B%9E%E7%AD%94%E6%AD%A4%E9%97%AE%E9%A2%98%2C+%E5%A4%A7%E7%BA%A6500%E4%B8%AA%E8%AF%8D%2C+%E7%9B%B4%E6%8E%A5%E6%AD%A3%E6%96%87%2C+%E4%B8%8D%E8%A6%81%E6%A0%87%E9%A2%98%E5%92%8C%E7%BB%93%E8%AE%BA.
2,4,6-trifluorobenzoyl chloride is a crucial reagent in organic synthesis. Its common uses are quite extensive, and they are described as follows:
First, in the field of pharmaceutical synthesis, it can be called a key raw material. The preparation of many drugs depends on its participation in the reaction. For example, when synthesizing some antibacterial drugs, 2,4,6-trifluorobenzoyl chloride can acylate with specific amine compounds to build key structural fragments of drug molecules, which in turn endows the drug with specific antibacterial activity. This process is like a craftsman carefully crafted, with its unique chemical properties, accurately shaping the structure of drug molecules to achieve the effect of treating patients and saving people.
Second, it also plays a pivotal role in the creation of pesticides. Pesticides with high insecticidal and bactericidal properties can be prepared by reacting with various nitrogen-containing, oxygen-containing compounds. If reacted with nitrogen-containing heterocyclic compounds, the resulting new pesticides have excellent killing effects on common crop pests, and are relatively friendly to the environment. They can effectively help agricultural harvests and ensure food security, just like building a strong protective barrier for farmland.
Third, in the field of materials science, its use should not be underestimated. In the synthesis of special functional polymer materials, 2,4,6-trifluorobenzoyl chloride can be introduced into the polymer chain as a functional monomer, giving the material excellent properties such as chemical corrosion resistance and high temperature resistance. This process is like injecting magical power into the material, enabling it to maintain stable performance in harsh environments, and is widely used in high-end fields such as aerospace and electronics.
To sum up, 2,4,6-trifluorobenzoyl chloride plays an indispensable role in many fields such as medicine, pesticides and materials due to its unique chemical activity. It is a treasure of organic synthetic chemistry and promotes the continuous development of related industries.
What are the preparation methods of 2,4,6-trichlorobenzenesulfonyl chloride?
2% 2C4% 2C6-trifluorobenzoyl chloride is an important intermediate in organic synthesis. The common preparation methods are as follows:
First, 2,4,6-trifluorobenzoic acid is used as a raw material to react with thionyl chloride. In this reaction, 2,4,6-trifluorobenzoic acid is placed in a reaction vessel, and the thionyl chloride is slowly added. An appropriate amount of catalyst such as N, N-dimethylformamide is added, and it is warmed to a suitable temperature, generally at 60-80 degrees Celsius, when the reaction number is refluxed. After the reaction is completed, the excess thionyl chloride is removed by distillation to obtain 2,4,6-trifluorobenzoyl chloride. The chemical reaction formula is: $CF_ {3} C_ {6} H_ {2} (OH) _ {3} + SOCl_ {2}\ stackrel {catalyst} {\ longrightarrow} CF_ {3} C_ {6} H_ {2} (COCl) _ {3} + SO_ {2}\ uparrow + HCl\ uparrow $. The raw materials of this method are easy to obtain, the operation is relatively simple, and the yield is quite good.
Second, 2,4,6-trifluorotoluene is used as the starting material, and it is prepared by side chain chlorination, hydrolysis and re-chlorination. First, 2,4,6-trifluorotoluene is reacted with chlorine under the action of light or initiator to obtain 2,4,6-trifluorobenzyl chloride derivatives, and then hydrolyzed to 2,4,6-trifluorobenzoic acid, and then reacted with thionyl chloride as before to obtain the target product. Although this path has many steps, the cost of the raw materials used is low, which is suitable for large-scale preparation.
Third, fluorobenzene is used as the raw material and synthesized through multi-step reaction. First, fluorobenzene is acylated, an acyl group is introduced, and then fluorine atoms are introduced through halogenation reaction, and then converted into 2,4,6-trifluorobenzoyl chloride through a series of reactions. This method requires precise control of reaction conditions and requires high technical requirements, but it can effectively synthesize target products with special structures.
What are the precautions for using 2,4,6-trichlorobenzenesulfonyl chloride?

First of all, this kind of medicine is toxic, and it must be carefully taken and used. When handling it, use anti-pollution equipment, such as gloves, masks, etc., to prevent the skin from being damaged. If you are not careful, use a lot of water as soon as possible to treat it.
Second, the method of survival should also be used. It should be placed in a place where it is dry and clear, and the source of fire and energy should not be oxidized or oxidized.
Third, the amount used must be guided by the right. Use the amount, not only for good, but also for harm. Or cause pollution to the environment, or affect the user's body. And use it in the best way, so that it can be quickly dispersed and prevented from being inhaled by people.
Fourth, use it and properly dispose of it. The remaining products should not be discarded by accident, according to the corresponding regulations, to prevent them from staining the land and water sources. The utensils used should also be cleaned at the bottom for use.

For use, 2%2C4%2C6-%E4%B8%89%E6%B0%AF%E8%8B%AF%E7%A3%BA%E9%85%B0%E6%B0%AF use, toxicity prevention, storage methods, dosage, use and other things, all pay attention to, in order to ensure safety and safety.