Linshang Chemical
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2,4-Dichloro-3-Fluoronitrobenzene
Linshang Chemical
|
HS Code |
591927 |
| Chemical Formula | C6H2Cl2FNO2 |
| Molar Mass | 209.99 g/mol |
| Appearance | Yellow to light brown solid |
| Melting Point | 44 - 46 °C |
| Boiling Point | 248 - 250 °C |
| Density | 1.57 g/cm³ (estimated) |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, toluene |
| Vapor Pressure | Low vapor pressure at room temperature |
| Flash Point | 110 °C (closed cup, estimated) |
As an accredited 2,4-Dichloro-3-Fluoronitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500 - gram bottles of 2,4 - dichloro - 3 - fluoronitrobenzene, well - sealed for safe storage. |
| Storage | 2,4 - dichloro - 3 - fluoronitrobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and oxidizing agents. Store in a tightly closed container to prevent leakage and exposure to air or moisture. Separate it from incompatible substances to avoid potential chemical reactions. |
| Shipping | 2,4 - dichloro - 3 - fluoronitrobenzene is a chemical. Shipments must follow strict regulations. It should be properly packaged in corrosion - resistant containers, clearly labeled, and transported by carriers licensed for hazardous chemicals. |
Competitive 2,4-Dichloro-3-Fluoronitrobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy 2,4-Dichloro-3-Fluoronitrobenzene in China?
As a trusted 2,4-Dichloro-3-Fluoronitrobenzene manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading 2,4-Dichloro-3-Fluoronitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What are the main uses of 2,4-dichloro-3-fluoronitrobenzene?
2% 2C4-dihydro-3-methoxybenzaldehyde, although this substance is not detailed in Tiangong Kaiji, it is known that it has a wide range of uses according to various books and previous experience.
In the field of medicine, it is often the key raw material for the synthesis of many drugs. Because of its unique structure and specific chemical activity, it can participate in the construction of drug molecules and help synthesize compounds with specific curative effects. For example, some drugs used in the treatment of cardiovascular diseases need to borrow 2% 2C4-dihydro-3-methoxybenzaldehyde to build the core structure during the synthesis process. After subsequent reaction modification, the drug can be targeted for treatment and regulate physiological functions.
In the fragrance industry, it also has an important position. Because of its unique aroma, it can be used to prepare fragrances. It can add a special charm to the fragrance, or increase the flavor level, or give it a unique tone. When making floral fragrances, adding an appropriate amount can make the aroma more mellow and soft, creating a different olfactory experience. It is widely used in perfumes, air fresheners, cosmetics and other products to improve its quality and attractiveness.
In the field of organic synthesis, it is an important intermediate. With its own chemical properties, it can react with a variety of reagents to derive various organic compounds. Through a series of organic reactions, such as nucleophilic substitution, redox, etc., complex organic molecular structures are constructed, providing an important material foundation for the development of organic synthetic chemistry, assisting in the synthesis of new materials, functional compounds, etc., and promoting progress in the field of organic synthesis.
In the field of medicine, it is often the key raw material for the synthesis of many drugs. Because of its unique structure and specific chemical activity, it can participate in the construction of drug molecules and help synthesize compounds with specific curative effects. For example, some drugs used in the treatment of cardiovascular diseases need to borrow 2% 2C4-dihydro-3-methoxybenzaldehyde to build the core structure during the synthesis process. After subsequent reaction modification, the drug can be targeted for treatment and regulate physiological functions.
In the fragrance industry, it also has an important position. Because of its unique aroma, it can be used to prepare fragrances. It can add a special charm to the fragrance, or increase the flavor level, or give it a unique tone. When making floral fragrances, adding an appropriate amount can make the aroma more mellow and soft, creating a different olfactory experience. It is widely used in perfumes, air fresheners, cosmetics and other products to improve its quality and attractiveness.
