2,4-Dichloro-1-Iodobenzene
Linshang Chemical
HS Code |
695800 |
Chemical Formula | C6H3Cl2I |
Molar Mass | 289.899 g/mol |
Appearance | Pale yellow to light brown solid |
Melting Point | 46 - 48 °C |
Boiling Point | 248 - 250 °C |
Density | 1.974 g/cm³ |
Solubility In Water | Insoluble |
Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether, and chloroform |
Flash Point | 110 °C |
Cas Number | 634-93-5 |
Purity | Typically available in high purity (e.g., 95%+) |
As an accredited 2,4-Dichloro-1-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 250 - gram bottle of 2,4 - dichloro - 1 - iodobenzene, tightly sealed for safe storage. |
Storage | 2,4 - dichloro - 1 - iodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances to avoid potential chemical reactions. Label the storage clearly for easy identification and safety compliance. |
Shipping | 2,4 - dichloro - 1 - iodobenzene is shipped in well - sealed, corrosion - resistant containers. Compliance with hazardous chemical shipping regulations is ensured. Temperature - controlled transportation may be required to maintain its stability during transit. |
Competitive 2,4-Dichloro-1-Iodobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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As a leading 2,4-Dichloro-1-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
This compound has a wide range of uses in the field of medicine. It can be used as a key intermediate for the synthesis of many drugs. For example, some compounds with specific physiological activities need to be constructed with 2% 2C4-dihydro-1-naphthol as the starting material, and through multiple steps of delicate chemical reactions, drugs with complex structures and therapeutic effects can be obtained. Due to its unique chemical structure, it can endow the synthesized drugs with specific pharmacological properties, or enhance affinity for specific targets, or improve pharmacokinetic properties, making the drugs easier to be absorbed, distributed, metabolized and excreted by the human body, thereby improving the efficacy and reducing toxic and side effects.
In the field of materials science, it is also indispensable. Can participate in the preparation of high-performance materials. By polymerizing with other monomers or compounds, polymer materials with special properties can be formed. For example, the synthesized polymer may have excellent optical properties and be very useful in optical lenses, optoelectronic devices, etc.; or make the material exhibit good mechanical properties and be used in aerospace, automobile manufacturing and other fields that require strict material strength and stability.
In the field of organic synthetic chemistry, 2% 2C4-dihydro-1-naphthol is a cornerstone. As a multifunctional synthon, it can be derived through various chemical reactions, such as oxidation, reduction, substitution, etc., to generate a wide range of organic compounds with different structures. This provides a wealth of options for organic synthesis chemists to explore new reaction pathways and construct novel organic molecular structures, which greatly promotes the development of organic synthesis chemistry and helps to create more organic compounds with unique functions and application value.
- ** Appearance and Properties **: Under normal temperature and pressure, it is mostly white to light yellow crystalline powder, with fine texture and a typical appearance of solid substances. This form is not only easy to store and transport, but also can exhibit unique reactivity due to its powder properties in specific chemical reactions.
- ** Melting Point and Boiling Point **: The melting point is about 72-76 ° C. When the temperature rises to this range, the substance gradually melts from solid to liquid. This property is crucial in the purification and separation process of the substance. Although the data related to the boiling point may vary depending on the specific experimental conditions, it is roughly within a specific high temperature range. This boiling point characteristic is of great significance for judging its stability and volatility in high temperature environments.
- ** Solubility **: In organic solvents such as dichloromethane, chloroform, toluene, etc., it exhibits good solubility and can be miscibly formed with it to form a uniform solution. However, in water, the solubility is extremely small and almost insoluble. This difference in solubility can be used as an important basis in the extraction and separation steps of organic synthesis to help effectively separate and purify it from the reaction system.
- ** Density **: It has a certain density, although the exact value or the measurement environment varies slightly, it is roughly maintained within a specific range. This density characteristic has a significant impact on operations such as mixing and separation of substances, and is related to the distribution and motion state of substances in the system.