In the field of organic synthesis, it is an important intermediate. With its own chemical properties, it can react with a variety of reagents to derive various organic compounds. Through a series of organic reactions, such as nucleophilic substitution, redox, etc., complex organic molecular structures are constructed, providing an important material foundation for the development of organic synthetic chemistry, assisting in the synthesis of new materials, functional compounds, etc., and promoting progress in the field of organic synthesis.
What are the synthesis methods of 2,4-dichloro-3-fluoronitrobenzene?
To prepare 2,4-difluoro-3-methoxyphenylboronic acid, there are many methods, each with advantages and disadvantages, and should be carefully selected according to the actual situation.
First, halogenated aromatics are used as starting materials, aryl metal reagents are prepared by metallization, and then reacted with borate esters to obtain the target product. For example, 2,4-difluoro-3-methoxybromobenzene is used as the starting material, and reacts with strong bases such as n-butyl lithium at low temperature to form lithium reagents, and then reacts with trimethyl borate to hydrolyze 2,4-difluoro-3-methoxyphenylboronic acid. The reaction conditions are harsh, requiring low temperature and anhydrous and oxygen-free environment, but the purity of the product is quite high.
Second, the Suzuki reaction is also a commonly used method. 2,4-Difluoro-3-methoxyhalobenzene is reacted with aryl boric acid or borate as raw material under palladium catalysis and alkali action. For example, 2,4-difluoro-3-methoxychlorobenzene and pinacol borate are used as raw materials, tetrakis (triphenylphosphine) palladium is used as catalyst, and potassium carbonate is used as base. The reaction is heated in an organic solvent to obtain the target product. The method has mild conditions and a wide range of substrates, but the catalyst is expensive and the cost is high.
Third, the Grignard reagent method is also feasible. The Grignard reagent is prepared by reacting 2,4-difluoro-3-methoxyhalobenzene with magnesium, and then reacting with borate ester to obtain the product after post-treatment. This method is relatively simple to operate, and the Grignard reagent is sensitive to water and oxygen, so attention should be paid to isolation during preparation and reaction.
In short, there are various methods for synthesizing 2,4-difluoro-3-methoxyphenylboronic acid. In actual synthesis, many factors such as raw material availability, cost, reaction conditions and product purity need to be considered comprehensively to select the optimal route to achieve efficient, economical and environmentally friendly synthesis.
First, halogenated aromatics are used as starting materials, aryl metal reagents are prepared by metallization, and then reacted with borate esters to obtain the target product. For example, 2,4-difluoro-3-methoxybromobenzene is used as the starting material, and reacts with strong bases such as n-butyl lithium at low temperature to form lithium reagents, and then reacts with trimethyl borate to hydrolyze 2,4-difluoro-3-methoxyphenylboronic acid. The reaction conditions are harsh, requiring low temperature and anhydrous and oxygen-free environment, but the purity of the product is quite high.
Second, the Suzuki reaction is also a commonly used method. 2,4-Difluoro-3-methoxyhalobenzene is reacted with aryl boric acid or borate as raw material under palladium catalysis and alkali action. For example, 2,4-difluoro-3-methoxychlorobenzene and pinacol borate are used as raw materials, tetrakis (triphenylphosphine) palladium is used as catalyst, and potassium carbonate is used as base. The reaction is heated in an organic solvent to obtain the target product. The method has mild conditions and a wide range of substrates, but the catalyst is expensive and the cost is high.
Third, the Grignard reagent method is also feasible. The Grignard reagent is prepared by reacting 2,4-difluoro-3-methoxyhalobenzene with magnesium, and then reacting with borate ester to obtain the product after post-treatment. This method is relatively simple to operate, and the Grignard reagent is sensitive to water and oxygen, so attention should be paid to isolation during preparation and reaction.
In short, there are various methods for synthesizing 2,4-difluoro-3-methoxyphenylboronic acid. In actual synthesis, many factors such as raw material availability, cost, reaction conditions and product purity need to be considered comprehensively to select the optimal route to achieve efficient, economical and environmentally friendly synthesis.
What are the physical properties of 2,4-dichloro-3-fluoronitrobenzene?
2% 2C4-difluoro-3-methoxybenzophenone, is a kind of organic compound. Its physical properties are quite characteristic.
Looking at its appearance, it is often white to light yellow crystalline powder, fine and uniform in texture, visible in sunlight Its tiny particles emit a shimmer, like fine stars gathered in one place.
When it comes to the melting point, it is about 56-59 ° C. When the temperature gradually rises, it is like winter ice meeting the warm sun, slowly solidifying from solid to liquid. This process is smooth and orderly, and the accuracy of the melting point provides a key reference for many reactions and applications.
In terms of boiling point, it is roughly 275-277 ° C. If it is heated on fire, when it reaches the boiling point, the liquid will turn into curling steam and rise. This boiling point characteristic determines the control of conditions in separation, purification and other operations.
Solubility is also an important property. It is soluble in organic solvents such as ethanol, ether, and chloroform. In ethanol, such as salt entering water, it dissolves rapidly to form a uniform and transparent solution, while in water it is poorly soluble, just like the difficulty of oil and water. This difference in solubility is of great significance in the extraction, separation, and reaction system construction of substances.
In addition, the density of this substance is about 1.386 g/cm ³, indicating that the mass per unit volume is moderate. When it comes to material quantity and volume calculation, this parameter is indispensable, and it is related to the precise ratio of the reaction and the feasibility of actual operation. Its various physical properties are interrelated and have important uses in organic synthesis, drug development and other fields, laying the foundation for related research and production.
Looking at its appearance, it is often white to light yellow crystalline powder, fine and uniform in texture, visible in sunlight Its tiny particles emit a shimmer, like fine stars gathered in one place.
When it comes to the melting point, it is about 56-59 ° C. When the temperature gradually rises, it is like winter ice meeting the warm sun, slowly solidifying from solid to liquid. This process is smooth and orderly, and the accuracy of the melting point provides a key reference for many reactions and applications.
In terms of boiling point, it is roughly 275-277 ° C. If it is heated on fire, when it reaches the boiling point, the liquid will turn into curling steam and rise. This boiling point characteristic determines the control of conditions in separation, purification and other operations.
Solubility is also an important property. It is soluble in organic solvents such as ethanol, ether, and chloroform. In ethanol, such as salt entering water, it dissolves rapidly to form a uniform and transparent solution, while in water it is poorly soluble, just like the difficulty of oil and water. This difference in solubility is of great significance in the extraction, separation, and reaction system construction of substances.
In addition, the density of this substance is about 1.386 g/cm ³, indicating that the mass per unit volume is moderate. When it comes to material quantity and volume calculation, this parameter is indispensable, and it is related to the precise ratio of the reaction and the feasibility of actual operation. Its various physical properties are interrelated and have important uses in organic synthesis, drug development and other fields, laying the foundation for related research and production.
What is the market price of 2,4-dichloro-3-fluoronitrobenzene?
In today's world, the market is complex, and the price of all kinds of things varies from time to time, from place to place, and is related to the change of supply and demand. It is difficult to determine. As for the product inquired about "2,4-dihydro-3-pentenylnaphthalene", the price of the product in the market cannot be generalized.
This product or the field of chemical and pharmaceutical products, the difficulty of its preparation and the complexity of the materials used affect its value. If the preparation method is simple, the materials used are easy to obtain, and the demand in the market is not strong, the price may be slightly cheaper; on the contrary, if the preparation requires exquisite techniques, the materials used are rare, and there are many people who want it, the price will be high.
Moreover, its price is also influenced by the region. In Dayi, Tongdu, the trade is convergent, the supply of goods is abundant, the competition is fierce, and the price may be flat; while in remote places, transportation is difficult and costs are increased, so the price is higher.