- ** Stability **: Under normal conditions, the chemical properties are relatively stable, and it is not easy to spontaneously undergo violent chemical reactions. However, when encountering specific chemical substances such as strong oxidizing agents, strong acids, and strong bases, or due to chemical reactions, this stability characteristic requires special attention during storage and use. Contact with the above substances should be avoided to prevent deterioration.
Among this substance, fluorine atoms have unique characteristics. Fluorine, an element with strong electronegativity, is also combined with naphthylamine, which can cause changes in the distribution of electron clouds in the molecular structure. Due to the strong electronegativity of fluorine, it has the power to attract the electron cloud of adjacent atoms, which stabilizes the electronic structure of the molecule. Under this effect, the activity of the molecule may decrease, which may also make some chemical reactions difficult.
Furthermore, the basic structure of naphthylamine lays the foundation for its chemical properties. The aromatic system of naphthalene has the property of conjugation, which reduces the molecular energy and increases the stability. When fluorine atoms are introduced into it, although the electron cloud is affected, the conjugation stability of the aromatic system still exists, and the two interact to determine the chemical properties of the molecule.
Under normal conditions, 2% 2C4-difluoro-1-naphthalamine may have certain stability. The electronic effect of fluorine atoms is complementary to the inherent aromatic stability of naphthalamine. However, in case of special reaction conditions, such as strong oxidizing agents, reducing agents, or extreme situations such as high temperature and high pressure, its chemical properties may change significantly. Strong oxidizing agents may break some bonds of their molecular structures, causing oxidation reactions; strong reducing agents may also change their electronic structures, causing chemical reactions to occur.
Therefore, 2% 2C4-difluoro-1-naphthylamine has certain stability under normal circumstances, but in special chemical situations, its stability or challenge, and the chemical properties also change accordingly.
First, the initiation method of halogenation reaction. First, naphthol is used as the initial raw material, and fluorine atoms are carefully introduced through halogenation reaction. Under appropriate reaction conditions, naphthol is treated with specific halogenation reagents. If a fluorine-containing halogenating agent is selected, under conditions such as precise control of temperature, reaction time and solvent environment, the fluorine atom is integrated into the molecular structure of naphthol according to a specific position. This step requires strict control of the reaction conditions. If there is a slight difference in the pool, the product will be impure or the yield will be low.
Second, the construction method of arylation reaction. The fluorine-containing aryl compound is used as the key raw material to combine naphthol through arylation reaction. This process requires the selection of high-efficiency catalysts to optimize the reaction conditions and promote the effective connection of aryl groups and naphthol to construct the target molecular structure. The choice of arylation reaction conditions has a profound impact on the success or failure of the reaction and the characteristics of the product, and various parameters need to be carefully weighed.
Third, transition metal catalysis. With the help of the catalytic activity of transition metals, the reaction process is accelerated and the introduction of fluorine atoms is precisely guided. Transition metal catalysts can significantly reduce the activation energy of the reaction, enabling the reaction to proceed efficiently under relatively mild conditions. In this method, factors such as the type and dosage of the catalyst and the pH of the reaction system need to be fine-tuned to achieve the best reaction effect and obtain a high-purity 2% 2C4-difluoro-1-naphthol product.
Synthesis of 2% 2C4-difluoro-1-naphthol, each method has its own advantages and disadvantages, and it is necessary to carefully select the appropriate synthesis path according to actual needs, such as product purity, cost considerations, ease of control of reaction conditions, etc., in order to achieve efficient and high-quality synthesis goals.
The first priority is safety. This is a chemical, which is dangerous. When storing, be sure to choose a dry, cool and well-ventilated place. Do not approach fire or heat sources to prevent fire and explosion. Because it may be flammable, it is easy to cause danger in case of open flames and hot topics. Therefore, the temperature and humidity of the storage environment must also be precisely controlled. The temperature should be maintained within a specific range, and the humidity should not be too high, so as not to affect its chemical properties.
Furthermore, the packaging must be stable and tight. The transportation process is bumpy and vibrating. If the packaging is not good, it is easy to leak. Leakage not only wastes materials, but even more, it may pollute the environment and endanger the safety of humans and animals. When the packaging material is adapted to the characteristics of the chemical, it can effectively protect it from external factors.
And it needs to be stored and transported in categories. It cannot be mixed with oxidizing agents, acids, alkalis and other substances. Because of its active chemical properties, contact with the above substances may cause severe chemical reactions, resulting in safety accidents.
Labeling is also crucial. On storage containers and transportation vehicles, information such as the name of the chemical, its characteristics, hazards, and emergency treatment methods should be clearly marked. In the event of an accident, relevant personnel can quickly know the countermeasures with the label.
Transportation personnel should also be professionally trained. Familiar with the characteristics of 2% 2C4-dihydro-1-naphthol and emergency response methods. Check regularly during transportation, and deal with any abnormalities in time. In this way, the safety of storage and transportation can be guaranteed.
In the field of materials science, 2% 2C4-dihydro-1-naphthol also has unique uses. It can be used as a synthetic raw material for functional materials, and can be converted into materials with special optical and electrical properties through specific chemical reactions. Such materials have broad application prospects in the fields of optoelectronic devices, such as organic Light Emitting Diodes (OLEDs), or can improve the luminous efficiency and stability of devices, injecting new vitality into the development of optoelectronic devices.
In the field of organic synthetic chemistry, it is an important building block for organic synthesis. With its special chemical structure, chemists can use various organic reactions to cleverly splice it with other organic molecules to construct complex and functional organic compounds. This process is like building a delicate building block, with 2% 2C4-dihydro-1-naphthol as the basic unit, providing rich possibilities for the innovation and development of organic synthetic chemistry.
Overall, 2% 2C4-dihydro-1-naphthol has important uses in many important fields such as medicine, materials science, and organic synthetic chemistry, and is of great significance for promoting technological progress and development in related fields.
Under normal temperature, it often takes the form of white to light yellow crystalline powder, which is easy to store and use, and has high stability. In conventional environments, it rarely produces spontaneous qualitative changes.
When it comes to the melting point, it is about 96 ° C - 99 ° C. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. This specific melting point indicates that the compound is in this temperature range, and the change of intermolecular forces leads to the transformation of the state of matter. Its melting point is relatively moderate, neither extremely easy to melt nor extremely high temperature to melt. This characteristic is of great significance in many chemical operations, such as crystallization, purification, etc., which can achieve ideal separation and refining results based on temperature characteristics.
As for the boiling point, although the relevant data may rarely be fully recorded, it is deduced according to its molecular structure and the characteristics of similar compounds, or it may have a higher boiling point. Because the molecule contains a conjugated system and polar groups, the intermolecular force is strong, and in order to make the substance boil, a large amount of energy needs to be supplied to overcome the intermolecular attractive force, so the boiling point should be in the higher temperature range. This high boiling point characteristic can effectively distinguish the compound from low boiling point impurities in operations such as distillation and separation.
In terms of solubility, it exhibits good solubility in organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. The polarity and molecular structure of the organic solvent are compatible with 2% 2C4-difluoro-1-naphthalonitrile, so that the solute molecules can be uniformly dispersed in the solvent to form a homogeneous system. This good solubility provides a uniform environment for the reaction in the organic synthesis reaction, promotes full contact and reaction between the reactants, and improves the reaction efficiency and yield. In water, its solubility is poor, because the non-polar part of the molecule accounts for a large proportion, and the force between it and the water molecule is weak, making it difficult to break the hydrogen bond between the water molecules and integrate into it.
In addition, the density of the compound is also one of the important physical properties. Although the exact value may vary depending on the measurement conditions, its density is relatively large. In the process of liquid-liquid separation or mixing, the process flow can be reasonably designed according to its density characteristics to ensure the accuracy of material separation and mixing.
In summary, the physical properties of 2% 2C4-difluoro-1-naphthalonitrile are of crucial guiding significance in many fields such as organic synthesis and material preparation, laying a solid foundation for related industrial production and scientific research.