Furthermore, the market situation changes like the situation, and the situation of supply and demand changes rapidly. If there is a sudden increase in users for a while, and the producers do not respond to it, the price will rise; if there is too much demand for production and the goods are in the market, the price will fall.
Therefore, in order to know the exact price of "2,4-dihydro-3-pentenylnaphthalene", it is necessary to carefully investigate the market conditions, consult the merchants, or inquire on the special business platform, in order to obtain a more accurate price, it is difficult to explain its value.
This product or the field of chemical and pharmaceutical products, the difficulty of its preparation and the complexity of the materials used affect its value. If the preparation method is simple, the materials used are easy to obtain, and the demand in the market is not strong, the price may be slightly cheaper; on the contrary, if the preparation requires exquisite techniques, the materials used are rare, and there are many people who want it, the price will be high.
Moreover, its price is also influenced by the region. In Dayi, Tongdu, the trade is convergent, the supply of goods is abundant, the competition is fierce, and the price may be flat; while in remote places, transportation is difficult and costs are increased, so the price is higher.
Furthermore, the market situation changes like the situation, and the situation of supply and demand changes rapidly. If there is a sudden increase in users for a while, and the producers do not respond to it, the price will rise; if there is too much demand for production and the goods are in the market, the price will fall.
Therefore, in order to know the exact price of "2,4-dihydro-3-pentenylnaphthalene", it is necessary to carefully investigate the market conditions, consult the merchants, or inquire on the special business platform, in order to obtain a more accurate price, it is difficult to explain its value.
What are the precautions for storing and transporting 2,4-dichloro-3-fluoronitrobenzene?
2% 2C4-dihydro-3-hydroxymethylquinoline should be used with caution in storage and transportation. This is a fine chemical. Its properties may be unstable, and it can be changed when exposed to heat, light, and moisture.
When stored, it is advisable to choose a cool, dry, and well-ventilated place to avoid open fires and hot topics. Do not co-store with oxidants, acids, and alkalis to prevent their interaction and cause danger. If stored in a container, ensure that it is well sealed to prevent it from being eroded by moisture and air, resulting in quality loss.
When transported, the packaging must be solid and reliable, and marked according to the regulations of dangerous chemicals. The means of transportation should also be clean and dry, with no residue to react with. Protect against sun exposure, rain, and high temperature on the way. When loading and unloading, handle with care to avoid damage to the container and leakage of materials.
In case of leakage, the first thing to do is to evacuate the surrounding personnel, isolate the scene, and strictly prevent fire. Emergency responders must wear protective clothing and protective masks to avoid contact with the skin and eyes. Small leaks can be adsorbed and collected by inert materials such as sand and vermiculite; large leaks need to be embanketed and contained before proper disposal.
Store 2% 2C4-dihydro-3-hydroxymethylquinoline, every step is related to safety and quality, and there should be no slack, so as to keep it safe.
When stored, it is advisable to choose a cool, dry, and well-ventilated place to avoid open fires and hot topics. Do not co-store with oxidants, acids, and alkalis to prevent their interaction and cause danger. If stored in a container, ensure that it is well sealed to prevent it from being eroded by moisture and air, resulting in quality loss.
When transported, the packaging must be solid and reliable, and marked according to the regulations of dangerous chemicals. The means of transportation should also be clean and dry, with no residue to react with. Protect against sun exposure, rain, and high temperature on the way. When loading and unloading, handle with care to avoid damage to the container and leakage of materials.
In case of leakage, the first thing to do is to evacuate the surrounding personnel, isolate the scene, and strictly prevent fire. Emergency responders must wear protective clothing and protective masks to avoid contact with the skin and eyes. Small leaks can be adsorbed and collected by inert materials such as sand and vermiculite; large leaks need to be embanketed and contained before proper disposal.
Store 2% 2C4-dihydro-3-hydroxymethylquinoline, every step is related to safety and quality, and there should be no slack, so as to keep it safe.
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