Fluorine atoms have strong electronegativity, which can change the polarity of the molecule. However, at a specific position of the naphthalene ring, due to the action of the conjugate system of the naphthalene ring, the overall stability is limited. Although the hydroxyl group is an active group and can form hydrogen bonds, in this compound, its reactivity is also restricted by the naphthalene ring and fluorine atoms.
Under normal conditions, without specific reagents or environmental stimuli, 2% 2C4-difluoro-1-naphthol is not prone to spontaneous significant chemical reactions. If it is in a normal temperature and pressure, dry and catalyst-free environment, it can maintain its own structure and properties for a long time, and it is difficult to react quickly with common air components such as water vapor and oxygen.
Even in the case of general organic solvents, it can remain relatively stable without special interactions. Therefore, in general, the chemical properties of 2% 2C4-difluoro-1-naphthol are quite stable.
If you want to make 2% 2C4-dideuterium-1-naphthol, you can start from naphthalene. Although the ancient naphthalene production method does not have the precise purification method today, the crude product of naphthalene can be obtained by fractionation of coal tar. First, the coal tar is vaporized at high temperature, and then condensed and collected at different temperatures according to the difference in boiling point.
If you want to introduce deuterium atoms, you can find reagents rich in deuterium. Although there are no pure deuterium sources such as modern heavy water (D2O O) in ancient times, deuterium-containing raw materials can be obtained by enriching trace amounts of deuterium in natural water bodies. Naphthalene can react with deuterium-containing reagents under appropriate conditions.
In the reaction conditions, the ancients used fire to control the temperature. Such as alchemy and metallurgy, the temperature is adjusted by the size of a charcoal fire and the density of ventilation. In this reaction, a moderate temperature can be found to make naphthalene react effectively with deuterium-containing reagents. The power of catalysts can also be used in ancient chemical processes. For example, koji for brewing contains substances that promote the reaction. The reaction of 2% 2C4-dideuterium-1-naphthol can be prepared here, or a suitable product can be found to promote the reaction rate of naphthalene with deuterium-containing reagents and make the reaction proceed in the direction of generating the target product.
After the reaction is completed, the product may be mixed with impurities and needs to be purified. Ancient purification methods, such as crystallization and distillation, can be used. The crystallization method, according to the difference in solubility of substances with temperature, makes the target product crystallize and precipitate, and removes impurities. Distillation, according to different boiling points, separates 2% 2C4-dideuterium-1-naphthol.
Although the preparation method of 2% 2C4-dideuterium-1-naphthol is not detailed in "Tiangong Kaiwu", its chemical process concept and operation methods can inspire the preparation ideas today.
Bear the brunt, temperature and humidity control are crucial. Due to its chemical properties, too high temperature may cause it to decompose and deteriorate, and too humid environment may cause it to be damp, which affects quality. Therefore, when stored in a cool and dry place, the warehouse temperature should be stable in a specific range, and the humidity should also be maintained moderately, so as to ensure the stability of its chemical properties.
Furthermore, it is necessary to avoid contact with oxidants and other substances. 2% 2C4-dihydro-1-naphthol has a specific chemical activity, and it is easy to react violently when exposed to oxidants, or even cause the risk of combustion and explosion. Therefore, when storing and transporting, it is necessary to ensure that it is strictly isolated from oxidant substances, and it is appropriate to store in separate warehouses and transport in separate vehicles.
The tightness of the packaging should not be ignored. High-quality and tight packaging can effectively protect it from external environmental intrusion. The packaging material should have good chemical stability and do not react with 2% 2C4-dihydro-1-naphthol. During transportation, pay attention to whether the packaging is damaged. If there is any damage, immediate measures should be taken to prevent leakage.
In addition, storage and transportation sites should be equipped with complete fire and emergency facilities. In view of its potential danger, in the event of an accident, such as fire, leakage, etc., complete fire equipment and emergency treatment equipment can be responded to in a timely manner to reduce the harm. Staff also need to be professionally trained and familiar with the emergency treatment process, so that they can be dealt with quickly and properly in an emergency.

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